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Volumn 53, Issue 9, 2012, Pages 787-796

DNA polymerase kappa microsatellite synthesis: Two distinct mechanisms of slippage-mediated errors

Author keywords

DINB1; Frameshift mutation; Microsatellite interruption; POLK; Polymerase fidelity

Indexed keywords

DNA POLYMERASE; DNA POLYMERASE KAPPA; MICROSATELLITE DNA; NUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 84868672661     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21721     Document Type: Article
Times cited : (24)

References (33)
  • 1
    • 79955092142 scopus 로고    scopus 로고
    • The in vitro fidelity of yeast DNA polymerase δ and polymerase holoenzymes during dinucleotide microsatellite DNA synthesis
    • Abdulovic AL, Hile SE, Kunkel TA, Eckert KA. 2011. The in vitro fidelity of yeast DNA polymerase δ and polymerase holoenzymes during dinucleotide microsatellite DNA synthesis. DNA Repair 10: 497-505.
    • (2011) DNA Repair , vol.10 , pp. 497-505
    • Abdulovic, A.L.1    Hile, S.E.2    Kunkel, T.A.3    Eckert, K.A.4
  • 2
    • 0029144027 scopus 로고
    • Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain
    • Bebenek K, Beard WA, Casas-Finet JR, Kim H-R, Darden TA, Wilson SH, Kunkel TA. 1995. Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. J Biol Chem 270: 19516-19523.
    • (1995) J Biol Chem , vol.270 , pp. 19516-19523
    • Bebenek, K.1    Beard, W.A.2    Casas-Finet, J.R.3    Kim, H.-R.4    Darden, T.A.5    Wilson, S.H.6    Kunkel, T.A.7
  • 3
    • 0034437672 scopus 로고    scopus 로고
    • Streisinger Revisited: DNA Synthesis Errors Mediated by Substrate Misalignments. Cold Spring Harbor Symposia on Quant
    • Bebenek K, Kunkel T. 2000. Streisinger Revisited: DNA Synthesis Errors Mediated by Substrate Misalignments. Cold Spring Harbor Symposia on Quant. Biol 65: 81-92.
    • (2000) Biol , vol.65 , pp. 81-92
    • Bebenek, K.1    Kunkel, T.2
  • 5
    • 65249153186 scopus 로고    scopus 로고
    • Every microsatellite is different: Intrinsic DNA features dictate mutagenesis of common microsatellites present in the human genome
    • Eckert KA, Hile SE. 2009. Every microsatellite is different: Intrinsic DNA features dictate mutagenesis of common microsatellites present in the human genome. Mol Carcinogen 48: 379-388.
    • (2009) Mol Carcinogen , vol.48 , pp. 379-388
    • Eckert, K.A.1    Hile, S.E.2
  • 6
    • 0027491535 scopus 로고
    • Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase
    • Eckert KA, Kunkel T. 1993. Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase. J Biol Chem 268: 13462-13471.
    • (1993) J Biol Chem , vol.268 , pp. 13462-13471
    • Eckert, K.A.1    Kunkel, T.2
  • 7
    • 0030738503 scopus 로고    scopus 로고
    • Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions
    • Eckert KA, Hile S, Vargo P. 1997. Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions. Nucl Acids Res 25: 1450-1457.
    • (1997) Nucl Acids Res , vol.25 , pp. 1450-1457
    • Eckert, K.A.1    Hile, S.2    Vargo, P.3
  • 8
    • 0037143581 scopus 로고    scopus 로고
    • Misalignment-mediated DNA polymerase b mutations: Comparison of microsatellite and frame-shift error rates using a forward mutation assay
    • Eckert KA, Mowery A, Hile SE. 2002. Misalignment-mediated DNA polymerase b mutations: Comparison of microsatellite and frame-shift error rates using a forward mutation assay. Biochemistry 41: 10490-10498.
    • (2002) Biochemistry , vol.41 , pp. 10490-10498
    • Eckert, K.A.1    Mowery, A.2    Hile, S.E.3
  • 9
    • 3042782819 scopus 로고    scopus 로고
    • Microsatellites: Simple sequences with complex evolution
    • Ellegren H. 2004. Microsatellites: Simple sequences with complex evolution. Nat Rev Genet 5: 435-445.
    • (2004) Nat Rev Genet , vol.5 , pp. 435-445
    • Ellegren, H.1
  • 10
    • 33646490558 scopus 로고    scopus 로고
    • Mechanism of a genetic glissando*: Structural biology of indel mutations
    • Garcia-Diaz M, Kunkel T. 2006. Mechanism of a genetic glissando*: Structural biology of indel mutations. Trends Biochem Sci 31: 206-214.
    • (2006) Trends Biochem Sci , vol.31 , pp. 206-214
    • Garcia-Diaz, M.1    Kunkel, T.2
  • 11
    • 31044450194 scopus 로고    scopus 로고
    • Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
    • Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA. 2006. Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Cell 124: 331-342.
    • (2006) Cell , vol.124 , pp. 331-342
    • Garcia-Diaz, M.1    Bebenek, K.2    Krahn, J.M.3    Pedersen, L.C.4    Kunkel, T.A.5
  • 12
    • 0026769505 scopus 로고
    • Instability of simple sequence DNA in Saccharomyces cerevisiae
    • Henderson ST, Petes TD. 1992. Instability of simple sequence DNA in Saccharomyces cerevisiae. Mol Cell Biol 12: 2749-2757.
    • (1992) Mol Cell Biol , vol.12 , pp. 2749-2757
    • Henderson, S.T.1    Petes, T.D.2
  • 13
    • 1542606527 scopus 로고    scopus 로고
    • Positive correlation between DNA polymerase α-primase pausing and mutagenesis within polypyrimidine/polypurine microsatellite sequences
    • Hile SE, Eckert K. 2004. Positive correlation between DNA polymerase α-primase pausing and mutagenesis within polypyrimidine/polypurine microsatellite sequences. J Mol Biol 335: 745-759.
    • (2004) J Mol Biol , vol.335 , pp. 745-759
    • Hile, S.E.1    Eckert, K.2
  • 14
    • 39149094942 scopus 로고    scopus 로고
    • DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences
    • Hile SE, Eckert KA. 2008. DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. Nucleic Acids Res 36: 688-696.
    • (2008) Nucleic Acids Res , vol.36 , pp. 688-696
    • Hile, S.E.1    Eckert, K.A.2
  • 15
    • 84863280866 scopus 로고    scopus 로고
    • Beyond translesion synthesis: Polymerase K fidelity as a potential determinant of microsatellite stability
    • Hile SE, Wang X, Lee MYWT, Eckert KA. 2012. Beyond translesion synthesis: Polymerase K fidelity as a potential determinant of microsatellite stability. Nucleic Acids Res 40: 1636-1647.
    • (2012) Nucleic Acids Res , vol.40 , pp. 1636-1647
    • Hile, S.E.1    Wang, X.2    Lee, M.Y.W.T.3    Eckert, K.A.4
  • 16
    • 56649109929 scopus 로고    scopus 로고
    • The N-clasp of human DNA polymerase {kappa} promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions
    • Jia L, Geacintov NE, Broyde S. 2008. The N-clasp of human DNA polymerase {kappa} promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Nucl Acids Res 36: 6571-6584.
    • (2008) Nucl Acids Res , vol.36 , pp. 6571-6584
    • Jia, L.1    Geacintov, N.E.2    Broyde, S.3
  • 17
    • 0034635953 scopus 로고    scopus 로고
    • The human DINB1 gene encodes the DNA polymerase PolÎ
    • Johnson RE, Prakash S, Prakash L. 2000. The human DINB1 gene encodes the DNA polymerase PolÎ, Proc Natl Acad Sci 97: 3838.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 3838
    • Johnson, R.E.1    Prakash, S.2    Prakash, L.3
  • 18
    • 38049048656 scopus 로고    scopus 로고
    • The genome-wide determinants of human and chimpanzee microsatellite evolution
    • Kelkar YD, Tyekucheva S, Chiaromonte F, Makova KD. 2008. The genome-wide determinants of human and chimpanzee microsatellite evolution. Genome Res 18: 30-38.
    • (2008) Genome Res , vol.18 , pp. 30-38
    • Kelkar, Y.D.1    Tyekucheva, S.2    Chiaromonte, F.3    Makova, K.D.4
  • 19
    • 77958483312 scopus 로고    scopus 로고
    • What is a microsatellite: A computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats
    • Kelkar YD, Strubczewski N, Hile SE, Chiaromonte F, Eckert KA, Makova KD. 2010. What is a microsatellite: A computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats. Genome Biol Evol 2: 620.
    • (2010) Genome Biol Evol , vol.2 , pp. 620
    • Kelkar, Y.D.1    Strubczewski, N.2    Hile, S.E.3    Chiaromonte, F.4    Eckert, K.A.5    Makova, K.D.6
  • 21
    • 0021872030 scopus 로고
    • The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations
    • Kunkel T. 1985a. The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. J Biol Chem 260: 5787-5796.
    • (1985) J Biol Chem , vol.260 , pp. 5787-5796
    • Kunkel, T.1
  • 22
    • 0022344932 scopus 로고
    • The mutational specificity of DNA polymerases-alpha and-gamma during in vitro DNA synthesis
    • Kunkel TA. 1985b. The mutational specificity of DNA polymerases-alpha and-gamma during in vitro DNA synthesis. J Biol Chem 260: 12866-12874.
    • (1985) J Biol Chem , vol.260 , pp. 12866-12874
    • Kunkel, T.A.1
  • 23
    • 0025109103 scopus 로고
    • Misalignment-mediated DNA synthesis errors
    • Kunkel TA. 1990. Misalignment-mediated DNA synthesis errors. Biochemistry 29: 8003-8011.
    • (1990) Biochemistry , vol.29 , pp. 8003-8011
    • Kunkel, T.A.1
  • 26
    • 0035812849 scopus 로고    scopus 로고
    • Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication
    • Ling H, Boudsocq F, Woodgate R, Yang W. 2001. Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication. Cell 107: 91-102.
    • (2001) Cell , vol.107 , pp. 91-102
    • Ling, H.1    Boudsocq, F.2    Woodgate, R.3    Yang, W.4
  • 28
  • 29
    • 0034623139 scopus 로고    scopus 로고
    • Minor groove interactions at the DNA polymerase b active site modulate single-base deletion error rates
    • Osheroff WP, Beard WA, Yin S, Wilson SH, Kunkel TA. 2000. Minor groove interactions at the DNA polymerase b active site modulate single-base deletion error rates. J Biol Chem 275: 28033-28038.
    • (2000) J Biol Chem , vol.275 , pp. 28033-28038
    • Osheroff, W.P.1    Beard, W.A.2    Yin, S.3    Wilson, S.H.4    Kunkel, T.A.5
  • 30
    • 78650637385 scopus 로고    scopus 로고
    • Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases
    • Sherrer SM, Fiala KA, Fowler JD, Newmister SA, Pryor JM, Suo Z. 2011. Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases. Nucleic Acids Res 39: 609-622.
    • (2011) Nucleic Acids Res , vol.39 , pp. 609-622
    • Sherrer, S.M.1    Fiala, K.A.2    Fowler, J.D.3    Newmister, S.A.4    Pryor, J.M.5    Suo, Z.6
  • 33
    • 0037133339 scopus 로고    scopus 로고
    • Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini
    • Washington MT, Johnson RE, Prakash L, Prakash S. 2002. Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. Proc Natl Acad Sci 99: 1910.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 1910
    • Washington, M.T.1    Johnson, R.E.2    Prakash, L.3    Prakash, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.