Recombinant human MFG-E8 attenuates cerebral ischemic injury: Its role in anti-inflammation and anti-apoptosis

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 890-900

  Cheyuo, Cletus ^a,b,c   Jacob, Asha ^a,c   Wu, Rongqian ^a,c   Zhou, Mian ^a,c   Qi, Lei ^a,c   Dong, Weifeng ^a,c   Ji, Youxin ^a,c   Chaung, Wayne W ^a,c   Wang, Haichao ^a,b   Nicastro, Jeffrey ^c   Coppa, Gene F ^c   Wang, Ping ^a,b,c  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b Elmezzi Graduate School of Molecular Medicine   (United States)

^c NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Apoptosis; Cerebral ischemia; Inflammation; MFG E8; Neuroprotection

Indexed keywords

CASPASE; INTERLEUKIN 6; LACTADHERIN; NEUROPROTECTIVE AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BAX; PROTEIN BCL 2; RECOMBINANT LACTADHERIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTI APOPTOSIS ACTIVITY; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ATTENUATION; BLOOD PRESSURE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG SCREENING; HEMODYNAMICS; HISTOPATHOLOGY; HUMAN; INFLAMMATION; LEUKOCYTE ADHERENCE; MALE; MICROGLIA; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN FUNCTION; RAT; SCORING SYSTEM; SURVIVAL; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; ANTIGENS, SURFACE; APOPTOSIS; BLOOD PRESSURE; BRAIN; BRAIN ISCHEMIA; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; MICROGLIA; MILK PROTEINS; NECROSIS; NEUROPROTECTIVE AGENTS; NEUTROPHILS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION;

EID: 84855939217     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.09.018     Document Type: Article

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