Depression, testosterone concentration, sexual dysfunction and methadone use among men with hypogonadism and HIV infection

AIDS and Behavior

Volumn 16, Issue 8, 2012, Pages 2236-2243

  Lari, Mahmood Amini ^a   Parsa, Nader ^a   Marzban, Maryam ^b   Shams, Mesbah ^c   Faramarzi, Hossain ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Depression; HIV; Hypogonadism; Iran; Sexual function; Testosterone

Indexed keywords

METHADONE; TESTOSTERONE;

ADULT; ARTICLE; BLOOD; CROSS-SECTIONAL STUDY; DEPRESSION; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOGONADISM; IRAN; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OPIATE ADDICTION; OPIATE SUBSTITUTION TREATMENT; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; PSYCHOSEXUAL DISORDER; QUESTIONNAIRE; SEXUAL DYSFUNCTION; SOCIOECONOMICS; STATISTICAL MODEL;

ADULT; CROSS-SECTIONAL STUDIES; DEPRESSION; FEMALE; HIV INFECTIONS; HUMANS; HYPOGONADISM; IRAN; LOGISTIC MODELS; MALE; METHADONE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OPIATE SUBSTITUTION TREATMENT; OPIOID-RELATED DISORDERS; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; SEXUAL DYSFUNCTIONS, PSYCHOLOGICAL; SOCIOECONOMIC FACTORS; TESTOSTERONE;

EID: 84868543959     PISSN: 10907165     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10461-012-0234-x     Document Type: Article

References (38)

1. Dobs AS, Dempsey MA, Landeson PW, Polk BF. Endocrine disorders in men infected with human immunodeficiency virus. Am J Med. 1998;84:611-5.
2. Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med. 2004;350:482-92.
3. Grinspoon S, Corcoran C, Stanley T, Baaj A, Basgoz N, Klibanski A. Effects of hypogonadism and testosterone administration on depression indices in Men with HIV infection. J Clin Endocrinol Metab. 2000;85:60-5.
4. Wunder DM, Bersinger NA, Fux CA, et al. Hypogonadism in HIV-1-infected men is common and does not resolve during antiretroviral therapy. Antivir Ther. 2007;12:261-5.
5. Dobs AS. Androgen therapy in aids wasting. Baillieres Clin Endocrinol Metab. 1998;12:379-90.
6. Wahlstrom JT, Dobs AS. Acute and long-term effects of aids and injection drug use on gonadal function. J Acquir Immune Defic Syndr. 2000;25(1):27-36.
7. Dobs A. Role of testosterone in maintaining lean body mass and bone density in HIV-infected patients. Int J Impot Res. 2003; 15(4):S21-5.
8. Crum NF, Furtek KJ, Olson PE, Amling CL, Wallace MR. A review of hypogonadism and erectile dysfunction among men with HIV infection during the pre and post-HAART eras: diagnosis, pathogenesis, and management. AIDS Patient Care STDs. 2005;19:655-71.
9. Trotta MP, Ammassari A, Murri R, Monforte AD, Antinori A. Sexual dysfunction in HIV infection. Lancet. 2007;369(9565): 905-6.
10. Asboe D, Catalan J, Mandalia S, et al. Sexual dysfunction in HIV-positive men is multi-factorial: a study of prevalence and associated factors. AIDS Care. 2007;19:955-65.
11. Cotton DJ. Sexual Dysfunction and HIV Infection. AIDS Clinical Care. 2000;12(5):39-46.
12. Colson AE, Keller MJ, Sax PE, Pettus PT, Platt R, Choo PW. Male sexual dysfunction associated with antiretroviral therapy. J Acquir Immune Defic Syndr. 2002;30:27-32.
13. Baischer W, Koinig G, Hartmann B. Hypothalamiopituitary- gonadal axis in depressed premenopausal women: elevated blood testosterone concentrations compared to normal controls. Psychoneuroendocrinology. 1995;20:553-9.
14. Osran H, Reist C, Chen CC, Lifrak ET, Chicz-DeMet A, Parker L. Adrenal androgens and cortisol in major depression. Am J Psychiatr. 1993;150:806-9.
15. Speroff L, Glass RH, Kase NG. Clinical Gynecologic Endocrinology and Infertility. 5th ed. Baltimore: Willimas & Wilkins; 1994. p. 160-1.
16. Ulrich R, Hengge MD. Testosterone replacement for hypogonadism: clinical findings and best practices. AIDS Read. 2003; 13:S15.
17. Vescovi PP, Pezzarossa A, Ceresini G, Rastelli G, Valenti G, Gerra G. Effects of dopamine receptor stimulation on opiateinduced modifications of pituitary-gonadal function. Horm Res. 1985;21:155-9.
18. Woody G, McLellan T, O'Brien C, et al. Hormone secretion in methadone-dependent and abstinent patients. NIDA Res Monogr. 1988;81:216-23.
19. Adams ML, Sewing B, Forman JB, Meyer ER, Cicero TJ. Opioid-induced suppression of rat testicular function. J Pharmacol Exp Ther. 1993;266:323-8.
20. Singh HH, Purohit V, Ahluwalia BS. Methadone blocks dopamine-mediated release of gonadotropins in rat hypothalamus. Neuroendocrinology. 1982;34:347-52.
21. Brown TT, Wisniewski AB, Dobs AS. Gonadal and adrenal abnormalities in drug users: cause or consequence of drug use behavior and poor health outcomes. Am J Infect Dis. 2006;2(3): 130-5.
22. Cohen S, Kühn KU, Sträter B, Scherbaum N, Weig W. Adverse side-effect on sexual function caused by psychotropic drugs and psychotropic substances. Nervenarzt. 2010;81(9):1129-37.
23. Quaglio G, Lugoboni F, Pattaro C, Melara B, Mezzelani P, Des Jarlais DC. Erectile dysfunction in male heroin users, receiving methadone and buprenorphine maintenance treatment. Drug Alcohol Depend. 2008;94:12-8.
24. Peles E, Schreiber S, Naumovsky Y, Adelson M. Depression in methadone maintenance treatment patients. Rate and risk factors. J Affect Disord. 2007;99:213-20.
25. Razzaghi E, Movaghar A, Green T, Khoshnood K. Profiles of risk: a qualitative study of injecting drug users in Tehran, Iran. Harm Reduc J. 2006;3:12.
26. Razzaghi E, Nassirimanesh B, Afshar P, Ohiri K, Claeson M, Power R. HIV/AIDS harm reduction in Iran. Lancet. 2006;368: 434-5.
27. Gouya MM. National report on HIV and AIDS cases. Tehran: Disease Management Center, Ministry of Health and Medical Education; 2008.
28. Gouya MM. National Report on HIV and AIDS Cases. Disease Management Center, Ministry of Health and Medical Education. Tehran: Islamic Republic of Iran; 2006.
29. Schrader S, Mills A, Scheperle M, Block JE. Improvement in sexual functioning and satisfaction in nonresponders to testosterone gel: clinical effectiveness in hypogonadal HIV-positive males. Clin Cornerstone. 2005;7:S26-31.
30. Rodkjaer L, Laursen T, Balle N, Sodemann M. Depression in patients with HIV is under-diagnosed: a cross-sectional study in Denmark. HIV Medicine. 2010;11(1):46-53.
31. Fulk LJ, Kane BE, Phillips KD, Bopp CM, Hand GA. Depression in HIV-infected patients: Allopathic, complementary, and alternative treatments. J Psychosom Res. 2004;57:339-51.
32. Grinspoon S, Corcoran C, Lee K, et al. Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men with acquired immunodeficiency syndrome and wasting. J Clin Endocrinol Metab. 1996;81:4051-8.
33. Seidman SN, Rabkin JG. Testosterone replacement therapy for hypogonadal men with SSRI-refractory depression. J Affect Disord. 1998;48(2-3):157-61.
34. Zarrouf F, Artz S, Griffith J, Sirbu C, Kommor M. Testosterone and depression: systematic review and meta-analysis. Psychiatr Pract. 2009;15:289-305.
35. Rabkin JG, Wagner GJ, Rabkin R. A double-blind, placebocontrolled trial of testosterone therapy for HIV-positive men with hypogonadal symptoms. Arch Gen Psychiatry. 2000;57(2):141-7.
36. Crum-Cianflone NF, Bavaro M, Hale B, et al. Erectile dysfunction and hypogonadism among men with HIV. AIDS Patient Care STDS. 2007;21:9-19.
37. Gurbuz N, Mammadov E, Usta MF. Hypogonadism and erectile dysfunction: an overview. Asian J Androl. 2008;10:36-43.
38. Oscara MP, Corinab E, Carmenc SC, et al. Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitor. AIDS. 2010;24(2):255-64.