Adverse side-effect on sexual function caused by psychotropic drugs and psychotropic substances;Beeinträchtigung der sexualfunktion durch psychopharmaka und psychotrope substanzen

Nervenarzt

Volumn 81, Issue 9, 2010, Pages 1129-1139

  Cohen, S ^a   Kuhn K U ^b   Strater B ^b   Scherbaum, N ^c   Weig, W ^d  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

^d Chefarzt der Magdalenen Klinik   (Germany)

Author keywords

Anti depressants; Maintenance treatment; Medication side effects; Neuroleptics; Sexual dysfunction

Indexed keywords

AGOMELATINE; AMFEBUTAMONE; NEUROLEPTIC AGENT; PAROXETINE; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; SILDENAFIL; TRICYCLIC ANTIDEPRESSANT AGENT;

HUMAN; LIBIDO; MAINTENANCE THERAPY; PSYCHOEDUCATION; PSYCHOTHERAPY; REVIEW; SEXUAL DYSFUNCTION; SEXUAL FUNCTION;

FEMALE; HUMANS; MALE; PSYCHOTROPIC DRUGS; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; SEXUAL DYSFUNCTIONS, PSYCHOLOGICAL;

EID: 77957823942     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-010-3074-9     Document Type: Review

References (49)

1. Aizenberg D, Zemishlany Z, Dorfman-Etrog P, Weizman A (1995) Sexual dysfunction in male schizophrenic patients. J Clin Psychiatry 56:137-141
2. Aizenberg D, Modai I, Landa A et al (2001) Comparison of sexual dysfunction in male schizophrenic patients maintained on treatment with classical antipsychotics versus clozapine. J Clin Psychiatry 62:541-544
3. Bart G, Borg L, Schluger JH et al (2003) Suppressed prolactin response to dynorphin A1-13 in methadone-maintained versus control subjects. J Pharmacol Exp Ther 306:581-587
4. Bitter I, Basson BR, Dossenbach MR (2005) Antipsychotic traetment and sexual functioning in first-time neuroleptic-treated schizophrenic patients. Int Clin Psychopharmaco l20:19-21
5. Bliesener N, Albrecht S, Schwager A et al (2005) Plasma testosterone and sexual function in men receiving buprenorphine maintenance for opioid dependence, J Clin Endocrinol Metab 90:203-206
6. Bonierbale M, Lançon C, Tignol J (2003) The ELIXIR study: evaluation of sexual dysfunction in 4557 depressed patients in France, Curr Med Res Opin 19(2):114-124
7. Brennemann W, Stitz B, Van Ahlen H et al (1993) Treatment of idiopathic erectile dysfunction in men with the opiate antagonist naltrexone - a double-blind study. J Androl 14:407-410
8. Brown RT, Zueldorff M (2007) Opioid substitution with methadone and buprenorphine: Sexual dysfunction as a side effect of therapy. Heroin Addict Relat Clin Probl 9:35-44
9. Brown R, Balousek S, Mundt M, Fleming M (2005) Methadone maintenance and male sexual dysfunction, J Addict Dis 24:91-106
10. Cicero TJ, Bell RD, Wiest WG et al (1975) Function of the male sex organs in heroin and methadone users. New Engl J Med 292:882-887
11. Clayton A (2001) Recognition and assessment of sexual dysfunction associated with depression. J Clin Psychiatry 62(Suppl 3):5-9
12. Cohen S, Kühn K-U, Bender S et al (2007) Sexual impairment in psychiatric inpatients: Focus on depression. Pharmacopsychiatry 40:58-63
13. Cushman P (1972) Sexual behavior in heroin addiction and methadone maintenance. NY State J Med 72:1261-1265
14. Cutler AJ (2003) Sexual dysfunction and antipsychotic treatment. Psychoneuroendocrinology 5(Suppl 2):69-82
15. Daniell HW, Lentz R, Mazer R (2006) Open-label pilot study of testosterone patch therapy in men with opioid-induced androgen deficiency. J Pain 7:200-210
16. Eap CB, Buclin T, Baumann P (2002) Individual variability of the clinical pharmacokinetics of methadone. Clin Pharmacokinet 41:1153-1193
17. Fortier P, Mottard JP, Trudel G, Even S (2003) Study of sexual-related characteristics in young adults with schizophrenia treated with novel neuroleptics and in a comparison group of young adults. Schizophr Bull 29:559-572
18. Friedman S, Harrison G (1984) Sexual histories, attitudes, and behavior of schizophrenic and "normal" women. Arch Sex Behav 13:555-567
19. Hallinan R, Byrne A, Agho K et al (2007) Hypogonadism in men receiving methadone and buprenorphine maintenance treatment. Int J Androl 30:1-9
20. Hartmann U, Becker AJ, Ückert S, Stief C (2006) Sexualstörungen - sexuelle Funktionsstörungen. In: Förstl, Hautzinger M, Roth G (Hrsg) Neurobiologie psychisher Störungen. Springer, Heidelberg, S 763-806
21. Howes OD, Wheeler MJ, Pilowsky LS (2007) Sexual function and gonadal hormones in patients taking antipsychotic treatment for schizophrenia or schizoaffective disorder. 68:361-367
22. Hummer M, Kemmler G, Kurz M et al (1999) Sexual disturbances during clozapine and haloperidol treatment for schizophrenia. Am J Psychiatry 156:631-633
23. Kalyani RR, Gavini S, Dobs AS (2007) Male hypogonadism in systemic disease. Endocrinol Metab Clin N Am 36:333-348
24. Kelly DL, Conley RR (2006) A randomized double-blind 12-week study of quetiapine, risperidon or fluphenazine on sexual functioning in people with schizophrenia. Psychoneuroendocrinology 31:340-346
25. Kennedy SH, Dickens SE, Eisfeld BS et al (1999) Sexual dysfunction before antidepressant therapy in major depression. J Affect Disord 56:201-208
26. Kockott G, Fahrner EM (2004) Sexuelle Funktionsstörungen. In: Kockott G, Fahrner EM (Hrsg) Sexualstörungen. Thieme, Stuttgart New York, S 1-76
27. Masters WH, Johnson VE (1970) Human sexual inadequacy. Little Brown, Boston
28. McCann E (2000) The expression of sexuality in people with psychosis: breaking the taboos. J Adv Nurs 32:132-138
29. Mendelson JH, Mendelson JE, Patch V (1975) Plasma testosterone levels in heroin addiction and during methadone maintenance. J Pharmacol Exp Ther 192:211-217
30. Montejo AL, Llorca GL, Izquierdo JA, Rico-Villadermos F (2001) Incidence of sexual dysfunction associated with antidepressant agents: a prospective muliticenter study of 1022 outpatients. J Clin Psychiatry 62(Suppl 3):10-21
31. Nestoros JN, Lehmann HE, Ban TA (1981) Sexual behavior of the male schizophrenic: the impact of illness and medications. Arch Sex Behav 10(5):421-442
32. Nurnberg HG, Hensley PL, Heiman JR et al (2008) Sildenafil treatment of women with antidepressant-associated sexual dysfunction: a randomized controlled trial. JAMA 300(4):395-404
33. Rado S (1926) The psychic effects of intoxicants: An attempt to evolve a psycho-analytical theory of morbid cravings. Int J Psychoanal 7:396-413
34. Riecher-Rössler A, Schmid C, Bleuer S, Birhäuser M (2009) Antipsychotika und Hyperprolaktinämie: Pathophysiologie, klinische Bedeutung, Abklärung und Therapie. Neuropsychiatr 23(2):71-83
35. Robinson DS, Roberts DL, Smith JM et al (1996) The safety profile of nefazodone. J Clin Psychiatry 57(Suppl 2):31-38
36. Ryback RS (2004) Naltrexone in the treatment of adolescent sexual offenders. J Clin Psychiatry 65:982-986
37. Sathe RS, Komisaruk BR, Ladas AK, Godbole SV (2001) Naltrexone-induced augmentation of sexual response in men. Arch Med Res 32:221-226
38. Scherbaum N, Heigl-Evers A (1996) Psychodynamische Aspekte der Substitutionstherapie Heroinabhängiger mit Methadon. Psychother Psychosom Med Psychol 46:47-51
39. Smith S, O'Keane V, Murray R (2002) Sexual dysfunction in patients taking conventional antipsychotic medication. Br J Psychiatry 181:49-55
40. Taylor MJ (2006) Strategies for managing antidepressant-induced sexual dysfunction: a review. Curr Psychiatry Rep 8(6):431-436
41. Teusch L, Scherbaum N, Böhme H et al (1995) Different patterns of sexual dysfunctions associated with psychiatric disorders and psychopharmacological treatment. Pharmacopsychiatry 28:84-92
42. Thase ME, Clayton AH, Haight BR et al (2006) A double-blind comparison between bupropion XL and venlafaxine XR: sexual functioning, antidepressant efficacy and tolerability. J Clin Psychopharmacol 26(05):482-488
43. Wang PS, Gilman SE, Kessler RC et al (2000) Initiation of and adherence to treatment for mental disorders: examination of patient advocate group members in 11 countries. Med Care 38(9):926-936
44. Weig W (2006) Sexuelle Funktionsstörungen aus nervenärztlicher Perspektive. Nervenarzt 77:101-109
45. Weig W (2000) Die Rolle von Psychiatrie und Psychotherapie in der Sexualmedizin nach der Markteinführung von Viagra®. Nervenarzt 71:218-221
46. Westheide J, Cohen S, Bender S et al (2007) Sexual dysfunction in psychiatric inpatients, The role of antipsychotic medication. Pharmacopsychiatry 40(4):1405
47. Westheide J, Cvetanovska G, Albrecht C et al (2008) Prolactin, subjective well-being and sexual dysfunction: an open label observational study comparing quetiapine with risperidone. J Sex Med 5(12):2816-2826
48. Zajecka J (2001) Strategies for treatment of antidepressant-related sexual dysfunction. J Clin Psychiatry 62(Suppl 3):35-43
49. Zettel S, Hartlapp J (1997) Sexualstörungen durch Krankheit und Therapie. Springer, Berlin Heidelberg