Ppm1-Encoded Polyprenyl Monophosphomannose Synthase Activity Is Essential for Lipoglycan Synthesis and Survival in Mycobacteria

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Rana, Amrita K ^a   Singh, Albel ^a   Gurcha, Sudagar S ^a   Cox, Liam R ^a   Bhatt, Apoorva ^a   Besra, Gurdyal S ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN DERIVATIVE; GLYCOSYLTRANSFERASE; LIPOGLYCAN; LIPOMANNAN; MANNOSIDE; PHOSPHATIDYL MYOINOSITOL MANNOSIDE; POLYPRENYL MONOPHOSPHOMANNOSE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL SURVIVAL; BACTERIUM MUTANT; CARBOHYDRATE SYNTHESIS; ENZYME ACTIVITY; GENETIC COMPLEMENTATION; MSMEG3859 GENE; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; NONHUMAN; OPEN READING FRAME; PPGS GENE; PPM1 GENE; PROTEIN DEPLETION; RV3779 GENE;

BACTERIAL PROTEINS; GENES, ESSENTIAL; GENETIC COMPLEMENTATION TEST; LIPOPOLYSACCHARIDES; MANNOSYLTRANSFERASES; MICROBIAL VIABILITY; MYCOBACTERIUM SMEGMATIS; PHENOTYPE; SEQUENCE DELETION;

CORYNEBACTERINEAE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84868280204     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048211     Document Type: Article

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