Hect E3 ubiquitin ligase Tom1 controls Dia2 degradation during the cell cycle

Molecular Biology of the Cell

Volumn 23, Issue 21, 2012, Pages 4203-4211

  Kim, Dong Hwan ^a   Koepp, Deanna M ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

F BOX PROTEIN; PROTEIN DIA2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; GENE DELETION; GENE OVEREXPRESSION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN METABOLISM; PROTEIN STABILITY; PROTEIN TARGETING; TEMPERATURE SENSITIVITY; UBIQUITINATION;

AMINO ACIDS; CELL CYCLE; F-BOX PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

SACCHAROMYCETALES;

EID: 84868220709     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-07-0548     Document Type: Article

References (19)

1. Blake D, Luke B, Kanellis P, Jorgensen P, Goh T, Penfold S, Breitkreutz BJ, Durocher D, Peter M, Tyers M (2006). The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae. Genetics 174, 1709-1727. (Pubitemid 46011566)
2. Drury LS, Perkins G, Diffey JF (1997). The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J 16, 5966-5976. (Pubitemid 27427292)
3. Gelbart ME, Rechsteiner T, Richmond TJ, Tsukiyama T (2001). Interactions of Isw2 chromatin remodeling complex with nucleosomal arrays: analyses using recombinant yeast histones and immobilized templates. Mol Cell Biol 21, 2098-2106. (Pubitemid 32479631)
4. Iglesias N, Tutucci E, Gwizdek C, Vinciguerra P, Von Dach E, Corbett AH, Dargemont C, Stutz F (2010). Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export. Genes Dev 24, 1927-1938.
5. Kile AC, Koepp DM (2010). Activation of the S-phase checkpoint inhibits degradation of the F-box protein Dia2. Mol Cell Biol 30, 160-171.
6. Koepp DM, Kile AC, Swaminathan S, Rodriguez-Rivera V (2006). The F-box protein Dia2 regulates DNA replication. Mol Biol Cell 17, 1540-1548. (Pubitemid 44011574)
7. Kouranti I, Peyroche A (2012). Protein degradation in DNA damage response. Semin Cell Dev Biol 23, 538-545.
8. Kus BM, Caldon CE, Andorn-Broza R, Edwards AM (2004). Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins 54, 455-467. (Pubitemid 38197359)
9. Liu Q, Li MZ, Leibham D, Cortez D, Elledge SJ (1998). The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes. Curr Biol 8, 1300-1309. (Pubitemid 29006705)
10. Mimura S, Komata M, Kishi T, Shirahige K, Kamura T (2009). SCF (Dia2) regulates DNA replication forks during S-phase in budding yeast. EMBO J 28, 3693-3705.
11. Morohashi H, Maculins T, Labib K (2009). The amino-terminal TPR domain of Dia2 tethers SCF (Dia2) to the replisome progression complex. Curr Biol 19, 1943-1949.
12. Nakayama KI, Nakayama K (2006). Ubiquitin ligases: cell-cycle control and cancer. Nat Rev Cancer 6, 369-381.
13. Pan X, Ye P, Yuan DS, Wang X, Bader JS, Boeke JD (2006). A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124, 1069-1081. (Pubitemid 43344244)
14. Silverman JS, Skaar JR, Pagano M (2012). SCF ubiquitin ligases in the maintenance of genome stability. Trends Biochem Sci 37, 66-73.
15. Singh RK, Kabbaj MH, Paik J, Gunjan A (2009). Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis. Nat Cell Biol 11, 925-933.
16. Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW (1997). F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91, 209-219. (Pubitemid 27456388)
17. Swaminathan S, Kile AC, MacDonald EM, Koepp DM (2007). Yra1 is required for S phase entry and affects Dia2 binding to replication origins. Mol Cell Biol 27, 4674-4684. (Pubitemid 47016122)
18. Verma R, Feldman RM, Deshaies RJ (1997). SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities. Mol Biol Cell 8, 1427-1437. (Pubitemid 27385567)
19. Zhou P, Howley PM (1998). Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol Cell 2, 571-580. (Pubitemid 128379083)