TRAIL-activated EGFR by Cbl-b-regulated EGFR redistribution in lipid rafts antagonises TRAIL-induced apoptosis in gastric cancer cells

European Journal of Cancer

Volumn 48, Issue 17, 2012, Pages 3288-3299

  Xu, Ling ^a   Zhang, Ye ^a   Liu, Jing ^a   Qu, Jinglei ^a   Hu, Xuejun ^a   Zhang, Fan ^a   Zheng, Huachuan ^a   Qu, Xiujuan ^a   Liu, Yunpeng ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Cbl b; EGFR; Lipid rafts; TRAIL

Indexed keywords

CASITAS B LINEAGE LYMPHOMA B; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; HUMAN; HUMAN CELL; LIPID RAFT; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; STOMACH CANCER;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CELL LINE, TUMOR; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; DRUG RESISTANCE, NEOPLASM; HUMANS; MEMBRANE MICRODOMAINS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTOR, EPIDERMAL GROWTH FACTOR; STOMACH NEOPLASMS; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84868211633     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.03.005     Document Type: Article

References (48)

1. A.D. Wagner, W. Grothe, and J. Haerting Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data J Clin Oncol 24 2006 2903 2909
2. I. Fraunholz, K. Grau, C. Weiss, and C. Rödel Patient- and treatment-related risk factors for nausea and emesis during concurrent chemoradiotherapy Strahlenther Onkol 187 2011 1 6
3. A. Sadarangani, S. Kato, and N. Espinoza TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract Apoptosis 12 2007 73 85
4. A.C. Bellail, M.C. Tse, and J.H. Song DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas J Cell Mol Med 14 2010 1303 1317
5. M. Gómez-Benito, M.J. Martinez-Lorenzo, A. Anel, I. Marzo, and J. Naval Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL Exp Cell Res 313 2007 2378 2388
6. J.H. Jang, T.J. Lee, and E.S. Yang Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1 Exp Cell Res 316 2010 2194 2203
7. J.W. Yu, P.D. Jeffrey, and Y. Shi Mechanism of procaspase-8 activation by c-FLIPL Proc Nat Acad Sci USA 106 2009 8169 8174
8. I.R. Cho, S.S. Koh, and H.J. Min Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation Int J Oncol 36 2010 1023 1030
9. L. Xu, X. Qu, and Y. Zhang Oxaliplatin enhances TRAIL-induced apoptosis in gastric cancer cells by CBL-regulated death receptor redistribution in lipid rafts FEBS Lett 583 2009 943 948
10. F.K. Braun, B. Hirsch, and N. Al-Yacoub Resistance of cutaneous anaplastic large-cell lymphoma cells to apoptosis by death ligands is enhanced by CD30-mediated overexpression of c-FLIP J Invest Dermatol 130 2010 826 840
11. S. Häcker, A. Dittrich, and A. Mohr Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8 Oncogene 28 2009 3097 3110
12. P. Li, S. Jayarama, and L. Ganesh Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4 J Biol Chem 285 2010 22713 22722
13. E. Peuhu, A. Rivero-Müller, and H. Stykki Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis Oncogene 29 2010 898 908
14. C. Gajate, F. Gonzalez-Camacho, and F. Mollinedo Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells PLoS One 4 2009 e5044
15. J.H. Song, M.C. Tse, and A. Bellail Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells Cancer Res 67 2007 6946 6955
16. M.O. Kinoshita, S. Furuya, and S. Ito Lipid rafts enriched in phosphatidylglucoside direct astroglial differentiation by regulating tyrosine kinase activity of epidermal growth factor receptors Biochem J 419 2009 565 575
17. Y. Liu, R. Sun, and W. Wan The involvement of lipid rafts in epidermal growth factor-induced chemotaxis of breast cancer cells Mol Membr Biol 24 2007 91 101
18. M.E. Irwin, K.L. Mueller, N. Bohin, Y. Ge, and J.L. Boerner Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib J Cell Physiol 226 2011 2316 2328
19. H.Y. Oh, E.J. Lee, and S. Yoon Cholesterol level of lipid raft microdomains regulates apoptotic cell death in prostate cancer cells through EGFR-mediated Akt and ERK signal transduction Prostate 67 2007 1061 1069
20. S. Van Schaeybroeck, D.M. Kelly, and J. Kyula Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAIL Cancer Res 68 2008 8312 8321
21. M. Shrader, M.S. Pino, and L. Lashinger Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression Cancer Res 67 2007 1430 1435
22. F. Teraishi, S. Kagawa, and T. Watanabe ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma FEBS Lett 579 2005 4069 4075
23. C. Krawczyk, K. Bachmaier, and T. Sasaki Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells Immunity 13 2000 463 473
24. X. Qu, S.M. Miah, and T. Hatani Selective inhibition of FcRI-mediated mast cell activation by a truncated variant of Cbl-b related to the rat model of type 1 diabetes mellitus J Biochem 137 2005 711 720
25. X. Qu, K. Sada, and S. Kyo Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b Blood 103 2004 1779 1786
26. E.M. Hur, Y.S. Park, and B.D. Lee Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains J Biol Chem 279 2004 5852 5860
27. X. Qu, Y. Zhang, and Y. Li Ubiquitin ligase Cbl-b sensitises leukemia and gastric cancer cells to anthracyclines by activating the mitochondrial pathway and modulating Akt and ERK survival signals FEBS Lett 583 2009 2255 2262
28. H. Malhi, and G.J. Gores TRAIL resistance results in cancer progression: a TRAIL to perdition? Oncogene 25 2006 7333 7335
29. O. Ndozangue-Touriguine, M. Sebbagh, and D. Mérino A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma Oncogene 27 2008 6012 6022
30. A. Hamaï, C. Richon, and F. Meslin Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: relationship to Bcl-2 family and caspase activation Oncogene 25 2006 7618 7634
31. F.H. Psahoulia, K.G. Drosopoulos, L. Doubravska, L. Andera, and A. Pintzas Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts Mol Cancer Ther 6 2007 2591 2599
32. C. Haag, D. Stadel, and S. Zhou Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells Gut 60 2011 225 237
33. V. Syed, K. Mukherjee, S. Godoy-Tundidor, and S.M. Ho Progesterone induces apoptosis in TRAIL-resistant ovarian cancer cells by circumventing c-FLIPL overexpression J Cell Biochem 102 2007 442 452
34. L.J. Pike Growth factor receptors, lipid rafts and caveolae: an evolving story Biochim Biophys Acta 1746 2005 260 273
35. N.J. Gibson, L.P. Tolbert, and L.A. Oland Roles of specific membrane lipid domains in EGF receptor activation and cell adhesion molecule stabilization in a developing olfactory system PLoS One 4 2009 e7222
36. G. Orr, D. Hu, and S. Ozçelik Cholesterol dictates the freedom of EGF receptors and HER2 in the plane of the membrane Biophys J 89 2005 1362 1373
37. S. Basu, S.K. Pathak, and G. Chatterjee Helicobacter pylori protein HP0175 transactivates epidermal growth factor receptor through TLR4 in gastric epithelial cells J Biol Chem 283 2008 32369 32376
38. Y. Zhang, X. Qu, and X. Hu Reversal of P-glycoprotein-mediated multi-drug resistance by the E3 ubiquitin ligase Cbl-b in human gastric adenocarcinoma cells J Pathol 218 2009 248 255
39. Y. Li, X. Qu, and J. Qu Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation Cancer Lett 284 2009 208 215
40. J.L. Qu, X.J. Qu, and M.F. Zhao The role of cbl family of ubiquitin ligases in gastric cancer exosome-induced apoptosis of Jurkat T cells Acta Oncol 48 2009 1173 1180
41. L. Duan, S.M. Raja, and G. Chen Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration J Biol Chem 286 2011 620 633
42. S.A. Ettenberg, Y.R. Rubinstein, and P. Banerjee Cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors Mol Cell Biol Res Commun 2 1999 111 118
43. S. Pennock, and Z. Wang A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation Mol Cell Biol 28 2008 3020 3037
44. J. Harding, and B. Burtness Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody Drugs Today (Barc) 41 2005 107 127
45. C.S. Karapetis, S. Khambata-Ford, and D.J. Jonker K-ras mutations and benefit from cetuximab in advanced colorectal cancer N Engl J Med 359 2008 1757 1765
46. E.M. Ibrahim, J.M. Zekri, and B.M. Bin Sadiq Cetuximab-based therapy for metastatic colorectal cancer: a meta-analysis of the effect of K-ras mutations Int J Colorectal Dis 25 2010 713 721
47. D. Liu, J. Jiang, and L. Zhang Metabolite characterization of a novel anti-cancer agent, icotinib, in humans through liquid chromatography/quadrupole time-of-flight tandem mass spectrometry Rapid Commun Mass Spectrum 25 2011 2131 2140
48. Z. Guan, X. Chen, Y. Wang, and D. Zhong Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry Rapid Commun Mass Spectrom 22 2008 2176 2184