-
2
-
-
4644264119
-
Endothelial dysfunction and damage in congestive heart failure: Relation of flow-mediated dilation to circulating endothelial cells, plasma indexes of endothelial damage, and brain natriuretic peptide
-
A.Y. Chong, A.D. Blann, J. Patel, B. Freestone, E. Hughes, and G.Y. Lip Endothelial dysfunction and damage in congestive heart failure: relation of flow-mediated dilation to circulating endothelial cells, plasma indexes of endothelial damage, and brain natriuretic peptide Circulation 110 2004 1794 1798
-
(2004)
Circulation
, vol.110
, pp. 1794-1798
-
-
Chong, A.Y.1
Blann, A.D.2
Patel, J.3
Freestone, B.4
Hughes, E.5
Lip, G.Y.6
-
3
-
-
42549153011
-
Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats
-
N. Kobayashi, T. Ohno, K. Yoshida, H. Fukushima, Y. Mamada, and M. Nomura Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats Am J Hypertens 21 2008 576 581
-
(2008)
Am J Hypertens
, vol.21
, pp. 576-581
-
-
Kobayashi, N.1
Ohno, T.2
Yoshida, K.3
Fukushima, H.4
Mamada, Y.5
Nomura, M.6
-
5
-
-
76749160244
-
Inhibition of dystrophin breakdown and endothelial nitric oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-Chloro-2-methylphenyl)-1- piperazinyl]ethyl]-5,6-dimethoxy-1- (4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) in left ventricular hypertrophied mice
-
F. Han, Y.M. Lu, H. Hasegawa, H. Kanai, E. Hachimura, and Y. Shirasaki Inhibition of dystrophin breakdown and endothelial nitric oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-Chloro-2-methylphenyl)-1- piperazinyl]ethyl]-5,6-dimethoxy-1- (4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) in left ventricular hypertrophied mice J Pharmacol Exp Ther 332 2010 421 428
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 421-428
-
-
Han, F.1
Lu, Y.M.2
Hasegawa, H.3
Kanai, H.4
Hachimura, E.5
Shirasaki, Y.6
-
6
-
-
20044363270
-
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
-
E. Takimoto, H.C. Champion, M. Li, D. Belardi, S. Ren, and E.R. Rodriguez Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy Nat Med 11 2005 214 222
-
(2005)
Nat Med
, vol.11
, pp. 214-222
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Belardi, D.4
Ren, S.5
Rodriguez, E.R.6
-
7
-
-
17844381569
-
Cardiac phosphodiesterase 5 (cGMP-specific) modulates β-adrenergic signaling in vivo and is down-regulated in heart failure
-
H. Senzaki, C.J. Smith, G.J. Juang, T. Isoda, S.P. Mayer, and A. Ohler Cardiac phosphodiesterase 5 (cGMP-specific) modulates β-adrenergic signaling in vivo and is down-regulated in heart failure FASEB J 15 2001 1718 1726
-
(2001)
FASEB J
, vol.15
, pp. 1718-1726
-
-
Senzaki, H.1
Smith, C.J.2
Juang, G.J.3
Isoda, T.4
Mayer, S.P.5
Ohler, A.6
-
8
-
-
33847689334
-
Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase
-
R.C. Kukreja Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase Br J Pharmacol 150 2007 538 540
-
(2007)
Br J Pharmacol
, vol.150
, pp. 538-540
-
-
Kukreja, R.C.1
-
9
-
-
41549085082
-
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice
-
F.N. Salloum, A. Abbate, A. Das, J.E. Houser, C.A. Mudrick, and I.Z. Qureshi Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice Am J Physiol Heart Circ Physiol 294 2008 H1398 H1406
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Salloum, F.N.1
Abbate, A.2
Das, A.3
Houser, J.E.4
Mudrick, C.A.5
Qureshi, I.Z.6
-
10
-
-
51249090123
-
The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells
-
J.W. Ramos The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells Int J Biochem Cell Biol 40 2008 2707 2719
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 2707-2719
-
-
Ramos, J.W.1
-
11
-
-
57649155045
-
Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta
-
A. Das, L. Xi, and R.C. Kukreja Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta J Biol Chem 283 2008 29572 29585
-
(2008)
J Biol Chem
, vol.283
, pp. 29572-29585
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
12
-
-
27344454845
-
KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases
-
B.N. Wu, H.F. Tu, D.G. Welsh, and I.J. Chen KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases Br J Pharmacol 146 2005 862 871
-
(2005)
Br J Pharmacol
, vol.146
, pp. 862-871
-
-
Wu, B.N.1
Tu, H.F.2
Welsh, D.G.3
Chen, I.J.4
-
13
-
-
33747593070
-
Inhibition of proinflammatory tumor necrosis factor-α-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2- chlorobenzene) piperazinyl]ethyl]-1,3- dimethyl xanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene) piperazinyl] ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G
-
B.N. Wu, C.W. Chen, S.F. Liou, J.L. Yeh, H.H. Chung, and I.J. Chen Inhibition of proinflammatory tumor necrosis factor-α-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2- chlorobenzene) piperazinyl]ethyl]-1,3- dimethyl xanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene) piperazinyl] ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: the involvement of soluble guanylate cyclase and protein kinase G Mol Pharmacol 70 2006 977 985
-
(2006)
Mol Pharmacol
, vol.70
, pp. 977-985
-
-
Wu, B.N.1
Chen, C.W.2
Liou, S.F.3
Yeh, J.L.4
Chung, H.H.5
Chen, I.J.6
-
14
-
-
77952836879
-
KMUP-1 inhibits acute and chronic pulmonary artery hypertension via eNOS-enhancement and cGMP-dependent inhibition of RhoA/Rho Kinase
-
H.H. Chung, Z.K. Dai, B.N. Wu, J.L. Yeh, C.Y. Chai, and K.S. Chu KMUP-1 inhibits acute and chronic pulmonary artery hypertension via eNOS-enhancement and cGMP-dependent inhibition of RhoA/Rho Kinase Br J Pharmacol 160 2010 971 986
-
(2010)
Br J Pharmacol
, vol.160
, pp. 971-986
-
-
Chung, H.H.1
Dai, Z.K.2
Wu, B.N.3
Yeh, J.L.4
Chai, C.Y.5
Chu, K.S.6
-
15
-
-
77949362015
-
KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways
-
J.L. Yeh, J.H. Hsu, P.J. Wu, S.F. Liou, C.P. Liu, and I.J. Chen KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways Br J Pharmacol 159 2010 1151 1160
-
(2010)
Br J Pharmacol
, vol.159
, pp. 1151-1160
-
-
Yeh, J.L.1
Hsu, J.H.2
Wu, P.J.3
Liou, S.F.4
Liu, C.P.5
Chen, I.J.6
-
16
-
-
19444372119
-
Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload
-
H. Ruetten, S. Dimmeler, D. Gehring, C. Ihling, and A.M. Zeiher Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload Cardiovasc Res 66 2005 444 453
-
(2005)
Cardiovasc Res
, vol.66
, pp. 444-453
-
-
Ruetten, H.1
Dimmeler, S.2
Gehring, D.3
Ihling, C.4
Zeiher, A.M.5
-
17
-
-
0036196099
-
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
-
I.N. Mungrue, R. Gros, X. You, A. Pirani, A. Azad, and T. Csont Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death J Clin Invest 109 2002 735 743
-
(2002)
J Clin Invest
, vol.109
, pp. 735-743
-
-
Mungrue, I.N.1
Gros, R.2
You, X.3
Pirani, A.4
Azad, A.5
Csont, T.6
-
18
-
-
14644417845
-
Putting the brake on cardiac hypertrophy: Exploiting the NO-cGMP counter-regulatory system
-
G.W. Booz Putting the brake on cardiac hypertrophy: exploiting the NO-cGMP counter-regulatory system Hypertension 45 2005 341 346
-
(2005)
Hypertension
, vol.45
, pp. 341-346
-
-
Booz, G.W.1
-
19
-
-
44349134115
-
Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency
-
M. Khairallah, R.J. Khairallah, M.E. Young, B.G. Allen, M.A. Gillis, and G. Danialou Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency Proc Natl Acad Sci U S A 105 2008 7028 7033
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7028-7033
-
-
Khairallah, M.1
Khairallah, R.J.2
Young, M.E.3
Allen, B.G.4
Gillis, M.A.5
Danialou, G.6
-
20
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
J.S. Beckman, and W.H. Koppenol Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly Am J Physiol 271 1996 C1424 C1437
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
21
-
-
19344375531
-
Reduction of diabetes-induced oxidative stress by phosphodiesterase inhibitors in rats
-
E. Milani, S. Nikfar, R. Khorasani, M.J. Zamani, and M. Abdollahi Reduction of diabetes-induced oxidative stress by phosphodiesterase inhibitors in rats Comp Biochem Physiol C Toxicol Pharmacol 140 2005 251 255
-
(2005)
Comp Biochem Physiol C Toxicol Pharmacol
, vol.140
, pp. 251-255
-
-
Milani, E.1
Nikfar, S.2
Khorasani, R.3
Zamani, M.J.4
Abdollahi, M.5
-
22
-
-
60549098432
-
Role of TNF-alpha in vascular dysfunction
-
H. Zhang, Y. Park, J. Wu, X. Chen, S. Lee, and J. Yang Role of TNF-alpha in vascular dysfunction Clin Sci 116 2009 219 230
-
(2009)
Clin Sci
, vol.116
, pp. 219-230
-
-
Zhang, H.1
Park, Y.2
Wu, J.3
Chen, X.4
Lee, S.5
Yang, J.6
-
24
-
-
0036843158
-
Involvement of extracellular signal regulated kinases 1/2 in cardiac hypertrophy and cell death
-
O.F. Bueno, and J.D. Molkentin Involvement of extracellular signal regulated kinases 1/2 in cardiac hypertrophy and cell death Circ Res 91 2002 776 781
-
(2002)
Circ Res
, vol.91
, pp. 776-781
-
-
Bueno, O.F.1
Molkentin, J.D.2
-
25
-
-
33751577221
-
Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: Co-operation with Src tyrosine kinase
-
K. Obasanjo-Blackshire, R. Mesquita, R.I. Jabr, J.D. Molkentin, S.L. Hart, and M.S. Marber Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: co-operation with Src tyrosine kinase Cardiovasc Res 71 2006 672 683
-
(2006)
Cardiovasc Res
, vol.71
, pp. 672-683
-
-
Obasanjo-Blackshire, K.1
Mesquita, R.2
Jabr, R.I.3
Molkentin, J.D.4
Hart, S.L.5
Marber, M.S.6
-
26
-
-
3242770551
-
2+-calcineurin-NFAT cascade in cardiac myocytes
-
2+-calcineurin-NFAT cascade in cardiac myocytes Cardiovasc Res 63 2004 450 457
-
(2004)
Cardiovasc Res
, vol.63
, pp. 450-457
-
-
Fiedler, B.1
Wollert, K.C.2
-
27
-
-
33847686720
-
Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat
-
G. Rossoni, B. Manfredi, V.De G. Colonna, M. Berti, M. Guazzi, and F. Berti Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat Br J Pharmacol 150 2007 567 576
-
(2007)
Br J Pharmacol
, vol.150
, pp. 567-576
-
-
Rossoni, G.1
Manfredi, B.2
Colonna, V.D.G.3
Berti, M.4
Guazzi, M.5
Berti, F.6
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