Modulation of host cell death pathways by Yersinia species and the type III effector YopK

Advances in Experimental Medicine and Biology

Volumn 954, Issue , 2012, Pages 229-236

  Peters, Kristen N ^a,b   Anderson, Deborah M ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CYSTEINE PROTEINASE; OUTER MEMBRANE PROTEIN; YOPE PROTEIN, YERSINIA; YOPP PROTEIN, YERSINIA; YOPT PROTEIN, YERSINIA;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL CULTURE; FEMALE; MOUSE; PATHOGENICITY; PHYSIOLOGY; YERSINIA;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; FEMALE; MICE; MICE, INBRED BALB C; YERSINIA;

EID: 84868160275     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-3561-7_29     Document Type: Conference Paper

References (43)

1. Aili M, Hallberg B, Wolf-Watz H et al (2002) GAP activity of Yersinia YopE. Methods Enzymol 358:359-370
2. Aili M, Isaksson EL, Carlsson SE et al (2008) Regulation of Yersinia Yop-effector delivery by translocated YopE. Int J Med Microbiol 298:183-192. doi: S1438-4221(07)00086-0 [pii] 10.1016/j. ijmm.2007.04.007
3. Aktories K (2011) Bacterial protein toxins that modify host regulatory GTPases. Nat Rev Microbiol 9:487-498. doi: 10.1038/nrmicro2592 nrmicro2592 [pii]
4. Bergsbaken T, Cookson BT (2007) Macrophage activation redirects Yersinia -infected host cell death from apoptosis to caspase-1-dependent pyroptosis. PLoS Pathog 3:e161. doi: 07-PLPA-RA-0189 [pii] 10.1371/journal.ppat.0030161
5. Bergsbaken T, Cookson BT (2009) Innate immune response during Yersinia infection: critical modulation of cell death mechanisms through phagocyte activation. J Leukoc Biol 86:1153-1158. doi: jlb.0309146 [pii] 10.1189/jlb.0309146
6. Bliska JB (2000) Yop effectors of Yersinia spp. and actin rearrangements. Trends Microbiol 8:205-208. doi: S0966-842X(00)01738-8 [pii]
7. Brodsky IE, Medzhitov R (2008) Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence. PLoS Pathog 4:e1000067. doi: 10.1371/journal.ppat.1000067
8. Brodsky IE, Palm NW, Sadanand S et al (2010) A Yersinia effector protein promotes virulence by preventing in fl ammasome recognition of the type III secretion system. Cell Host Microbe 7:376-387. doi: S1931-3128(10)00139-3 [pii] 10.1016/j. chom.2010.04.009
9. Cornelis GR (2000) Molecular and cell biology aspects of plague. Proc Natl Acad Sci U S A 97:8778-8783. doi: 97/16/8778 [pii]
10. Dewoody R, Merritt PM, Houppert AS et al (2011) YopK regulates the Yersinia pestis type III secretion system from within host cells. Mol Microbiol 79:1445-1461. doi: 10.1111/j.1365-2958.2011.07534.x\
11. Duprez L, Wirawan E, Vanden Berghe T et al (2009) Major cell death pathways at a glance. Microbes Infect 11:1050-1062. doi: S1286-4579(09)00204-4 [pii] 10.1016/j.micinf.2009.08.013
12. Dziarski R (2006) Deadly plague versus mild-mannered TLR4. Nat Immunol 7:1017-1019. doi: ni1006-1017 [pii] 10.1038/ni1006-1017
13. Fink SL, Cookson BT (2007) Pyroptosis and host cell death responses during Salmonella infection. Cell Microbiol 9:2562-2570. doi: CMI1036 [pii]
14. .1111/j.1462-5822.2007.01036.x Franchi L, Eigenbrod T, Munoz-Planillo R et al (2009) The in fl ammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 10:241-247. doi: ni.1703 [pii] 10.1038/ni.1703
15. Garcia JT, Ferracci F, Jackson MW et al (2006) Measurement of effector protein injection by type III and type IV secretion systems by using a 13-residue phosphorylatable glycogen synthase kinase tag. Infect Immun 74:5645-5657. doi: 74/10/5645 [pii] 10.1128/IAI.00690-06
16. Grobner S, Schulz S, Soldanova I et al (2007) Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells. Infect Immun 75:512-517. doi: IAI.00756-06 [pii] 10.1128/IAI.00756-06
17. Holmstrom A, Rosqvist R, Wolf-Watz H et al (1995) YopK, a novel virulence determinant of Yersinia pseudotuberculosis. Contrib Microbiol Immunol 13:239-243
18. Holmstrom A, Petterson J, Rosqvist R et al (1997) YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane. Mol Microbiol 24:73-91
19. Khare S, Luc N, Dorfleutner A, Stehlik C (2010) In fl ammasomes and their activation. Crit Rev Immunol 30:463-487. doi: 76236f9f086f9f9f,533412001b624d 4b [pii]
20. Lamkan fi M, Dixit VM (2011) Modulation of in fl ammasome pathways by bacterial and viral pathogens. J Immunol 187:597-602. doi: 187/2/597 [pii] 10.4049/jimmunol.1100229
21. Lemaitre N, Sebbane F, Long D, Hinnebusch BJ (2006) Yersinia pestis YopJ suppresses tumor necrosis factor alpha induction and contributes to apoptosis of immune cells in the lymph node but is not required for virulence in a rat model of bubonic plague. Infect Immun 74:5126-5131. doi: 74/9/5126 [pii] 10.1128/IAI.00219-06
22. Lilo S, Zheng Y, Bliska JB (2008) Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ. Infect Immun 76:3911-3923. doi: IAI.01695-07 [pii] 10.1128/IAI.01695-07
23. Lukaszewski RA, Kenny DJ, Taylor R et al (2005) Pathogenesis of Yersinia pestis infection in BALB/c mice: effects on host macrophages and neutrophils. Infect Immun 73:7142-7150. doi: 73/11/7142 [pii] 10.1128/IAI.73.11.7142-7150. 2005
24. Mak TW, Yeh WC (2002) Signaling for survival and apoptosis in the immune system. Arthritis Res 4(Suppl 3):S243-S252
25. Marketon MM, DePaolo RW, DeBord KL et al (2005) Plague bacteria target immune cells during infection. Science 309:1739-1741. doi: 1114580 [pii] 10.1126/science.1114580
26. McIntire CR, Yeretssian G, Saleh M (2009) In fl ammasomes in infection and in fl ammation. Apoptosis 14:522-535. doi: 10.1007/s10495-009-0312-3
27. Mejia E, Bliska JB, Viboud GI (2008) Yersinia controls type III effector delivery into host cells by modulating Rho activity. PLoS Pathog 4:e3. doi: 07-PLPARA-0173 [pii] 10.1371/journal.ppat.0040003
28. Monack DM, Mecsas J, Ghori N, Falkow S (1997) Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Proc Natl Acad Sci U S A 94:10385-10390
29. Palmer LE, Hobbie S, Galan JE, Bliska JB (1998) YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol Microbiol 27:953-965
30. Reed LJ, Muench H (1938) A simple method of estimating fi fty percent endpoints. Am J Hyg 27:493-497
31. Santic M, Pavokovic G, Jones S et al (2010) Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis. Microbes Infect 12:126-134. doi: S1286-4579(09)00242-1 [pii] 10.1016/j. micinf.2009.11.003
32. Schotte P, Denecker G, Van Den Broeke A et al (2004) Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta. J Biol Chem 279:25134-25142. doi: 10.1074/jbc.M401245200 M401245200 [pii]
33. Schroder K, Tschopp J (2010) The in fl ammasomes. Cell 140:821-832. doi: S0092-8674(10)00075-9 [pii]
34. Serrels B, Sandilands E, Frame MC (2011) Signaling of the direction-sensing FAK/RACK1/PDE4D5 complex to the small GTPase Rap1. Small Gtpases 2:54-61. doi: 10.4161/sgtp. 2.1.15137 2154-1248-2-1-11 [pii]
35. Thorslund SE, Edgren T, Pettersson J et al (2011) The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function. PLoS One 6:e16784. doi: 10.1371/journal. pone.0016784
36. Viboud GI, Bliska JB (2001) A bacterial type III secretion system inhibits actin polymerization to prevent pore formation in host cell membranes. EMBO J 20:5373-5382. doi: 10.1093/emboj/20.19.5373
37. Viboud GI, Mejia E, Bliska JB (2006) Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection. Cell Microbiol 8:1504-1515. doi: CMI729 [pii] 10.1111/j.1462-5822.2006.00729.x\
38. Witzenrath M, Pache F, Lorenz D et al (2011) The NLRP3 in fl ammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. J Immunol 187:434-440. doi: jimmunol. 1003143 [pii] 10.4049/jimmunol.1003143
39. Wolke S, Ackermann N, Heesemann J (2011) The Yersinia enterocolitica type 3 secretion system (T3SS) as toolbox for studying the cell biological effects of bacterial Rho GTPase modulating T3SS effector proteins. Cell Microbiol. doi: 10.1111/j.1462-5822.2011.01623.x\
40. Wong KW, Isberg RR (2005) Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1. PLoS Pathog 1:e16. doi: 10.1371/journal. ppat.0010016
41. Zauberman A, Cohen S, Mamroud E et al (2006) Interaction of Yersinia pestis with macrophages: limitations in YopJ-dependent apoptosis. Infect Immun 74:3239-3250. doi: 74/6/3239 [pii] 10.1128/IAI.00097-06
42. Zheng Y, Lilo S, Brodsky IE et al (2011) A Yersinia effector with enhanced inhibitory activity on the NF-kappaB pathway activates the NLRP3/ASC/caspase-1 in fl ammasome in macrophages. PLoS Pathog 7:e1002026. doi: 10.1371/journal.ppat.1002026
43. Zumbihl R, Aepfelbacher M, Andor A et al (1999) The cytotoxin YopT of Yersinia enterocolitica induces modi fi cation and cellular redistribution of the small GTP-binding protein RhoA. J Biol Chem 274: 29289-29293