Ethanol disinfection affects physical properties and cell response of electrospun poly(l-lactic acid) scaffolds

European Polymer Journal

Volumn 48, Issue 12, 2012, Pages 2008-2018

  Gualandi, Chiara ^a   Govoni, Marco ^a,b   Foroni, Laura ^a   Valente, Sabrina ^a   Bianchi, Michele ^c,d   Giordano, Emanuele ^a,b   Pasquinelli, Gianandrea ^a   Biscarini, Fabio ^c   Focarete, Maria Letizia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c CNR   (Italy)

^d RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

Crystallinity; Electrospinning; H9c2 cells; Polylactic acid; Sterilization

Indexed keywords

AMORPHOUS FIBERS; CELL LINES; CELL MOTILITY; CELL RESPONSE; CRYSTAL PHASE; CRYSTALLINITIES; ELECTROSPUN MATERIALS; ELECTROSPUNS; FIBER MORPHOLOGY; H9C2 CELLS; PLLA; POLY L LACTIC ACID; POLY LACTIC ACID; SCAFFOLD PROPERTIES; SEMICRYSTALLINES; SOAKING TIME; SYSTEMATIC INVESTIGATIONS; THERMOMECHANICAL PROPERTIES;

BIOMECHANICS; CELL ADHESION; CELL CULTURE; DISINFECTION; ELECTROSPINNING; ETHANOL; FIBERS; LACTIC ACID; MECHANICAL PROPERTIES; SPINNING (FIBERS); STERILIZATION (CLEANING);

SCAFFOLDS (BIOLOGY);

EID: 84868205826     PISSN: 00143057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpolymj.2012.09.016     Document Type: Article

References (56)

1. S. Agarwal, J.H. Wendorff, and A. Greiner Use of electrospinning technique for biomedical applications Polymer 49 2008 5603 5621
2. A. Szentivanyi, T. Chakradeo, H. Zernetsch, and B. Glasmacher Electrospun cellular microenvironments: understanding controlled release and scaffold structured Adv Drug Deliv Rev 63 2011 209 220
3. E.-R. Kenawi, J.M. Layman, J.R. Watkins, G.L. Bowlin, J.A. Matthews, and D. Simpson Electrospinning of poly(ethylene-co-vinyl alcohol) fibers Biomaterials 24 2003 907 913 (Pubitemid 36024168)
4. E.-R. Kenawi, F.I. Abdel-Hay, M.H. El-Newehy, and G.E. Wnek Processing of polymer nanofibers through electrospinning as drug delivery systems Mater Chem Phys 113 2009 296 302
5. K.-L. Ou, C.-S. Chen, L.-H. Lin, J.-C. Lu, Y.-C. Shu, and W.-C. Tseng Membranes of epitaxial-like packed, super aligned electrospun micron hollow poly(l-lactic acid) (PLLA) fibers Eur Polym J 47 2011 882 892
6. M.L. Focarete, C. Gualandi, and L. Moroni Working with electrospun scaffolds: some practical hints for tissue engineers A.K. Haghi, Electrospun nanofibers research: recent developments 2009 Nova Science Publisher Hauppauge (NY) 19 34
7. K.A. Athanasiou, G.G. Niederauer, and C.M. Agrawal Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers Biomaterials 17 1996 93 102 (Pubitemid 26031365)
8. C.E. Holy, C. Cheng, J.E. Davies, and M.S. Shoichet Optimizing the sterilization of PLGA scaffolds for use in tissue engineering Biomaterials 22 2001 25 31
9. K.D. Andrews, J.A. Hunt, and R.A. Black Effects of sterilisation method on surface topography and in-vitro cell behaviour of electrostatically spun scaffolds Biomaterials 28 2007 1014 1026 (Pubitemid 44809414)
10. A. Rainer, M. Centola, C. Spadacio, G. Gherardi, J.A. Genovese, and S. Licoccia Comparative study of different techniques for the sterilization of poly-l-lactide electrospun microfibers: effectiveness vs. material degradation Int J Artif Organs 33 2010 76 85
11. M. Selim, A.J. Bullock, K.A. Blackwood, C.R. Chapple, and S. MacNeil Developing biodegradable scaffolds for tissue engineering of the urethra Br J Urol Int 107 2010 296 302
12. D. Yixiang, T. Yong, S. Liao, C.K. Chan, and S. Ramakrishna Degradation of electrospun nanofiber scaffold by short wave length ultraviolet radiation treatment and its potential applications in tissue engineering Tissue Eng A 14 2008 1321 1329
13. S.I. Jeong, S.Y. Kim, S.K. Cho, M.S. Chong, K.S. Kim, and H. Kim Tissue-engineered vascular grafts composed of marine collagen and PLGA fibers using pulsatile perfusion bioreactors Biomaterials 28 2007 1115 1122 (Pubitemid 44809424)
14. L.A. Smith, X. Liu, J. Hu, and P.X. Ma The influence of three-dimensional nanofibrous scaffolds on the osteogenic differentiation of embryonic stem cells Biomaterials 30 2009 2516 2522
15. J. Xie, S.M. Willerth, X. Li, M.R. Macewan, A. Rader, and S.E. Sakiyama-Elbert The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages Biomaterials 30 2009 354 362
16. S. Torres-Giner, J.V. Gimeno-Alcaniz, M.J. Ocio, and J.M. Lagaron Optimization of electrospun polylactide-based ultrathin fibers for osteoconductive bone scaffolds J Appl Polym Sci 122 2011 914 925
17. A.S. Badami, M.R. Kreke, M.S. Thompson, J.S. Riffle, and A.S. Goldstein Effect of fiber diameter on spreading, proliferation and differentiation of osteoblastic cells on electrospun poly(lactic acid) substrates Biomaterials 27 2006 596 606 (Pubitemid 41464255)
18. X. Zhu, W. Cui, X. Li, and Y. Jin Electrospun fibrous mats with high porosity as potential scaffolds for skin tissue engineering Biomacromolecules 9 2008 1795 1801
19. W.J. Li, R. Tuli, C. Okafor, A. Derfoul, K.G. Danielson, and D.J. Hall A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells Biomaterials 26 2005 599 609 (Pubitemid 38988302)
20. N. Takeuchi, M. Machigashira, D. Yamashita, Y. Shirakata, T. Kasuga, and K. Noguchi Cellular compatibility of a gamma-irradiated modified siloxane-poly(lactic acid)-calcium carbonate hybrid membrane for guided bone regeneration Dent Mater J 30 2011 730 738
21. A.G. Mikos, M.D. Lyman, L.E. Freed, and R. Langer Wetting of poly(l-lactic acid) and poly(d, l-lactic-co-glycolic acid) foams for tissue culture Biomaterials 15 1994 55 58
22. B.M. Baker, and R.L. Mauck The effect of nanofiber alignment on the maturation of engineered meniscus constructs Biomaterials 28 2007 1967 1977 (Pubitemid 46176172)
23. F. Peng, X. Yu, and M. Wei In vitro cell performances on hydroxyapatite particles/poly(l-lactic acid) nanofibrous scaffolds with an excellent particle along nanofiber orientation Acta Biomater 7 2011 2585 2592
24. X. Zhang, C.B. Baughman, and D.L. Kaplan In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth Biomaterials 29 2008 2217 2227
25. O. Hartman, C. Zhang, E.L. Adams, M.C. Farach-Carson, N.J. Petrelli, and B.D. Chase Microfabricated electrospun collagen membranes for 3-D cancer models and drug screening applications Biomacromolecules 10 2009 2019 2032
26. T. Andric, A.C. Sampson, and J.W. Freeman Fabrication and characterization of electrospun osteon mimicking scaffolds for bone tissue engineering Mater Sci Eng C 31 2011 2 8
27. J. Guan, K.L. Fujimoto, M.S. Sacks, and W.R. Wagner Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications Biomaterials 26 2005 3961 3971 (Pubitemid 40038787)
28. E.J. Chong, T.T. Phan, I.J. Lim, Y.Z. Zhang, B.H. Bay, and S. Ramakrishna Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstruction Acta Biomater 3 2007 321 330 (Pubitemid 46555131)
29. C. Erisken, D.M. Kalyon, and H. Wang Functionally graded electrospun polycaprolactone and β-tricalcium phosphate nanocomposites for tissue engineering applications Biomaterials 29 2008 4065 4073
30. S.H. Ku, and C.B. Park Human endothelial cell growth on mussel-inspired nanofiber scaffold for vascular tissue engineering Biomaterials 31 2010 9431 9437
31. A. Thorvaldsson, H. Stenhamre, P. Gatenholm, and P. Walkenström Electrospinning of highly porous scaffolds for cartilage regeneration Biomacromolecules 9 2008 1044 1049 (Pubitemid 351560500)
32. S. Zhong, W.E. Teo, X. Zhu, R.W. Beuerman, S. Ramakrishna, and L.Y. Yung An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture J Biomed Mater Res 79A 2006 456 463 (Pubitemid 44845158)
33. X.Y. Xu, X.T. Li, S.W. Peng, J.F. Xiao, C. Liu, and G. Fang The behaviour of neural stem cells on polyhydroxyalkanoate nanofiber scaffolds Biomaterials 31 2010 3967 3975
34. C. Huang, R. Chen, Q. Ke, Y. Morsi, K. Zhang, and X. Mo Electrospun collagen-chitosan-TPU nanofibrous scaffolds for tissue engineered tubular grafts Colloid Surf B: Bionterfaces 82 2011 307 315
35. Z. Ma, F. Chen, Y.J. Zhu, T. Cui, and X.Y. Liu Amorphous calcium phosphate/poly(d, l-lactic acid) composite nanofibers: electrospinning preparation and biomineralization J Colloid Interface Sci 359 2011 371 379
36. H.S. Koh, T. Yong, C.K. Chan, and S. Ramakrishna Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin Biomaterials 29 2008 3574 3582
37. J.D. Stitzel, K.J. Pawlowski, G.E. Wnek, D.G. Simpson, and G.L. Bowlin Arterial smooth muscle cell proliferation on a novel biomimicking, biodegradable vascular graft scaffold J Biomater Appl 16 2001 22 33 (Pubitemid 32715435)
38. E. Schnell, K. Klinkhammer, S. Balzer, G. Brook, D. Klee, and P. Dalton Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly - caprolactone and a collagen/poly - caprolactone blend Biomaterials 28 2007 3012 3025 (Pubitemid 46560871)
39. B.S. Jha, R.J. Colello, J.R. Bowman, S.A. Sell, K.D. Lee, and J.W. Bigbee Two pole air gap electrospinning: fabrication of highly aligned, three-dimensional scaffolds for nerve reconstruction Acta Biomater 7 2011 203 215
40. M. Govoni, F. Bonavita, L.M. Shantz, C. Guarnieri, and E. Giordano Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts Amino Acids 38 2010 541 547
41. R. Inai, M. Kotaki, and S. Ramakrishna Structure and properties of electrospun PLLA single nanofibres Nanotechnology 16 2005 208 213 (Pubitemid 40274846)
42. X. Zhong, K. Kim, D. Fang, S. Ran, B.S. Hsiao, and B. Chu Structure and process relationship of electrospun bioabsorbable nanofiber membranes Polymer 43 2002 4403 4412 (Pubitemid 34619697)
43. D. Garlotta A literature review of poly(lactic acid) J Polym Environ 9 2001 63 84
44. X. Zong, S. Ran, K.-S. Kim, D. Fang, B.S. Hsiao, and B. Chu Structure and morphology changes during in vitro degradation of electrospun poly(glycolide-co-lactide) nanofiber membrane Biomacromolecules 4 2003 416 423 (Pubitemid 36527115)
45. D.C. Surrao, J.W.S. Hayami, S.D. Waldman, and B.G. Amsen Self-crimping, biodegradable, electrospun polymer microfibers Biomacromolecules 11 2010 3624 3629
46. N. Naga, Y. Yoshida, M. Inui, K. Noguchi, and S. Murase Crystallization of amorphous poly(lactic acid) induced by organic solvents J Appl Polym Sci 119 2011 2058 2064
47. C. Marega, A. arigo, V. Di Noto, and R. Zannetti Structure and crystallization kinetics of poly(l-lactic acid) Die Makromol Chem 193 1992 1599 1606
48. N.R. Washburn, K.M. Yamada, C.G. Simon, S.B. Kennedy, and E.J. Amis High-throughput investigation of osteoblast response to polymer crystallinity: influence of nanometer-scale roughness on proliferation Biomaterials 25 2004 1215 1224 (Pubitemid 37476199)
49. X. Wei, Z. Xia, S.-C. Wong, and A. Baji Modelling of mechanical properties of electrospun nanofibre network Int J Exp Comput Biomech 1 2009 45 57
50. G. Perego, G.D. Cella, and C. Bastioli Effect of molecular weight and crystallinity on poly(lactic acid) mechanical properties J Appl Polym Sci 59 1996 37 43 (Pubitemid 126627915)
51. E.P.S. Tan, and C.T. Lim Effects of annealing on the structural and mechanical properties of electrospun polymeric nanofibres Nanotechnology 17 2006 2649 2654 (Pubitemid 43745805)
52. V. Vogel, and M. Sheetz Local force and geometry sensing regulate cell functions Nat Rev Mol Cell Biol 7 2006 265 275
53. C.J. Bettinger, R. Langer, and J.T. Borenstein Engineering substrate topography at the micro- and nanoscale to control cell function Angew Chem Int Ed 48 2009 5406 5415
54. A. Park, and L.G. Cima In vitro cell response to differences in poly-l-lactide crystallinity J Biomed Mater Res A 31 1996 117 130 (Pubitemid 26125311)
55. S. Zhong, Y. Zhang, and C.T. Lim Fabrication of large pores in electrospun nanofibrous scaffolds for cellular infiltration: a review Tissue Eng B: Rev 18 2012 77 87
56. D. Ilic, C.H. Damsky, and T. Yamamoto Focal adhesion kinase: at the crossroads of signal transduction J Cell Sci 110 1997 401 407 (Pubitemid 27116721)