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Volumn 109, Issue 45, 2012, Pages 18245-18246

Next-generation antibody discovery platforms

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIBODY; ANTIGEN; BINDING PROTEIN; IMMUNOGLOBULIN; POLYPEPTIDE; REAGENT;

EID: 84868563293     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1216406109     Document Type: Note
Times cited : (15)

References (11)
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    • Construction of a rationally designed antibody platform for sequencing-assisted selection
    • Larman HB, Xu GJ, Pavlova NN, Elledge SJ (2012) Construction of a rationally designed antibody platform for sequencing-assisted selection. Proc Natl Acad Sci USA 109:18523-18528.
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    • Larman, H.B.1    Xu, G.J.2    Pavlova, N.N.3    Elledge, S.J.4
  • 2
    • 78651390679 scopus 로고    scopus 로고
    • Sequencing antibody repertoires: The next generation
    • Fischer N (2011) Sequencing antibody repertoires: the next generation. MAbs 3(1):17-20.
    • (2011) MAbs , vol.3 , Issue.1 , pp. 17-20
    • Fischer, N.1
  • 3
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    • An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity
    • Wu TT, Kabat EA (1970) An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med 132(2):211-250.
    • (1970) J Exp Med , vol.132 , Issue.2 , pp. 211-250
    • Wu, T.T.1    Kabat, E.A.2
  • 4
    • 84882491131 scopus 로고    scopus 로고
    • Application of ultra-high throughput sequencing and microarray technologies in pharmacogenomics testing
    • ed Dasgupta A (Elsevier, London)
    • Hardiman G (2012) Application of ultra-high throughput sequencing and microarray technologies in pharmacogenomics testing. Therapeutic Drug Monitoring, ed Dasgupta A (Elsevier, London), pp 144-159.
    • (2012) Therapeutic Drug Monitoring , pp. 144-159
    • Hardiman, G.1
  • 5
    • 78649893449 scopus 로고    scopus 로고
    • By-passing in vitro screening - Next generation sequencing technologies applied to antibody display and in silico candidate selection
    • Ravn U, et al. (2010) By-passing in vitro screening - next generation sequencing technologies applied to antibody display and in silico candidate selection. Nucleic Acids Res 38(21):e193.
    • (2010) Nucleic Acids Res , vol.38 , Issue.21
    • Ravn, U.1
  • 6
    • 77951586447 scopus 로고    scopus 로고
    • Strategies and challenges for the next generation of therapeutic antibodies
    • Beck A, Wurch T, Bailly C, Corvaia N (2010) Strategies and challenges for the next generation of therapeutic antibodies. Nat Rev Immunol 10(5):345-352.
    • (2010) Nat Rev Immunol , vol.10 , Issue.5 , pp. 345-352
    • Beck, A.1    Wurch, T.2    Bailly, C.3    Corvaia, N.4
  • 7
    • 0036020660 scopus 로고    scopus 로고
    • Protein microarrays: Challenges and promises
    • DOI 10.1517/14622416.3.4.527
    • Talapatra A, Rouse R, Hardiman G (2002) Protein microarrays: challenges and promises. Pharmacogenomics 3(4):527-536. (Pubitemid 34814680)
    • (2002) Pharmacogenomics , vol.3 , Issue.4 , pp. 527-536
    • Talapatra, A.1    Rouse, R.2    Hardiman, G.3
  • 8
    • 27144431943 scopus 로고    scopus 로고
    • Selecting and screening recombinant antibody libraries
    • Hoogenboom HR (2005) Selecting and screening recombinant antibody libraries. Nat Biotechnol 23(9):1105-1116.
    • (2005) Nat Biotechnol , vol.23 , Issue.9 , pp. 1105-1116
    • Hoogenboom, H.R.1
  • 9
    • 60749123372 scopus 로고    scopus 로고
    • Modelling the human immune response: Performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens
    • Lloyd C, et al. (2009) Modelling the human immune response: Performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens. Protein Eng Des Sel 22(3):159-168.
    • (2009) Protein Eng des Sel , vol.22 , Issue.3 , pp. 159-168
    • Lloyd, C.1
  • 10
    • 39149087988 scopus 로고    scopus 로고
    • The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies
    • Rothe C, et al. (2008) The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies. J Mol Biol 376(4):1182-1200.
    • (2008) J Mol Biol , vol.376 , Issue.4 , pp. 1182-1200
    • Rothe, C.1
  • 11
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    • Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display
    • Hanes J, Schaffitzel C, Knappik A, Plückthun A (2000) Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display. Nat Biotechnol 18(12):1287-1292.
    • (2000) Nat Biotechnol , vol.18 , Issue.12 , pp. 1287-1292
    • Hanes, J.1    Schaffitzel, C.2    Knappik, A.3    Plückthun, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.