A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation

Mutagenesis

Volumn 27, Issue 6, 2012, Pages 713-719

  Reshat, Reshat ^a   Priestley, Catherine C ^b   Gooderham, Nigel J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; GENOMIC DNA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; OLIGONUCLEOTIDE; TRIPLE HELIX OLIGONUCLEOTIDE 27; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL FREE SYSTEM; CONTROLLED STUDY; CYTOTOXICITY; DNA BASE COMPOSITION; DNA SEQUENCE; ENZYME DEGRADATION; GENE LOCUS; GENE MUTATION; GENOTOXICITY; HUMAN; HUMAN CELL; MUTAGENIC ACTIVITY; PRIORITY JOURNAL; TRIPLE HELIX;

CELL LINE; DNA; DNA DAMAGE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE TARGETING; GENETIC LOCI; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTATION; OLIGONUCLEOTIDES; POLYMERASE CHAIN REACTION; PURINES; SEQUENCE ANALYSIS, DNA;

EID: 84868539024     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ges037     Document Type: Article

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