메뉴 건너뛰기




Volumn 3, Issue 5, 2012, Pages 255-266

Venous and arterial thrombotic risks with thalidomide: Evidence and practical guidance

Author keywords

aspirin; heparin; multiple myeloma; novel agents; thalidomide; thromboprophylaxis; venous thromboembolism; warfarin

Indexed keywords

ACETYLSALICYLIC ACID; BORTEZOMIB; CYCLOPHOSPHAMIDE; DABIGATRAN ETEXILATE; DALTEPARIN; DEXAMETHASONE; DOXORUBICIN; ENOXAPARIN; HEPARIN; MELPHALAN; PREDNISONE; RIVAROXABAN; THALIDOMIDE; WARFARIN;

EID: 84868653802     PISSN: 20420986     EISSN: 20420994     Source Type: Journal    
DOI: 10.1177/2042098612452291     Document Type: Review
Times cited : (46)

References (77)
  • 2
    • 84855498287 scopus 로고    scopus 로고
    • Prophylactic recombinant erythropoietin therapy and thalidomide are predictors of venous thromboembolism in patients with multiple myeloma: limited effectiveness of thromboprophylaxis
    • Anaissie E. Coleman E. Goodwin J. Kennedy R. Lockhart K. Stewart C. (2012) Prophylactic recombinant erythropoietin therapy and thalidomide are predictors of venous thromboembolism in patients with multiple myeloma: limited effectiveness of thromboprophylaxis. Cancer 118: 549–557.
    • (2012) Cancer , vol.118 , pp. 549-557
    • Anaissie, E.1    Coleman, E.2    Goodwin, J.3    Kennedy, R.4    Lockhart, K.5    Stewart, C.6
  • 3
    • 28844472902 scopus 로고    scopus 로고
    • Lenalidomide and thalidomide: mechanisms of action–similarities and differences
    • Suppl. 4)
    • Anderson K. (2005) Lenalidomide and thalidomide: mechanisms of action–similarities and differences. Semin Hematol 42(4 Suppl. 4): S3–S8.
    • (2005) Semin Hematol , vol.42 , Issue.4 , pp. S3-S8
    • Anderson, K.1
  • 4
    • 45949103309 scopus 로고    scopus 로고
    • Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence- Based Clinical Practice Guidelines (8th Edition)
    • Ansell J. Hirsh J. Hylek E. Jacobson A. Crowther M. Palareti G. (2008) Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence- Based Clinical Practice Guidelines (8th Edition). Chest 133: 160S–198S.
    • (2008) Chest , vol.133 , pp. 160S-198S
    • Ansell, J.1    Hirsh, J.2    Hylek, E.3    Jacobson, A.4    Crowther, M.5    Palareti, G.6
  • 5
    • 0035880229 scopus 로고    scopus 로고
    • Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
    • Barlogie B. Desikan R. Eddlemon P. Spencer T. Zeldis J. Munshi N. (2001) Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood 98: 492–494.
    • (2001) Blood , vol.98 , pp. 492-494
    • Barlogie, B.1    Desikan, R.2    Eddlemon, P.3    Spencer, T.4    Zeldis, J.5    Munshi, N.6
  • 7
    • 34547772153 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes
    • Bassand J. Hamm C. Ardissino D. Boersma E. Budaj A. Fernández-Avilés F. (2007) Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Eur Heart J 28: 1598–1660.
    • (2007) Eur Heart J , vol.28 , pp. 1598-1660
    • Bassand, J.1    Hamm, C.2    Ardissino, D.3    Boersma, E.4    Budaj, A.5    Fernández-Avilés, F.6
  • 8
    • 0035806950 scopus 로고    scopus 로고
    • The thrombophilias: well-defined risk factors with uncertain therapeutic implications
    • Bauer K. (2001) The thrombophilias: well-defined risk factors with uncertain therapeutic implications. Ann Intern Med 135: 367–373.
    • (2001) Ann Intern Med , vol.135 , pp. 367-373
    • Bauer, K.1
  • 9
    • 28544436819 scopus 로고    scopus 로고
    • The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma
    • Baz R. Li L. Kottke-Marchant K. Srkalovic G. McGowan B. Yiannaki E. (2005) The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma. Mayo Clin Proc 80: 1568–1574
    • (2005) Mayo Clin Proc , vol.80 , pp. 1568-1574
    • Baz, R.1    Li, L.2    Kottke-Marchant, K.3    Srkalovic, G.4    McGowan, B.5    Yiannaki, E.6
  • 10
    • 78650159700 scopus 로고    scopus 로고
    • Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: results of a randomized trial from the Turkish Myeloma Study Group
    • Beksac M. Haznedar R. Firatli-Tuglular T. Ozdogu H. Aydogdu I. Konuk N. (2011) Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: results of a randomized trial from the Turkish Myeloma Study Group. Eur J Haematol 86: 16–22.
    • (2011) Eur J Haematol , vol.86 , pp. 16-22
    • Beksac, M.1    Haznedar, R.2    Firatli-Tuglular, T.3    Ozdogu, H.4    Aydogdu, I.5    Konuk, N.6
  • 11
    • 0037775639 scopus 로고    scopus 로고
    • Cancer-associated thrombosis
    • Bick R. (2003) Cancer-associated thrombosis. N Engl J Med 349: 109–111.
    • (2003) N Engl J Med , vol.349 , pp. 109-111
    • Bick, R.1
  • 12
    • 13444256137 scopus 로고    scopus 로고
    • Malignancy, prothrombotic mutations, and the risk of venous thrombosis
    • Blom J. Doggen C. Osanto S. Rosendaal F. (2005) Malignancy, prothrombotic mutations, and the risk of venous thrombosis. JAMA 293: 715–722.
    • (2005) JAMA , vol.293 , pp. 715-722
    • Blom, J.1    Doggen, C.2    Osanto, S.3    Rosendaal, F.4
  • 13
    • 0142182561 scopus 로고    scopus 로고
    • Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism
    • Buller H. Davidson B. Decousus H. Gallus A. Gent M. Piovella F. (2003) Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. N Engl J Med 349: 1695–1702.
    • (2003) N Engl J Med , vol.349 , pp. 1695-1702
    • Buller, H.1    Davidson, B.2    Decousus, H.3    Gallus, A.4    Gent, M.5    Piovella, F.6
  • 14
    • 2542424669 scopus 로고    scopus 로고
    • Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: A randomized trial
    • Buller H. Davidson B. Decousus H. Gallus A. Gent M. Piovella F. (2004) Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: A randomized trial. Ann Intern Med 140: 867–873.
    • (2004) Ann Intern Med , vol.140 , pp. 867-873
    • Buller, H.1    Davidson, B.2    Decousus, H.3    Gallus, A.4    Gent, M.5    Piovella, F.6
  • 15
    • 0028044016 scopus 로고
    • Antiplatelet treatment for thromboprophylaxis: a step forward or backwards?
    • Cohen A. Skinner J. Kakkar V. (1994) Antiplatelet treatment for thromboprophylaxis: a step forward or backwards? BMJ 309: 1213–1215.
    • (1994) BMJ , vol.309 , pp. 1213-1215
    • Cohen, A.1    Skinner, J.2    Kakkar, V.3
  • 16
    • 4444308010 scopus 로고    scopus 로고
    • Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone
    • Corso A. Lorenzi A. Terulla V. Airò F. Varettoni M. Mangiacavalli S. (2004) Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone. Ann Hematol 83: 588–591.
    • (2004) Ann Hematol , vol.83 , pp. 588-591
    • Corso, A.1    Lorenzi, A.2    Terulla, V.3    Airò, F.4    Varettoni, M.5    Mangiacavalli, S.6
  • 17
    • 33644533213 scopus 로고    scopus 로고
    • Primary treatment with pulsed melphalan, dexamethasone and thalidomide for elderly symptomatic patients with multiple myeloma
    • Dimopoulos M. Anagnostopoulos A. Terpos E. Repoussis P. Zomas A. Katodritou E. (2006) Primary treatment with pulsed melphalan, dexamethasone and thalidomide for elderly symptomatic patients with multiple myeloma. Haematologica 91: 252–254.
    • (2006) Haematologica , vol.91 , pp. 252-254
    • Dimopoulos, M.1    Anagnostopoulos, A.2    Terpos, E.3    Repoussis, P.4    Zomas, A.5    Katodritou, E.6
  • 18
    • 0642276742 scopus 로고    scopus 로고
    • Treatment of plasma cell dyscrasias with thalidomide and its derivates
    • Dimopoulos M. Anagnostopoulos A. Weber D. (2003) Treatment of plasma cell dyscrasias with thalidomide and its derivates. J Clin Oncol 21: 4444–4454.
    • (2003) J Clin Oncol , vol.21 , pp. 4444-4454
    • Dimopoulos, M.1    Anagnostopoulos, A.2    Weber, D.3
  • 19
    • 11144356289 scopus 로고    scopus 로고
    • Pulsed cyclophosphamide, thalidomide and dexamethasone: an oral regimen for previously treated patients with multiple myeloma
    • Dimopoulos M. Hamilos G. Zomas A. Gika D. Efstathiou E. Grigoraki V. (2004) Pulsed cyclophosphamide, thalidomide and dexamethasone: an oral regimen for previously treated patients with multiple myeloma. Hematol J 5: 112–117.
    • (2004) Hematol J , vol.5 , pp. 112-117
    • Dimopoulos, M.1    Hamilos, G.2    Zomas, A.3    Gika, D.4    Efstathiou, E.5    Grigoraki, V.6
  • 20
  • 21
    • 9444227297 scopus 로고    scopus 로고
    • Hemostatic complications associated with paraproteinemias
    • Eby C. Blinder M. (2003) Hemostatic complications associated with paraproteinemias. Curr Hematol Rep 2: 388–394.
    • (2003) Curr Hematol Rep , vol.2 , pp. 388-394
    • Eby, C.1    Blinder, M.2
  • 22
    • 34848833957 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial
    • Facon T. Mary J. Hulin C. Benboubker L. Attal M. Pegourie B. (2007) Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet 370: 1209–1218.
    • (2007) Lancet , vol.370 , pp. 1209-1218
    • Facon, T.1    Mary, J.2    Hulin, C.3    Benboubker, L.4    Attal, M.5    Pegourie, B.6
  • 23
    • 84993733117 scopus 로고    scopus 로고
    • Questions and Answers on Medication Guides for Erythropoiesis-Stimulating Agents (ESAs)
    • Accessed 12 December 2011, at
    • FDA (2010) Questions and Answers on Medication Guides for Erythropoiesis-Stimulating Agents (ESAs). Accessed 12 December 2011, at http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm109380.htm.
    • (2010)
  • 24
    • 23744449806 scopus 로고    scopus 로고
    • The relationship between inflammation and venous thrombosis. A systematic review of clinical studies
    • Fox E. Kahn S. (2005) The relationship between inflammation and venous thrombosis. A systematic review of clinical studies. Thromb Haemost 94: 362–365.
    • (2005) Thromb Haemost , vol.94 , pp. 362-365
    • Fox, E.1    Kahn, S.2
  • 25
    • 77952304296 scopus 로고    scopus 로고
    • New oral anticoagulants for thromboprophylaxis after total hip or knee arthroplasty
    • Friedman R. (2009) New oral anticoagulants for thromboprophylaxis after total hip or knee arthroplasty. Orthopedics 32: 79–84.
    • (2009) Orthopedics , vol.32 , pp. 79-84
    • Friedman, R.1
  • 26
    • 24944513945 scopus 로고    scopus 로고
    • Atherothrombosis and high-risk plaque: part I: evolving concepts
    • Fuster V. Moreno P. Fayad Z. Corti R. Badimon J. (2005) Atherothrombosis and high-risk plaque: part I: evolving concepts. J Am Coll Cardiol 46: 937–954.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 937-954
    • Fuster, V.1    Moreno, P.2    Fayad, Z.3    Corti, R.4    Badimon, J.5
  • 27
    • 1942522741 scopus 로고    scopus 로고
    • The oral combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is effective in relapsed/refractory multiple myeloma
    • García-Sanz R. González-Porras J. Hernández J. Polo-Zarzuela M. Sureda A. Barrenetxea C. (2004) The oral combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is effective in relapsed/refractory multiple myeloma. Leukemia 18: 856–63.
    • (2004) Leukemia , vol.18 , pp. 856-863
    • García-Sanz, R.1    González-Porras, J.2    Hernández, J.3    Polo-Zarzuela, M.4    Sureda, A.5    Barrenetxea, C.6
  • 29
    • 0033535363 scopus 로고    scopus 로고
    • Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based cohort study
    • Heit J. Silverstein M. Mohr D. Petterson T. O–Fallon W. Melton L. (1999) Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based cohort study. Arch Intern Med 159: 445–453.
    • (1999) Arch Intern Med , vol.159 , pp. 445-453
    • Heit, J.1    Silverstein, M.2    Mohr, D.3    Petterson, T.4    O–Fallon, W.5    Melton, L.6
  • 31
    • 23244458669 scopus 로고    scopus 로고
    • Combined thalidomide and cyclophosphamide treatment for refractory or relapsed multiple myeloma patients: a prospective phase II study
    • Hovenga S. Daenen S. de Wolf J. van Imhoff G. Kluin-Nelemans H. Sluiter W. (2005) Combined thalidomide and cyclophosphamide treatment for refractory or relapsed multiple myeloma patients: a prospective phase II study. Ann Hematol 84: 311–316.
    • (2005) Ann Hematol , vol.84 , pp. 311-316
    • Hovenga, S.1    Daenen, S.2    de Wolf, J.3    van Imhoff, G.4    Kluin-Nelemans, H.5    Sluiter, W.6
  • 32
    • 33745269206 scopus 로고    scopus 로고
    • Aspirin in the prevention and treatment of venous thromboembolism
    • Hovens M. Snoep J. Tamsma J. Huisman M. (2006) Aspirin in the prevention and treatment of venous thromboembolism. J Thromb Haemost 4: 1470–1475.
    • (2006) J Thromb Haemost , vol.4 , pp. 1470-1475
    • Hovens, M.1    Snoep, J.2    Tamsma, J.3    Huisman, M.4
  • 33
    • 68949137225 scopus 로고    scopus 로고
    • Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial
    • Hulin C. Facon T. Rodon P. Pegourie B. Benboubker L. Doyen C. (2009) Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial. J Clin Oncol 27: 3664–3670.
    • (2009) J Clin Oncol , vol.27 , pp. 3664-3670
    • Hulin, C.1    Facon, T.2    Rodon, P.3    Pegourie, B.4    Benboubker, L.5    Doyen, C.6
  • 34
    • 4644316831 scopus 로고    scopus 로고
    • Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology
    • Kaushal V. Kaushal G. Melkaveri S. Mehta P. (2004) Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology. J Thromb Haemost 2: 327–334.
    • (2004) J Thromb Haemost , vol.2 , pp. 327-334
    • Kaushal, V.1    Kaushal, G.2    Melkaveri, S.3    Mehta, P.4
  • 36
    • 0042161862 scopus 로고    scopus 로고
    • Hyperfractionated cyclophosphamide in combination with pulsed dexamethasone and thalidomide (HyperCDT) in primary refractory or relapsed multiple myeloma
    • Kropff M. Lang N. Bisping G. Dominé N. Innig G. Hentrich M. (2003) Hyperfractionated cyclophosphamide in combination with pulsed dexamethasone and thalidomide (HyperCDT) in primary refractory or relapsed multiple myeloma. Br J Haematol 122: 607–616.
    • (2003) Br J Haematol , vol.122 , pp. 607-616
    • Kropff, M.1    Lang, N.2    Bisping, G.3    Dominé, N.4    Innig, G.5    Hentrich, M.6
  • 37
    • 0037216068 scopus 로고    scopus 로고
    • Response rate, durability of response, and survival after thalidomide therapy for relapsed multiple myeloma
    • Kumar S. Gertz M. Dispenzieri A. Lacy M. Geyer S. Iturria N. (2003) Response rate, durability of response, and survival after thalidomide therapy for relapsed multiple myeloma. Mayo Clin Proc 78: 34–39.
    • (2003) Mayo Clin Proc , vol.78 , pp. 34-39
    • Kumar, S.1    Gertz, M.2    Dispenzieri, A.3    Lacy, M.4    Geyer, S.5    Iturria, N.6
  • 38
    • 21344459018 scopus 로고    scopus 로고
    • Low-dose thalidomide in combination with oral weekly cyclophosphamide and pulsed dexamethasone is a well tolerated and effective regimen in patients with relapsed and refractory multiple myeloma
    • Kyriakou C. Thomson K. D–Sa S. Flory A. Hanslip J. Goldstone A. (2005) Low-dose thalidomide in combination with oral weekly cyclophosphamide and pulsed dexamethasone is a well tolerated and effective regimen in patients with relapsed and refractory multiple myeloma. Br J Haematol 129: 763–770.
    • (2005) Br J Haematol , vol.129 , pp. 763-770
    • Kyriakou, C.1    Thomson, K.2    D–Sa, S.3    Flory, A.4    Hanslip, J.5    Goldstone, A.6
  • 39
    • 77956515604 scopus 로고    scopus 로고
    • Arterial thrombosis complicates myeloma
    • Lacy M. (2010) Arterial thrombosis complicates myeloma. Blood 116: 2–3.
    • (2010) Blood , vol.116 , pp. 2-3
    • Lacy, M.1
  • 40
    • 0027257511 scopus 로고
    • Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention
    • Landefeld C. Beyth R. (1993) Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am J Med 95: 315–328.
    • (1993) Am J Med , vol.95 , pp. 315-328
    • Landefeld, C.1    Beyth, R.2
  • 41
    • 77649126524 scopus 로고    scopus 로고
    • Heart disease and stroke statistics–2010 update: a report from the American Heart Association
    • Lloyd-Jones D. Adams R. Brown T. Carnethon M. Dai S. De Simone G. (2010) Heart disease and stroke statistics–2010 update: a report from the American Heart Association. Circulation 121: e46–e215.
    • (2010) Circulation , vol.121 , pp. e46-e215
    • Lloyd-Jones, D.1    Adams, R.2    Brown, T.3    Carnethon, M.4    Dai, S.5    De Simone, G.6
  • 42
    • 36849070772 scopus 로고    scopus 로고
    • American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer
    • Lyman G.H. Khorana A.A. Falanga A. Clarke-Pearson D. Flowers C. Jahanzeb M. (2007) American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J Clin Oncol 25: 5490–5505.
    • (2007) J Clin Oncol , vol.25 , pp. 5490-5505
    • Lyman, G.H.1    Khorana, A.A.2    Falanga, A.3    Clarke-Pearson, D.4    Flowers, C.5    Jahanzeb, M.6
  • 43
    • 0036846653 scopus 로고    scopus 로고
    • Dose-dependent effect of thalidomide on overall survival in relapsed multiple myeloma
    • Neben K. Moehler T. Benner A. Kraemer A. Egerer G. Ho A. (2002) Dose-dependent effect of thalidomide on overall survival in relapsed multiple myeloma. Clin Cancer Res 8: 3377–3382.
    • (2002) Clin Cancer Res , vol.8 , pp. 3377-3382
    • Neben, K.1    Moehler, T.2    Benner, A.3    Kraemer, A.4    Egerer, G.5    Ho, A.6
  • 44
    • 77649139818 scopus 로고    scopus 로고
    • Complications of multiple myeloma therapy, part 2: risk reduction and management of venous thromboembolism, osteonecrosis of the jaw, renal complications, and anemia
    • Niesvizky R. Badros A. (2010) Complications of multiple myeloma therapy, part 2: risk reduction and management of venous thromboembolism, osteonecrosis of the jaw, renal complications, and anemia. J Natl Compr Canc Netw 8: S13–S20.
    • (2010) J Natl Compr Canc Netw , vol.8 , pp. S13-S20
    • Niesvizky, R.1    Badros, A.2
  • 45
    • 37149054965 scopus 로고    scopus 로고
    • Prophylactic low-dose aspirin is effective antithrombotic therapy for combination treatments of thalidomide or lenalidomide in myeloma
    • Niesvizky R. Martínez-Baños D. Jalbrzikowski J. Christos P. Furst J. De Sancho M. (2007) Prophylactic low-dose aspirin is effective antithrombotic therapy for combination treatments of thalidomide or lenalidomide in myeloma. Leuk Lymphoma 48: 2330–2337.
    • (2007) Leuk Lymphoma , vol.48 , pp. 2330-2337
    • Niesvizky, R.1    Martínez-Baños, D.2    Jalbrzikowski, J.3    Christos, P.4    Furst, J.5    De Sancho, M.6
  • 46
    • 0035927983 scopus 로고    scopus 로고
    • Deep venous thrombosis and thalidomide therapy for multiple myeloma
    • Osman K. Comenzo R. Rajkumar S. (2001) Deep venous thrombosis and thalidomide therapy for multiple myeloma. N Engl J Med 344: 1951–1952.
    • (2001) N Engl J Med , vol.344 , pp. 1951-1952
    • Osman, K.1    Comenzo, R.2    Rajkumar, S.3
  • 47
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial
    • Palumbo A. Bringhen S. Caravita T. Merla E. Capparella V. Callea V. (2006) Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet 367: 825–831.
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3    Merla, E.4    Capparella, V.5    Callea, V.6
  • 48
    • 78650993336 scopus 로고    scopus 로고
    • Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: a randomized controlled trial
    • Palumbo A. Bringhen S. Rossi D. Cavalli M. Larocca A. Ria R. (2010) Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: a randomized controlled trial. J Clin Oncol 28: 5101–5109.
    • (2010) J Clin Oncol , vol.28 , pp. 5101-5109
    • Palumbo, A.1    Bringhen, S.2    Rossi, D.3    Cavalli, M.4    Larocca, A.5    Ria, R.6
  • 49
    • 79952752535 scopus 로고    scopus 로고
    • Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial
    • Palumbo A. Cavo M. Bringhen S. Zamagni E. Romano A. Patriarca F. (2011) Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial. J Clin Oncol 29: 986–993.
    • (2011) J Clin Oncol , vol.29 , pp. 986-993
    • Palumbo, A.1    Cavo, M.2    Bringhen, S.3    Zamagni, E.4    Romano, A.5    Patriarca, F.6
  • 50
    • 43249097561 scopus 로고    scopus 로고
    • Thalidomide for treatment of multiple myeloma: 10 years later
    • Palumbo A. Facon T. Sonneveld P. Bladè J. Offidani M. Gay F. (2008a) Thalidomide for treatment of multiple myeloma: 10 years later. Blood 111: 3968–3977.
    • (2008) Blood , vol.111 , pp. 3968-3977
    • Palumbo, A.1    Facon, T.2    Sonneveld, P.3    Bladè, J.4    Offidani, M.5    Gay, F.6
  • 53
    • 0034655567 scopus 로고    scopus 로고
    • Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial
    • Pulmonary Embolism Prevention (PEP) Trial Collaborative Group (2000) Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet 355: 1295–1302.
    • (2000) Lancet , vol.355 , pp. 1295-1302
  • 54
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar S. Blood E. Vesole D. Fonseca R. Greipp P. (2006) Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol 24: 431–436.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.1    Blood, E.2    Vesole, D.3    Fonseca, R.4    Greipp, P.5
  • 56
    • 39749191084 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Rosamond W. Flegal K. Furie K. Go A. Greenlund K. Haase N. (2008) Heart disease and stroke statistics - 2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117: e25–e146.
    • (2008) Circulation , vol.117 , pp. e25-e146
    • Rosamond, W.1    Flegal, K.2    Furie, K.3    Go, A.4    Greenlund, K.5    Haase, N.6
  • 57
    • 0034639246 scopus 로고    scopus 로고
    • An epidemiologic study of risk factors for deep vein thrombosis in medical outpatients: the Sirius study
    • Samama M. (2000) An epidemiologic study of risk factors for deep vein thrombosis in medical outpatients: the Sirius study. Arch Intern Med 160: 3415–3420.
    • (2000) Arch Intern Med , vol.160 , pp. 3415-3420
    • Samama, M.1
  • 59
    • 33745749976 scopus 로고    scopus 로고
    • Combination chemotherapy with cyclophosphamide, thalidomide and dexamethasone for patients with refractory, newly diagnosed or relapsed myeloma
    • Sidra G. Williams C. Russell N. Zaman S. Myers B. Byrne J. (2006) Combination chemotherapy with cyclophosphamide, thalidomide and dexamethasone for patients with refractory, newly diagnosed or relapsed myeloma. Haematologica 91: 862–863.
    • (2006) Haematologica , vol.91 , pp. 862-863
    • Sidra, G.1    Williams, C.2    Russell, N.3    Zaman, S.4    Myers, B.5    Byrne, J.6
  • 60
    • 0032559775 scopus 로고    scopus 로고
    • Trends in the incidence of deep vein thrombosis and pulmonary embolism. A 25-year population-based study
    • Silverstein M. Heit J. Mohr D. Petterson T. O–Fallon W. Melton L. (1998) Trends in the incidence of deep vein thrombosis and pulmonary embolism. A 25-year population-based study. Arch Intern Med 158: 585–593.
    • (1998) Arch Intern Med , vol.158 , pp. 585-593
    • Silverstein, M.1    Heit, J.2    Mohr, D.3    Petterson, T.4    O–Fallon, W.5    Melton, L.6
  • 62
    • 3242778603 scopus 로고    scopus 로고
    • Monoclonal gammopathy of undetermined significance and multiple myeloma are associated with an increased incidence of venothromboembolic disease
    • Srkalovic G. Cameron M. Rybicki L. Deitcher S. Kattke-Marchant K. Hussein M. (2004) Monoclonal gammopathy of undetermined significance and multiple myeloma are associated with an increased incidence of venothromboembolic disease. Cancer 101: 558–566.
    • (2004) Cancer , vol.101 , pp. 558-566
    • Srkalovic, G.1    Cameron, M.2    Rybicki, L.3    Deitcher, S.4    Kattke-Marchant, K.5    Hussein, M.6
  • 63
    • 16244363678 scopus 로고    scopus 로고
    • Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immunomodulatory agent Actimid (CC-4047) and their relationship with venous thrombosis
    • Streetly M. Hunt B. Parmar K. Jones R. Zeldis J. Schey S. (2005) Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immunomodulatory agent Actimid (CC-4047) and their relationship with venous thrombosis. Eur J Haematol 74: 293–296.
    • (2005) Eur J Haematol , vol.74 , pp. 293-296
    • Streetly, M.1    Hunt, B.2    Parmar, K.3    Jones, R.4    Zeldis, J.5    Schey, S.6
  • 64
    • 27644591608 scopus 로고    scopus 로고
    • Properties of thalidomide and its analogues: implications for anticancer therapy
    • Teo S. (2005) Properties of thalidomide and its analogues: implications for anticancer therapy. AAPS J 7: E14–E19.
    • (2005) AAPS J , vol.7 , pp. E14-E19
    • Teo, S.1
  • 65
    • 0034905077 scopus 로고    scopus 로고
    • The revitalization of thalidomide
    • Thomas D. Kantarjian H. (2001) The revitalization of thalidomide. Ann Oncol 12: 885–886.
    • (2001) Ann Oncol , vol.12 , pp. 885-886
    • Thomas, D.1    Kantarjian, H.2
  • 66
    • 0029758257 scopus 로고    scopus 로고
    • Rediscovering thalidomide: a review of its mechanism of action, side effects, and potential uses
    • Tseng S. Pak G. Washenik K. Pomeranz M. Shupack J. (1996) Rediscovering thalidomide: a review of its mechanism of action, side effects, and potential uses. J Am Acad Dermatol 35: 969–979.
    • (1996) J Am Acad Dermatol , vol.35 , pp. 969-979
    • Tseng, S.1    Pak, G.2    Washenik, K.3    Pomeranz, M.4    Shupack, J.5
  • 68
    • 77956599686 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma
    • Waage A. Gimsing P. Fayers P. Abildgaard N. Ahlberg L. Björkstrand B. (2010) Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma. Blood 116: 1405–1412.
    • (2010) Blood , vol.116 , pp. 1405-1412
    • Waage, A.1    Gimsing, P.2    Fayers, P.3    Abildgaard, N.4    Ahlberg, L.5    Björkstrand, B.6
  • 69
    • 0142117347 scopus 로고    scopus 로고
    • Thalidomide and its derivatives: new promise for multiple myeloma
    • Weber D. (2003) Thalidomide and its derivatives: new promise for multiple myeloma. Cancer Control 10: 375–83.
    • (2003) Cancer Control , vol.10 , pp. 375-383
    • Weber, D.1
  • 70
    • 0037208595 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for previously untreated multiple myeloma
    • Weber D. Rankin K. Gavino M. Delasalle K. Alexanian R. (2003) Thalidomide alone or with dexamethasone for previously untreated multiple myeloma. J Clin Oncol 21: 16–19.
    • (2003) J Clin Oncol , vol.21 , pp. 16-19
    • Weber, D.1    Rankin, K.2    Gavino, M.3    Delasalle, K.4    Alexanian, R.5
  • 71
    • 0141651863 scopus 로고    scopus 로고
    • Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures
    • White R. Zhou H. Romano P. (2003) Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost 90: 446–455.
    • (2003) Thromb Haemost , vol.90 , pp. 446-455
    • White, R.1    Zhou, H.2    Romano, P.3
  • 72
    • 77955495783 scopus 로고    scopus 로고
    • Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study
    • Wijermans P. Schaafsma M. Termorshuizen F. Ammerlaan R. Wittebol S. Sinnige H. (2010) Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study. J Clin Oncol 28: 3160–3166.
    • (2010) J Clin Oncol , vol.28 , pp. 3160-3166
    • Wijermans, P.1    Schaafsma, M.2    Termorshuizen, F.3    Ammerlaan, R.4    Wittebol, S.5    Sinnige, H.6
  • 73
    • 0036380265 scopus 로고    scopus 로고
    • Thalidomide in patients with advanced multiple myeloma: a study of 83 patients – report of the Intergroupe Francophone du Myelome (IFM)
    • Yakoub-Agha I. Attal M. Dumontet C. Delannoy V. Moreau P. Berthou C. (2002) Thalidomide in patients with advanced multiple myeloma: a study of 83 patients – report of the Intergroupe Francophone du Myelome (IFM). Hematol J 3: 185–192.
    • (2002) Hematol J , vol.3 , pp. 185-192
    • Yakoub-Agha, I.1    Attal, M.2    Dumontet, C.3    Delannoy, V.4    Moreau, P.5    Berthou, C.6
  • 74
    • 4544332965 scopus 로고    scopus 로고
    • Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation
    • Zangari M. Barlogie B. Anaissie E. Saghafifar F. Eddlemon P. Jacobson J. (2004) Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation. Br J Haematol 126: 715–721.
    • (2004) Br J Haematol , vol.126 , pp. 715-721
    • Zangari, M.1    Barlogie, B.2    Anaissie, E.3    Saghafifar, F.4    Eddlemon, P.5    Jacobson, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.