Diabetic HDL Is Dysfunctional in Stimulating Endothelial Cell Migration and Proliferation Due to Down Regulation of SR-BI Expression

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Pan, Bing ^a,b   Ma, Yijing ^a,b   Ren, Hui ^a,b   He, Yubin ^c   Wang, Yongyu ^d   Lv, Xiaofeng ^c   Liu, Donghui ^a,b   Ji, Liang ^a,b   Yu, Baoqi ^a,b   Wang, Yuhui ^a,b   Chen, Y Eugene ^e   Pennathur, Subramaniam ^e   Smith, Jonathan D ^f   Liu, George ^a,b   Zheng, Lemin ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Peking University Health Science Center   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

^d SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^e UNIVERSITY OF MICHIGAN   (United States)

^f LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN; PROTEIN KINASE B; SCAVENGER RECEPTOR BI;

ADULT; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; WILD TYPE;

ADULT; AGED; ANIMALS; AORTA; CELL MOVEMENT; CELL PROLIFERATION; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPROTEINS, HDL; MALE; MICE; MIDDLE AGED; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SCAVENGER RECEPTORS, CLASS B;

MUS;

EID: 84868327487     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048530     Document Type: Article

References (34)

1. Taskinen MR, (2003) Diabetic dyslipidaemia: from basic research to clinical practice. Diabetologia 46: 733-749.
2. Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, et al. (2007) HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. New England Journal of Medicine 357: 1301-1310.
3. Yamamoto S, Tanigawa H, Li X, Komaru Y, Billheimer JT, et al. (2011) Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport. Circulation 124: 1382-1390.
4. Terasaka N, Wang N, Yvan-Charvet L, Tall AR, (2007) High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. Proceedings of the National Academy of Sciences of the United States of America 104: 15093-15098.
5. Zhu W, Saddar S, Seetharam D, Chambliss KL, Longoria C, et al. (2008) The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity. Circ Res 102: 480-487.
6. Giannotti G, Doerries C, Mocharla PS, Mueller MF, Bahlmann FH, et al. (2010) Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: relation to endothelial dysfunction. Hypertension 55: 1389-1397.
7. Van Linthout S, Spillmann F, Riad A, Trimpert C, Lievens J, et al. (2008) Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy. Circulation 117: 1563-1573.
8. Patel S, Drew BG, Nakhla S, Duffy SJ, Murphy AJ, et al. (2009) Reconstituted high-density lipoprotein increases plasma high-density lipoprotein anti-inflammatory properties and cholesterol efflux capacity in patients with type 2 diabetes. J Am Coll Cardiol 53: 962-971.
9. Zheng L, Settle M, Brubaker G, Schmitt D, Hazen SL, et al. (2005) Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages. J Biol Chem 280: 38-47.
10. Nobecourt E, Jacqueminet S, Hansel B, Chantepie S, Grimaldi A, et al. (2005) Defective antioxidative activity of small dense HDL3 particles in type 2 diabetes: relationship to elevated oxidative stress and hyperglycaemia. Diabetologia 48: 529-538.
11. Sorrentino SA, Besler C, Rohrer L, Meyer M, Heinrich K, et al. (2010) Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy. Circulation 121: 110-122.
12. van Oostrom O, Nieuwdorp M, Westerweel PE, Hoefer IE, Basser R, et al. (2007) Reconstituted HDL increases circulating endothelial progenitor cells in patients with type 2 diabetes. Arterioscler Thromb Vasc Biol 27: 1864-1865.
13. Laight DW, Carrier MJ, Anggard EE, (1999) Endothelial cell dysfunction and the pathogenesis of diabetic macroangiopathy. Diabetes Metab Res Rev 15: 274-282.
14. Seetharam D, Mineo C, Gormley AK, Gibson LL, Vongpatanasin W, et al. (2006) High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I. Circ Res. 98: 63-72.
15. Tonello C, Zavan B, Cortivo R, Brun P, Panfilo S, et al. (2003) In vitro reconstruction of human dermal equivalent enriched with endothelial cells. Biomaterials 24: 1205-1211.
16. Chung BH, Wilkinson T, Geer JC, Segrest JP, (1980) Preparative and quantitative isolation of plasma lipoproteins: rapid, single discontinuous density gradient ultracentrifugation in a vertical rotor. Journal of Lipid Research 21: 284-291.
17. Hedrick CC, Thorpe SR, Fu MX, Harper CM, Yoo J, et al. (2000) Glycation impairs high-density lipoprotein function. Diabetologia 43: 312-320.
18. Valiyaveettil M, Kar N, Ashraf MZ, Byzova TV, Febbraio M, et al. (2008) Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI. Blood 111: 1962-1971.
19. Xu W, Xu L, Chen M, Mao YT, Xie ZG, et al. (2012) The effects of low dose X-irradiation on osteoblastic MC3T3-E1 Cells in Vitro. BMC Musculoskelet Disord 13: 94.
20. de Carvalho F, Costa ET, Camargo AA, Gregorio JC, Masotti C, et al. (2011) Targeting MAGE-C1/CT7 expression increases cell sensitivity to the proteasome inhibitor bortezomib in multiple myeloma cell lines. PLoS One 6: e27707.
21. Pan B, Ren H, Ma Y, Liu D, Yu B, et al. (2011) HDL of patients with type 2 diabetes mellitus elevates the capability of promoting migration and invasion of breast cancer cells. Int J Cancer.
22. Pan B, Ren H, He Y, Lv X, Ma Y, et al. (2012) HDL of Patients with Type 2 Diabetes Mellitus Elevates the Capability of Promoting Breast Cancer Metastasis. Clin Cancer Res.
23. Kimura T, Tomura H, Mogi C, Kuwabara A, Ishiwara M, et al. (2006) Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells. Cell Signal 18: 841-850.
24. Rohrer L, Ohnsorg PM, Lehner M, Landolt F, Rinninger F, et al. (2009) High-density lipoprotein transport through aortic endothelial cells involves scavenger receptor BI and ATP-binding cassette transporter G1. Circ Res 104: 1142-1150.
25. Matsunaga T, Nakajima T, Miyazaki T, Koyama I, Hokari S, et al. (2003) Glycated high-density lipoprotein regulates reactive oxygen species and reactive nitrogen species in endothelial cells. Metabolism 52: 42-49.
26. Xu Q, (2009) Disturbed flow-enhanced endothelial turnover in atherosclerosis. Trends Cardiovasc Med 19: 191-195.
27. Kawamoto A, Losordo DW, (2008) Endothelial progenitor cells for cardiovascular regeneration. Trends Cardiovasc Med 18: 33-37.
28. Tamagaki T, Sawada S, Imamura H, Tada Y, Yamasaki S, et al. (1996) Effects of high-density lipoproteins on intracellular pH and proliferation of human vascular endothelial cells. Atherosclerosis 123: 73-82.
29. Nobecourt E, Zeng J, Davies MJ, Brown BE, Yadav S, et al. (2008) Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I. Diabetologia 51: 1008-1017.
30. Murugesan G, Sa G, Fox PL, (1994) High-density lipoprotein stimulates endothelial cell movement by a mechanism distinct from basic fibroblast growth factor. Circ Res 74: 1149-1156.
31. Passarelli M, Tang C, McDonald TO, O'Brien KD, Gerrity RG, et al. (2005) Advanced glycation end product precursors impair ABCA1-dependent cholesterol removal from cells. Diabetes 54: 2198-2205.
32. Lam MC, Tan KC, Lam KS, (2004) Glycoxidized low-density lipoprotein regulates the expression of scavenger receptors in THP-1 macrophages. Atherosclerosis 177: 313-320.
33. Trigatti B, Rayburn H, Vinals M, Braun A, Miettinen H, et al. (1999) Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proc Natl Acad Sci U S A 96: 9322-9327.
34. Kimura T, Sato K, Malchinkhuu E, Tomura H, Tamama K, et al. (2003) High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors. Arteriosclerosis Thrombosis and Vascular Biology 23: 1283-1288.