Induction of β-Glucuronidase release by cytostatic agents in small tumors

Molecular Pharmaceutics

Volumn 9, Issue 11, 2012, Pages 3277-3285

  Antunes, Inês F ^a   Haisma, Hidde J ^a   Elsinga, Philip H ^a   Di Gialleonardo, Valentina ^a   Waarde, Aren Van ^a   Willemsen, Antoon T M ^a   Dierckx, Rudi A ^a   De Vries, Erik F J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

glucuronidase; 18F FEAnGA; cytostatics; prodrug; small tumors; treatment

Indexed keywords

1 OXO [4 (2 FLUOROETHYL CARBAMOYLOXYMETHYL) 2 NITROPHENYL] OXO BETA D GLUCOPYRONURONATE; BETA GLUCURONIDASE; CARMUSTINE; DOXORUBICIN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TRACER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL INFILTRATION; CELL VIABILITY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME RELEASE; EX VIVO STUDY; FLOW CYTOMETRY; GLIOMA; HISTOCHEMISTRY; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; INDUCTION CHEMOTHERAPY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RAT; SINGLE DRUG DOSE; TUMOR NECROSIS; TUMOR VOLUME;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; CARMUSTINE; CYTOSTATIC AGENTS; DOXORUBICIN; FLOW CYTOMETRY; FLUORINE RADIOISOTOPES; GLIOMA; GLUCURONATES; GLUCURONIDASE; LEUKOCYTES; MALE; NECROSIS; POSITRON-EMISSION TOMOGRAPHY; PRODRUGS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84868556377     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300327w     Document Type: Article

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