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Volumn 101, Issue 12, 2012, Pages 4653-4659

Interaction of n-acetylcysteine and cysteine in human plasma

Author keywords

Albumin; Antioxidants; Bioanalysis; HPLC (high performance pressure liquid chromatography); LC MS; Pediatric; Protein binding

Indexed keywords


EID: 84868104105     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23325     Document Type: Article
Times cited : (29)

References (23)
  • 1
    • 0032881782 scopus 로고    scopus 로고
    • N-acetyl-cysteine reduces homocysteine plasma levels after single intravenous administration by increasing thiols urinary excretion
    • Ventura P, Panini R, Pasini MC, Scarpetta G, Salvioli G. 1999. N-acetyl-cysteine reduces homocysteine plasma levels after single intravenous administration by increasing thiols urinary excretion. Pharmacol Res 40(4):345-350.
    • (1999) Pharmacol Res , vol.40 , Issue.4 , pp. 345-350
    • Ventura, P.1    Panini, R.2    Pasini, M.C.3    Scarpetta, G.4    Salvioli, G.5
  • 7
    • 1642462339 scopus 로고    scopus 로고
    • Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury
    • Hart AM, Terenghi G, Kellerth JO, Wiberg M. 2004. Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury. Neuroscience 125(1):91-101.
    • (2004) Neuroscience , vol.125 , Issue.1 , pp. 91-101
    • Hart, A.M.1    Terenghi, G.2    Kellerth, J.O.3    Wiberg, M.4
  • 8
    • 34447636583 scopus 로고    scopus 로고
    • Kinetics of uptake and deacetylation of N-acetylcysteine by human erythrocytes
    • Raftos JE, Whillier S, Chapman BE, Kuchel PW. 2007. Kinetics of uptake and deacetylation of N-acetylcysteine by human erythrocytes. Int J Biochem Cell Biol 39(9):1698-1706.
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.9 , pp. 1698-1706
    • Raftos, J.E.1    Whillier, S.2    Chapman, B.E.3    Kuchel, P.W.4
  • 9
    • 0025875051 scopus 로고
    • The metabolism of N-acetylcysteine by human endothelial cells
    • Cotgreave I, Moldeus P, Schuppe I. 1991. The metabolism of N-acetylcysteine by human endothelial cells. Biochem Pharmacol 42(1):13-16.
    • (1991) Biochem Pharmacol , vol.42 , Issue.1 , pp. 13-16
    • Cotgreave, I.1    Moldeus, P.2    Schuppe, I.3
  • 10
    • 68949129086 scopus 로고    scopus 로고
    • Role of N-acetylcysteine and cystine in glutathione synthesis in human erythrocytes
    • Whillier S, Raftos JE, Chapman B, Kuchel PW. 2009. Role of N-acetylcysteine and cystine in glutathione synthesis in human erythrocytes. Redox Rep 14(3):115-124.
    • (2009) Redox Rep , vol.14 , Issue.3 , pp. 115-124
    • Whillier, S.1    Raftos, J.E.2    Chapman, B.3    Kuchel, P.W.4
  • 11
    • 0023680343 scopus 로고
    • Oxidative stresses induced the cystine transport activity in human erythrocytes
    • Ohtsuka Y, Kondo T, Kawakami Y. 1988. Oxidative stresses induced the cystine transport activity in human erythrocytes. Biochem Biophys Res Commun 155(1):160-166.
    • (1988) Biochem Biophys Res Commun , vol.155 , Issue.1 , pp. 160-166
    • Ohtsuka, Y.1    Kondo, T.2    Kawakami, Y.3
  • 12
    • 16644398454 scopus 로고    scopus 로고
    • Kinetic studies of covalent binding between N-acetyl-l-cysteine and human serum albumin through a mixed-disulfide using an N-methylpyridinium polymer-based column
    • Harada D, Anraku M, Fukuda H, Naito S, Harada K, Suenaga A, Otagiri M. 2004. Kinetic studies of covalent binding between N-acetyl-l-cysteine and human serum albumin through a mixed-disulfide using an N-methylpyridinium polymer-based column. Drug Metab Pharmacokinet 19(4):297-302.
    • (2004) Drug Metab Pharmacokinet , vol.19 , Issue.4 , pp. 297-302
    • Harada, D.1    Anraku, M.2    Fukuda, H.3    Naito, S.4    Harada, K.5    Suenaga, A.6    Otagiri, M.7
  • 13
    • 0036846825 scopus 로고    scopus 로고
    • Kinetic analysis of covalent binding between N-acetyl-l-cysteine and albumin through the formation of mixed disulfides in human and rat serum in vitro
    • Harada D, Naito S, Otagiri M. 2002. Kinetic analysis of covalent binding between N-acetyl-l-cysteine and albumin through the formation of mixed disulfides in human and rat serum in vitro. Pharm Res 19(11):1648-1654.
    • (2002) Pharm Res , vol.19 , Issue.11 , pp. 1648-1654
    • Harada, D.1    Naito, S.2    Otagiri, M.3
  • 14
    • 0035869559 scopus 로고    scopus 로고
    • Determination of reduced, protein-unbound, and total concentrations of N-acetyl-l-cysteine and l-cysteine in rat plasma by postcolumn ligand substitution high-performance liquid chromatography
    • Harada D, Naito S, Kawauchi Y, Ishikawa K, Koshitani O, Hiraoka I, Otagiri M. 2001. Determination of reduced, protein-unbound, and total concentrations of N-acetyl-l-cysteine and l-cysteine in rat plasma by postcolumn ligand substitution high-performance liquid chromatography. Anal Biochem 290(2):251-259.
    • (2001) Anal Biochem , vol.290 , Issue.2 , pp. 251-259
    • Harada, D.1    Naito, S.2    Kawauchi, Y.3    Ishikawa, K.4    Koshitani, O.5    Hiraoka, I.6    Otagiri, M.7
  • 16
    • 0021215013 scopus 로고
    • Transport of cystine and cysteine in mammalian cells
    • Bannai S. 1984. Transport of cystine and cysteine in mammalian cells. Biochim Biophys Acta 779(3):289-306.
    • (1984) Biochim Biophys Acta , vol.779 , Issue.3 , pp. 289-306
    • Bannai, S.1
  • 18
    • 0030576641 scopus 로고    scopus 로고
    • Differential distribution of free and bound glutathione and cyst(e)ine in human blood
    • Mills BJ, Lang CA. 1996. Differential distribution of free and bound glutathione and cyst(e)ine in human blood. Biochem Pharmacol 52(3):401-406.
    • (1996) Biochem Pharmacol , vol.52 , Issue.3 , pp. 401-406
    • Mills, B.J.1    Lang, C.A.2
  • 19
    • 78751574360 scopus 로고    scopus 로고
    • Oxidative stress increases SNAT1 expression and stimulates cysteine uptake in freshly isolated rat cardiomyocytes
    • King N, Lin H, Suleiman MS. 2011. Oxidative stress increases SNAT1 expression and stimulates cysteine uptake in freshly isolated rat cardiomyocytes. Amino Acids 40(2):517-526.
    • (2011) Amino Acids , vol.40 , Issue.2 , pp. 517-526
    • King, N.1    Lin, H.2    Suleiman, M.S.3
  • 22
    • 0024414168 scopus 로고
    • N-acetyl-l-tyrosine and N-acetyl-l-cysteine as tyrosine and cysteine precursors during intravenous infusion in humans
    • Magnusson I, Ekman L, Wangdahl M, Wahren J. 1989. N-acetyl-l-tyrosine and N-acetyl-l-cysteine as tyrosine and cysteine precursors during intravenous infusion in humans. Metabolism 38(10):957-961.
    • (1989) Metabolism , vol.38 , Issue.10 , pp. 957-961
    • Magnusson, I.1    Ekman, L.2    Wangdahl, M.3    Wahren, J.4
  • 23
    • 0028258621 scopus 로고
    • The utilization of N-acetylcysteine and 2-oxothiazolidine-4-carboxylate by rat hepatocytes is limited by their rate of uptake and conversion to cysteine
    • Banks MF, Stipanuk MH. 1994. The utilization of N-acetylcysteine and 2-oxothiazolidine-4-carboxylate by rat hepatocytes is limited by their rate of uptake and conversion to cysteine. J Nutr 124(3):378-387.
    • (1994) J Nutr , vol.124 , Issue.3 , pp. 378-387
    • Banks, M.F.1    Stipanuk, M.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.