Effects of isopropanol-isopropyl myristate binary enhancers on in vitro transport of estradiol in human epidermis: A mechanistic evaluation

Journal of Pharmaceutical Sciences

Volumn 98, Issue 2, 2009, Pages 565-572

  Liu, Puchun ^a,b   Cettina, Melinda ^a,c   Wong, Judy ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Biodel Inc   (United States)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

Binary enhancers; Estradiol; Isopropanol; Isopropyl myristate; Skin transport; Stratum corneum diffusivity; Stratum corneum solubility

Indexed keywords

2 PROPANOL; ESTRADIOL; GENTAMICIN; MYRISTIC ACID ISOPROPYL ESTER; PENETRATION ENHANCING AGENT; TRYPSIN; MYRISTIC ACID DERIVATIVE;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG SOLUBILITY; DRUG TRANSPORT; DRUG UPTAKE; EPIDERMIS; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; SKIN ABSORPTION; STRATUM CORNEUM; THERMODYNAMICS; BIOLOGICAL MODEL; CADAVER; DIFFUSION; DRUG EFFECT; KINETICS; METABOLISM; PERMEABILITY; SOLUBILITY;

2-PROPANOL; CADAVER; DIFFUSION; EPIDERMIS; ESTRADIOL; HUMANS; KINETICS; MODELS, BIOLOGICAL; MYRISTATES; PERMEABILITY; SKIN ABSORPTION; SOLUBILITY; THERMODYNAMICS;

EID: 59849090445     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21459     Document Type: Article

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