Reducing medication regimen complexity for older patients prior to discharge from hospital: Feasibility and barriers

Journal of Clinical Pharmacy and Therapeutics

Volumn 37, Issue 6, 2012, Pages 637-642

  Elliott, R A ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

elderly; hospital; pharmacists; polypharmacy; prescribing

Indexed keywords

AGENTS ACTING ON THE EYE; ANALGESIC AGENT; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDIABETIC AGENT; CARDIOVASCULAR AGENT; CORTICOSTEROID; LAXATIVE; VITAMIN;

AGED; ANTICONVULSANT THERAPY; ARTICLE; FEMALE; GERIATRIC CARE; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OBSERVATIONAL STUDY; PHARMACIST; PHARMACIST ATTITUDE; PHYSICIAN; POLYPHARMACY; PRESCRIPTION; RETROSPECTIVE STUDY; TEACHING HOSPITAL; WARD;

AGE FACTORS; AGED; AGED, 80 AND OVER; FEASIBILITY STUDIES; FEMALE; HOSPITALS, TEACHING; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PATIENT DISCHARGE; PHARMACISTS; PHARMACY SERVICE, HOSPITAL; PROFESSIONAL ROLE; TIME FACTORS;

EID: 84868359532     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2012.01356.x     Document Type: Article

References (21)

1. Steinman MA, Hanlon JT,. Managing medications in clinically complex elders: 'There's got to be a happy medium'. JAMA, 2010; 304: 1592-1601.
2. Ingersoll KS, Cohen J, Ingersoll KS, Cohen J,. The impact of medication regimen factors on adherence to chronic treatment: a review of literature. J Behav Med, 2008; 31: 213-224.
3. Claxton AJ, Cramer J, Pierce C,. A systematic review of the associations between dose regimens and medication compliance. Clin Ther, 2001; 23: 1296-1310.
4. Choudhry NK, Fischer MA, Avorn J, et al. The implications of therapeutic complexity on adherence to cardiovascular medications. Arch Intern Med, 2011; 171: 814-822.
5. Col N, Fanale JE, Kronholm P,. The role of medication noncompliance and adverse drug reactions in hospitalizations of the elderly. Arch Intern Med, 1990; 150: 841-845.
6. Vik SA, Hogan DB, Patten SB, et al. Medication nonadherence and subsequent risk of hospitalisation and mortality among older adults. Drugs Aging, 2006; 23: 345-356.
7. Hilmer SN, McLachlan AJ, Le Couteur DG,. Clinical pharmacology in the geriatric patient. Fundam Clin Pharmacol, 2007; 21: 217-230.
8. Elliott RA, Marriott JL,. Standardised assessment of patients' capacity to manage medications: a review of published instruments. BMC Geriatrics, 2009; 9: 27.
9. George J, Phun YT, Bailey MJ, Kong DC, Stewart K,. Development and validation of the medication regimen complexity index. Ann Pharmacother, 2004; 38: 1369-1376.
10. Corsonello A, Pedone C, Lattanzio F, et al. Regimen complexity and medication nonadherence in elderly patients. Ther Clin Risk Manag, 2009; 5: 209-216.
11. Centre for Home Care Policy and Research. Medication regimen complexity in home health care. New York: Visiting Nurse Service of New York, 2010. Available from http://toolkit.techandaging.org/2011/03/08/medication-regime- complexity-in-home-health-care/ (Accessed 16/1/12).
12. Elliott RA, O'Callaghan CJ,. Impact of hospitalisation on the complexity of older patients' medication regimens and potential for regimen simplification. J Pharm Pract Res, 2011; 41: 21-25.
13. Mansur N, Weiss A, Beloosesky Y,. Relationship of in-hospital medication modifications of elderly patients to postdischarge medications, adherence, and mortality. Ann Pharmacother, 2008; 42: 783-789.
14. Viktil KK, Blix HS, Moger TA, Reikvam A,. Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems. Br J Clin Pharmacol, 2006; 63: 187-195.
15. Kripalani S, Yao X, Haynes RB,. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med, 2007; 167: 540-549.
16. Bangalore S, Kamalakkannan G, Parkar S, Messerli FH,. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med, 2007; 120: 713-719.
17. Richter A, Anton SE, Koch P, et al. The impact of reducing dose frequency on health outcomes. Clin Ther, 2003; 25: 2307-2335.
18. Barat I, Andreasen F, Damsgaard EMS,. Drug therapy in the elderly: what doctors believe and patients actually do. Br J Clin Pharmacol, 2001; 51: 615-622.
19. O'Leary KM, Stuchbery P, Taylor G,. Clinical pharmacist staffing levels needed to deliver clinical services in Australian hospitals. J Pharm Pract Res, 2010; 40: 217-221.
20. Woodward MC,. Deprescribing: achieving better health outcomes for older people through reducing medications. J Pharm Pract Res, 2003; 33: 323-328.
21. Travis SS, McAuley WJ, Dmochowski J, et al. Factors associated with medication hassles experienced by family caregivers of older adults. Patient Ed Counsel, 2007; 66: 51-57.