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Volumn 32, Issue 44, 2012, Pages 15271-15276

Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN [1-40]; AMYLOID BETA PROTEIN [1-42]; BETA TUBULIN; SYNAPTOJANIN; SYNAPTOJANIN 1; UNCLASSIFIED DRUG;

EID: 84868145167     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2034-12.2012     Document Type: Article
Times cited : (56)

References (43)
  • 1
    • 34248659126 scopus 로고    scopus 로고
    • Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice
    • CrossRef Medline
    • Alamed J, Wilcock DM, Diamond DM, Gordon MN, Morgan D (2006) Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice. Nat Protoc 1:1671-1679. CrossRef Medline
    • (2006) Nat Protoc , vol.1 , pp. 1671-1679
    • Alamed, J.1    Wilcock, D.M.2    Diamond, D.M.3    Gordon, M.N.4    Morgan, D.5
  • 2
    • 84855798135 scopus 로고    scopus 로고
    • Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction
    • CrossRef Medline
    • Alldred MJ, Duff KE, Ginsberg SD (2012) Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction. Neurobiol Dis 45:751-762. CrossRef Medline
    • (2012) Neurobiol Dis , vol.45 , pp. 751-762
    • Alldred, M.J.1    Duff, K.E.2    Ginsberg, S.D.3
  • 3
    • 11144294809 scopus 로고    scopus 로고
    • Impaired Pavlovian cued fear conditioning in Tg2576 mice expressing a human mutant amyloid precursor protein gene
    • CrossRef Medline
    • Barnes P, Good M (2005) Impaired Pavlovian cued fear conditioning in Tg2576 mice expressing a human mutant amyloid precursor protein gene. Behav Brain Res 157:107-117. CrossRef Medline
    • (2005) Behav Brain Res , vol.157 , pp. 107-117
    • Barnes, P.1    Good, M.2
  • 4
    • 84857642949 scopus 로고    scopus 로고
    • The toxic A oligomer and Alzheimer's disease: An emperor in need of clothes
    • CrossRef Medline
    • Benilova I, Karran E, De Strooper B (2012) The toxic A oligomer and Alzheimer's disease: an emperor in need of clothes. Nat Neurosci 15:349-357. CrossRef Medline
    • (2012) Nat Neurosci , vol.15 , pp. 349-357
    • Benilova, I.1    Karran, E.2    De Strooper, B.3
  • 6
    • 84859584667 scopus 로고    scopus 로고
    • The genetics of Alzheimer's disease
    • CrossRef Medline
    • Bertram L, Tanzi RE (2012) The genetics of Alzheimer's disease. Prog Mol Biol Transl Sci 107:79-100. CrossRef Medline
    • (2012) Prog Mol Biol Transl Sci , vol.107 , pp. 79-100
    • Bertram, L.1    Tanzi, R.E.2
  • 7
    • 84863462907 scopus 로고    scopus 로고
    • Structural plasticity of dendritic spines
    • CrossRef Medline
    • Bosch M, Hayashi Y (2012) Structural plasticity of dendritic spines. Curr Opin Neurobiol 22:383-388. CrossRef Medline
    • (2012) Curr Opin Neurobiol , vol.22 , pp. 383-388
    • Bosch, M.1    Hayashi, Y.2
  • 8
    • 34249696007 scopus 로고    scopus 로고
    • Rapid, concurrent alterations in pre-and postsynaptic structure induced by naturally-secreted amyloid-beta protein
    • CrossRef Medline
    • Calabrese B, Shaked GM, Tabarean IV, Braga J, Koo EH, Halpain S (2007) Rapid, concurrent alterations in pre-and postsynaptic structure induced by naturally-secreted amyloid-beta protein. Mol Cell Neurosci 35:183-193. CrossRef Medline
    • (2007) Mol Cell Neurosci , vol.35 , pp. 183-193
    • Calabrese, B.1    Shaked, G.M.2    Tabarean, I.V.3    Braga, J.4    Koo, E.H.5    Halpain, S.6
  • 10
    • 77951060396 scopus 로고    scopus 로고
    • PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila
    • CrossRef Medline
    • Chiang HC, Wang L, Xie Z, Yau A, Zhong Y (2010) PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila. Proc Natl Acad Sci U S A 107:7060-7065. CrossRef Medline
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7060-7065
    • Chiang, H.C.1    Wang, L.2    Xie, Z.3    Yau, A.4    Zhong, Y.5
  • 13
    • 33749836234 scopus 로고    scopus 로고
    • Phosphoinositides in cell regulation and membrane dynamics
    • CrossRef Medline
    • Di Paolo G, De Camilli P (2006) Phosphoinositides in cell regulation and membrane dynamics. Nature 443:651-657. CrossRef Medline
    • (2006) Nature , vol.443 , pp. 651-657
    • Di Paolo, G.1    De Camilli, P.2
  • 14
    • 79955051063 scopus 로고    scopus 로고
    • Linking lipids to Alzheimer's disease: Cholesterol and beyond
    • CrossRef Medline
    • Di Paolo G, Kim TW (2011) Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat Rev Neurosci 12:284-296. CrossRef Medline
    • (2011) Nat Rev Neurosci , vol.12 , pp. 284-296
    • Di Paolo, G.1    Kim, T.W.2
  • 15
    • 34249733132 scopus 로고    scopus 로고
    • Increase of locomotor activity underlying the behavioral disinhibition in tg2576 mice
    • CrossRef Medline
    • Gil-Bea FJ, Aisa B, Schliebs R, Ramírez MJ (2007) Increase of locomotor activity underlying the behavioral disinhibition in tg2576 mice. Behav Neurosci 121:340-344. CrossRef Medline
    • (2007) Behav Neurosci , vol.121 , pp. 340-344
    • Gil-Bea, F.J.1    Aisa, B.2    Schliebs, R.3    Ramírez, M.J.4
  • 16
    • 56249139742 scopus 로고    scopus 로고
    • Regulation of postsynaptic AMPA responses by synaptojanin 1
    • CrossRef Medline
    • Gong LW, De Camilli P (2008) Regulation of postsynaptic AMPA responses by synaptojanin 1. Proc Natl Acad Sci U S A 105:17561-17566. CrossRef Medline
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 17561-17566
    • Gong, L.W.1    De Camilli, P.2
  • 17
    • 0031434562 scopus 로고    scopus 로고
    • Synaptojanin 1: Localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15
    • CrossRef Medline
    • Haffner C, Takei K, Chen H, Ringstad N, Hudson A, Butler MH, Salcini AE, Di Fiore PP, De Camilli P (1997) Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15. FEBS Lett 419:175-180. CrossRef Medline
    • (1997) FEBS Lett , vol.419 , pp. 175-180
    • Haffner, C.1    Takei, K.2    Chen, H.3    Ringstad, N.4    Hudson, A.5    Butler, M.H.6    Salcini, A.E.7    Di Fiore, P.P.8    De Camilli, P.9
  • 19
    • 77249153190 scopus 로고    scopus 로고
    • Loss of 7 nicotinic receptors enhances-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease
    • CrossRef Medline
    • Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT (2010) Loss of 7 nicotinic receptors enhances-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. J Neurosci 30:2442-2453. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 2442-2453
    • Hernandez, C.M.1    Kayed, R.2    Zheng, H.3    Sweatt, J.D.4    Dineley, K.T.5
  • 20
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • CrossRef Medline
    • Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102. CrossRef Medline
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6    Yang, F.7    Cole, G.8
  • 21
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • CrossRef Medline
    • Huang Y, Mucke L (2012) Alzheimer mechanisms and therapeutic strategies. Cell 148:1204-1222. CrossRef Medline
    • (2012) Cell , vol.148 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 22
    • 33644560354 scopus 로고    scopus 로고
    • Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation
    • CrossRef Medline
    • Kopec CD, Li B, Wei W, Boehm J, Malinow R (2006) Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci 26:2000-2009. CrossRef Medline
    • (2006) J Neurosci , vol.26 , pp. 2000-2009
    • Kopec, C.D.1    Li, B.2    Wei, W.3    Boehm, J.4    Malinow, R.5
  • 23
    • 33846633336 scopus 로고    scopus 로고
    • A oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
    • CrossRef Medline
    • Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL (2007) A oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 27:796-807. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 796-807
    • Lacor, P.N.1    Buniel, M.C.2    Furlow, P.W.3    Clemente, A.S.4    Velasco, P.T.5    Wood, M.6    Viola, K.L.7    Klein, W.L.8
  • 25
    • 0345743706 scopus 로고    scopus 로고
    • Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses
    • CrossRef Medline
    • Lee SY, Wenk MR, Kim Y, Nairn AC, De Camilli P (2004) Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proc Natl Acad Sci U S A 101:546-551. CrossRef Medline
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 546-551
    • Lee, S.Y.1    Wenk, M.R.2    Kim, Y.3    Nairn, A.C.4    de Camilli, P.5
  • 26
    • 73149103505 scopus 로고    scopus 로고
    • Phosphatidylinositol (4,5)-bisphosphate regulation of N-methyl-D-aspartate receptor channels in cortical neurons
    • CrossRef Medline
    • Mandal M, Yan Z (2009) Phosphatidylinositol (4,5)-bisphosphate regulation of N-methyl-D-aspartate receptor channels in cortical neurons. Mol Pharmacol 76:1349-1359. CrossRef Medline
    • (2009) Mol Pharmacol , vol.76 , pp. 1349-1359
    • Mandal, M.1    Yan, Z.2
  • 27
    • 53949083619 scopus 로고    scopus 로고
    • Pavlovian fear conditioning as a behavioral assay for hippocampus and amygdala function: Cautions and caveats
    • CrossRef Medline
    • Maren S (2008) Pavlovian fear conditioning as a behavioral assay for hippocampus and amygdala function: cautions and caveats. Eur J Neurosci 28:1661-1666. CrossRef Medline
    • (2008) Eur J Neurosci , vol.28 , pp. 1661-1666
    • Maren, S.1
  • 28
    • 59849125052 scopus 로고    scopus 로고
    • Mutations in phosphoinositide metabolizing enzymes and human disease
    • CrossRef Medline
    • McCrea HJ, De Camilli P (2009) Mutations in phosphoinositide metabolizing enzymes and human disease. Physiology (Bethesda) 24:8-16. CrossRef Medline
    • (2009) Physiology (Bethesda) , vol.24 , pp. 8-16
    • McCrea, H.J.1    de Camilli, P.2
  • 29
    • 34249050764 scopus 로고    scopus 로고
    • Phosphatidylinositol-4,5-bisphosphate regulates NMDA receptor activity through-actinin
    • CrossRef Medline
    • Michailidis IE, Helton TD, Petrou VI, Mirshahi T, Ehlers MD, Logothetis DE (2007) Phosphatidylinositol-4,5-bisphosphate regulates NMDA receptor activity through-actinin. J Neurosci 27:5523-5532. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 5523-5532
    • Michailidis, I.E.1    Helton, T.D.2    Petrou, V.I.3    Mirshahi, T.4    Ehlers, M.D.5    Logothetis, D.E.6
  • 30
    • 38949175007 scopus 로고    scopus 로고
    • A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging
    • CrossRef Medline
    • Miller JA, Oldham MC, Geschwind DH (2008) A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci 28:1410-1420. CrossRef Medline
    • (2008) J Neurosci , vol.28 , pp. 1410-1420
    • Miller, J.A.1    Oldham, M.C.2    Geschwind, D.H.3
  • 32
    • 50349083510 scopus 로고    scopus 로고
    • Phosphoinositides suppress gamma-secretase in both the detergent-soluble and-insoluble states
    • CrossRef Medline
    • Osawa S, Funamoto S, Nobuhara M, Wada-Kakuda S, Shimojo M, Yagishita S, Ihara Y (2008) Phosphoinositides suppress gamma-secretase in both the detergent-soluble and-insoluble states. J Biol Chem 283:19283-19292. CrossRef Medline
    • (2008) J Biol Chem , vol.283 , pp. 19283-19292
    • Osawa, S.1    Funamoto, S.2    Nobuhara, M.3    Wada-Kakuda, S.4    Shimojo, M.5    Yagishita, S.6    Ihara, Y.7
  • 33
    • 53049089639 scopus 로고    scopus 로고
    • Direct and potent regulation of gamma-secretase by its lipid microenvironment
    • CrossRef Medline
    • Osenkowski P, Ye W, Wang R, Wolfe MS, Selkoe DJ (2008) Direct and potent regulation of gamma-secretase by its lipid microenvironment. J Biol Chem 283:22529-22540. CrossRef Medline
    • (2008) J Biol Chem , vol.283 , pp. 22529-22540
    • Osenkowski, P.1    Ye, W.2    Wang, R.3    Wolfe, M.S.4    Selkoe, D.J.5
  • 34
    • 0032708232 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein
    • CrossRef Medline
    • Petanceska SS, Gandy S (1999) The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein. J Neurochem 73:2316-2320. CrossRef Medline
    • (1999) J Neurochem , vol.73 , pp. 2316-2320
    • Petanceska, S.S.1    Gandy, S.2
  • 35
    • 84884285081 scopus 로고    scopus 로고
    • Synaptic changes in Alzheimer's disease and its models
    • Advance online publication. Retrieved September 15, 2012. doi:10.1016/j.neuroscience.2012.05.050. CrossRef Medline
    • Pozueta J, Lefort R, Shelanski ML (2012) Synaptic changes in Alzheimer's disease and its models. Neuroscience. Advance online publication. Retrieved September 15, 2012. doi:10.1016/j.neuroscience.2012.05.050. CrossRef Medline
    • (2012) Neuroscience
    • Pozueta, J.1    Lefort, R.2    Shelanski, M.L.3
  • 36
    • 44349154735 scopus 로고    scopus 로고
    • Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images
    • CrossRef Medline
    • Rodriguez A, Ehlenberger DB, Dickstein DL, Hof PR, Wearne SL (2008) Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PLoS One 3:e1997. CrossRef Medline
    • (2008) PLoS One , vol.3
    • Rodriguez, A.1    Ehlenberger, D.B.2    Dickstein, D.L.3    Hof, P.R.4    Wearne, S.L.5
  • 37
    • 77953279191 scopus 로고    scopus 로고
    • Phospholipase A2 and arachidonic acid in Alzheimer's disease
    • CrossRef Medline
    • Sanchez-Mejia RO, Mucke L (2010) Phospholipase A2 and arachidonic acid in Alzheimer's disease. Biochim Biophys Acta 1801:784-790. CrossRef Medline
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 784-790
    • Sanchez-Mejia, R.O.1    Mucke, L.2
  • 38
    • 22844438739 scopus 로고    scopus 로고
    • Tissue processing prior to protein analysis and amyloid-beta quantitation
    • Medline
    • Schmidt SD, Jiang Y, Nixon RA, Mathews PM (2005) Tissue processing prior to protein analysis and amyloid-beta quantitation. Methods Mol Biol 299:267-278. Medline
    • (2005) Methods Mol Biol , vol.299 , pp. 267-278
    • Schmidt, S.D.1    Jiang, Y.2    Nixon, R.A.3    Mathews, P.M.4
  • 39
    • 33947314641 scopus 로고    scopus 로고
    • Natural oligomers of the Alzheimer amyloidprotein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
    • CrossRef Medline
    • Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL (2007) Natural oligomers of the Alzheimer amyloidprotein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci 27:2866-2875. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 2866-2875
    • Shankar, G.M.1    Bloodgood, B.L.2    Townsend, M.3    Walsh, D.M.4    Selkoe, D.J.5    Sabatini, B.L.6
  • 40
    • 70349755717 scopus 로고    scopus 로고
    • Reversal of long-term dendritic spine alterations in Alzheimer disease models
    • CrossRef Medline
    • Smith DL, Pozueta J, Gong B, Arancio O, Shelanski M (2009) Reversal of long-term dendritic spine alterations in Alzheimer disease models. Proc Natl Acad Sci U S A 106:16877-16882. CrossRef Medline
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16877-16882
    • Smith, D.L.1    Pozueta, J.2    Gong, B.3    Arancio, O.4    Shelanski, M.5
  • 43
    • 0022978912 scopus 로고
    • Characteristics of a Ca2 / calmodulin-dependent binding of the Ca2 channel antagonist, nitrendipine, to a postsynaptic density fraction isolated from canine cerebral cortex
    • Medline
    • Wu K, Sachs L, Carlin RK, Siekevitz P (1986) Characteristics of a Ca2 / calmodulin-dependent binding of the Ca2 channel antagonist, nitrendipine, to a postsynaptic density fraction isolated from canine cerebral cortex. Brain Res 387:167-184. Medline
    • (1986) Brain Res , vol.387 , pp. 167-184
    • Wu, K.1    Sachs, L.2    Carlin, R.K.3    Siekevitz, P.4


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