-
1
-
-
33747332544
-
Malignant melanoma: Genetics and therapeutics in the genomic era
-
Chin L, Garraway LA, Fisher DE,. Malignant melanoma: genetics and therapeutics in the genomic era. Genes Dev 2006; 20: 2149-82.
-
(2006)
Genes Dev
, vol.20
, pp. 2149-2182
-
-
Chin, L.1
Garraway, L.A.2
Fisher, D.E.3
-
2
-
-
66149090765
-
Molecular pathogenesis of cutaneous melanocytic neoplasms
-
Ibrahim N, Haluska FG,. Molecular pathogenesis of cutaneous melanocytic neoplasms. Annu Rev Pathol 2009; 4: 551-79.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 551-579
-
-
Ibrahim, N.1
Haluska, F.G.2
-
3
-
-
32844463799
-
The current epidemiology of cutaneous malignant melanoma
-
Berwick M, Wiggins C,. The current epidemiology of cutaneous malignant melanoma. Front Biosci 2006; 11: 1244-54.
-
(2006)
Front Biosci
, vol.11
, pp. 1244-1254
-
-
Berwick, M.1
Wiggins, C.2
-
4
-
-
84857017872
-
Epidemiology of invasive cutaneous melanoma
-
MacKie RM, Hauschild A, Eggermont AM,. Epidemiology of invasive cutaneous melanoma. Ann Oncol 2009; 20 (suppl 6): vi1-7.
-
(2009)
Ann Oncol
, vol.20
, Issue.SUPPL. 6
-
-
MacKie, R.M.1
Hauschild, A.2
Eggermont, A.M.3
-
5
-
-
74549179582
-
Sun and solarium exposure and melanoma risk: Effects of age, pigmentary characteristics, and nevi
-
Veierod MB, Adami HO, Lund E, et al. Sun and solarium exposure and melanoma risk: effects of age, pigmentary characteristics, and nevi. Cancer Epidemiol Biomarkers Prev 2010; 19: 111-20.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 111-120
-
-
Veierod, M.B.1
Adami, H.O.2
Lund, E.3
-
6
-
-
78049520359
-
Estimating the attributable fraction for melanoma: A meta-analysis of pigmentary characteristics and freckling
-
Olsen CM, Carroll HJ, Whiteman DC,. Estimating the attributable fraction for melanoma: a meta-analysis of pigmentary characteristics and freckling. Int J Cancer 2010; 127: 2430-45.
-
(2010)
Int J Cancer
, vol.127
, pp. 2430-2445
-
-
Olsen, C.M.1
Carroll, H.J.2
Whiteman, D.C.3
-
8
-
-
45549097424
-
ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma
-
Gudbjartsson DF, Sulem P, Stacey SN, et al. ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. Nat Genet 2008; 40: 886-91.
-
(2008)
Nat Genet
, vol.40
, pp. 886-891
-
-
Gudbjartsson, D.F.1
Sulem, P.2
Stacey, S.N.3
-
9
-
-
45549095449
-
Common sequence variants on 20q11.22 confer melanoma susceptibility
-
Brown KM, Macgregor S, Montgomery GW, et al. Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet 2008; 40: 838-40.
-
(2008)
Nat Genet
, vol.40
, pp. 838-840
-
-
Brown, K.M.1
MacGregor, S.2
Montgomery, G.W.3
-
10
-
-
67650073375
-
Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians
-
Nan H, Kraft P, Hunter DJ, et al. Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians. Int J Cancer 2009; 125: 909-17.
-
(2009)
Int J Cancer
, vol.125
, pp. 909-917
-
-
Nan, H.1
Kraft, P.2
Hunter, D.J.3
-
11
-
-
68149100807
-
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi
-
Falchi M, Bataille V, Hayward NK, et al. Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet 2009; 41: 915-9.
-
(2009)
Nat Genet
, vol.41
, pp. 915-919
-
-
Falchi, M.1
Bataille, V.2
Hayward, N.K.3
-
12
-
-
68149179663
-
Genome-wide association study identifies three loci associated with melanoma risk
-
Bishop DT, Demenais F, Iles MM, et al. Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet 2009; 41: 920-5.
-
(2009)
Nat Genet
, vol.41
, pp. 920-925
-
-
Bishop, D.T.1
Demenais, F.2
Iles, M.M.3
-
13
-
-
75549084094
-
Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma
-
Duffy DL, Zhao ZZ, Sturm RA, et al. Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma. J Invest Dermatol 2010; 130: 520-8.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 520-528
-
-
Duffy, D.L.1
Zhao, Z.Z.2
Sturm, R.A.3
-
14
-
-
80055002815
-
Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3
-
Macgregor S, Montgomery GW, Liu JZ, et al. Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nat Genet 2011; 43: 1114-8.
-
(2011)
Nat Genet
, vol.43
, pp. 1114-1118
-
-
MacGregor, S.1
Montgomery, G.W.2
Liu, J.Z.3
-
15
-
-
80054996042
-
Genome-wide association study identifies three new melanoma susceptibility loci
-
Barrett JH, Iles MM, Harland M, et al. Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet 2011; 43: 1108-13.
-
(2011)
Nat Genet
, vol.43
, pp. 1108-1113
-
-
Barrett, J.H.1
Iles, M.M.2
Harland, M.3
-
16
-
-
81855199793
-
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma
-
Amos CI, Wang LE, Lee JE, et al. Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet 2011; 20: 5012-23.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 5012-5023
-
-
Amos, C.I.1
Wang, L.E.2
Lee, J.E.3
-
17
-
-
33847188116
-
Melanocyte biology and skin pigmentation
-
Lin JY, Fisher DE,. Melanocyte biology and skin pigmentation. Nature 2007; 445: 843-50.
-
(2007)
Nature
, vol.445
, pp. 843-850
-
-
Lin, J.Y.1
Fisher, D.E.2
-
18
-
-
70349237926
-
Melanocortin receptor 1 variants and melanoma risk: A study of 2 European populations
-
Scherer D, Nagore E, Bermejo JL, et al. Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations. Int J Cancer 2009; 125: 1868-75.
-
(2009)
Int J Cancer
, vol.125
, pp. 1868-1875
-
-
Scherer, D.1
Nagore, E.2
Bermejo, J.L.3
-
19
-
-
77956190317
-
Genetics of pigmentation in skin cancera - A review
-
Scherer D, Kumar R,. Genetics of pigmentation in skin cancera-a review. Mutat Res 2010; 705: 141-53.
-
(2010)
Mutat Res
, vol.705
, pp. 141-153
-
-
Scherer, D.1
Kumar, R.2
-
20
-
-
45549095745
-
Two newly identified genetic determinants of pigmentation in Europeans
-
Sulem P, Gudbjartsson DF, Stacey SN, et al. Two newly identified genetic determinants of pigmentation in Europeans. Nat Genet 2008; 40: 835-7.
-
(2008)
Nat Genet
, vol.40
, pp. 835-837
-
-
Sulem, P.1
Gudbjartsson, D.F.2
Stacey, S.N.3
-
21
-
-
79955783356
-
ASIP genetic variants and the number of non-melanoma skin cancers
-
Lin W, Qureshi AA, Kraft P, et al. ASIP genetic variants and the number of non-melanoma skin cancers. Cancer Causes Control 2011; 22: 495-501.
-
(2011)
Cancer Causes Control
, vol.22
, pp. 495-501
-
-
Lin, W.1
Qureshi, A.A.2
Kraft, P.3
-
22
-
-
84860700714
-
MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas
-
Helsing P, Nymoen DA, Rootwelt H, et al. MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. Genes Chromosomes Cancer 2012; 51: 654-61.
-
(2012)
Genes Chromosomes Cancer
, vol.51
, pp. 654-661
-
-
Helsing, P.1
Nymoen, D.A.2
Rootwelt, H.3
-
23
-
-
0035999728
-
Agouti: From mouse to man, from skin to fat
-
Voisey J, van Daal A,. Agouti: from mouse to man, from skin to fat. Pigment Cell Res 2002; 15: 10-8.
-
(2002)
Pigment Cell Res
, vol.15
, pp. 10-18
-
-
Voisey, J.1
Van Daal, A.2
-
24
-
-
0038814297
-
Agouti signal protein regulation in human melanoma cells
-
Voisey J, Kelly G, Van Daal A,. Agouti signal protein regulation in human melanoma cells. Pigment Cell Res 2003; 16: 65-71.
-
(2003)
Pigment Cell Res
, vol.16
, pp. 65-71
-
-
Voisey, J.1
Kelly, G.2
Van Daal, A.3
-
25
-
-
21244446712
-
MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population
-
Landi MT, Kanetsky PA, Tsang S, et al. MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population. J Natl Cancer Inst 2005; 97: 998-1007.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 998-1007
-
-
Landi, M.T.1
Kanetsky, P.A.2
Tsang, S.3
-
26
-
-
0036181358
-
A polymorphism in the agouti signaling protein gene is associated with human pigmentation
-
Kanetsky PA, Swoyer J, Panossian S, et al. A polymorphism in the agouti signaling protein gene is associated with human pigmentation. Am J Hum Genet 2002; 70: 770-5.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 770-775
-
-
Kanetsky, P.A.1
Swoyer, J.2
Panossian, S.3
-
27
-
-
20244369752
-
The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color in African Americans
-
Bonilla C, Boxill LA, Donald SA, et al. The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color in African Americans. Hum Genet 2005; 116: 402-6.
-
(2005)
Hum Genet
, vol.116
, pp. 402-406
-
-
Bonilla, C.1
Boxill, L.A.2
Donald, S.A.3
-
28
-
-
58249125574
-
The contribution of melanocortin 1 receptor gene polymorphisms and the agouti signalling protein gene 8818A>G polymorphism to cutaneous melanoma and basal cell carcinoma in a Polish population
-
Brudnik U, Branicki W, Wojas-Pelc A, et al. The contribution of melanocortin 1 receptor gene polymorphisms and the agouti signalling protein gene 8818A>G polymorphism to cutaneous melanoma and basal cell carcinoma in a Polish population. Exp Dermatol 2009; 18: 167-74.
-
(2009)
Exp Dermatol
, vol.18
, pp. 167-174
-
-
Brudnik, U.1
Branicki, W.2
Wojas-Pelc, A.3
-
29
-
-
65549148775
-
Clinical and epidemiologic profile of melanoma patients according to sun exposure of the tumor site
-
Nagore E, Botella-Estrada R, Requena C, et al. Clinical and epidemiologic profile of melanoma patients according to sun exposure of the tumor site. Actas Dermosifiliogr 2009; 100: 205-11.
-
(2009)
Actas Dermosifiliogr
, vol.100
, pp. 205-211
-
-
Nagore, E.1
Botella-Estrada, R.2
Requena, C.3
-
30
-
-
52249113326
-
Comparison between familial and sporadic cutaneous melanoma in Valencia, Spain
-
Nagore E, Botella-Estrada R, Garcia-Casado Z, et al. Comparison between familial and sporadic cutaneous melanoma in Valencia, Spain. J Eur Acad Dermatol Venereol 2008; 22: 931-6.
-
(2008)
J Eur Acad Dermatol Venereol
, vol.22
, pp. 931-936
-
-
Nagore, E.1
Botella-Estrada, R.2
Garcia-Casado, Z.3
-
31
-
-
58249103106
-
Acral lentiginous melanoma presents distinct clinical profile with high cancer susceptibility
-
Nagore E, Pereda C, Botella-Estrada R, et al. Acral lentiginous melanoma presents distinct clinical profile with high cancer susceptibility. Cancer Causes Control 2009; 20: 115-9.
-
(2009)
Cancer Causes Control
, vol.20
, pp. 115-119
-
-
Nagore, E.1
Pereda, C.2
Botella-Estrada, R.3
-
32
-
-
0035881074
-
Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma
-
Balch CM, Buzaid AC, Soong SJ, et al. Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 2001; 19: 3635-48.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3635-3648
-
-
Balch, C.M.1
Buzaid, A.C.2
Soong, S.J.3
-
33
-
-
80051959840
-
Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma
-
Chatzinasiou F, Lill CM, Kypreou K, et al. Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma. J Natl Cancer Inst 2011; 103: 1227-35.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1227-1235
-
-
Chatzinasiou, F.1
Lill, C.M.2
Kypreou, K.3
-
34
-
-
84857192750
-
HERC2 rs12913832 modulates human pigmentation by attenuating chromatin loop formation between a long-range enhancer and the OCA2 promoter
-
Visser M, Kayser M, Palstra RJ,. HERC2 rs12913832 modulates human pigmentation by attenuating chromatin loop formation between a long-range enhancer and the OCA2 promoter. Genome Res 2012; 22: 446-55.
-
(2012)
Genome Res
, vol.22
, pp. 446-455
-
-
Visser, M.1
Kayser, M.2
Palstra, R.J.3
-
35
-
-
68149170044
-
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
-
Tuupanen S, Turunen M, Lehtonen R, et al. The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nat Genet 2009; 41: 885-90.
-
(2009)
Nat Genet
, vol.41
, pp. 885-890
-
-
Tuupanen, S.1
Turunen, M.2
Lehtonen, R.3
-
36
-
-
0033607672
-
A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo
-
Lee SK, Anzick SL, Choi JE, et al. A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. J Biol Chem 1999; 274: 34283-93.
-
(1999)
J Biol Chem
, vol.274
, pp. 34283-34293
-
-
Lee, S.K.1
Anzick, S.L.2
Choi, J.E.3
-
37
-
-
0034465051
-
Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2
-
Lee SK, Na SY, Jung SY, et al. Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2. Mol Endocrinol 2000; 14: 915-25.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 915-925
-
-
Lee, S.K.1
Na, S.Y.2
Jung, S.Y.3
-
38
-
-
0037160140
-
Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality
-
Kuang SQ, Liao L, Zhang H, et al. Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality. J Biol Chem 2002; 277: 45356-60.
-
(2002)
J Biol Chem
, vol.277
, pp. 45356-45360
-
-
Kuang, S.Q.1
Liao, L.2
Zhang, H.3
-
39
-
-
0344442711
-
Interaction and functional cooperation of the cancer-amplified transcriptional coactivator activating signal cointegrator-2 and E2F-1 in cell proliferation
-
Kong HJ, Yu HJ, Hong S, et al. Interaction and functional cooperation of the cancer-amplified transcriptional coactivator activating signal cointegrator-2 and E2F-1 in cell proliferation. Mol Cancer Res 2003; 1: 948-58.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 948-958
-
-
Kong, H.J.1
Yu, H.J.2
Hong, S.3
-
40
-
-
41649116321
-
Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development
-
Mahajan MA, Samuels HH,. Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development. Nucl Recept Signal 2008; 6: e002.
-
(2008)
Nucl Recept Signal
, vol.6
-
-
Mahajan, M.A.1
Samuels, H.H.2
-
41
-
-
66649120472
-
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
-
Lee J, Kim DH, Lee S, et al. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad Sci USA 2009; 106: 8513-8.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8513-8518
-
-
Lee, J.1
Kim, D.H.2
Lee, S.3
-
42
-
-
70349766918
-
ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity
-
Kim DH, Lee J, Lee B, et al. ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity. Mol Endocrinol 2009; 23: 1556-62.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1556-1562
-
-
Kim, D.H.1
Lee, J.2
Lee, B.3
-
43
-
-
0037388853
-
Spatial distribution of the messenger ribonucleic acid and protein of the nuclear receptor coactivator, amplified in breast cancer-3, in mice
-
Zhang H, Liao L, Kuang SQ, et al. Spatial distribution of the messenger ribonucleic acid and protein of the nuclear receptor coactivator, amplified in breast cancer-3, in mice. Endocrinology 2003; 144: 1435-43.
-
(2003)
Endocrinology
, vol.144
, pp. 1435-1443
-
-
Zhang, H.1
Liao, L.2
Kuang, S.Q.3
-
44
-
-
11144356842
-
CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer
-
Guo Z, Linn JF, Wu G, et al. CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer. Nat Med 2004; 10: 374-81.
-
(2004)
Nat Med
, vol.10
, pp. 374-381
-
-
Guo, Z.1
Linn, J.F.2
Wu, G.3
-
45
-
-
38049147787
-
MEF2: A central regulator of diverse developmental programs
-
Potthoff MJ, Olson EN,. MEF2: a central regulator of diverse developmental programs. Development 2007; 134: 4131-40.
-
(2007)
Development
, vol.134
, pp. 4131-4140
-
-
Potthoff, M.J.1
Olson, E.N.2
-
46
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009; 461: 747-53.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
47
-
-
77954407332
-
Genomewide association studies and assessment of the risk of disease
-
Manolio TA,. Genomewide association studies and assessment of the risk of disease. N Engl J Med 2010; 363: 166-76.
-
(2010)
N Engl J Med
, vol.363
, pp. 166-176
-
-
Manolio, T.A.1
-
48
-
-
79951473520
-
9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response
-
Harismendy O, Notani D, Song X, et al. 9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response. Nature 2011; 470: 264-8.
-
(2011)
Nature
, vol.470
, pp. 264-268
-
-
Harismendy, O.1
Notani, D.2
Song, X.3
-
49
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson W, Liang L, Abecasis G, et al. Mapping complex disease traits with global gene expression. Nat Rev Genet 2009; 10: 184-94.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
-
50
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
-
Nicolae DL, Gamazon E, Zhang W, et al. Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet 2010; 6: e1000888.
-
(2010)
PLoS Genet
, vol.6
-
-
Nicolae, D.L.1
Gamazon, E.2
Zhang, W.3
|