Changes on D2-like receptor induced Gi protein activation and hippocampal dopamine release in kindled rats

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 40, Issue 1, 2013, Pages 246-251

  Alcantara Gonzalez, David ^a   Floran, Benjamin ^a   Escartin, Erik ^a   Rocha, Luisa ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

D2 like receptors; Dopamine; Gi protein; Hippocampus; Kindling

Indexed keywords

DOPAMINE 2 RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE 5' O (3 THIOTRIPHOSPHATE) S 35; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; SULFUR 35; SULPIRIDE; UNCLASSIFIED DRUG;

AFTERDISCHARGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN FUNCTION; CONTROLLED STUDY; DISEASE DURATION; DOPAMINE RELEASE; ELECTROENCEPHALOGRAM; ENZYME ACTIVATION; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SEIZURE;

ANIMALS; DOPAMINE; DOPAMINE ANTAGONISTS; ELECTRIC STIMULATION; HIPPOCAMPUS; KINDLING, NEUROLOGIC; MALE; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; SULPIRIDE; SYNAPTIC TRANSMISSION;

EID: 84868599341     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2012.10.007     Document Type: Article

References (48)

1. Al-Tajir G., Starr M.S. D-2 agonists protect rodents against pilocarpine induced convulsions by stimulating D-2 receptors in the striatum, but not in the substantia nigra. Pharmacol Biochem Behav 1991, 39:109-113.
2. Ando N., Morimoto K., Watanabe T., Ninomiya T., Suwaki H. Enhancement of central dopaminergic activity in the kainate model of temporal lobe epilepsy: implication for the mechanism of epileptic psychosis. Neuropsychopharmacology 2004, 29:1251-1258.
3. Baulac M., Verney C., Berger B. Dopaminergic innervation of the parahippocampal and hippocampal regions in the rat. Rev Neurol (Paris) 1986, 142:895-905.
4. Beazely M.A., Tong A., Wei W.L., Van Tol H., Sidhu B., MacDonald J.F. D2-class dopamine receptor inhibition of NMDA currents in prefrontal cortical neurons is platelet-derived growth factor receptor-dependent. J Neurochem 2006, 98:1657-1663.
5. 2+-activated potassium conductance in mammalian hippocampal pyramidal cells. Nature 1982, 297:76-79.
6. Bourne J.A., Fosbraey P., Halliday J. Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists. Eur J Pharmacol 2001, 413:189-198.
7. Clinckers R., Smolders I., Meurs A., Ebinger G., Michotte Y. Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D2 and 5-HT1A receptors. J Neurochem 2004, 89:834-843.
8. Clinckers R., Gheuens S., Smolders I., Meurs A., Ebinger G., Michotte Y. In vivo modulatory action of extracellular glutamate on the anticonvulsant effects of hippocampal dopamine. Epilepsia 2005, 46:828-836.
9. Csernansky J.G., Kerr S., Pruthi R., Prosser E.S. Mesolimbic dopamine receptor increases two weeks following hippocampal kindling. Brain Res 1988, 449:357-360.
10. Csernansky J.G., Mellentin J., Beauclair L., Lombrozo L. Mesolimbic dopaminergic supersensitivity following electrical kindling of the amygdala. Biol Psychiatry 1988, 23:285-294.
11. Cubeddu L.X., Hoffmann I.S. Operational characteristics of the inhibitory feedback mechanism for regulation of dopamine release via presynaptic receptors. J Pharmacol Exp Ther 1982, 223:497-501.
12. Engel J., Sharpless N.S. Long-lasting depletion of dopamine in the rat amygdala induced by kindling stimulation. Brain Res 1977, 136:381-386.
13. Fisher R.S., Leppik I. Debate: when does a seizure imply epilepsy?. Epilepsia 2008, 49:7-12.
14. Ginovart N., Wilson A.A., Houle S., Kapur S. Amphetamine pretreatment induces a change in both D2-Receptor density and apparent affinity: a [11C]raclopride positron emission tomography study in cats. Biol Psychiatry 2004, 55:1188-1194.
15. Glenthøj B.Y., Hemmingsen R. Dopaminergic sensitization: implications for the pathogenesis of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 1997, 21:23-46.
16. Gören M.Z., Aker R., Yananli H.R., Onat F.Y. Extracellular concentrations of catecholamines and amino acids in the dorsomedial hypothalamus of kindled rats. A microdialysis study. Pharmacology 2003, 68:190-197.
17. Grace A.A., Floresco S.B., Goto Y., Lodge D.J. Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends Neurosci 2007, 30:220-227.
18. Harrison C., Traynor J.R. The [35S]GTPgammaS binding assay: approaches and applications in pharmacology. Life Sci 2003, 74:489-508.
19. Hsu K.S., Huang C.C., Su M.T., Tsai J.J. L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism. J Pharmacol Exp Ther 1996, 279:740-747.
20. Ikarashi Y., Takahashi A., Ishimaru H., Arai T., Maruyama Y. Regulation of dopamine D1 and D2 receptors on striatal acetylcholine release in rats. Brain Res Bull 1997, 43:107-115.
21. Kenakin T. Pharmacologic analysis of drug-receptor interaction 1993, Raven Press, Ltd., New York. Second edition.
22. Kotecha S.A., Oak J.N., Jackson M.F., Perez Y., Orser B.A., Van Tol H.H.M., et al. A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission. Neuron 2002, 35:1111-1122.
23. Lipska B.K., Jaskiw G.E., Weinberger D.R. Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: a potential animal model of schizophrenia. Neuropsychopharmacology 1993, 9:67-75.
24. Lodge D.J., Grace A.A. Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends Pharmacol Sci 2011, 32:507-513.
25. Luna-Munguia H., Orozco-Suarez S., Rocha L. Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. Neuropharmacology 2011, 61:807-814.
26. Maidment N.T., Brumbaugh D.R., Rudolph V.D., Erdelyi E., Evans C.J. Microdialysis of extracellular endogenous opioid peptides from rat brain in vivo. Neuroscience 1989, 33:549-557.
27. Meurs A., Clinckers R., Ebinger G., Michotte Y., Smolders I. Seizure activity and changes in hippocampal extracellular glutamate, GABA, Dopamine and serotonin. Epilepsy Res 2008, 78:50-59.
28. Mittleman G., LeDuc P.A., Whishaw I.Q. The role of D1 and D2 receptors in the heightened locomotion induced by direct and indirect dopamine agonists in rats with hippocampal damage: an animal analogue of schizophrenia. Behav Brain Res 1993, 55:253-267.
29. Mori A., Hiramatsu M., Namba S., Nishimoto A., Ohmoto T., Mayanagi Y., et al. Decreased dopamine level in the epileptic focus. Res Commun Chem Pathol Pharmacol 1987, 56:157-164.
30. Otmakhova N.A., Lisman J.E. Dopamine selectively inhibits the direct cortical pathway to the CA1 hippocampal region. J Neurosci 1998, 19:1437-1445.
31. Pacia S.V., Doyle W.K., Broderick P.A. Biogenic amines in the human neocortex in patients with neocortical and mesial temporal lobe epilepsy: identification with in situ microvoltammetry. Brain Res 2001, 899:106-111.
32. Paladini C.A., Robinson S., Morikawa H., Williams J.T., Palmiter R.D. Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proc Natl Acad Sci U S A 2003, 100:2866-2871.
33. Paxinos G., Watson Ch. The rat brain in stereotaxic coordinates 2007, Elsevier, Amsterdam. sixth ed.
34. Peleg-Raibstein D., Feldon J. Effects of dorsal and ventral hippocampal NMDA stimulation on nucleus accumbens core and shell dopamine release. Neuropharmacology 2006, 51:947-957.
35. Racine R.J. Modification of seizure activity by electrical stimulation. I. Afterdischarge threshold. Electroencephalogr Clin Neurophysiol 1972, 32:269-279.
36. Racine R., Rose P.A., Burnham W.M. Afterdischarge thresholds and kindling rates in dorsal and ventral hippocampus and dentate gyrus. Can J Neurol Sci 1977, 4:273-278.
37. Rocha L., Alonso-Vanegas M., Villeda-Hernández J., Mújica M., Cisneros-Franco J.M., López-Gómez M., et al. Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy. Neurobiol Dis 2012, 45:499-507.
38. Sales N., Martres M.P., Bouthenet M.L., Schwartz J.C. Ontogeny of dopaminergic D-2 receptors in the rat nervous system: characterization and detailed autoradiographic mapping with [125I]iodosulpride. Neuroscience 1989, 28:673-700.
39. Sato M. Long-lasting supersensitivity to methamphetamine following amygdaloid kindling in cats: the relationship between limbic epilepsy and the psychotic state. Biol Psychiatry 1983, 18:525-536.
40. Taepavarapruk P., Floresco S.B., Phillips A.G. Hyperlocomotion and increased dopamine efflux in the rat nucleus accumbens evoked by electrical stimulation of the ventral subiculum: role of ionotropic glutamate and dopamine D1 receptors. Psychopharmacology (Berl) 2000, 151:242-251.
41. Trimble M. The relationship between epilepsy and schizophrenia: a biochemical hypothesis. Biol Psychiatry 1977, 12:299-304.
42. Turski L., Cavalheiro E.A., Bortolotto Z.A., Ikonomidou-Turski C., Kleinrok Z., Turski W.A. Dopamine-sensitive anticonvulsant site in the rat striatum. J Neurosci 1988, 8:4027-4037.
43. Wahnschaffe U., Löscher W. Anticonvulsant effects of ipsilateral but not contralateral microinjections of the Dopamine D2 agonist LY171555 into the nucleus accumbens of amygdala-kindled rats. Brain Res 1991, 553:181-187.
44. Watanabe T., Morimoto K., Nakamura M., Hirao T., Ninomiya T., Ando N., et al. Kindling of the ventral tegmental area induces supersensitivity in the central dopamine system. Brain Res 2004, 1003:194-198.
45. Werhahn K.J., Landvogt C., Klimpe S., Buchholz H.-G., Yakushev I., Siessmeier T., et al. Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: an [18F] Fallypride PET Study. Epilepsia 2006, 47:1392-1396.
46. Wilkison D.M., Halpern L.M. Turnover kinetics of dopamine and norepinephrine in the forebrain after kindling in rats. Neuropharmacology 1979, 18:219-222.
47. Wolf M.E., Roth R.H. Autoreceptor regulation of dopamine synthesis. Ann N Y Acad Sci 1990, 604:323-343.
48. Yakushev I.Y., Dupont E., Buchholz H.G., Tillmanns J., Debus F., Cumming P., et al. In vivo imaging of dopamine receptors in a model of temporal lobe epilepsy. Epilepsia 2010, 51:415-422.