Up-regulation of Heme oxygenase-1 attenuates brain damage after cerebral ischemia via simultaneous inhibition of superoxide production and preservation of NO bioavailability

Experimental Neurology

Volumn 239, Issue 1, 2013, Pages 163-169

  Chao, Xiaodong D ^a   Ma, Yihui H ^b   Luo, Peng ^b   Cao, Lei ^c   Lau, Wayne Bond ^e   Zhao, Baocheng C ^d   Han, Feng ^b   Liu, Wei ^b   Ning, Weidong D ^b   Su, Ning ^b   Zhang, Lei ^b   Zhu, Jie ^b   Fei, Zhou ^b   Qu, Yan ^b  

^a Xinjiang Military General Hospital   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^d The healthcare Department of General Political Department Hospital   (China)

^e THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

Heme oxygenase 1; MCAO; NOS; Oxidative nitrative stress

Indexed keywords

ADENOVIRUS VECTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROTOPORPHYRIN ZINC; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NITRATION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN ISCHEMIA; DEPENDOVIRUS; GENETIC THERAPY; GENETIC VECTORS; HEME OXYGENASE-1; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NERVOUS SYSTEM DISEASES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TYROSINE; UP-REGULATION;

EID: 84868331120     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.09.020     Document Type: Article

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