A longitudinal study of the long-term consequences of drinking during pregnancy: Heavy in utero alcohol exposure disrupts the normal processes of brain development

Journal of Neuroscience

Volumn 32, Issue 44, 2012, Pages 15243-15251

  Lebel, Catherine ^a   Mattson, Sarah N ^c   Riley, Edward P ^c   Jones, Kenneth L ^d   Adnams, Colleen M ^e   May, Philip A ^f   Bookheimer, Susan Y ^g   O'Connor, Mary J ^g   Narr, Katherine L ^a   Kan, Eric ^b   Abaryan, Zvart ^b   Sowell, Elizabeth R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c SAN DIEGO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CAPE TOWN   (South Africa)

^f University of North Carolina   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; AGE; ALCOHOL CONSUMPTION; ARTICLE; BEHAVIOR; BRAIN DEVELOPMENT; BRAIN MATURATION; BRAIN SIZE; CHILD; COGNITION; CONTROLLED STUDY; FACE ASYMMETRY; FEMALE; GENDER; HUMAN; INTELLIGENCE QUOTIENT; LONGITUDINAL STUDY; MALE; NERVE CELL PLASTICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL CORTEX; PREGNANCY; PRENATAL EXPOSURE; PRESCHOOL CHILD; PRIORITY JOURNAL; RELIABILITY; SCHOOL CHILD;

ADOLESCENT; AGING; ALCOHOL DRINKING; BRAIN; CEREBRAL CORTEX; CHILD; CHILD BEHAVIOR; CHILD, PRESCHOOL; COGNITION; ETHNIC GROUPS; FACIAL ASYMMETRY; FEMALE; FETAL ALCOHOL SYNDROME; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTELLIGENCE TESTS; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; PREGNANCY; PREGNANCY TRIMESTERS; PRENATAL EXPOSURE DELAYED EFFECTS; SEX CHARACTERISTICS;

EID: 84868129087     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1161-12.2012     Document Type: Article

References (42)

1. Adnams CM, Sorour P, Kalberg WO, Kodituwakku P, Perold MD, Kotze A, September S, Castle B, Gossage J, May PA (2007) Language and literacy outcomes from a pilot intervention study for children with fetal alcohol spectrum disorders in South Africa. Alcohol 41:403-414.
2. Archibald SL, Fennema-Notestine C, Gamst A, Riley EP, Mattson SN, Jernigan TL (2001) Brain dysmorphology in individuals with severe prenatal alcohol exposure. Dev Med Child Neurol 43:148-154.
3. Astley SJ, Clarren SK (2000) Diagnosing the full spectrum of fetal alcohol- exposed individuals: introducing the 4-digit diagnostic code. Alcohol Al-cohol 35:400-410.
4. Astley SJ, Aylward EH, Olson HC, Kerns K, Brooks A, Coggins TE, Davies J, Dorn S, Gendler B, Jirikowic T, Kraegel P, Maravilla K, Richards T (2009) Magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders. Alcohol Clin Exp Res 33:1671-1689.
5. Baroncelli L, Braschi C, Spolidoro M, Begenisic T, Sale A, Maffei L (2010) Nurturing brain plasticity: impact of environmental enrichment. Cell Death Differ 17:1092-1103.
6. Chen X, Coles CD, Lynch ME, Hu X (2012) Understanding specific effects of prenatal alcohol exposure on brain structure in young adults. Hum Brain Mapp 33:1663-1676.
7. Fields RD (2011) Imaging learning: the search for a memory trace. Neuroscientist 17:185-196.
8. Giedd JN, Rapoport JL (2010) Structural MRI of pediatric brain development: what have we learned and where are we going? Neuron 67:728-734.
9. Giedd JN, Lenroot RK, Shaw P, Lalonde F, Celano M, White S, Tossell J, Addington A, Gogtay N (2008) Trajectories of anatomic brain development as a phenotype. Novartis Found Symp 289:101-112; discussion 112-118, 193-195.
10. Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaituzis AC, Nugent TF 3rd, Herman DH, Clasen LS, Toga AW, Rapoport JL, Thompson PM (2004) Dynamic mapping of human cortical development during child- hood through early adulthood. Proc Natl Acad Sci U S A 101:8174-8179.
11. Hoyme HE, May PA, Kalberg WO, Kodituwakku P, Gossage JP, Trujillo PM, Buckley DG, Miller JH, Aragon AS, Khaole N, Viljoen DL, Jones KL, Robinson LK (2005) A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria. Pediatrics 115:39-47.
12. Huttenlocher PR (1979) Synaptic density in human frontal cortex- developmental changes and effects of aging. Brain Res 163:195-205.
13. Huttenlocher PR, de Courten C (1987) The development of synapses in striate cortex of man. Hum Neurobiol 6:1-9.
14. Jones KL, Robinson LK, Bakhireva LN, Marintcheva G, Storojev V, Strahova A, Sergeevskaya S, Budantseva S, Mattson SN, Riley EP, Chambers CD (2006) Accuracy of the diagnosis of physical features of fetal alcohol syndrome by pediatricians after specialized training. Pediatrics 118: e1734-e1738.
15. Lebel C, Rasmussen C, Wyper K, Walker L, Andrew G, Yager J, Beaulieu C (2008) Brain diffusion abnormalities in children with fetal alcohol spectrum disorder. Alcohol Clin Exp Res 32:1732-1740.
16. Mattson SN, Foroud T, Sowell ER, Jones KL, Coles CD, Fagerlund A, Autti-Rämö I, May PA, Adnams CM, Konovalova V, Wetherill L, Arenson AD, Barnett WK, Riley EP (2010) Collaborative initiative on fetal alcohol spectrum disorders: methodology of clinical projects. Alcohol 44:635-641.
17. Mattson SN, Crocker N, Nguyen TT (2011) Fetal alcohol spectrum disorders: neuropsychological and behavioral features. Neuropsychol Rev 21: 81-101.
18. May PA, Brooke L, Gossage JP, Croxford J, Adnams C, Jones KL, Robinson L, Viljoen D (2000) Epidemiology of fetal alcohol syndrome in a South African community in the Western Cape Province. Am J Public Health 90:1905-1912.
19. May PA, Gossage JP, Marais AS, Adnams CM, Hoyme HE, Jones KL, Robinson LK, Khaole NC, Snell C, Kalberg WO, Hendricks L, Brooke L, Stellavato C, Viljoen DL (2007) The epidemiology of fetal alcohol syndrome and partial FAS in a South African community. Drug Alcohol Depend 88:259-271.
20. May PA, Gossage JP, Marais AS, Hendricks LS, Snell CL, Tabachnick BG, Stellavato C, Buckley DG, Brooke LE, Viljoen DL (2008) Maternal risk factors for fetal alcohol syndrome and partial fetal alcohol syndrome in South Africa: a third study. Alcohol Clin Exp Res 32:738-753.
21. Nardelli A, Lebel C, Rasmussen C, Andrew G, Beaulieu C (2011) Extensive deep gray matter volume reductions in children and adolescents with fetal alcohol spectrum disorders. Alcohol Clin Exp Res 35:1404-1417.
22. O'Leary-Moore SK, Parnell SE, Lipinski RJ, Sulik KK (2011) Magnetic resonance-based imaging in animal models of fetal alcohol spectrum disorder. Neuropsychol Rev 21:167-185.
23. Ramsden S, Richardson FM, Josse G, Thomas MS, Ellis C, Shakeshaft C, Seghier ML, Price CJ (2011) Verbal and non-verbal intelligence changes in the teenage brain. Nature 479:113-116.
24. Reuter M, Fischl B (2011) Avoiding asymmetry-induced bias in longitudinal image processing. Neuroimage 57:19-21.
25. Reuter M, Rosas HD, Fischl B (2010) Highly accurate inverse consistent registration: a robust approach. Neuroimage 53:1181-1196.
26. Riley EP, Infante MA, Warren KR (2011) Fetal alcohol spectrum disorders: an overview. Neuropsychol Rev 21:73-80.
27. Roussotte FF, Sulik KK, Mattson SN, Riley EP, Jones KL, Adnams CM, May PA, O'Connor MJ, Narr KL, Sowell ER (2012) Regional brain volume reductions relate to facial dysmorphology and neurocognitive function in fetal alcohol spectrum disorders. Hum Brain Mapp 33:920-937.
28. Shaw P, Greenstein D, Lerch J, Clasen L, Lenroot R, Gogtay N, Evans A, Rapoport J, Giedd J (2006) Intellectual ability and cortical development in children and adolescents. Nature 440:676-679.
29. Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D, Clasen L, Evans A, Giedd J, Rapoport JL (2007) Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci U S A 104:19649-19654.
30. Sowell ER, Thompson PM, Holmes CJ, Jernigan TL, Toga AW (1999) In vivo evidence for post-adolescent brain maturation in frontal and striatal regions. Nat Neurosci 2:859-861.
31. Sowell ER, Thompson PM, Mattson SN, Tessner KD, Jernigan TL, Riley EP, Toga AW (2001) Voxel-based morphometric analyses of the brain in children and adolescents prenatally exposed to alcohol. Neuroreport 12:515-523.
32. Sowell ER, Thompson PM, Peterson BS, Mattson SN, Welcome SE, Henkenius AL, Riley EP, Jernigan TL, Toga AW (2002) Mapping cortical gray matter asymmetry patterns in adolescents with heavy prenatal alcohol exposure. Neuroimage 17:1807-1819.
33. Sowell ER, Mattson SN, Kan E, Thompson PM, Riley EP, Toga AW (2008a) Abnormal cortical thickness and brain-behavior correlation patterns in individuals with heavy prenatal alcohol exposure. Cereb Cortex 18:136-144.
34. Sowell ER, Johnson A, Kan E, Lu LH, Van Horn JD, Toga AW, O'Connor MJ, Bookheimer SY (2008b) Mapping white matter integrity and neurobehavioral correlates in children with fetal alcohol spectrum disorders. J Neurosci 28:1313-1319.
35. Sulik KK (2005) Genesis of alcohol-induced craniofacial dysmorphism. Exp Biol Med (Maywood) 230:366-375.
36. Thompson PM, Vidal C, Giedd JN, Gochman P, Blumenthal J, Nicolson R, Toga AW, Rapoport JL (2001) Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia. Proc Natl Acad Sci U S A 98:11650-11655.
37. Vidal CN, Rapoport JL, Hayashi KM, Geaga JA, Sui Y, McLemore LE, Alaghband Y, Giedd JN, Gochman P, Blumenthal J, Gogtay N, Nicolson R, Toga AW, Thompson PM (2006) Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia. Arch Gen Psychiatry 63:25-34.
38. Viljoen DL, Gossage JP, Brooke L, Adnams CM, Jones KL, Robinson LK, Hoyme HE, Snell C, Khaole NC, Kodituwakku P, Asante KO, Findlay R, Quinton B, Marais AS, Kalberg WO, May PA (2005) Fetal alcohol syndrome epidemiology in a South African community: a second study of a very high prevalence area. J Stud Alcohol 66:593-604.
39. Yakovlev PI, Lecours A-R (1967) The myelogenetic cycles of regional maturation of the brain. In: Regional development of the brain early in life (Minkowski A, ed), pp 3-70. Boston: Blackwell Scientific.
40. Yang Y, Roussotte F, Kan E, Sulik KK, Mattson SN, Riley EP, Jones KL, Adnams CM, May PA, O'Connor MJ, Narr KL, Sowell ER (2012a) Abnormal cortical thickness alterations in fetal alcohol spectrum disorders and their relationships with facial dysmorphology. Cereb Cortex 22:1170-1179.
41. Yang Y, Phillips OR, Kan E, Sulik KK, Mattson SN, Riley EP, Jones KL, Adnams CM, May PA, O'Connor MJ, Narr KL, Sowell ER (2012b) Callosal thickness reductions relate to facial dysmorphology in fetal alcohol spectrum disorders. Alcohol Clin Exp Res. 36:798-806.
42. Zhou D, Lebel C, Lepage C, Rasmussen C, Evans A, Wyper K, Pei J, Andrew G, Massey A, Massey D, Beaulieu C (2011) Developmental cortical thinning in fetal alcohol spectrum disorders. Neuroimage 58:16-25.