Sequential expression of IGF-IB followed by active TGF-β1 induces synergistic pulmonary fibroproliferation in vivo

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 303, Issue 9, 2012, Pages

  Andonegui, Graciela ^a   Ni, Ai ^a   Léger, Caroline ^a   Kelly, Margaret M ^a   Wong, Josée F ^a   Jalloul, Ali ^a   Winston, Brent W ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Adenovirus; Mouse model; Pulmonary fibrosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; CYTOKINE; MESSENGER RNA; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; IN VIVO STUDY; LUNG; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG LAVAGE; LUNG PARENCHYMA; LYMPHOCYTE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ACTINS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CELL PROLIFERATION; COLLAGEN TYPE I; COLLAGEN TYPE III; CYTOKINES; FIBROBLASTS; GENE EXPRESSION; HUMANS; INFLAMMATION MEDIATORS; INSULIN-LIKE GROWTH FACTOR I; LUNG; LYMPHOCYTES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUTROPHILS; PULMONARY FIBROSIS; SUS SCROFA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84868372222     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00008.2012     Document Type: Article

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