Circulating insulin-like growth factors may contribute substantially to insulin receptor isoform A and insulin receptor isoform B signalling

Molecular and Cellular Endocrinology

Volumn 365, Issue 1, 2013, Pages 17-24

  Varewijck, Aimee J ^a   Brugts, Michael P ^a   Frystyk, Jan ^b   Goudzwaard, Jeannette A ^a   Uitterlinden, Pieter ^a   Waaijers, Adriana M ^a   Feng, Yang ^c   Dimitrov, Dimiter S ^c   Lamberts, Steven W J ^a   Hofland, Leo J ^a   Janssen, Joseph A M J L ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Insulin; Insulin bioactivity; Insulin receptor isoforms; Insulin receptor KIRA assays; Insulin like growth factors

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR B; INSULIN RECEPTOR KINASE; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO; GENE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INSULIN LIKE ACTIVITY; IR A GENE; IR B GENE; LIMIT OF DETECTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RECEPTOR UPREGULATION; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

ANTIBODIES, NEUTRALIZING; ANTIGENS, CD; GENE EXPRESSION; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; KIDNEY; OSMOLAR CONCENTRATION; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; RECEPTOR, INSULIN; RECOMBINANT PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84868465951     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.08.021     Document Type: Article

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