STAT3-mediated IL-17 production by postseptic T cells exacerbates viral immunopathology of the lung

Shock

Volumn 38, Issue 5, 2012, Pages 515-523

  Mukherjee, Sumanta ^a   Allen, Ronald M ^a   Lukacs, Nicholas W ^a   Kunkel, Steven L ^a   Carson, William F ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

cytokines; infection; Inflammation; lymphocytes; mucus

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; MUCIN 5AC; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; FEMALE; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY INFILTRATE; LIGATION; MOUSE; MUCUS SECRETION; NONHUMAN; PROTEIN BINDING; PUNCTURE; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT INFECTION; SECONDARY INFECTION; SEPSIS; SHAM PROCEDURE; SPLEEN CELL; T LYMPHOCYTE; TH17 CELL; TH2 CELL; VIRAL CLEARANCE; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; INTERFERON-GAMMA; INTERLEUKIN-17; LUNG; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; SEPSIS; STAT3 TRANSCRIPTION FACTOR; TH2 CELLS;

EID: 84868205058     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31826f862c     Document Type: Article

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