SIRPα Controls the Activity of the Phagocyte NADPH Oxidase by Restricting the Expression of gp91phox

Cell Reports

Volumn 2, Issue 4, 2012, Pages 748-755

  van Beek, Ellen M ^a   Zarate, Julian Alvarez ^a   van Bruggen, Robin ^a   Schornagel, Karin ^a   Tool, Anton T J ^a   Matozaki, Takashi ^b   Kraal, Georg ^c   Roos, Dirk ^a   van den Berg, Timo K ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD47 ANTIGEN; MEMBRANE RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SIGNAL REGULATOR PROTEIN ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CATALYSIS; CELL ACTIVATION; CELL ISOLATION; CELL MATURATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RESPIRATORY BURST; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD47; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION REGULATION; GRANULOCYTES; HUMANS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MUTATION; MYELOID CELLS; NADPH OXIDASE; PHAGOCYTES; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; RECEPTORS, IMMUNOLOGIC; RESPIRATORY BURST; SIGNAL TRANSDUCTION;

MUS;

EID: 84868122752     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.08.027     Document Type: Article

References (30)

1. Adams S., van der Laan L.J., Vernon-Wilson E., Renardel de Lavalette C., Döpp E.A., Dijkstra C.D., Simmons D.L., van den Berg T.K. Signal-regulatory protein is selectively expressed by myeloid and neuronal cells. J. Immunol. 1998, 161:1853-1859.
2. Alblas J., Honing H., de Lavalette C.R., Brown M.H., Dijkstra C.D., van den Berg T.K. Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways. Mol. Cell. Biol. 2005, 25:7181-7192.
3. Barclay A.N., Brown M.H. The SIRP family of receptors and immune regulation. Nat. Rev. Immunol. 2006, 6:457-464.
4. Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 2007, 87:245-313.
5. de Vries H.E., Hendriks J.J., Honing H., De Lavalette C.R., van der Pol S.M., Hooijberg E., Dijkstra C.D., van den Berg T.K. Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium. J. Immunol. 2002, 168:5832-5839.
6. Dong L.W., Kong X.N., Yan H.X., Yu L.X., Chen L., Yang W., Liu Q., Huang D.D., Wu M.C., Wang H.Y. Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction. Mol. Immunol. 2008, 45:3025-3035.
7. Dong Q., Siminovitch K.A., Fialkow L., Fukushima T., Downey G.P. Negative regulation of myeloid cell proliferation and function by the SH2 domain-containing tyrosine phosphatase-1. J. Immunol. 1999, 162:3220-3230.
8. Fujioka Y., Matozaki T., Noguchi T., Iwamatsu A., Yamao T., Takahashi N., Tsuda M., Takada T., Kasuga M. A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol. Cell. Biol. 1996, 16:6887-6899.
9. Hatherley D., Graham S.C., Turner J., Harlos K., Stuart D.I., Barclay A.N. Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47. Mol. Cell 2008, 31:266-277.
10. Jiang P., Lagenaur C.F., Narayanan V. Integrin-associated protein is a ligand for the P84 neural adhesion molecule. J. Biol. Chem. 1999, 274:559-562.
11. Kautz B., Kakar R., David E., Eklund E.A. SHP1 protein-tyrosine phosphatase inhibits gp91PHOX and p67PHOX expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous Cis elements in the CYBB and NCF2 genes. J. Biol. Chem. 2001, 276:37868-37878.
12. Kong X.N., Yan H.X., Chen L., Dong L.W., Yang W., Liu Q., Yu L.X., Huang D.D., Liu S.Q., Liu H., et al. LPS-induced down-regulation of signal regulatory protein alpha contributes to innate immune activation in macrophages. J. Exp. Med. 2007, 204:2719-2731.
13. Kruger J., Butler J.R., Cherapanov V., Dong Q., Ginzberg H., Govindarajan A., Grinstein S., Siminovitch K.A., Downey G.P. Deficiency of Src homology 2-containing phosphatase 1 results in abnormalities in murine neutrophil function: studies in motheaten mice. J. Immunol. 2000, 165:5847-5859.
14. Kuijpers T.W., van Bruggen R., Kamerbeek N., Tool A.T., Hicsonmez G., Gurgey A., Karow A., Verhoeven A.J., Seeger K., Sanal O., et al. Natural history and early diagnosis of LAD-1/variant syndrome. Blood 2007, 109:3529-3537.
15. Lee W.Y., Weber D.A., Laur O., Severson E.A., McCall I., Jen R.P., Chin A.C., Wu T., Gernert K.M., Parkos C.A. Novel structural determinants on SIRP alpha that mediate binding to CD47. J. Immunol. 2007, 179:7741-7750.
16. Lindsey S., Huang W., Wang H., Horvath E., Zhu C., Eklund E.A. Activation of SHP2 protein-tyrosine phosphatase increases HoxA10-induced repression of the genes encoding gp91(PHOX) and p67(PHOX). J. Biol. Chem. 2007, 282:2237-2249.
17. Liu Y., Bühring H.J., Zen K., Burst S.L., Schnell F.J., Williams I.R., Parkos C.A. Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration. J. Biol. Chem. 2002, 277:10028-10036.
18. Liu Y., Tong Q., Zhou Y., Lee H.W., Yang J.J., Bühring H.J., Chen Y.T., Ha B., Chen C.X., Yang Y., Zen K. Functional elements on SIRPalpha IgV domain mediate cell surface binding to CD47. J. Mol. Biol. 2007, 365:680-693.
19. Nikolic T., de Bruijn M.F., Lutz M.B., Leenen P.J. Developmental stages of myeloid dendritic cells in mouse bone marrow. Int. Immunol. 2003, 15:515-524.
20. Oldenborg P.A., Zheleznyak A., Fang Y.F., Lagenaur C.F., Gresham H.D., Lindberg F.P. Role of CD47 as a marker of self on red blood cells. Science 2000, 288:2051-2054.
21. Reeves E.P., Lu H., Jacobs H.L., Messina C.G., Bolsover S., Gabella G., Potma E.O., Warley A., Roes J., Segal A.W. Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature 2002, 416:291-297.
22. Roos D., van Bruggen R., Meischl C. Oxidative killing of microbes by neutrophils. Microbes Infect. 2003, 5:1307-1315.
23. Seiffert M., Cant C., Chen Z., Rappold I., Brugger W., Kanz L., Brown E.J., Ullrich A., Bühring H.J. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47. Blood 1999, 94:3633-3643.
24. Stacey K.J., Sester D.P., Sweet M.J., Hume D.A. Macrophage activation by immunostimulatory DNA. Curr. Top. Microbiol. Immunol. 2000, 247:41-58.
25. van Beek E.M., Cochrane F., Barclay A.N., van den Berg T.K. Signal regulatory proteins in the immune system. J. Immunol. 2005, 175:7781-7787.
26. van Beek E.M., de Vries T.J., Mulder L., Schoenmaker T., Hoeben K.A., Matozaki T., Langenbach G.E., Kraal G., Everts V., van den Berg T.K. Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha. FASEB J. 2009, 23:4081-4090.
27. Vernon-Wilson E.F., Kee W.J., Willis A.C., Barclay A.N., Simmons D.L., Brown M.H. CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1. Eur. J. Immunol. 2000, 30:2130-2137.
28. Yamao T., Noguchi T., Takeuchi O., Nishiyama U., Morita H., Hagiwara T., Akahori H., Kato T., Inagaki K., Okazawa H., et al. Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1. J. Biol. Chem. 2002, 277:39833-39839.
29. Zhen L., King A.A., Xiao Y., Chanock S.J., Orkin S.H., Dinauer M.C. Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox. Proc. Natl. Acad. Sci. USA 1993, 90:9832-9836.
30. Zhu C., Lindsey S., Konieczna I., Eklund E.A. Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation. J. Leukoc. Biol. 2008, 83:680-691.