Ethanol Preference in Drosophila melanogaster is Driven by Its Caloric Value

Alcoholism: Clinical and Experimental Research

Volumn 36, Issue 11, 2012, Pages 1903-1912

  Pohl, Jascha B ^a   Baldwin, Brett A ^a   Dinh, Boingoc L ^a   Rahman, Pinkey ^a   Smerek, Dustin ^a   Prado, Francisco J ^a   Sherazee, Nyssa ^a   Atkinson, Nigel S ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Calorie; Drosophila; Nutrition; Preference

Indexed keywords

ALCOHOL; CARBOHYDRATE; GLUCOSE; MALTODEXTRIN; MANNOSE; RIBOSE;

ANIMAL EXPERIMENT; ARTICLE; CALORIE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; FOOD INTAKE; FOOD PREFERENCE; MOTIVATION; NONHUMAN; NUTRITIONAL VALUE; PRIORITY JOURNAL;

ALCOHOL DRINKING; ANIMALS; CHOICE BEHAVIOR; DROSOPHILA MELANOGASTER; ENERGY INTAKE; ETHANOL; FEMALE; FOOD PREFERENCES;

ANIMALIA; DROSOPHILA MELANOGASTER; MAMMALIA;

EID: 84868194448     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2012.01817.x     Document Type: Article

References (43)

1. Atkinson NS (2009) Tolerance in Drosophila. J Neurogenet 23:293-302.
2. Bainton RJ, Tsai LT, Singh CM, Moore MS, Neckameyer WS, Heberlein U (2000) Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila. Curr Biol 10:187-194.
3. Berger KH, Heberlein U, Moore MS (2004) Rapid and chronic: two distinct forms of ethanol tolerance in Drosophila. Alcohol Clin Exp Res 28:1469-1480.
4. Blednov YA, Walker D, Harris RA (2004) Blockade of the leptin-sensitive pathway markedly reduces alcohol consumption in mice. Alcohol Clin Exp Res 28:1683-1692.
5. Burke CJ, Waddell S (2011) Remembering nutrient quality of sugar in Drosophila. Curr Biol 21:746-750.
6. Cadieu N, Cadieu J, El Ghadraoui L, Grimal A, Lamboeuf Y (1999) Conditioning to ethanol in the fruit fly-a study using an inhibitor of ADH. J Insect Physiol 45:579-586.
7. Capy P, Gibert P (2004) Drosophila melanogaster, Drosophila simulans: so similar yet so different. Genetica 120:5-16.
8. Corl AB, Berger KH, Ophir-Shohat G, Gesch J, Simms JA, Bartlett SE, Heberlein U (2009) Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. Cell 137:949-960.
9. Cowmeadow RB, Krishnan HR, Atkinson NS (2005) The slowpoke gene underlies rapid ethanol tolerance in Drosophila. Alcohol Clin Exp Res 29:1777-1786.
10. Dahanukar A, Lei YT, Kwon JY, Carlson JR (2007) Two Gr genes underlie sugar reception in Drosophila. Neuron 56:503-516.
11. Depiereux E, Hougouto N, Lechien J, Libion-Mannaert M, Liétaert MC, Feytmans E, Elens A (1985) Larval behavioral response to environmental ethanol in relation to alcohol dehydrogenase activity level in Drosophila melanogaster. Behav Genet 15:181-188.
12. Devineni AV, Heberlein U (2009) Preferential ethanol consumption in Drosophila models features of addiction. Curr Biol 19:2126-2132.
13. Dus M, Min S, Keene AC, Lee GY, Suh GS (2011) Taste-independent detection of the caloric content of sugar in Drosophila. Proc Natl Acad Sci USA 108:11644-11649.
14. Dzitoyeva S, Dimitrijevic N, Manev H (2003) gamma-Aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence. Proc Natl Acad Sci USA 100:5485-5490.
15. FAO (1998) Carbohydrates in human nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food and Nutrition Paper, No. 66.
16. Folk DG, Bradley TJ (2004) The evolution of recovery from desiccation stress in laboratory-selected populations of Drosophila melanogaster. J Exp Biol 207:2671-2678.
17. Forsander OA (1998) Dietary influences on alcohol intake: a review. J Stud Alcohol 59:26-31.
18. Fujita M, Tanimura T (2011) Drosophila evaluates and learns the nutritional value of sugars. Curr Biol 21:751-755.
19. Gelfand LJ, McDonald JF (1980) Relationship between ADH activity and behavioral response to environmental alcohol in Drosophila. Behav Genet 10:237-249.
20. Gibson JB, May YW, Wilks AV (1981) Genetic variation at the alcohol dehydrogenase locus in Drosophila melanogaster in relation to environmental variation: ethanol levels in breeding sites and allozyme frequencies. Oecologia 51:191-198.
21. Gill K, Amit Z, Smith BR (1996) Alcohol as a food: a commentary on Richter. Physiol Behav 60:1485-1490.
22. Gordesky-Gold B, Rivers N, Ahmed OM, Breslin PA (2008) Drosophila melanogaster prefers compounds perceived sweet by humans. Chem Senses 33:301-309.
23. Ja WW, Carvalho GB, Mak EM, de la Rosa NN, Fang AY, Liong JC, Brummel T, Benzer S (2007) Prandiology of Drosophila and the CAFE assay. Proc Natl Acad Sci USA 104:8253-8256.
24. Libion-Mannaert M, Delcour J, Deltombe-Lietaert MM, Lenelle-Montfort N, Elens A (1976) Ethanol as a "food" for Drosophila melanogaster: influence of the ebony gene. Experientia 32:22-24.
25. Manev H, Dimitrijevic N, Dzitoyeva S (2003) Techniques: fruit flies as models for neuropharmacological research. Trends Pharmacol Sci 24:41-43.
26. Mayfield RD, Harris RA, Schuckit MA (2008) Genetic factors influencing alcohol dependence. Br J Pharmacol 154:275-287.
27. McKenzie JA, McKechnie SW (1979) A comparative study of resource utilization in natural populations of Drosophila melanogaster and D. simulans. Oecologia 40:299-309.
28. McKenzie JA, Parsons PA (1972) Alcohol tolerance: an ecological parameter in the relative success of Drosophila melanogaster and Drosophila simulans. Oecologia 10:373-388.
29. McKenzie JA, Parsons PA (1974) Microdifferentiation in a natural population of Drosophila melanogaster to alcohol in the environment. Genetics 77:385-394.
30. Middleton RJ, Kacser H (1983) Enzyme variation, metabolic flux and fitness: alcohol dehydrogenase in Drosophila melanogaster. Genetics 105:633-650.
31. Moore MS, DeZazzo J, Luk AY, Tully T, Singh CM, Heberlein U (1998) Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell 93:997-1007.
32. Ogueta M, Cibik O, Eltrop R, Schneider A, Scholz H (2010) The influence of Adh function on ethanol preference and tolerance in adult Drosophila melanogaster. Chem Senses 35:813-822.
33. Parsons PA (1980) Larval responses to environmental ethanol in Drosophila melanogaster: variation within and among populations. Behav Genet 10:183-190.
34. Pecsenye K, Lefkovitch LP, Giles BE, Saura A (1994) Does Drosophila-melanogaster use ethanol as an energy-source during starvation. Hereditas 121:225-236.
35. Richter CP (1926) A study of the effect of moderate doses of alcohol on the growth and behavior of the rat. J Exp Zool 44:397-418.
36. Rothenfluh A, Threlkeld RJ, Bainton RJ, Tsai LT, Lasek AW, Heberlein U (2006) Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms. Cell 127:199-211.
37. Scholz H, Ramond J, Singh CM, Heberlein U (2000) Functional ethanol tolerance in Drosophila. Neuron 28:261-271.
38. Shiraiwa T, Carlson JR (2007) Proboscis extension response (PER) assay in Drosophila. J Vis Exp 3:193.
39. Shtonda BB, Avery L (2006) Dietary choice behavior in Caenorhabditis elegans. J Exp Biol 209:89-102.
40. Telonis-Scott M, Hoffmann AA (2003) Isolation of a Drosophila melanogaster desiccation resistant mutant. J Insect Physiol 49:1013-1020.
41. Tompkins L, Cardosa MJ, White FV, Sanders TG (1979) Isolation and analysis of chemosensory behavior mutants in Drosophila melanogaster. Proc Natl Acad Sci USA 76:884-887.
42. Westerfieid WW, Lawrow J (1953) The effect of caloric restriction and thiamine deficiency on the voluntary consumption of alcohol by rats. Q J Stud Alcohol 14:378-384.
43. van der Zwaluw CS, Engels RC (2009) Gene-environment interactions and alcohol use and dependence: current status and future challenges. Addiction 104:907-914.