EspZ of enteropathogenic and enterohemorrhagic escherichia coli regulates type III secretion system protein translocation

mBio

Volumn 3, Issue 5, 2012, Pages

  Frankel, Gad ^a   Berger, Cedric N ^a   Crepin, Valerie F ^a   Baruch, Kobi ^b   Mousnier, Aurelie ^a   Rosenshine, Ilan ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84868338357     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00317-12     Document Type: Article

References (50)

1. Aili M, et al. 2008. Regulation of Yersinia Yop-effector delivery by translocated YopE. Int. J. Med. Microbiol. 298:183-192.
2. Erhardt M, Namba K, Hughes KT. 2010. Bacterial nanomachines: the flagellum and type III injectisome. Cold Spring Harb. Perspect. Biol. 2:a000299.
3. Cornelis GR. 2010. The type III secretion injectisome, a complex nano-machine for intracellular "toxin" delivery. Biol. Chem. 391:745-751.
4. Shames SR, et al. 2010. The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling. Cell. Microbiol. 12:1322-1339.
5. Laaberki MH, Janabi N, Oswald E, Repoila F. 2006. Concert of regulators to switch on LEE expression in enterohemorrhagic Escherichia coli O157:H7: interplay between Ler, GrlA, HNS and RpoS. Int. J. Med. Mi-crobiol. 296:197-210.
6. Deng W, et al. 2004. Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proc. Natl. Acad. Sci. U. S. A. 101: 3597-3602.
7. Mills E, Baruch K, Charpentier X, Kobi S, Rosenshine I. 2008. Real-time analysis of effector translocation by the type III secretion system of enter-opathogenic Escherichia coli. Cell Host Microbe 3:104-113.
8. Chen HD, Frankel G. 2005. Enteropathogenic Escherichia coli: unravelling pathogenesis. FEMS Microbiol. Rev. 29:83-98.
9. Pennington H. 2010. Escherichia coli O157. Lancet 376:1428-1435.
10. Frankel G, Phillips AD. 2008. Attaching effacing Escherichia coli and paradigms of tir-triggered actin polymerization: getting off the pedestal. Cell. Microbiol. 10:549-556.
11. Frankel G, et al. 1998. Enteropathogenic and enterohaemorrhagic Esch-erichia coli: more subversive elements. Mol. Microbiol. 30:911-921.
12. McDaniel TK, Jarvis KG, Donnenberg MS, Kaper JB. 1995. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc. Natl. Acad. Sci. U. S. A. 92:1664-1668.
13. Jerse AE, Yu J, Tall BD, Kaper JB. 1990. A genetic locus of enteropatho-genic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells. Proc. Natl. Acad. Sci. U. S. A. 87:7839-7843.
14. Jarvis KG, et al. 1995. Enteropathogenic Escherichia coli contains a putative type-III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation. Proc. Natl. Acad. Sci. U. S. A. 92:7996-8000.
15. Jarvis KG, Kaper JB. 1996. Secretion of extracellular proteins by entero-hemorrhagic Escherichia coli via a putative type III secretion system. Infect. Immun. 64:4826-4829.
16. Kenny B, Finlay BB. 1995. Protein secretion by enteropathogenic Esche-richia coli is essential for transducing signals to epithelial-cells. Proc. Natl. Acad. Sci. U. S. A. 92:7991-7995.
17. Wong AR, et al. 2011. Enteropathogenic and enterohaemorrhagic Esch-erichia coli: even more subversive elements. Mol. Microbiol. 80: 1420-1438.
18. Kenny B, et al. 1997. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 91:511-520.
19. Liu H, Magoun L, Luperchio S, Schauer DB, Leong JM. 1999. The tir-binding region of enterohaemorrhagic Escherichia coli intimin is sufficient to trigger actin condensation after bacterial-induced host cell signalling. Mol. Microbiol. 34:67-81.
20. Kenny B, et al. 2002. Co-ordinate regulation of distinct host cell signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules. Mol. Microbiol. 44:1095-1107.
21. Tu X, Nisan I, Yona C, Hanski E, Rosenshine I. 2003. EspH, a new cytoskeleton-modulating effector of enterohaemorrhagic and entero-pathogenic Escherichia coli. Mol. Microbiol. 47:595-606.
22. Papatheodorou P, et al. 2006. The enteropathogenic Escherichia coli (EPEC) map effector is imported into the mitochondrial matrix by the TOM/Hsp70 system and alters organelle morphology. Cell. Microbiol. 8:677-689.
23. Tobe T, et al. 2006. An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination. Proc. Natl. Acad. Sci. U. S. A. 103:14941-14946.
24. Kanack KJ, Crawford JA, Tatsuno I, Karmali MA, Kaper JB. 2005. SepZ/EspZ is secreted and translocated into HeLa cells by the entero-pathogenic Escherichia coli type III secretion system. Infect. Immun. 73: 4327-4337.
25. Crawford JA, Kaper JB. 2002. The N-terminus of enteropathogenic Esch-erichia coli (EPEC) tir mediates transport across bacterial and eukaryotic cell membranes. Mol. Microbiol. 46:855-868.
26. Shames SR, Croxen MA, Deng W, Finlay BB. 2011. The type III system-secreted effector EspZ localizes to host mitochondria and interacts with the translocase of inner mitochondrial membrane 17b. Infect. Immun. 79:4784-4790.
27. Phillips AD, Giròn J, Hicks S, Dougan G, Frankel G. 2000. Intimin from enteropathogenic Escherichia coli mediates remodelling of the eukaryotic cell surface. Microbiology 146:1333-1344.
28. Berger CN, Crepin VF, Jepson MA, Arbeloa A, Frankel G. 2009. The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics. Cell. Microbiol. 11:309-322.
29. Wong AR, Clements A, Raymond B, Crepin VF, Frankel G. 2012. The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH. mBio 3:e00250-11.
30. Charpentier X, Oswald E. 2004. Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescence-based reporter. J. Bacteriol. 186:5486-5495.
31. Wilharm G, et al. 2004. Yersinia enterocolitica type III secretion depends on the proton motive force but not on the flagellar motor components MotA and MotB. Infect. Immun. 72:4004-4009.
32. Schroeder GN, Jann NJ, Hilbi H. 2007. Intracellular type III secretion by cytoplasmic Shigella flexneri promotes caspase-1-dependent macrophage cell death. Microbiology 153:2862-2876.
33. Leopold SR, Shaikh N, Tarr PI. 2010. Further evidence of constrained radiation in the evolution of pathogenic Escherichia coli O157:H7. Infect. Genet. Evol. 10:1282-1285.
34. Creasey EA, Delahay RM, Daniell SJ, Frankel G. 2003. Yeast two-hybrid system survey of interactions between LEE-encoded proteins of enteropathogenic Escherichia coli. Microbiology 149:2093-2106.
35. Knutton S, et al. 1998. A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells. EMBO J. 17:2166-2176.
36. Wang D, Roe AJ, McAteer S, Shipston MJ, Gally DL. 2008. Hierarchal type III secretion of translocators and effectors from Escherichia coli O157:H7 requires the carboxy terminus of SepL that binds to tir. Mol. Microbiol. 69:1499-1512.
37. Elliott SJ, et al. 2002. A gene from the locus of enterocyte effacement that is required for enteropathogenic Escherichia coli to increase tight-junction permeability encodes a chaperone for EspF. Infect. Immun. 70: 2271-2277.
38. Thomas NA, et al. 2005. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli. Mol. Microbiol. 57:1762-1779.
39. Kubori T, Galán JE. 2003. Temporal regulation of salmonella virulence effector function by proteasome-dependent protein degradation. Cell 115:333-342.
40. Martinez E, et al. 2010. Binding to Na(+) /H(+) exchanger regulatory factor 2 (NHERF2) affects trafficking and function of the enteropathogenic Escherichia coli type III secretion system effectors map, EspI and NleH. Cell. Microbiol. 12:1718-1731.
41. Cisz M, Lee PC, Rietsch A. 2008. ExoS controls the cell contact-mediated switch to effector secretion in Pseudomonas aeruginosa. J. Bacteriol. 190: 2726-2738.
42. Mundy R, MacDonald TT, Dougan G, Frankel G, Wiles S. 2005. Citrobacter rodentium of mice and man. Cell. Microbiol. 7:1697-1706.
43. Holmström A, Rosqvist R, Wolf-Watz H, Forsberg A. 1995. Virulence plasmid-encoded YopK is essential for Yersinia pseudotuberculosis to cause systemic infection in mice. Infect. Immun. 63:2269-2276.
44. Holmström A, et al. 1997. YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane. Mol. Microbiol. 24:73-91.
45. Brodsky IE, et al. 2010. A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe 7:376-387.
46. Dewoody R, Merritt PM, Houppert AS, Marketon MM. 2011. YopK regulates the Yersiniapestis type III secretion system from within host cells. Mol. Microbiol. 79:1445-1461.
47. Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 97:6640-6645.
48. Schlosser-Silverman E, Elgrably-Weiss M, Rosenshine I, Kohen R, Altuvia S. 2000. Characterization of Escherichia coli DNA lesions generated within J774 macrophages. J. Bacteriol. 182:5225-5230.
49. Simpson N, et al. 2006. The enteropathogenic Escherichia coli type III secretion system effector map binds EBP50/NHERF1: implication for cell signalling and diarrhoea. Mol. Microbiol. 60:349-363.
50. Munera D, Crepin VF, Marches O, Frankel G. 2010. N-terminal type III secretion signal of enteropathogenic Escherichia coli translocator proteins. J. Bacteriol. 192:3534-3539.