메뉴 건너뛰기




Volumn 43, Issue 5, 2012, Pages 2027-2035

EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation

Author keywords

Breast cancer; EBP50; EGFR; ERK1 2; PDZ; Phosphorylation; Protein interaction

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; EZRIN RADIXIN MOESIN BINDING PHOSPHOPROTEIN 50; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84868137932     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-012-1277-z     Document Type: Article
Times cited : (37)

References (41)
  • 1
    • 79954554297 scopus 로고    scopus 로고
    • Predictive molecular markers of response to epidermal growth factor receptor(EGFR) family-targeted therapies
    • Barton S, Starling N, Swanton C (2010) Predictive molecular markers of response to epidermal growth factor receptor(EGFR) family-targeted therapies. Curr Cancer Drug Targets 10(8):799-812
    • (2010) Curr Cancer Drug Targets , vol.10 , Issue.8 , pp. 799-812
    • Barton, S.1    Starling, N.2    Swanton, C.3
  • 2
    • 0031842973 scopus 로고    scopus 로고
    • Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc
    • Chen W, Martindale JL, Holbrook NJ, Liu Y (1998) Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. Mol Cell Biol 18(9):5178-5188 (Pubitemid 28388101)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.9 , pp. 5178-5188
    • Chen, W.1    Martindale, J.L.2    Holbrook, N.J.3    Liu, Y.4
  • 3
    • 73949098416 scopus 로고    scopus 로고
    • The PDZ domain protein CAL interacts with mGluR5a and modulates receptor expression
    • Cheng S, Zhang J, Zhu P, Ma Y, Xiong Y, Sun L, Xu J, Zhang H, He J (2010) The PDZ domain protein CAL interacts with mGluR5a and modulates receptor expression. J Neurochem 112(3):588-598
    • (2010) J Neurochem , vol.112 , Issue.3 , pp. 588-598
    • Cheng, S.1    Zhang, J.2    Zhu, P.3    Ma, Y.4    Xiong, Y.5    Sun, L.6    Xu, J.7    Zhang, H.8    He, J.9
  • 4
    • 75049083197 scopus 로고    scopus 로고
    • Investigating the function of three non-synonymous SNPs in EGFR gene: Structural modelling and association with breast cancer
    • Choura M, Frikha F, Kharrat N, Aifa S, Rebai A (2010) Investigating the function of three non-synonymous SNPs in EGFR gene: structural modelling and association with breast cancer. Protein J 29(1):50-54
    • (2010) Protein J , vol.29 , Issue.1 , pp. 50-54
    • Choura, M.1    Frikha, F.2    Kharrat, N.3    Aifa, S.4    Rebai, A.5
  • 5
    • 0036404954 scopus 로고    scopus 로고
    • +exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1
    • DOI 10.1016/S0006-291X(02)02428-2, PII S0006291X02024282
    • Chun J, Kwon T, Lee E, Suh PG, Choi EJ, Sun Kang S (2002) The Na(?)/H(?) exchanger regulatory factor 2 mediates phosphor-ylation of serum-and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1. Biochem Bio-phys Res Commun 298(2):207-215 (Pubitemid 35286329)
    • (2002) Biochemical and Biophysical Research Communications , vol.298 , Issue.2 , pp. 207-215
    • Chun, J.1    Kwon, T.2    Lee, E.3    Suh, P.-G.4    Choi, E.-J.5    Sun Kang, S.6
  • 9
    • 0037166275 scopus 로고    scopus 로고
    • Elastase-released epidermal growth factor recruits epidermal growth factor receptor and extracellular signal-regulated kinases to down-regulate tropoelastin mRNA in lung fibroblasts
    • DOI 10.1074/jbc.M200243200
    • DiCamillo SJ, Carreras I, Panchenko MV, Stone PJ, Nugent MA, Foster JA, Panchenko MP (2002) Elastase-released epidermal growth factor recruits epidermal growth factor receptor and extracellular signal-regulated kinases to down-regulate tropoe-lastin mRNA in lung fibroblasts. J Biol Chem 277(21):18938-18946 (Pubitemid 34952455)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.21 , pp. 18938-18946
    • Dicamillo, S.J.1    Carreras, I.2    Panchenko, M.V.3    Stone, P.J.4    Nugent, M.A.5    Foster, J.A.6    Panchenko, M.P.7
  • 14
    • 36849063719 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of ErbB4 is enhanced by PSD95 and repressed by protein tyrosine phosphatase receptor type Z
    • DOI 10.1093/jb/mvm140
    • Fujikawa A, Chow JP, Shimizu H, Fukada M, Suzuki R, Noda M (2007) Tyrosine phosphorylation of ErbB4 is enhanced by PSD95 and repressed by protein tyrosine phosphatase receptor type Z. J Biochem 142(3):343-350 (Pubitemid 350221837)
    • (2007) Journal of Biochemistry , vol.142 , Issue.3 , pp. 343-350
    • Fujikawa, A.1    Chow, J.P.H.2    Shimizu, H.3    Fukada, M.4    Suzuki, R.5    Noda, M.6
  • 16
  • 17
    • 84863067986 scopus 로고    scopus 로고
    • Novel EGFR-TK inhibitor EKB-569 inhibits hepatocellular carcinoma cell proliferation by AKT and MAPK pathways
    • Kim H, Lim HY (2011) Novel EGFR-TK inhibitor EKB-569 inhibits hepatocellular carcinoma cell proliferation by AKT and MAPK pathways. J Korean Med Sci 26(12):1563-1568
    • (2011) J Korean Med Sci , vol.26 , Issue.12 , pp. 1563-1568
    • Kim, H.1    Lim, H.Y.2
  • 18
    • 0037462743 scopus 로고    scopus 로고
    • ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activation
    • DOI 10.1074/jbc.M205819200
    • Kim SW, Hayashi M, Lo JF, Yang Y, Yoo JS, Lee JD (2003) ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activation. J Biol Chem 278(4):2661-2668 (Pubitemid 36801346)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.4 , pp. 2661-2668
    • Kim, S.-W.1    Hayashi, M.2    Lo, J.-F.3    Yang, Y.4    Yoo, J.-S.5    Lee, J.-D.6
  • 19
    • 0033992633 scopus 로고    scopus 로고
    • Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors
    • Klapper LN, Kirschbaum MH, Sela M, Yarden Y (2000) Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. Adv Cancer Res 77:25-79 (Pubitemid 29439302)
    • (2000) Advances in Cancer Research , vol.77 , pp. 25-79
    • Klapper, L.N.1    Kirschbaum, M.H.2    Sela, M.3    Yarden, Y.4
  • 23
  • 24
    • 80255132722 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex
    • doi:10.1002/jso.21999
    • Lim YC, Cha YY (2011) Epigallocatechin-3-gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex. J Surg Oncol doi. doi:10.1002/jso.21999
    • (2011) J Surg Oncol Doi
    • Lim, Y.C.1    Cha, Y.Y.2
  • 25
    • 1542346154 scopus 로고    scopus 로고
    • Wnt signalling via the epidermal growth factor receptor: A role in breast cancer
    • DOI 10.1186/bcr737
    • Musgrove EA (2004) Wnt signalling via the epidermal growth factor receptor: a role in breast cancer? Breast Cancer Res 6(2):65-68 (Pubitemid 38324844)
    • (2004) Breast Cancer Research , vol.6 , Issue.2 , pp. 65-68
    • Musgrove, E.A.1
  • 26
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA, Hynes NE (2000) The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 19(13):3159-3167 (Pubitemid 30428195)
    • (2000) EMBO Journal , vol.19 , Issue.13 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 27
    • 79952664476 scopus 로고    scopus 로고
    • EGFR is involved in control of gastric cell proliferation through activation of MAPK and Src signalling pathways in early-weaned rats
    • Osaki LH, Figueiredo PM, Alvares EP, Gama P (2011) EGFR is involved in control of gastric cell proliferation through activation of MAPK and Src signalling pathways in early-weaned rats. Cell Prolif 44(2):174-182
    • (2011) Cell Prolif , vol.44 , Issue.2 , pp. 174-182
    • Osaki, L.H.1    Figueiredo, P.M.2    Alvares, E.P.3    Gama, P.4
  • 29
    • 44849096490 scopus 로고    scopus 로고
    • + exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells
    • + exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells. Breast Cancer Res 10(1):R5
    • (2008) Breast Cancer Res , vol.10 , Issue.1
    • Pan, Y.1    Weinman, E.J.2    Dai, J.L.3
  • 30
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, Normanno N (1995) Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19(3):183-232
    • (1995) Crit Rev Oncol Hematol , vol.19 , Issue.3 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 31
    • 0038121958 scopus 로고    scopus 로고
    • EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma
    • DOI 10.1053/jhep.2003.50270
    • Shibata T, Chuma M, Kokubu A, Sakamoto M, Hirohashi S (2003) EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma. Hepatology 38(1):178-186 (Pubitemid 36775809)
    • (2003) Hepatology , vol.38 , Issue.1 , pp. 178-186
    • Shibata, T.1    Chuma, M.2    Kokubu, A.3    Sakamoto, M.4    Hirohashi, S.5
  • 32
    • 35548992253 scopus 로고    scopus 로고
    • Pharmacological characterization of MP-412 (AV-412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor
    • DOI 10.1111/j.1349-7006.2007.00613.x
    • Suzuki T, Fujii A, Ohya J, Amano Y, Kitano Y, Abe D, Nakamura H (2007) Pharmacological characterization of MP-412 (AV-412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor. Cancer Sci 98(12):1977-1984 (Pubitemid 350002206)
    • (2007) Cancer Science , vol.98 , Issue.12 , pp. 1977-1984
    • Suzuki, T.1    Fujii, A.2    Ohya, J.3    Amano, Y.4    Kitano, Y.5    Abe, D.6    Nakamura, H.7
  • 33
    • 33644504867 scopus 로고    scopus 로고
    • PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
    • DOI 10.1038/sj.emboj.7600979, PII 7600979
    • Takahashi Y, Morales FC, Kreimann EL, Georgescu M-M (2006) PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling. EMBO J 25(4):910-920 (Pubitemid 43292451)
    • (2006) EMBO Journal , vol.25 , Issue.4 , pp. 910-920
    • Takahashi, Y.1    Morales, F.C.2    Kreimann, E.L.3    Georgescu, M.-M.4
  • 34
    • 0037313817 scopus 로고    scopus 로고
    • Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis
    • DOI 10.1038/ng1072
    • Takeuchi A, Mishina Y, Miyaishi O, Kojima E, Hasegawa T, Isobe K (2003) Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Nat Genet 33(2):172-176 (Pubitemid 36177069)
    • (2003) Nature Genetics , vol.33 , Issue.2 , pp. 172-176
    • Takeuchi, A.1    Mishina, Y.2    Miyaishi, O.3    Kojima, E.4    Hasegawa, T.5    Isobe, K.-I.6
  • 35
    • 34247262095 scopus 로고    scopus 로고
    • NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility
    • DOI 10.1091/mbc.E06-10-0960
    • Theisen CS, Wahl JK 3rd, Johnson KR, Wheelock MJ (2007) NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility. Mol Biol Cell 18(4):1220-1232 (Pubitemid 46626617)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.4 , pp. 1220-1232
    • Theisen, C.S.1    Wahl III, J.K.2    Johnson, K.R.3    Wheelock, M.J.4
  • 36
    • 23844473290 scopus 로고    scopus 로고
    • Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases
    • DOI 10.1074/jbc.M504761200
    • Valiente M, Andres-Pons A, Gomar B, Torres J, Gil A, Tapparel C, Antonarakis SE, Pulido R (2005) Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phos-phorylation by microtubule-associated serine/threonine kinases. J Biol Chem 280(32):28936-28943 (Pubitemid 41161339)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.32 , pp. 28936-28943
    • Valiente, M.1    Andres-Pons, A.2    Gomar, B.3    Torres, J.4    Gil, A.5    Tapparel, C.6    Antonarakis, S.E.7    Pulido, R.8
  • 37
    • 4043110739 scopus 로고    scopus 로고
    • Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors
    • DOI 10.1038/sj.onc.1207802
    • Wang L, Pan Y, Dai JL (2004) Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors. Oncogene 23(35):5978-5985 (Pubitemid 39093542)
    • (2004) Oncogene , vol.23 , Issue.35 , pp. 5978-5985
    • Wang, L.1    Pan, Y.2    Jia, L.D.3
  • 39
    • 33746899628 scopus 로고    scopus 로고
    • Association with HSP90 inhibits Cbl-mediated down-regulation of mutant epidermal growth factor receptors
    • DOI 10.1158/0008-5472.CAN-06-1042
    • Yang S, Qu S, Perez-Tores M, Sawai A, Rosen N, Solit DB, Arteaga CL (2006) Association with HSP90 inhibits Cbl-mediated down-regulation of mutant epidermal growth factor receptors. Cancer Res 66(14):6990-6997 (Pubitemid 44197674)
    • (2006) Cancer Research , vol.66 , Issue.14 , pp. 6990-6997
    • Yang, S.1    Qu, S.2    Perez-Tores, M.3    Sawai, A.4    Rosen, N.5    Solit, D.B.6    Arteaga, C.L.7
  • 40
    • 76449115479 scopus 로고    scopus 로고
    • The beta1-adrenergic receptor mediates extracellular signal-regulated kinase activation via Galphas
    • Zheng J, Shen H, Xiong Y, Yang X, He J (2010a) The beta1-adrenergic receptor mediates extracellular signal-regulated kinase activation via Galphas. Amino Acids 38(1):75-84
    • (2010) Amino Acids , vol.38 , Issue.1 , pp. 75-84
    • Zheng, J.1    Shen, H.2    Xiong, Y.3    Yang, X.4    He, J.5
  • 41
    • 77951665829 scopus 로고    scopus 로고
    • EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity
    • Zheng JF, Sun LC, Liu H, Huang Y, Li Y, He J (2010b) EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity. Amino Acids 38(4):1261-1268
    • (2010) Amino Acids , vol.38 , Issue.4 , pp. 1261-1268
    • Zheng, J.F.1    Sun, L.C.2    Liu, H.3    Huang, Y.4    Li, Y.5    He, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.