Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy

Circulation: Cardiovascular Genetics

Volumn 5, Issue 5, 2012, Pages 503-510

  Lakdawala, Neal K ^a   Thune, Jens J ^b   Colan, Steven D ^c   Cirino, Allison L ^a   Farrohi, Faranak ^a   Rivero, Jose ^a   McDonough, Barbara ^d   Sparks, Elizabeth ^d   Orav, E J ^a   Seidman, J G ^d   Seidman, Christine E ^a,d,e   Ho, Carolyn Y ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Rigshospitalet   (Denmark)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Contractility; Dilated cardiomyopathy; Echocardiography; Hypertrophic cardiomyopathy; Sarcomere

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; FEMALE; GENE MUTATION; HEART MUSCLE CONTRACTILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SARCOMERE; SYSTOLIC DYSFUNCTION;

ADOLESCENT; ADULT; AGED; CARDIOMYOPATHY, DILATED; CARDIOMYOPATHY, HYPERTROPHIC; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; ECHOCARDIOGRAPHY; FEMALE; GENOTYPE; HEART RATE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; PHENOTYPE; SARCOMERES; VENTRICULAR FUNCTION, LEFT; YOUNG ADULT;

EID: 84868626402     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.112.962761     Document Type: Article

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