Potassium but not lactate dehydrogenase elevation due to in vitro hemolysis is higher in capillary than in venous blood samples

Archives of Pathology and Laboratory Medicine

Volumn 136, Issue 10, 2012, Pages 1262-1265

  Oostendorp, Marlies ^a   Van Solinge, Wouter ^a   Kemperman, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

LACTATE DEHYDROGENASE; POTASSIUM;

ADOLESCENT; ADULT; ARTICLE; BLOOD; BLOOD ANALYSIS; CAPILLARY; CHILD; HEMOLYSIS; HUMAN; STANDARD; VEIN;

ADOLESCENT; ADULT; BLOOD CHEMICAL ANALYSIS; CAPILLARIES; CHILD; HEMOLYSIS; HUMANS; L-LACTATE DEHYDROGENASE; POTASSIUM; VEINS; YOUNG ADULT;

EID: 84868329249     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: 10.5858/arpa.2011-0319-OA     Document Type: Article

References (20)

1. Lippi G, Blanckaert N, Bonini P, et al. Haemolysis: an overview of the leading cause of unsuitable specimens in clinical laboratories. Clin Chem Lab Med. 2008;46(6):764-772.
2. Scott M, LeGrys V, Klutts J. Electrolytes and blood gases. In: Burtis C, Ashwood E, Bruns D, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4th ed. St Louis, MO: Elsevier-Saunders; 2006:984.
3. Vermeer HJ, Steen G, Naus AJ, Goevaerts B, Agricola PT, Schoenmakers CH. Correction of patient results for Beckman Coulter LX-20 assays affected by interference due to hemoglobin, bilirubin or lipids: a practical approach. Clin Chem Lab Med. 2007;45(1):114-119.
4. Plebani M, Lippi G. Hemolysis index: quality indicator or criterion for sample rejection? Clin Chem Lab Med. 2009;47(8):899-902.
5. Brescia V, Tampoia M, Mileti A. Evaluation of factitious hyperkalemia in hemolytic samples: impact of the mean corpuscular hemoglobin concentration. LabMed. 2009;40:224-226.
6. Carraro P, Servidio G, Plebani M. Hemolyzed specimens: a reason for rejection or a clinical challenge? Clin Chem. 2000;46(2):306-307.
7. Dimeski G, Clague AE, Hickman PE. Correction and reporting of potassium results in haemolysed samples. Ann Clin Biochem. 2005;42(pt 2):119-123.
8. Hawkins R. Variability in potassium/hemoglobin ratios for hemolysis correction. Clin Chem. 2002;48(5):796.
9. Jay DW, Provasek D. Characterization and mathematical correction of hemolysis interference in selected Hitachi 717 assays. Clin Chem. 1993;39(9): 1804-1810.
10. Lippi G, Luca Salvagno G, Blanckaert N, et al. Multicenter evaluation of the hemolysis index in automated clinical chemistry systems. Clin Chem Lab Med. 2009;47(8):934-939.
11. Lippi G, Salvagno GL, Montagnana M, Brocco G, Guidi GC. Influence of hemolysis on routine clinical chemistry testing. Clin Chem Lab Med. 2006;44(3): 311-316.
12. Mansour MM, Azzazy HM, Kazmierczak SC. Correction factors for estimating potassium concentrations in samples with in vitro hemolysis: a detriment to patient safety. Arch Pathol Lab Med. 2009;133(6):960-966.
13. Meites S. Reproducibly simulating hemolysis, for evaluating its interference with chemical methods. Clin Chem. 1973;19(11):1319.
14. Owens H, Siparsky G, Bajaj L, Hampers LC. Correction of factitious hyperkalemia in hemolyzed specimens. Am J Emerg Med. 2005;23(7):872-875.
15. Steen G, Vermeer HJ, Naus AJ, Goevaerts B, Agricola PT, Schoenmakers CH. Multicenter evaluation of the interference of hemoglobin, bilirubin and lipids on Synchron LX-20 assays. Clin Chem Lab Med. 2006;44(4):413-419.
16. Demir AY, van Solinge WW, Kemperman H. Handling of and direct sampling from primary barcode-labeled pediatric tubes on Vitros clinical chemistry analyzers integrated into an enGen work cell. Clin Chem. 2005;51(5):920-921.
17. Kupke IR, Kather B, Zeugner S. On the composition of capillary and venous blood serum. Clin Chim Acta. 1981;112(2):177-185.
18. Johnson RM. Membrane stress increases cation permeability in red cells. Biophys J. 1994;67(5):1876-1881.
19. Jeffery J, Sharma A, Ayling RM. Detection of haemolysis and reporting of potassium results in samples from neonates. Ann Clin Biochem. 2009;46(pt 3): 222-225.
20. Lippi G, Ippolito L, Fontana R. Prevalence of hemolytic specimens referred for arterial blood gas analysis. Clin Chem Lab Med. 2011;49(5):931-932.