A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and antioxidant status

Biochimie

Volumn 94, Issue 12, 2012, Pages 2723-2733

  Hemshekhar, M ^a   Sebastin Santhosh, M ^a   Sunitha, K ^a   Thushara, R M ^a   Kemparaju, K ^a   Rangappa, K S ^a   Girish, K S ^a  

^a UNIVERSITY OF MYSORE   (India)

Author keywords

Arthritis; Cartilage degradation; Hyaluronidases; Inflammatory mediators; Oxidative stress

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CATALASE; CATHEPSIN D; COLLAGENASE 3; CROCIN; CYCLOOXYGENASE 2; GELATINASE B; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLYCOSIDASE; HYALURONIDASE; HYDROGEN PEROXIDE; I KAPPA B; IBUPROFEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; STROMELYSIN; SUPEROXIDE DISMUTASE; THIOL; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; ARTICULAR CARTILAGE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARTILAGE; CARTILAGE DEGENERATION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOPATHOLOGY; INFLAMMATION; JOINT RADIOGRAPHY; LIPID PEROXIDATION; LIVER PROTECTION; NONHUMAN; OSTEOLYSIS; OXIDATIVE STRESS; RAT;

ACID PHOSPHATASE; ANIMALS; ANTIOXIDANTS; ARTHRITIS, EXPERIMENTAL; BLOTTING, WESTERN; BONE RESORPTION; CAROTENOIDS; CARTILAGE, ARTICULAR; CATHEPSIN D; CYTOKINES; DIETARY SUPPLEMENTS; GLUTATHIONE; HYALURONOGLUCOSAMINIDASE; INFLAMMATION; INFLAMMATION MEDIATORS; ISOENZYMES; LIVER; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 9; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

CROCUS SATIVUS;

EID: 84868215221     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.08.013     Document Type: Article

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