-
1
-
-
0035160282
-
Effectiveness of first antiepileptic drug
-
Kwan P, Brodie MJ. Effectiveness of first antiepileptic drug. Epilepsia. 2001;42:1255-1260.
-
(2001)
Epilepsia.
, vol.42
, pp. 1255-1260
-
-
Kwan, P.1
Brodie, M.J.2
-
2
-
-
0037161362
-
Staged approach to epilepsy management
-
Brodie MJ, Kwan P. Staged approach to epilepsy management. Neurology. 2002;58:S2-S8.
-
(2002)
Neurology.
, vol.58
-
-
Brodie, M.J.1
Kwan, P.2
-
3
-
-
33746111455
-
The effect of the new antiepileptic drug rufinamide on cognitive functions
-
Aldenkamp AP, Alpherts WC. The effect of the new antiepileptic drug rufinamide on cognitive functions. Epilepsia. 2006;47:1153-1159.
-
(2006)
Epilepsia.
, vol.47
, pp. 1153-1159
-
-
Aldenkamp, A.P.1
Alpherts, W.C.2
-
4
-
-
0034950048
-
Behavioural effects of the new anticonvulsants
-
Besag FM. Behavioural effects of the new anticonvulsants. Drug Saf. 2001;24:513-536.
-
(2001)
Drug Saf.
, vol.24
, pp. 513-536
-
-
Besag, F.M.1
-
5
-
-
70350150988
-
Determinants of quality of life in people with epilepsy
-
Jacoby A, Snape D, Baker GA. Determinants of quality of life in people with epilepsy. Neurol Clin. 2009;27:843-863.
-
(2009)
Neurol Clin.
, vol.27
, pp. 843-863
-
-
Jacoby, A.1
Snape, D.2
Baker, G.A.3
-
6
-
-
34548046716
-
The impact of seizures and adverse effects on global health ratings
-
Cramer JA, Brandenburg NA, Xu X, Vera-Llonch M, Oster G. The impact of seizures and adverse effects on global health ratings. Epilepsy Behav. 2007;11:179-184.
-
(2007)
Epilepsy Behav.
, vol.11
, pp. 179-184
-
-
Cramer, J.A.1
Brandenburg, N.A.2
Xu, X.3
Vera-Llonch, M.4
Oster, G.5
-
7
-
-
0031015788
-
Severe persistent visual field constriction associated with vigabatrin
-
Eke T, Talbot JF, Lawden MC. Severe persistent visual field constriction associated with vigabatrin. BMJ. 1997;314:180-181.
-
(1997)
BMJ.
, vol.314
, pp. 180-181
-
-
Eke, T.1
Talbot, J.F.2
Lawden, M.C.3
-
8
-
-
0028526425
-
Felbamate linked to aplastic anemia; warning issued on drug's use
-
Felbamate linked to aplastic anemia; warning issued on drug's use. Am J Hosp Pharm. 1994;51(19):2324.
-
(1994)
Am J Hosp Pharm.
, vol.51
, Issue.19
, pp. 2324
-
-
-
9
-
-
0032888645
-
Felbamate in epilepsy therapy: Evaluating the risks
-
Pellock JM. Felbamate in epilepsy therapy: evaluating the risks. Drug Saf. 1999;21:225-239.
-
(1999)
Drug Saf.
, vol.21
, pp. 225-239
-
-
Pellock, J.M.1
-
10
-
-
77950839536
-
When can a drug be declared "safe"
-
Besag FM, Dodd S. When can a drug be declared "safe"? Curr Drug Saf. 2010;5:112-113.
-
(2010)
Curr Drug Saf.
, vol.5
, pp. 112-113
-
-
Besag, F.M.1
Dodd, S.2
-
11
-
-
0037006614
-
The misdiagnosis of epilepsy
-
Chadwick D, Smith D. The misdiagnosis of epilepsy. BMJ. 2002;324: 495-496.
-
(2002)
BMJ.
, vol.324
, pp. 495-496
-
-
Chadwick, D.1
Smith, D.2
-
12
-
-
33644640615
-
The misdiagnosis of epilepsy in children admitted to a tertiary epilepsy centre with paroxysmal events
-
Uldall P, Alving J, Hansen LK, Kibaek M, Buchholt J. The misdiagnosis of epilepsy in children admitted to a tertiary epilepsy centre with paroxysmal events. Arch Dis Child. 2006;91:219-221.
-
(2006)
Arch Dis Child.
, vol.91
, pp. 219-221
-
-
Uldall, P.1
Alving, J.2
Hansen, L.K.3
Kibaek, M.4
Buchholt, J.5
-
13
-
-
0035169880
-
Seizure outcome after temporal lobectomy: Current research practice and findings
-
McIntosh AM, Wilson SJ, Berkovic SF. Seizure outcome after temporal lobectomy: current research practice and findings. Epilepsia. 2001;42: 1288-1307.
-
(2001)
Epilepsia.
, vol.42
, pp. 1288-1307
-
-
McIntosh, A.M.1
Wilson, S.J.2
Berkovic, S.F.3
-
14
-
-
0035797593
-
A randomized, controlled trial of surgery for temporal-lobe epilepsy
-
Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group
-
Wiebe S, Blume WT, Girvin JP, Eliasziw M; Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group. A randomized, controlled trial of surgery for temporal-lobe epilepsy. New Engl J Med. 2001;345(5):311-318.
-
(2001)
New Engl J Med.
, vol.345
, Issue.5
, pp. 311-318
-
-
Wiebe, S.1
Blume, W.T.2
Girvin, J.P.3
Eliasziw, M.4
-
15
-
-
84860888756
-
Psychopathology in children before and after surgery for extratemporal lobe epilepsy
-
Colonnelli MC, Cross JH, Davies S, et al. Psychopathology in children before and after surgery for extratemporal lobe epilepsy. Dev Med Child Neurol. 2012;54:521-526.
-
(2012)
Dev Med Child Neurol.
, vol.54
, pp. 521-526
-
-
Colonnelli, M.C.1
Cross, J.H.2
Davies, S.3
-
16
-
-
0034061959
-
Psychiatric aspects of temporal lobe epilepsy before and after anterior temporal lobectomy
-
Glosser G, Zwil AS, Glosser DS, O'Connor MJ, Sperling MR. Psychiatric aspects of temporal lobe epilepsy before and after anterior temporal lobectomy. J Neurol Neurosurg Psychiatry. 2000;68:53-58.
-
(2000)
J Neurol Neurosurg Psychiatry.
, vol.68
, pp. 53-58
-
-
Glosser, G.1
Zwil, A.S.2
Glosser, D.S.3
O'Connor, M.J.4
Sperling, M.R.5
-
17
-
-
0031920932
-
Psychiatric outcome of temporal lobectomy for epilepsy: Incidence and treatment of psychiatric complications
-
Blumer D, Wakhlu S, Davies K, Hermann B. Psychiatric outcome of temporal lobectomy for epilepsy: incidence and treatment of psychiatric complications. Epilepsia. 1998;39:478-486.
-
(1998)
Epilepsia.
, vol.39
, pp. 478-486
-
-
Blumer, D.1
Wakhlu, S.2
Davies, K.3
Hermann, B.4
-
18
-
-
0037084471
-
Vagus nerve stimulation (VNS) for major depressive episodes: One year outcomes
-
Marangell LB, Rush AJ, George MS, et al. Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomes. Biol Psychiatry. 2002;51:280-287.
-
(2002)
Biol Psychiatry.
, vol.51
, pp. 280-287
-
-
Marangell, L.B.1
Rush, A.J.2
George, M.S.3
-
19
-
-
84859436348
-
Vagus nerve stimulation has a positive effect on mood in patients with refractory epilepsy
-
Klinkenberg S, Majoie HJ, van der Heijden MM, Rijkers K, Leenen L, Aldenkamp AP. Vagus nerve stimulation has a positive effect on mood in patients with refractory epilepsy. Clin Neurol Neurosurg. 2012;114:336-340.
-
(2012)
Clin Neurol Neurosurg.
, vol.114
, pp. 336-340
-
-
Klinkenberg, S.1
Majoie, H.J.2
van der Heijden, M.M.3
Rijkers, K.4
Leenen, L.5
Aldenkamp, A.P.6
-
20
-
-
70350041894
-
Therapeutic brain stimulation for epilepsy
-
Lockman J, Fisher RS. Therapeutic brain stimulation for epilepsy. Neurol Clin. 2009;27:1031-1040.
-
(2009)
Neurol Clin.
, vol.27
, pp. 1031-1040
-
-
Lockman, J.1
Fisher, R.S.2
-
23
-
-
0029900489
-
The first gene for an idiopathic epilepsy: A fruitful collaboration of Australian clinical research and molecular genetics [editorial]
-
Berkovic SF, Mulley JC. The first gene for an idiopathic epilepsy: a fruitful collaboration of Australian clinical research and molecular genetics [editorial]. Aust N Z J Med. 1996;26:154-156.
-
(1996)
Aust N Z J Med.
, vol.26
, pp. 154-156
-
-
Berkovic, S.F.1
Mulley, J.C.2
-
24
-
-
44349150359
-
X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment
-
Dibbens LM, Tarpey PS, Hynes K, et al. X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment. Nat Genet. 2008;40:776-781.
-
(2008)
Nat Genet.
, vol.40
, pp. 776-781
-
-
Dibbens, L.M.1
Tarpey, P.S.2
Hynes, K.3
-
25
-
-
0031947590
-
Lamotrigine and seizure aggravation in severe myoclonic epilepsy
-
Guerrini R, Dravet C, Genton P, Belmonte A, Kaminska A, Dulac O. Lamotrigine and seizure aggravation in severe myoclonic epilepsy. Epilepsia. 1998;39:508-512.
-
(1998)
Epilepsia.
, vol.39
, pp. 508-512
-
-
Guerrini, R.1
Dravet, C.2
Genton, P.3
Belmonte, A.4
Kaminska, A.5
Dulac, O.6
-
26
-
-
0026010310
-
Therapeutic trial of vigabatrin in refractory infantile spasms
-
Chiron C, Dulac O, Beaumont D, Palacios L, Pajot N, Mumford J. Therapeutic trial of vigabatrin in refractory infantile spasms. J Child Neurol. 1991;Suppl 2:S52-S59.
-
(1991)
J Child Neurol.
, Issue.SUPPL. 2
-
-
Chiron, C.1
Dulac, O.2
Beaumont, D.3
Palacios, L.4
Pajot, N.5
Mumford, J.6
-
27
-
-
58849138280
-
Epilepsy after head injury: An overview
-
Lowenstein DH. Epilepsy after head injury: an overview. Epilepsia. 2009;50 Suppl 2:4-9.
-
(2009)
Epilepsia.
, vol.50
, Issue.SUPPL. 2
, pp. 4-9
-
-
Lowenstein, D.H.1
-
28
-
-
0031030374
-
Imaging and epilepsy
-
Duncan JS. Imaging and epilepsy. Brain. 1997;120:339-377.
-
(1997)
Brain.
, vol.120
, pp. 339-377
-
-
Duncan, J.S.1
-
29
-
-
79960360564
-
Autoantibodies associated with diseases of the CNS: New developments and future challenges
-
Vincent A, Bien CG, Irani SR, Waters P. Autoantibodies associated with diseases of the CNS: new developments and future challenges. Lancet Neurol. 2011;10:759-772.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 759-772
-
-
Vincent, A.1
Bien, C.G.2
Irani, S.R.3
Waters, P.4
-
30
-
-
33746124186
-
ILAE treatment guidelines: Evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes
-
Glauser T, Ben-Menachem E, Bourgeois B, et al. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia. 2006;47:1094-1120.
-
(2006)
Epilepsia.
, vol.47
, pp. 1094-1120
-
-
Glauser, T.1
Ben-Menachem, E.2
Bourgeois, B.3
-
31
-
-
84991217147
-
The epilepsies: The diagnosis and management of the epilepsies in adults and children in primary and secondary care
-
National Institute for Health and Clinical Excellence, Issued: Jan, Available from, Accessed August 19, 2012
-
National Institute for Health and Clinical Excellence. The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. NICE clinical guideline 137. Issued: Jan 2012. Available from: http://guidance.nice.org.uk/CG137. Accessed August 19, 2012.
-
(2012)
NICE clinical guideline 137
-
-
-
32
-
-
0028021837
-
Cognitive side-effects of phenytoin compared with carbamazepine in patients with localization-related epilepsy
-
Aldenkamp AP, Alpherts WCJ, Diepman L, Van't Slot B, Overweg J, Vermeulen J. Cognitive side-effects of phenytoin compared with carbamazepine in patients with localization-related epilepsy. Epilepsy Res. 1994;19:37-43.
-
(1994)
Epilepsy Res.
, vol.19
, pp. 37-43
-
-
Aldenkamp, A.P.1
Alpherts, W.C.J.2
Diepman, L.3
Van't Slot, B.4
Overweg, J.5
Vermeulen, J.6
-
33
-
-
33750113486
-
The spectrum of valproic acid-associated pancreatitis
-
Werlin SL, Fish DL. The spectrum of valproic acid-associated pancreatitis. Pediatrics. 2006;118:1660-1663.
-
(2006)
Pediatrics.
, vol.118
, pp. 1660-1663
-
-
Werlin, S.L.1
Fish, D.L.2
-
34
-
-
32344440085
-
Malformation risks of antiepileptic drugs in pregnancy: A prospective study from the UK Epilepsy and Pregnancy Register
-
Morrow J, Russell A, Guthrie E, et al. Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry. 2006;77:193-198.
-
(2006)
J Neurol Neurosurg Psychiatry.
, vol.77
, pp. 193-198
-
-
Morrow, J.1
Russell, A.2
Guthrie, E.3
-
35
-
-
7244257375
-
The longer term outcome of children born to mothers with epilepsy
-
Adab N, Kini U, Vinten J, et al. The longer term outcome of children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry. 2004;75:1575-1583.
-
(2004)
J Neurol Neurosurg Psychiatry.
, vol.75
, pp. 1575-1583
-
-
Adab, N.1
Kini, U.2
Vinten, J.3
-
36
-
-
64749112939
-
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs
-
Meador KJ, Baker GA, Browning N, et al. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N Engl J Med. 2009; 360:1597-1605.
-
(2009)
N Engl J Med.
, vol.360
, pp. 1597-1605
-
-
Meador, K.J.1
Baker, G.A.2
Browning, N.3
-
37
-
-
7044271164
-
Zonisamide: Chemistry, mechanism of action, and pharmacokinetics
-
Leppik IE. Zonisamide: chemistry, mechanism of action, and pharmacokinetics. Seizure. 2004;13 Suppl 1:S5-S9.
-
(2004)
Seizure.
, vol.13
, Issue.SUPPL. 1
-
-
Leppik, I.E.1
-
38
-
-
77955451598
-
Zonisamide discontinuation due to psychiatric and cognitive adverse events: A case-control study
-
White JR, Walczak TS, Marino SE, Beniak TE, Leppik IE, Birnbaum AK. Zonisamide discontinuation due to psychiatric and cognitive adverse events: a case-control study. Neurology. 2010;75:513-518.
-
(2010)
Neurology.
, vol.75
, pp. 513-518
-
-
White, J.R.1
Walczak, T.S.2
Marino, S.E.3
Beniak, T.E.4
Leppik, I.E.5
Birnbaum, A.K.6
-
39
-
-
0029831493
-
Update on the mechanism of action of antiepileptic drugs
-
Meldrum BS. Update on the mechanism of action of antiepileptic drugs. Epilepsia. 1996;37 Suppl 6:S4-S11.
-
(1996)
Epilepsia.
, vol.37
, Issue.SUPPL. 6
-
-
Meldrum, B.S.1
-
40
-
-
0031414052
-
Antiepileptic drug cellular mechanisms of action: Where does lamotrigine fit in
-
Coulter DA. Antiepileptic drug cellular mechanisms of action: where does lamotrigine fit in? J Child Neurol. 1997;12 Suppl 1:S2-S9.
-
(1997)
J Child Neurol.
, vol.12
, Issue.SUPPL. 1
-
-
Coulter, D.A.1
-
41
-
-
78149248492
-
The anticonvulsive drug lamotrigine blocks neuronal {alpha}4{beta}2 nicotinic acetylcholine receptors
-
Zheng C, Yang K, Liu Q, etal. The anticonvulsive drug lamotrigine blocks neuronal {alpha}4{beta}2 nicotinic acetylcholine receptors. J Pharmacol Exp Ther. 2010;335:401-408.
-
(2010)
J Pharmacol Exp Ther.
, vol.335
, pp. 401-408
-
-
Zheng, C.1
Yang, K.2
Liu, Q.3
et al4
-
42
-
-
33947241772
-
The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: An unblinded randomised controlled trial
-
Marson AG, Al-Kharusi AM, Alwaidh M, et al. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet. 2007;369:1000-1015.
-
(2007)
Lancet.
, vol.369
, pp. 1000-1015
-
-
Marson, A.G.1
Al-Kharusi, A.M.2
Alwaidh, M.3
-
43
-
-
0342301745
-
Lamotrigine-associated rash: Risk/benefit considerations in adults and children
-
Guberman AH, Besag FM, Brodie MJ, et al. Lamotrigine-associated rash: risk/benefit considerations in adults and children. Epilepsia. 1999;40:985-991.
-
(1999)
Epilepsia.
, vol.40
, pp. 985-991
-
-
Guberman, A.H.1
Besag, F.M.2
Brodie, M.J.3
-
45
-
-
0028142808
-
Oxcarbazepine: Preclinical anticonvulsant profile and putative mechanisms of action
-
Schmutz M, Brugger F, Gentsch C, McLean MJ, Olpe HR. Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action. Epilepsia. 1994;35 Suppl 5:S47-S50.
-
(1994)
Epilepsia.
, vol.35
, Issue.SUPPL. 5
-
-
Schmutz, M.1
Brugger, F.2
Gentsch, C.3
McLean, M.J.4
Olpe, H.R.5
-
47
-
-
0028008995
-
Mechanism of action of the anticonvulsant felbamate: Opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors
-
Rho JM, Donevan SD, Rogawski MA. Mechanism of action of the anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors. Ann Neurol. 1994;35: 229-234.
-
(1994)
Ann Neurol.
, vol.35
, pp. 229-234
-
-
Rho, J.M.1
Donevan, S.D.2
Rogawski, M.A.3
-
48
-
-
0029975930
-
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel
-
Gee NS, Brown JP, Dissanayake VU, Offord J, Thurlow R, Woodruff GN. The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel. J Biol Chem. 1996;271: 5768-5776.
-
(1996)
J Biol Chem.
, vol.271
, pp. 5768-5776
-
-
Gee, N.S.1
Brown, J.P.2
Dissanayake, V.U.3
Offord, J.4
Thurlow, R.5
Woodruff, G.N.6
-
49
-
-
0029887507
-
The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine
-
Perucca E, Bialer M. The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine. Clin Pharmacokinet. 1996;31:29-46.
-
(1996)
Clin Pharmacokinet.
, vol.31
, pp. 29-46
-
-
Perucca, E.1
Bialer, M.2
-
50
-
-
0033816145
-
A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures
-
Aldenkamp AP, Baker G, Mulder OG, et al. A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures. Epilepsia. 2000;41:1167-1178.
-
(2000)
Epilepsia.
, vol.41
, pp. 1167-1178
-
-
Aldenkamp, A.P.1
Baker, G.2
Mulder, O.G.3
-
52
-
-
79960552387
-
Pregabalin is a potent and selective ligand for α(2)δ-1 and α(2)δ-2calcium channel subunits
-
Li Z, Taylor CP, Weber M, etal. Pregabalin is a potent and selective ligand for α(2)δ-1 and α(2)δ-2calcium channel subunits. Eur J Pharmacol. 2011;667:80-90.
-
(2011)
Eur J Pharmacol.
, vol.667
, pp. 80-90
-
-
Li, Z.1
Taylor, C.P.2
Weber, M.3
et al4
-
54
-
-
76049084221
-
A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures
-
Elger CE, Stefan H, Mann A, Narurkar M, Sun Y, Perdomo C. A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures. Epilepsy Res. 2010;88:255-263.
-
(2010)
Epilepsy Res.
, vol.88
, pp. 255-263
-
-
Elger, C.E.1
Stefan, H.2
Mann, A.3
Narurkar, M.4
Sun, Y.5
Perdomo, C.6
-
55
-
-
0021321230
-
A new type of anticonvulsant, stiripentol. Pharmacological profile and neurochemical study
-
Poisson M, Huguet F, Savattier A, Bakri-Logeais F, Narcisse G. A new type of anticonvulsant, stiripentol. Pharmacological profile and neurochemical study. Arzneimittelforschung. 1984;34:199-204.
-
(1984)
Arzneimittelforschung.
, vol.34
, pp. 199-204
-
-
Poisson, M.1
Huguet, F.2
Savattier, A.3
Bakri-Logeais, F.4
Narcisse, G.5
-
56
-
-
33645106149
-
In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism
-
Giraud C, Treluyer JM, Rey E, et al. In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism. Drug Metab Dispos. 2006;34: 608-611.
-
(2006)
Drug Metab Dispos.
, vol.34
, pp. 608-611
-
-
Giraud, C.1
Treluyer, J.M.2
Rey, E.3
-
57
-
-
80155168901
-
Novel medications for epilepsy
-
Fattore C, Perucca E. Novel medications for epilepsy. Drugs. 2011;71: 2151-2178.
-
(2011)
Drugs.
, vol.71
, pp. 2151-2178
-
-
Fattore, C.1
Perucca, E.2
-
58
-
-
84858641737
-
Pharmacotherapy of the third-generation AEDs: Lacosamide, retigabine and eslicarbazepine acetate
-
Patsalos PN, Berry DJ. Pharmacotherapy of the third-generation AEDs: lacosamide, retigabine and eslicarbazepine acetate. Expert Opin Pharmacother. 2012;13:699-715.
-
(2012)
Expert Opin Pharmacother.
, vol.13
, pp. 699-715
-
-
Patsalos, P.N.1
Berry, D.J.2
-
59
-
-
61849168486
-
Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double-blind, placebo-controlled, parallel-group phase III study
-
Investigators Study Group
-
Elger C, Halasz P, Maia J, Almeida L, Soares-da-Silva P; Investigators Study Group. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study. Epilepsia. 2009;50:454-463.
-
(2009)
Epilepsia.
, vol.50
, pp. 454-463
-
-
Elger, C.1
Halasz, P.2
Maia, J.3
Almeida, L.4
Soares-da-Silva, P.5
-
60
-
-
70349972675
-
Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures
-
Investigators Study Group
-
Gil-Nagel A, Lopes-Lima J, Almeida L, Maia J, Soares-da-Silva P; Investigators Study Group. Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. Acta Neurol Scand. 2009;120:281-287.
-
(2009)
Acta Neurol Scand.
, vol.120
, pp. 281-287
-
-
Gil-Nagel, A.1
Lopes-Lima, J.2
Almeida, L.3
Maia, J.4
Soares-da-Silva, P.5
-
61
-
-
77951297857
-
Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy
-
Ben-Menachem E, Gabbai AA, Hufnagel A, Maia J, Almeida L, Soares-da-Silva P. Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy. Epilepsy Res. 2010;89:278-285.
-
(2010)
Epilepsy Res.
, vol.89
, pp. 278-285
-
-
Ben-Menachem, E.1
Gabbai, A.A.2
Hufnagel, A.3
Maia, J.4
Almeida, L.5
Soares-da-Silva, P.6
-
62
-
-
37349071555
-
The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels
-
Errington AC, Stohr T, Heers C, Lees G. The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Mol Pharmacol. 2008;73:157-169.
-
(2008)
Mol Pharmacol.
, vol.73
, pp. 157-169
-
-
Errington, A.C.1
Stohr, T.2
Heers, C.3
Lees, G.4
-
63
-
-
77953033494
-
Lacosamide as adjunctive therapy for partial-onset seizures: A randomized controlled trial
-
Chung S, Sperling MR, Biton V, et al. Lacosamide as adjunctive therapy for partial-onset seizures: a randomized controlled trial. Epilepsia. 2010; 51:958-967.
-
(2010)
Epilepsia.
, vol.51
, pp. 958-967
-
-
Chung, S.1
Sperling, M.R.2
Biton, V.3
-
64
-
-
78649339546
-
Examining the clinical utility of lacosamide: Pooled analyses of three phase II/III clinical trials
-
Chung S, Ben-Menachem E, Sperling MR, et al. Examining the clinical utility of lacosamide: pooled analyses of three phase II/III clinical trials. CNS Drugs. 2010;24:1041-1054.
-
(2010)
CNS Drugs.
, vol.24
, pp. 1041-1054
-
-
Chung, S.1
Ben-Menachem, E.2
Sperling, M.R.3
-
65
-
-
0033916576
-
Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine
-
Main MJ, Cryan JE, Dupere JR, Cox B, Clare JJ, Burbidge SA. Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine. Mol Pharmacol. 2000;58:253-262.
-
(2000)
Mol Pharmacol.
, vol.58
, pp. 253-262
-
-
Main, M.J.1
Cryan, J.E.2
Dupere, J.R.3
Cox, B.4
Clare, J.J.5
Burbidge, S.A.6
-
66
-
-
15744400656
-
The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate
-
Wuttke TV, Seebohm G, Bail S, Maljevic S, Lerche H. The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate. Mol Pharmacol. 2005;67:1009-1017.
-
(2005)
Mol Pharmacol.
, vol.67
, pp. 1009-1017
-
-
Wuttke, T.V.1
Seebohm, G.2
Bail, S.3
Maljevic, S.4
Lerche, H.5
-
68
-
-
34247252905
-
Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures
-
Study Group
-
Porter RJ, Partiot A, Sachdeo R, Nohria V, Alves WM; Study Group. Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures. Neurology. 2007;68:1197-1204.
-
(2007)
Neurology.
, vol.68
, pp. 1197-1204
-
-
Porter, R.J.1
Partiot, A.2
Sachdeo, R.3
Nohria, V.4
Alves, W.M.5
-
69
-
-
78649984382
-
Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy
-
Brodie MJ, Lerche H, Gil-Nagel A, etal. Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy. Neurology. 2010;75:1817-1824.
-
(2010)
Neurology.
, vol.75
, pp. 1817-1824
-
-
Brodie, M.J.1
Lerche, H.2
Gil-Nagel, A.3
et al4
-
70
-
-
79955592696
-
Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy
-
French JA, Abou-Khalil BW, Leroy RF, et al. Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy. Neurology. 2011;76:1555-1563.
-
(2011)
Neurology.
, vol.76
, pp. 1555-1563
-
-
French, J.A.1
Abou-Khalil, B.W.2
Leroy, R.F.3
-
71
-
-
84856685605
-
Revisiting AMPA receptors as an antiepileptic drug target
-
Rogawski MA. Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Curr. 2011;11:56-63.
-
(2011)
Epilepsy Curr.
, vol.11
, pp. 56-63
-
-
Rogawski, M.A.1
-
72
-
-
0027374877
-
The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy
-
Sveinbjornsdottir S, Sander JW, Upton D, et al. The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy. Epilepsy Res. 1993;16:165-174.
-
(1993)
Epilepsy Res.
, vol.16
, pp. 165-174
-
-
Sveinbjornsdottir, S.1
Sander, J.W.2
Upton, D.3
-
73
-
-
33947188651
-
Effect of novel AMPA antagonist, NS1209, on status epilepticus. An experimental study in rat
-
Pitkanen A, Mathiesen C, Ronn LC, Moller A, Nissinen J. Effect of novel AMPA antagonist, NS1209, on status epilepticus. An experimental study in rat. Epilepsy Res. 2007;74:45-54.
-
(2007)
Epilepsy Res.
, vol.74
, pp. 45-54
-
-
Pitkanen, A.1
Mathiesen, C.2
Ronn, L.C.3
Moller, A.4
Nissinen, J.5
-
74
-
-
76249098898
-
Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466
-
Fritsch B, Stott JJ, Joelle DJ, Rogawski MA. Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. Epilepsia. 2010;51:108-117.
-
(2010)
Epilepsia.
, vol.51
, pp. 108-117
-
-
Fritsch, B.1
Stott, J.J.2
Joelle, D.J.3
Rogawski, M.A.4
-
75
-
-
0033800566
-
Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents-toward an understanding of their favorable tolerability
-
Rogawski MA. Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents-toward an understanding of their favorable tolerability. Amino Acids. 2000;19:133-149.
-
(2000)
Amino Acids.
, vol.19
, pp. 133-149
-
-
Rogawski, M.A.1
-
76
-
-
0038680366
-
Talampanel, a new antiepileptic drug: Single-and multiple-dose pharmacokinetics and initial 1-week experience in patients with chronic intractable epilepsy
-
Langan YM, Lucas R, Jewell H, et al. Talampanel, a new antiepileptic drug: single-and multiple-dose pharmacokinetics and initial 1-week experience in patients with chronic intractable epilepsy. Epilepsia. 2003;44:46-53.
-
(2003)
Epilepsia.
, vol.44
, pp. 46-53
-
-
Langan, Y.M.1
Lucas, R.2
Jewell, H.3
-
77
-
-
79959970405
-
Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy
-
Hanada T, Hashizume Y, Tokuhara N, et al. Perampanel: a novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy. Epilepsia. 2011;52:1331-1340.
-
(2011)
Epilepsia.
, vol.52
, pp. 1331-1340
-
-
Hanada, T.1
Hashizume, Y.2
Tokuhara, N.3
-
78
-
-
84155186559
-
Tolerability and safety of perampanel: Two randomized dose-escalation studies
-
Krauss GL, Bar M, Biton V, et al. Tolerability and safety of perampanel: two randomized dose-escalation studies. Acta Neurol Scand. 2012;125:8-15.
-
(2012)
Acta Neurol Scand.
, vol.125
, pp. 8-15
-
-
Krauss, G.L.1
Bar, M.2
Biton, V.3
-
79
-
-
84865730251
-
Use of perampanel, a selective, non-competitive AMPA receptor antagonist, as adjunctive therapy in patients with refractory partial onset seizures: Results of a global phase III study
-
French J, Elger C, Goldberg-Stern H. Use of perampanel, a selective, non-competitive AMPA receptor antagonist, as adjunctive therapy in patients with refractory partial onset seizures: results of a global phase III study. Epilepsia. 2011;52:10.
-
(2011)
Epilepsia.
, vol.52
, pp. 10
-
-
French, J.1
Elger, C.2
Goldberg-Stern, H.3
-
80
-
-
84860755687
-
Randomised phase III study 306: Adjunctive perampanel for refractory partial-onset seizures
-
Krauss GL, Serratosa JM, Villanueva V, et al. Randomised phase III study 306: adjunctive perampanel for refractory partial-onset seizures. Neurology. 2012;78:1408-1415.
-
(2012)
Neurology.
, vol.78
, pp. 1408-1415
-
-
Krauss, G.L.1
Serratosa, J.M.2
Villanueva, V.3
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