메뉴 건너뛰기




Volumn 23, Issue 6, 2010, Pages 1635-1640

Triplet schedule of weekly 5-Fluorouracil and alternating irinotecan or oxaliplatin in advanced colorectal cancer: A dose-finding and phase II study

Author keywords

5 Fluorouracil; Advanced colorectal cancer; CPT 11; l OHP

Indexed keywords

FLUOROURACIL; IRINOTECAN; OXALIPLATIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; PLATINUM COMPLEX;

EID: 77951706637     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000805     Document Type: Article
Times cited : (24)

References (32)
  • 4
    • 0025058867 scopus 로고
    • Relationship between dihydropyrimidine dehidrogenase activity and plasma 5-fluorouracil levels with evidence for circadian varation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion
    • Harris BE, Song R, Soong SJ and Diasio RB: Relationship between dihydropyrimidine dehidrogenase activity and plasma 5-fluorouracil levels with evidence for circadian varation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res 50: 197-201, 1990.
    • (1990) Cancer Res , vol.50 , pp. 197-201
    • Harris, B.E.1    Song, R.2    Soong, S.J.3    Diasio, R.B.4
  • 5
    • 0026629594 scopus 로고
    • DNA cell cycle distrubution and glutathione (GSH) content according to circadian stage in bone marrow of cancer patients
    • Smaaland R, Abrahamsen JF, Svardal AM, et al: DNA cell cycle distrubution and glutathione (GSH) content according to circadian stage in bone marrow of cancer patients. Br J Cancer 66: 39-45, 1992.
    • (1992) Br J Cancer , vol.66 , pp. 39-45
    • Smaaland, R.1    Abrahamsen, J.F.2    Svardal, A.M.3
  • 6
    • 0035340843 scopus 로고    scopus 로고
    • Fluorouracil modulation in colorectal cancer: Lack of improvement with N-phosphonoacetyl-l-aspartic acid or oral leucovorin or interferon, but enhanced therapeutic index with weekly 24-hour infusion schedule-An Eastern Cooperative Oncology Group/Cancer and Leukemia Group B Study
    • O'Dwyer PJ, Manola J, Valone FH, et al: Fluorouracil modulation in colorectal cancer: lack of improvement with N-phosphonoacetyl-l-aspartic acid or oral leucovorin or interferon, but enhanced therapeutic index with weekly 24-hour infusion schedule-An Eastern Cooperative Oncology Group/Cancer and Leukemia Group B Study. J Clin Oncol 19: 2413-2421, 2001.
    • (2001) J Clin Oncol , vol.19 , pp. 2413-2421
    • O'Dwyer, P.J.1    Manola, J.2    Valone, F.H.3
  • 7
    • 0029012118 scopus 로고
    • A Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group study
    • Leichman CG, Fleming TR, Muggia FM, et al: A Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study. J Clin Oncol 13: 1303-1311, 1995.
    • (1995) J Clin Oncol , vol.13 , pp. 1303-1311
    • Leichman, C.G.1    Fleming, T.R.2    Muggia, F.M.3
  • 8
    • 0001446649 scopus 로고    scopus 로고
    • Weekly 24-h infusion of high-dose 5-Fluorouracil with or without Folinic Acid vs bolus 5-FU/FA (NCCTG/Mayo) in advanced colorectal cancer: A randomized phase III study of the EORTC GITCCG and the AIO
    • Schmoll H, Köhne C, Lorenz M, et al: Weekly 24-h infusion of high-dose 5-Fluorouracil with or without Folinic Acid vs bolus 5-FU/FA (NCCTG/Mayo) in advanced colorectal cancer: a randomized phase III study of the EORTC GITCCG and the AIO. Proc Am Soc Clin Oncol 10: 287, a935, 2000.
    • (2000) Proc Am Soc Clin Oncol , vol.10 , Issue.287
    • Schmoll, H.1    Köhne, C.2    Lorenz, M.3
  • 9
    • 0041055512 scopus 로고    scopus 로고
    • Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer
    • International Organization for Cancer Chronotherapy
    • Levi F, Zidani R and Misset JL: Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. International Organization for Cancer Chronotherapy. Lancet 350: 681-686, 1997.
    • (1997) Lancet , vol.350 , pp. 681-686
    • Levi, F.1    Zidani, R.2    Misset, J.L.3
  • 11
    • 0035890465 scopus 로고    scopus 로고
    • Randomized multicenter phase II study comparing a combination of fluorouracil and folinic acid and alternating irinotecan and oxaliplatin with oxaliplatin and irinotecan in fluorouracil pretreated metastatic colorectal cancer patients
    • Bècourarn Y, Gamelin E, Coudert B, et al: Randomized multicenter phase II study comparing a combination of fluorouracil and folinic acid and alternating irinotecan and oxaliplatin with oxaliplatin and irinotecan in fluorouracil pretreated metastatic colorectal cancer patients. J Clin Oncol 19: 4195-4201, 2001.
    • (2001) J Clin Oncol , vol.19 , pp. 4195-4201
    • Bècourarn, Y.1    Gamelin, E.2    Coudert, B.3
  • 12
    • 0036605387 scopus 로고    scopus 로고
    • Triplet combination with irinotecan plus oxaliplatin plus continuous-infusion fluorouracil and leucovorin as first-line treatment in metastatic colorectal cancer: A multicenter phase II trial
    • Souglakos J, Mavroudis D, Kakolyris S, et al: Triplet combination with irinotecan plus oxaliplatin plus continuous-infusion fluorouracil and leucovorin as first-line treatment in metastatic colorectal cancer: a multicenter phase II trial. J Clin Oncol 20: 2651-2657, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 2651-2657
    • Souglakos, J.1    Mavroudis, D.2    Kakolyris, S.3
  • 13
    • 0036696465 scopus 로고    scopus 로고
    • Irinotecan, oxaliplatin, and 5-fluorouracil/leucovorin combination chemotherapy in advanced colorectal carcinoma: A phase II study
    • Calvo E, Cortes J, Rodriguez J, et al: Irinotecan, oxaliplatin, and 5-fluorouracil/leucovorin combination chemotherapy in advanced colorectal carcinoma: a phase II study. Clin Colorectal Cancer 2: 104-110, 2002.
    • (2002) Clin Colorectal Cancer , vol.2 , pp. 104-110
    • Calvo, E.1    Cortes, J.2    Rodriguez, J.3
  • 15
    • 0348013441 scopus 로고    scopus 로고
    • A phase II study of irinotecan plus chronomodulated oxaliplatin, 5-fluorouracil and folinic acid in advanced colorectal cancer patients
    • Garufi C, Bria E, Vanni B, et al: A phase II study of irinotecan plus chronomodulated oxaliplatin, 5-fluorouracil and folinic acid in advanced colorectal cancer patients. Br J Cancer 89: 1870-1875, 2003.
    • (2003) Br J Cancer , vol.89 , pp. 1870-1875
    • Garufi, C.1    Bria, E.2    Vanni, B.3
  • 16
    • 12244287645 scopus 로고    scopus 로고
    • An open phase I study assessing the feasibility of the triple combination: Oxaliplatin plus irinotecan plus leucovorin/ 5-fluorouracil every 2 weeks in patients with advanced solid tumors
    • Ychou M, Conroy T, Seitz JF, Gourgou S, Hua A, Mery-Mignard D and Kramar A: An open phase I study assessing the feasibility of the triple combination: oxaliplatin plus irinotecan plus leucovorin/ 5-fluorouracil every 2 weeks in patients with advanced solid tumors. Ann Oncol 14: 481-489, 2003.
    • (2003) Ann Oncol , vol.14 , pp. 481-489
    • Ychou, M.1    Conroy, T.2    Seitz, J.F.3    Gourgou, S.4    Hua, A.5    Mery-Mignard, D.6    Kramar, A.7
  • 17
    • 4143148621 scopus 로고    scopus 로고
    • Dose-finding study of weekly 24-h continuous infusion of 5-fluorouracil associated with alternating oxaliplatin or irinotecan in advanced colorectal cancer patients
    • Cals L, Rixe O, Francois E, Favre R, Merad L, Deplanque G, Laadem A, Juin P, Bereder JM, Bernardini D and Herait P: Dose-finding study of weekly 24-h continuous infusion of 5-fluorouracil associated with alternating oxaliplatin or irinotecan in advanced colorectal cancer patients. Ann Oncol 15: 1018-1024, 2004.
    • (2004) Ann Oncol , vol.15 , pp. 1018-1024
    • Cals, L.1    Rixe, O.2    Francois, E.3    Favre, R.4    Merad, L.5    Deplanque, G.6    Laadem, A.7    Juin, P.8    Bereder, J.M.9    Bernardini, D.10    Herait, P.11
  • 18
    • 19944425122 scopus 로고    scopus 로고
    • First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): Results of a phase II study with a simplified biweekly schedule
    • Masi G, Allegrini G, Cupini S, et al: First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule. Ann Oncol 15: 1766-1772, 2004.
    • (2004) Ann Oncol , vol.15 , pp. 1766-1772
    • Masi, G.1    Allegrini, G.2    Cupini, S.3
  • 20
    • 2942574540 scopus 로고    scopus 로고
    • Spanish Cooperative Group for Gastrointestinal Tumor Therapy: Phase I study of the combination of oxaliplatin, irinotecan and continuous infusion 5-fluorouracil in digestive tumors
    • Abad A, Massuti B, Gallego J, Yuste AL, Manzano JL, Carrato A, Anton A, Marfa X and Diaz-Rubio E; Spanish Cooperative Group for Gastrointestinal Tumor Therapy: Phase I study of the combination of oxaliplatin, irinotecan and continuous infusion 5-fluorouracil in digestive tumors. Anticancer Drugs 15: 469-471, 2004.
    • (2004) Anticancer Drugs , vol.15 , pp. 469-471
    • Abad, A.1    Massuti, B.2    Gallego, J.3    Yuste, A.L.4    Manzano, J.L.5    Carrato, A.6    Anton, A.7    Marfa, X.8    Diaz-Rubio, E.9
  • 21
    • 4444371506 scopus 로고    scopus 로고
    • A phase II study of irinotecan alternated with a weekly schedule of oxaliplatin, high-dose leucovorin and 48-hour infusion 5-fluorouracil in patients with advanced colorectal cancer
    • Rosati G, Tucci A, Rinaldi A, et al: A phase II study of irinotecan alternated with a weekly schedule of oxaliplatin, high-dose leucovorin and 48-hour infusion 5-fluorouracil in patients with advanced colorectal cancer. Oncology 66: 371-378, 2004.
    • (2004) Oncology , vol.66 , pp. 371-378
    • Rosati, G.1    Tucci, A.2    Rinaldi, A.3
  • 24
    • 28644451453 scopus 로고    scopus 로고
    • An alternating rEgimen of irinotecan/ 5-fluorouracil/folinic acid and oxaliplatin/ 5-fluorouracil/folinic acid in metastatic colorectal cancer: A Phase II trial
    • Ferrari V, Valcamonico F, Amoroso V, Simoncini E, Vassalli L, Marpicati P, Rangoni G, Grisanti S, Pasinetti N and Marini G: An alternating rEgimen of irinotecan/ 5-fluorouracil/folinic acid and oxaliplatin/ 5-fluorouracil/folinic acid in metastatic colorectal cancer: a Phase II trial. Oncology 69: 283-289, 2005.
    • (2005) Oncology , vol.69 , pp. 283-289
    • Ferrari, V.1    Valcamonico, F.2    Amoroso, V.3    Simoncini, E.4    Vassalli, L.5    Marpicati, P.6    Rangoni, G.7    Grisanti, S.8    Pasinetti, N.9    Marini, G.10
  • 26
    • 33845236948 scopus 로고    scopus 로고
    • Multiple-target chemotherapy (LV-modulated 5-FU bolus and continuous infusion, oxaliplatin, CPT- 11) in advanced 5-FU-refractory colorectal cancer: MTD definition and efficacy evaluation. A phase I-II study
    • Bonetti A, Zaninelli M, Durante E, Fraccon AP, Franceschi T, Pasini F, Zustovich F and Brienza S: Multiple-target chemotherapy (LV-modulated 5-FU bolus and continuous infusion, oxaliplatin, CPT- 11) in advanced 5-FU-refractory colorectal cancer: MTD definition and efficacy evaluation. A phase I-II study. Tumori 92: 389-395, 2006.
    • (2006) Tumori , vol.92 , pp. 389-395
    • Bonetti, A.1    Zaninelli, M.2    Durante, E.3    Fraccon, A.P.4    Franceschi, T.5    Pasini, F.6    Zustovich, F.7    Brienza, S.8
  • 27
    • 33748463224 scopus 로고    scopus 로고
    • Biweekly oxaliplatin plus irinotecan and folinic acid-modulated 5-fluorouracil: A phase II study in pretreated patients with metastatic colo-rectal cancer
    • Comella P, Massidda B, Palmeri S, Putzu C, De Rosa V, Izzo F, Fiore F, Casaretti R and Sandomenico C: Biweekly oxaliplatin plus irinotecan and folinic acid-modulated 5-fluorouracil: a phase II study in pretreated patients with metastatic colo-rectal cancer. Anticancer Drugs 17: 985-992, 2006.
    • (2006) Anticancer Drugs , vol.17 , pp. 985-992
    • Comella, P.1    Massidda, B.2    Palmeri, S.3    Putzu, C.4    De Rosa, V.5    Izzo, F.6    Fiore, F.7    Casaretti, R.8    Sandomenico, C.9
  • 31
    • 33645309877 scopus 로고    scopus 로고
    • FOLFOXIRI (folin acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folin acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
    • Souglakos J, Andrulakis N, Syrigos K, et al: FOLFOXIRI (folin acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folin acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer 94: 798-805, 2006.
    • (2006) Br J Cancer , vol.94 , pp. 798-805
    • Souglakos, J.1    Andrulakis, N.2    Syrigos, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.