Elastin signaling in wound repair

Birth Defects Research Part C - Embryo Today: Reviews

Volumn 96, Issue 3, 2012, Pages 248-257

  Almine, Jessica F ^a   Wise, Steven G ^a,b   Weiss, Anthony S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b HEART RESEARCH INSTITUTE   (Australia)

Author keywords

Cell signaling; Elastin; Fetal; Wound healing

Indexed keywords

BINDING PROTEIN; ELASTIN; ELASTIN BINDING PROTEIN; FIBRIN; GLYCOSAMINOGLYCAN; INTEGRIN; MATRIX METALLOPROTEINASE; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVITY; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; DERMIS; ELASTIC FIBER; ENZYME ACTIVITY; ENZYME SYNTHESIS; EPIDERMIS; EXTRACELLULAR MATRIX; FETUS DEVELOPMENT; HUMAN; INFLAMMATION; KERATINOCYTE; LANGERHANS CELL; MELANOCYTE; MERKEL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SCAR FORMATION; SIGNAL TRANSDUCTION; SKIN BLOOD FLOW; SKIN BLOOD VESSEL; SKIN FIBROBLAST; SKIN FUNCTION; WOUND HEALING;

ADULT; AGE FACTORS; CICATRIX; ELASTIN; FETUS; HUMANS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; SKIN PHYSIOLOGICAL PHENOMENA; WOUND HEALING;

EID: 84868138471     PISSN: 1542975X     EISSN: 15429768     Source Type: Journal    
DOI: 10.1002/bdrc.21016     Document Type: Article

References (92)

1. Akhtar K, Broekelmann TJ, Song H, Turk J, et al. 2011. Oxidative modifications of the C-terminal domain of tropoelastin prevent cell binding. J Biol Chem 286: 13574-13582.
2. Almine JF, Bax DV, Mithieux SM, et al. 2010. Elastin-based materials. Chem Soc Rev 39: 3371-3379.
3. Amadeu TP, Braune AS, Porto LC, et al. 2004. Fibrillin-1 and elastin are differentially expressed in hypertrophic scars and keloids. Wound Repair Regen 12: 169-174.
4. Antonicelli F, Bellon G, Debelle L, et al. 2007. Elastin-elastases and inflamm-aging. Curr Top Dev Biol 79: 99-155.
5. Armstrong JR, Ferguson MW. 1995. Ontogeny of the skin and the transition from scar-free to scarring phenotype during wound healing in the pouch young of a marsupial, Monodelphis domestica. Dev Biol 169: 242-260.
6. Barczyk M, Carracedo S, Gullberg D. 2010. Integrins. Cell Tissue Res 339: 269-280.
7. Bax DV, Rodgers UR, Bilek MM, et al. 2009. Cell adhesion to tropoelastin is mediated via the C-terminal GRKRK motif and integrin alphaVbeta3. J Biol Chem 284: 28616-28623.
8. Borradori L, Sonnenberg A. 1999. Structure and function of hemidesmosomes: more than simple adhesion complexes. J Invest Dermatol 112: 411-418.
9. Brassart B, Fuchs P, Huet E, et al. 2001. Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts. J Biol Chem 276: 5222-5227.
10. Broekelmann TJ, Kozel BA, Ishibashi H, et al. 2005. Tropoelastin interacts with cell-surface glycosaminoglycans via its COOH-terminal domain. J Biol Chem 280: 40939-40947.
11. Brouard M, Barrandon Y. 2003. Controlling skin morphogenesis: hope and despair. Curr Opin Biotechnol 14: 520-525.
12. Broughton G II, Janis JE, Attinger CE. 2006. Wound healing: an overview. Plast Reconstr Surg 117( 7 Suppl): 1e-S-32e-S.
13. Buchanan EP, Longaker MT, Lorenz HP. 2009. Fetal skin wound healing. Adv Clin Chem 48: 137-161.
14. Cantarelli B, Duca L, Blanchevoye C, et al. 2009. Elastin peptides antagonize ceramide-induced apoptosis. FEBS Lett 583: 2385-2391.
15. Chen WY, Abatangelo G. 1999. Functions of hyaluronan in wound repair. Wound Repair Regen 7: 79-89.
16. Colwell AS, Beanes SR, Soo C, et al. 2005. Increased angiogenesis and expression of vascular endothelial growth factor during scarless repair. Plast Reconstr Surg 115: 204-212.
17. Colwell AS, Longaker MT, Peter Lorenz H. 2008. Identification of differentially regulated genes in fetal wounds during regenerative repair. Wound Repair Regen 16: 450-459.
18. Coolen NA, Schouten KC, Middelkoop E, et al. 2010. Comparison between human fetal and adult skin. Arch Dermatol Res 302: 47-55.
19. Cowin AJ, Brosnan MP, Holmes TM, et al. 1998. Endogenous inflammatory response to dermal wound healing in the fetal and adult mouse. Dev Dyn 212: 385-393.
20. Daamen WF, Veerkamp JH, van Hest JC, et al. 2007. Elastin as a biomaterial for tissue engineering. Biomaterials 28: 4378-4398.
21. Dang CM, Beanes SR, Lee H, et al. 2003. Scarless fetal wounds are associated with an increased matrix metalloproteinase-to-tissue-derived inhibitor of metalloproteinase ratio. Plast Reconstr Surg 111: 2273-2285.
22. de Vries HJ, Middelkoop E, Mekkes JR, et al. 1994. Dermal regeneration in native non-cross-linked collagen sponges with different extracellular matrix molecules. Wound Repair Regen 2: 37-47.
23. Duca L, Blanchevoye C, Cantarelli B, et al. 2007. The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J Biol Chem 282: 12484-12491.
24. Duca L, Floquet N, Alix AJ, et al. 2004. Elastin as a matrikine. Crit Rev Oncol Hematol 49: 235-244.
25. Egozi EI, Ferreira AM, Burns AL, et al. 2003. Mast cells modulate the inflammatory but not the proliferative response in healing wounds. Wound Repair Regen 11: 46-54.
26. El Ghalbzouri A, Lamme E, Ponec M. 2002. Crucial role of fibroblasts in regulating epidermal morphogenesis. Cell Tissue Res 310: 189-199.
27. El Ghalbzouri A, Ponec M. 2004. Diffusible factors released by fibroblasts support epidermal morphogenesis and deposition of basement membrane components. Wound Repair Regen 12: 359-367.
28. Epstein EHJr, Munderloh NH. 1978. Human skin collagen. Presence of type I and type III at all levels of the dermis. J Biol Chem 253: 1336-1337.
29. Faury G, Usson Y, Robert-Nicoud M, et al. 1998. Nuclear and cytoplasmic free calcium level changes induced by elastin peptides in human endothelial cells. Proc Natl Acad Sci USA 95: 2967-2972.
30. Ferguson MW, O'Kane S. 2004. Scar-free healing: from embryonic mechanisms to adult therapeutic intervention. Philos Trans R Soc Lond B Biol Sci 359: 839-850.
31. Flavell SJ, Hou TZ, Lax S, et al. 2008. Fibroblasts as novel therapeutic targets in chronic inflammation. Br J Pharmacol 153( Suppl 1): S241-S246.
32. Fleischmajer R, Utani A, MacDonald ED, et al. 1998. Initiation of skin basement membrane formation at the epidermo-dermal interface involves assembly of laminins through binding to cell membrane receptors. J Cell Sci 111: 1929-1940.
33. Fujimoto N, Tajima S, Ishibashi A. 2000. Elastin peptides induce migration and terminal differentiation of cultured keratinocytes via 67 kDa elastin receptor in vitro: 67 kDa elastin receptor is expressed in the keratinocytes eliminating elastic materials in elastosis perforans serpiginosa. J Invest Dermatol 115: 633-639.
34. Fyrand O. 1979. Studies on fibronectin in the skin. I. Indirect immunofluorescence studies in normal human skin. Br J Dermatol 101: 263-270.
35. Garrod DR. 1993. Desmosomes and hemidesmosomes. Curr Opin Cell Biol 5: 30-40.
36. Gay S, Martin GR, Muller PK, et al. 1976. Simultaneous synthesis of types I and III collagen by fibroblasts in culture. Proc Natl Acad Sci USA 73: 4037-4040.
37. Grinnell F. 1982. Fibronectin and wound healing. Am J Dermatopathol 4: 185-188.
38. Gurtner GC, Werner S, Barrandon Y, et al. 2008. Wound repair and regeneration. Nature 453: 314-321.
39. Hashimoto T, Suzuki Y, Tanihara M, et al. 2004. Development of alginate wound dressings linked with hybrid peptides derived from laminin and elastin. Biomaterials 25: 1407-1414.
40. Hinek A, Rabinovitch M, Keeley F, et al. 1993. The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase. J Clin Invest 91: 1198-1205.
41. Hinek A, Wang Y, Liu K, et al. 2005. Proteolytic digest derived from bovine ligamentum nuchae stimulates deposition of new elastin-enriched matrix in cultures and transplants of human dermal fibroblasts. J Dermatol Sci 39: 155-166.
42. Hinek A, Wrenn DS, Mecham RP, et al. 1988. The elastin receptor: a galactoside-binding protein. Science 239: 1539-1541.
43. Hynes RO. 1987. Integrins: a family of cell surface receptors. Cell 48: 549-554.
44. Hynes RO. 2002. Integrins: bidirectional, allosteric signaling machines. Cell 110: 673-687.
45. Kajiya H, Tanaka N, Inazumi T, et al. 1997. Cultured human keratinocytes express tropoelastin. J Invest Dermatol 109: 641-644.
46. Kamoun A, Landeau JM, Godeau G, et al. 1995. Growth stimulation of human skin fibroblasts by elastin-derived peptides. Cell Adhes Commun 3: 273-281.
47. Kielty CM, Sherratt MJ, Shuttleworth CA. 2002. Elastic fibers. J Cell Sci 115: 2817-2828.
48. Krafts KP. 2010. Tissue repair: the hidden drama. Organogenesis 6: 225-233.
49. Laing P. 1998. The development and complications of diabetic foot ulcers. Am J Surg 176( 2A Suppl): 11S-19S.
50. Larson BJ, Longaker MT, Lorenz HP. 2010. Scarless fetal wound healing: a basic science review. Plast Reconstr Surg 126: 1172-1180.
51. Lee DY, Cho KH. 2005. The effects of epidermal keratinocytes and dermal fibroblasts on the formation of cutaneous basement membrane in three-dimensional culture systems. Arch Dermatol Res 296: 296-302.
52. Levenson SM, Geever EF, Crowley LV, et al. 1965. The healing of rat skin wounds. Ann Surg 161: 293-308.
53. Longaker MT, Whitby DJ, Ferguson MW, et al. 1994. Adult skin wounds in the fetal environment heal with scar formation. Ann Surg 219: 65-72.
54. Lovvorn HNIII, Cheung DT, Nimni ME, et al. 1999. Relative distribution and crosslinking of collagen distinguish fetal from adult sheep wound repair. J Pediatr Surg 34: 218-223.
55. Marinkovich MP, Keene DR, Rimberg CS, et al. 1993. Cellular origin of the dermal-epidermal basement membrane. Dev Dyn 197: 255-267.
56. Masunaga T. 2006. Epidermal basement membrane: its molecular organization and blistering disorders. Connect Tissue Res 47: 55-66.
57. McMillan JR, Akiyama M, Shimizu H. 2003. Epidermal basement membrane zone components: ultrastructural distribution and molecular interactions. J Dermatol Sci 31: 169-177.
58. Mecham RP, Hinek A, Entwistle R, et al. 1989. Elastin binds to a multifunctional 67-kilodalton peripheral membrane protein. Biochemistry 28: 3716-3722.
59. Mecham RP, Lange G, Madaras J, et al. 1981. Elastin synthesis by ligamentum nuchae fibroblasts: effects of culture conditions and extracellular matrix on elastin production. J Cell Biol 90: 332-338.
60. Metcalfe AD, Ferguson MW. 2007. Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration. J R Soc Interface 4: 413-437.
61. Mithieux SM, Weiss AS. 2005. Elastin. Adv Protein Chem 70: 437-461.
62. Mochizuki S, Brassart B, Hinek A. 2002. Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells. J Biol Chem 277: 44854-44863.
63. Moon SE, Bhagavathula N, Varani J. 2002. Keratinocyte stimulation of matrix metalloproteinase-1 production and proliferation in fibroblasts: regulation through mitogen-activated protein kinase signalling events. Br J Cancer 87: 457-464.
64. Pasquali-Ronchetti I, Baccarani-Contri M. 1997. Elastic fiber during development and aging. Microsc Res Tech 38: 428-435.
65. Petersen E, Wagberg F, Angquist KA. 2002. Serum concentrations of elastin-derived peptides in patients with specific manifestations of atherosclerotic disease. Eur J Vasc Endovasc Surg 24: 440-444.
66. Pieraggi MT, Bouissou H, Angelier C, et al. 1985. [The fibroblast]. Ann Pathol 5: 65-76.
67. Pierce RA, Moore CH, Arikan MC. 2006. Positive transcriptional regulatory element located within exon 1 of elastin gene. Am J Physiol Lung Cell Mol Physiol 291: L391-L399.
68. Raghunath M, Bachi T, Meuli M, et al. 1996. Fibrillin and elastin expression in skin regenerating from cultured keratinocyte autografts: morphogenesis of microfibrils begins at the dermo-epidermal junction and precedes elastic fiber formation. J Invest Dermatol 106: 1090-1095.
69. Ramelet AA, Hirt-Burri N, Raffoul W, et al. 2009. Chronic wound healing by fetal cell therapy may be explained by differential gene profiling observed in fetal versus old skin cells. Exp Gerontol 44: 208-218.
70. Robinet A, Fahem A, Cauchard JH, et al. 2005. Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP. J Cell Sci 118: 343-356.
71. Rodgers UR, Weiss AS. 2004. Integrin alpha v beta 3 binds a unique non-RGD site near the C-terminus of human tropoelastin. Biochimie 86: 173-178.
72. Rodgers UR, Weiss AS. 2005. Cellular interactions with elastin. Pathol Biol (Paris) 53: 390-398.
73. Rusciani A, Duca L, Sartelet H, et al. 2010. Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. PLoS One 5: e14010.
74. Sawicki G, Marcoux Y, Sarkhosh K, et al. 2005. Interaction of keratinocytes and fibroblasts modulates the expression of matrix metalloproteinases-2 and -9 and their inhibitors. Mol Cell Biochem 269: 209-216.
75. Seeley RR, Stephens TD, Tate P. 2005. Essentials of anatomy and physiology. 5 ed. New York: McGraw-Hill.
76. Senior RM, Griffin GL, Mecham RP. 1982. Chemotactic responses of fibroblasts to tropoelastin and elastin-derived peptides. J Clin Invest 70: 614-618.
77. Senior RM, Griffin GL, Mecham RP, et al. 1984. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J Cell Biol 99: 870-874.
78. Sephel GC, Buckley A, Davidson JM. 1987. Developmental initiation of elastin gene expression by human fetal skin fibroblasts. J Invest Dermatol 88: 732-735.
79. Shah M, Foreman DM, Ferguson MW. 1995. Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J Cell Sci 108: 985-1002.
80. Singer AJ, Clark RA. 1999. Cutaneous wound healing. N Engl J Med 341: 738-746.
81. Smith RS, Smith TJ, Blieden TM, et al. 1997. Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am J Pathol 151: 317-322.
82. Smola H, Thiekotter G, Fusenig NE. 1993. Mutual induction of growth factor gene expression by epidermal-dermal cell interaction. J Cell Biol 122: 417-429.
83. Sorrell JM, Caplan AI. 2009. Fibroblasts-a diverse population at the center of it all. Int Rev Cell Mol Biol 276: 161-214.
84. Swee MH, Parks WC, Pierce RA. 1995. Developmental regulation of elastin production. Expression of tropoelastin pre-mRNA persists after down-regulation of steady-state mRNA levels. J Biol Chem 270: 14899-14906.
85. Tajima S, Wachi H, Uemura Y, et al. 1997. Modulation by elastin peptide VGVAPG of cell proliferation and elastin expression in human skin fibroblasts. Arch Dermatol Res 289: 489-492.
86. Toriseva M, Kahari VM. 2009. Proteinases in cutaneous wound healing. Cell Mol Life Sci 66: 203-224.
87. Trott A. 1988. Mechanisms of surface soft tissue trauma. Ann Emerg Med 17: 1279-1283.
88. Vrhovski B, Weiss AS. 1998. Biochemistry of tropoelastin. Eur J Biochem 258: 1-18.
89. Werner S, Krieg T, Smola H. 2007. Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol 127: 998-1008.
90. Wise SG, Weiss AS. 2009. Tropoelastin. Int J Biochem Cell Biol 41: 494-497.
91. Yeo GC, Keeley FW, Weiss AS. 2011. Coacervation of tropoelastin. Adv Colloid Interface Sci 167: 94-103.
92. Zhang MC, He L, Giro M, et al. 1999. Cutis laxa arising from frameshift mutations in exon 30 of the elastin gene (ELN). J Biol Chem 274: 981-986.