Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination

Breast Cancer Research and Treatment

Volumn 136, Issue 2, 2012, Pages 443-455

  Panno, M L ^a   Giordano, F ^a   Rizza, P ^a   Pellegrino, M ^a   Zito, D ^a   Giordano, C ^b   Mauro, L ^a   Catalano, S ^a   Aquila, S ^a   Sisci, D ^a   De Amicis, F ^a   Vivacqua, A ^a   Fuqua, S W A ^a   Ando, S ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Bergapten; Breast cancer cells; ER ubiquitination; SMAD4

Indexed keywords

BERGAPTEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; LUCIFERASE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG STRUCTURE; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MITOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MCF-7 CELLS; METHOXSALEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; TAMOXIFEN; UBIQUITINATION;

EID: 84868198697     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2282-3     Document Type: Article

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