Dopaminergic differentiation of human pluripotent cells

Current Protocols in Stem Cell Biology

Volumn 1, Issue SUPPL.22, 2012, Pages

  Boyer, Leah F ^a,b   Campbell, Benjamin ^a   Larkin, Samantha ^a   Mu, Yanling ^a   Gage, Fred H ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dopaminergic differentiation; Neural development; Pluripotent stem cells

Indexed keywords

ANIMAL; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CULTURE TECHNIQUE; CYTOLOGY; DOPAMINERGIC NERVE CELL; HUMAN; METHODOLOGY; MOUSE; PLURIPOTENT STEM CELL;

ANIMALS; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; DOPAMINERGIC NEURONS; HUMANS; MICE; PLURIPOTENT STEM CELLS;

EID: 84868124417     PISSN: 19417322     EISSN: 19388969     Source Type: Journal    
DOI: 10.1002/9780470151808.sc01h06s22     Document Type: Article

References (12)

1. Alavian, K, Scholz, C., and Simon, H. 2008. Transcriptional regulation of mesencephalic dopaminergic DA neurons: The full circle of life and death. Movement Disorders 23:319-328.
2. Andersson, E., Tryggvason, U., Deng, Q., Frilling, S.,Alekseenko,A., Robert,B., Perlmann,T., and Ericson, J. 2006. Identification of intrinsic determinants of midbrain dopaminergic neurons. Cell 124:393-405.
3. Chambers, S., Fasano, C., Papapetrou, E., Tomishima, M., Sadelain, M., and Studer, L. 2009. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27:275-280.
4. Hwang, K., Kim, J., Chang, W., Kim, D., Lim, S., Kang, S., Song, B., Ha, H., Huh, Y., Choi, I., Hwang, D., Song, H., Jang, Y., Kim, S., and Kim, D. 2008. Chemicals that modulate stem cell differentiation. Proc. Natl. Acad. Sci. U.S.A. 105:7467-7471.
5. Kawasaki, H., Mizuseki,, Nishikawa, S., Kaneko, S.,Kuwana, Y, Nakanishi, S., Nishikawa, S., and Sasai, Y. 2000. Induction of midbrain dopaminergic neurons from ES cells by stromal cellderived inducing activity. Neuron 28:31-40.
6. Kriks, S., Shim, J., Piao, J., Ganat, Y., Wakeman, D., Xie, Z., Carrillo-Reid, L., Auyeung, G., Anotonacci, C., Buch, A., Yang, L., Beal, M.F., Surmeier, D.J., Kordower, J.H., Tabar, W., and Studer, L. 2011. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480:547-551.
7. Okabe, S., Forsberg-Nilsson, K., Spiro, A., Segal, M., and McKay, R. 1996. Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech. Dev. 59:89-102.
8. Prakash, N. and Wurst, W. 2006. Genetic networks controlling the development of midbrain dopaminergic neurons. J. Physiol. 575:403-410.
9. Roy, S., Cleren, C., Singh, S., Yang, L., Beal, MF., and Goldman, SA. 2006. Functional engraftment of human ES cell derived dopaminergic neurons enriched by coculture with telomerase immortalized midbrain astrocytes. Nat. Med. 12:1259-1268.
10. Sachetti, P., Sousa, K.M., Hall, A.C., Liste, I., Steffensen, K.R., Theofilopoulos, S., Parish, C.L., Hazenburg, C., Richter, L.A., Hovatta, O., Gustafsson, J.A., and Arenas, E. 2009. Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell 5:409-419.
11. Yan, Y., Yang, D., Zarnowska, E.D., Du, Z.,Werbel, B., Valliere, C., Pearce, R.A., Thomson, J.A., and Zhang, S.C. 2005. Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 23:781-790.
12. Yin, M., Liu, S., Yin, Y., Li, S., Li, Z., Wu, X., Zhang, B., Ang, S., Ding, Y., and Zhou, J. 2009. Ventral mesencephalon-enriched genes that regulate the development of dopaminergic neurons in vivo. J. Neurosci. 29:5170-5182.