Pulmonary expression of nitric oxide synthase isoforms in sheep with smoke inhalation and burn injury

Experimental Lung Research

Volumn 35, Issue 2, 2009, Pages 104-118

  Cox, Robert A ^a   Jacob, Sam ^a   Oliveras, Gloria ^a   Murakami, Kazunori ^b   Enkhbaatar, Perenlei ^b   Traber, Lillian ^b   Schmalstieg, Frank C ^b   Herndon, David N ^a   Traber, Daniel L ^b   Hawkins, Hal K ^a  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Acute lung injury; Airway; Immunohistochemistry; Lung; Mucous glands; Nitric oxide; Nitric oxide isoforms; Sheep

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE;

ACUTE LUNG INJURY; AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; LUNG ALVEOLUS MACROPHAGE; LUNG BURN; LUNG ENDOTHELIUM; LUNG PARENCHYMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEEP;

ANIMALS; BRONCHI; BURNS; EPITHELIUM; FEMALE; KINETICS; LUNG; MACROPHAGES; MODELS, ANIMAL; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RESPIRATORY MUCOSA; SHEEP; SMOKE INHALATION INJURY; TISSUE DISTRIBUTION;

EID: 61949113696     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140802446832     Document Type: Article

References (45)

1. Shirani KZ, Pruitt BA, Mason AD Jr: The influence of and pneumonia on burn mortality. Ann Surg. 1987;205:82-87.
2. Herndon DN, Traber DL, Niehaus GD, Linares HA, Traber, LD: The pathophysiology of smoke inhalation injury in sheep model. J Trauma. 1984;24:1044-1051.
3. Basadre JO, Sugi K, Traber DL, Traber LD: The effect of leukocyte depletion on smoke inhalation injury in sheep. Surgery. 1988;104:208-215.
4. Enkhbaatar P, Murakami K, Shimoda K, Mizutani A, Traber L, Phillips GB, Parkinson JF, Cox R, Hawkins H, Herndon D, Traber D: The inducible nitric oxide synthase inhibitor BBS-2 prevents acute lung injury in sheep after burn and smoke inhalation injury. Am J Respir Crit Care Med. 2003;167:1021-1026.
5. Soejima K, McGuire R, Snyder N, Uchida T, Szabo C, Salzman A, Traber LD, Traber DL: The effect of inducible nitric oxide synthase (iNOS) inhibition on smoke inhalation injury in sheep. Shock. 2000;13:261-266.
6. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA: Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci U S A. 1990;87:1620-1624.
7. Ischiropoulos H, Zhu L, Chen J., Tsai M, Martin JC, Smith CD, Beckman JS: Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys. 1992;298:431-437.
8. Schiffrin EL, Touyz RM: Vascular biology of endothelin. J Cardiovasc Pharmacol. 1998;32(Suppl 3):S2-S13.
9. Stroes ES, van Faassen EE, van Londen GJ, Rabelink TJ: Oxygen radical stress in vascular disease: the role of endothelial nitric oxide synthase. J Cardiovasc Pharmacol. 1998;32(Suppl 3):S14-S21.
10. Royall JA, Kooy NW, Beckman JS: Nitric oxide-related oxidants in acute lung injury. New Horiz. 1995;3:113-122.
11. Tassiopoulos AK, Hakim TS, Finck CM, Pedoto A, Hodell MG, Landas SK, McGraw DJ: Neutrophil sequestration in the lung following acute aortic occlusion starts during ischaemia and can be attenuated by tumour necrosis factor and nitric oxide blockade. Eur J Vasc Endovasc Surg. 1998;16:36-42.
12. G-monomethyl-l-arginine: a role for cyclic GMP. Blood. 1989;74:1885-1887.
13. de Mello SB, Novaes GS, Laurindo IM, Muscara MN, Maciel FM, Cossermelli W: Nitric oxide synthase inhibitor influences prostaglandin and interleukin-1 production in experimental arthritic joints. Inflamm Res. 1997;46:72-77.
14. Moilanen E, Vuorinen P, Kankaanranta H, Metsa-Ketela T, Vapaatalo H: Inhibition by nitric oxidedonors of human polymorphonuclear leucocyte functions. Br J Pharmacol. 1993;109:852-858.
15. Herndon DN, Trabe LD, Linares H, Flynn JD, Niehaus G, Kramer G, Trabe DL. Etiology of the pulmonary pathophysiology associated with inhalation injury. Resuscitation. 1986;14:43-59.
16. Baxter CR Shires T: Physiological response to crystalloid resuscitation of severe burns. Ann N Y Acad Sci. 1968;150:874-894.
17. Tzao C, Nickerson PA, Russell JA, Noble BK, Steinhorn RH: Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study. Histochem Cell Biol. 2003;119:125-130.
18. Parker TA, Le Cras TD, Kinsella JP, Abman SH: Developmental changes in endothelial nitric oxide synthase expression and activity in ovine fetal lung. Am J Physiol Lung Cell Mol Physiol. 2000;278:L202-L208.
19. Sherman TS, Chen Z, Yuhanna IS, Lau KS, Margraf LR, Shaul PW: Nitric oxide synthase isoform expression in the developing lung epithelium. Am J Physiol. 1999;276:L383-L390.
20. Molinuevo MS, Etcheverry SB, Cortizo AM: Macrophage activation by a vanadyl-aspirin complex is dependent on L-type calcium channel and the generation of nitric oxide. Toxicology. 2005;210:205-212.
21. Choi HS, Rai PR, Chu HW, Cool C, Chan ED: Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am J Respir Crit Care Med 2002;166:178-186.
22. Zhan X, Li D, Johns RA: Immunohistochemical evidence for the NO cGMP signaling pathway in respiratory ciliated epithelia of rat. J Histochem Cytochem. 1999;47:1369-1374.
23. Zhan X, Li D, Johns RA: Expression of endothelial nitric oxide synthase in ciliated epithelia of rats. J Histochem Cytochem. 2003;51:81-87.
24. Shaul PW, North AJ, Wu LC, Wells LB, Brannon TS, Lau KS, Michel T, Margraf LR, Star RA: Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium. J Clin Invest. 1994;94:2231-2236.
25. Bodegas ME, Villaro AC, Montuenga LM, Moncada S, Riveros-Moreno V, Sesma P: Neuronal nitric oxide synthase immunoreactivity in the respiratory tract of the frog, Rana temporaria. Histochem. J. 1995;27:812-818.
26. Guembe L, Villaro AC: Histochemical demonstration of neuronal nitric oxide synthase during development of mouse respiratory tract. Am J Respir Cell Mol Biol. 1999;20:342-351.
27. Stothert JC Jr, Ashley KD, Kramer GC, Herndon DN, Traber LD, Deubel-Ashley K, Traber DL: Intrapulmonary distribution of bronchial blood flow after moderate smoke inhalation. J Appl Physiol. 1990;69:1734-1739.
28. Sakurai H, Johnigan R, Kikuchi Y, Harada M, Traber LD, Traber DL: Effect of reduced bronchial circulation on lung fluid flux after smoke inhalation in sheep. J Appl Physiol. 1998;84:980-986.
29. Efimova O, Volokhov AB, Iliaifar S, Hales CA: Ligation of the bronchial artery in sheep attenuates early pulmonary changes following exposure to smoke. J Appl Physiol. 2000;88:888-893.
30. Soejima K, Traber LD, Schmalstieg FC, Hawkins H, Jodoin JM, Szabo C, Szabo E, Varig L, Salzman A, Traber DL: Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury. Am J Respir Crit Care Med. 2001;163:745-752.
31. Soejima K, McGuire N, Snyder N, Uchida T C, Szabó A, Salzman A, Traber LD, Traber DL: The effect of inducible nitric oxide synthase (iNOS) inhibition on smoke inhalation injury. Shock. 2000;13:261-266.
32. Mizutani A., Enkhbaatar P, Esechie A, Traber LD, Cox RA, Hawkins HK, Deyo DJ, Murakami K, Takayuki N, TraberDL: Pulmonary changes in a mouse model of combined burn and smoke inhalation-induced injury. Appl Physiol. 2008;105:678-684.
33. Enkhbaatar P, Murakami K, Shimoda K, Mizutani A, McGuire R, Schmalstieg F, Cox R, Hawkins H, Jodoin J., Lee S, Traber DL, Herndon DN, Traber LD: Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model. Am J Physiol Regul Integr Comp Physiol. 2003;285:R366-R372.
34. Pietak SP, Delahaye DJ: Airway obstruction following smoke inhalation. Can Med Assoc J. 1976;115:329-331.
35. Cox CS Jr, Zwischenberger JB, Traber DL, Traber LD, Haque AK, Herndon DN: Heparin improves oxygenation and minimizes barotrauma after severe smoke inhalation in an ovine model. Surg Gynecol Obstet. 1993;176:339-349.
36. Sasaki T, Shimura S, Sasaki H, Takishima T: Effect of epithelium on mucus secretion from feline tracheal submucosal glands. J Appl Physiol. 1989;66:764-770.
37. Hubbard GB, Langlinais PC, Shimazu T, Okerberg CV, Mason AD, Pruitt BA: The morphology of smoke inhalation injury in sheep. J Trauma. 1991;31:1477-1486.
38. Cox RA, Burke AS, Soejima K, Murakami K, Katahira J., Traber LD, Herndon DN, Schmalstieg FC, Trabe, DL, Hawkins HK: Airway obstruction in sheep with burn and smoke inhalation injuries. Am J Respir Cell Mol Biol. 2003;29:295-302.
39. Nagaki M, Shimura MN, Irokawa T, Sasaki T, Shirato K: Nitric oxide regulation of glycoconjugate secretion from feline and human airways in vitro. Respir Physiol. 1995;102:89-95.
40. Cox RA, Soejima K, Katahira J., Murakami K, Burke AS, Traber LD, Zwischenberger JB, Schmalstieg FC, Traber DL, Hawkins HK: Inhibition of inducible nitric oxide synthase decreases airway obstruction in sheep following smoke inhalation injury. Presented at the Twenty-Forth Annual Conference on Shock, Marco Island, FL, 2001. Abstract 225.
41. Dwyer TM, Farley JM: Human neutrophil elastase releases two pools of mucinlike glycoconjugate from tracheal submucosal gland cells. Am J Physiol Lung Cell Mol Physiol. 2000;278:L675-L682.
42. Tsicopoulos A, Janin A, Akoum H, Lamblin C, Vorng H, Hamid Q, Tonnel AB,Wallaert B: Cytokine profile in minor salivary glands from patients with bronchial asthma. J Allergy Clin Immunol. 2000;106:687-696.
43. Cox RA, Burke AS, Oliveras G, Zwishenberger JB, Jeschke MG, Schmalstieg FC, Herndon DN, Traber D, Hawkins HK: Acute bronchial obstruction in sheep: histopathology and gland cytokine expression. Exp Lung Res. 2005;31:819-837.
44. Cox RA, Burke AS, Traber DL, Herndon DN, Hawkins HK: Production of pro-inflammatory polypeptides by airway mucous glands and its potential significance. Pulm Pharmacol Ther. 2007;20:172-177.
45. Cox RA, Soejima K, Burke AS, Traber LD, Herndon DN, Schmalstieg FC, Traber DL, Hawkins HK: Enhanced pulmonary expression of endothelin-1 in an ovine model of smoke inhalation injury. J Burn Care Rehabil. 2001;22:375-383.