메뉴 건너뛰기




Volumn 33, Issue 5, 2012, Pages 1385-1392

The p53-independent induction of apoptosis in breast cancer cells in response to proteasome inhibitor bortezomib

Author keywords

Apoptosis; Bortezomib; Cancer; Caspase; p53; Proteasome

Indexed keywords

BEVACIZUMAB; CASPASE 3; DNA; HEAT SHOCK PROTEIN 27; PROTEASOME; PROTEIN BAD; PROTEIN MCL 1; PROTEIN NOXA; PROTEIN P53; PUMA PROTEIN; UBIQUITIN;

EID: 84868091512     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-012-0386-3     Document Type: Article
Times cited : (50)

References (34)
  • 1
    • 34047218911 scopus 로고    scopus 로고
    • Programs for cell deathapoptosis is only one way to go
    • 17361099 10.4161/cc.6.6.3990 1:CAS:528:DC%2BD2sXnvFCltLc%3D
    • Blank M, Shiloh Y. Programs for cell deathapoptosis is only one way to go. Cell Cycle. 2007;6(6):686-95.
    • (2007) Cell Cycle , vol.6 , Issue.6 , pp. 686-695
    • Blank, M.1    Shiloh, Y.2
  • 2
    • 27644504634 scopus 로고    scopus 로고
    • How many ways to die? How many different models of cell death?
    • 16247490 10.1038/sj.cdd.4401781 1:CAS:528:DC%2BD2MXhtFCjt7%2FF
    • Melino G, Knight RA, Nicotera P. How many ways to die? How many different models of cell death? Cell Death Differ. 2005;12:1457-62.
    • (2005) Cell Death Differ , vol.12 , pp. 1457-1462
    • Melino, G.1    Knight, R.A.2    Nicotera, P.3
  • 3
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • 4561027 10.1038/bjc.1972.33 1:STN:280:DyaE3s%2FgsFSksw%3D%3D
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 1972;26(4):239-57.
    • (1972) Br J Cancer , vol.26 , Issue.4 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 4
    • 0242319666 scopus 로고    scopus 로고
    • Apoptosisthe p53 network
    • 12972501 10.1242/jcs.00739 1:CAS:528:DC%2BD3sXovFWmsLg%3D
    • Haupt S, Berger M, Goldberg Z, Haupt Y. Apoptosisthe p53 network. J Cell Sci. 2003;116(20):4077-85.
    • (2003) J Cell Sci , vol.116 , Issue.20 , pp. 4077-4085
    • Haupt, S.1    Berger, M.2    Goldberg, Z.3    Haupt, Y.4
  • 5
    • 0030962262 scopus 로고    scopus 로고
    • P53-dependent induction of apoptosis by proteasome inhibitors
    • 9148891 10.1074/jbc.272.20.12893 1:CAS:528:DyaK2sXjtlamsrw%3D
    • Lopes UG, Erhardt P, Yao R, Cooper GM. p53-dependent induction of apoptosis by proteasome inhibitors. J Biol Chem. 1997;272(20):12893-6.
    • (1997) J Biol Chem , vol.272 , Issue.20 , pp. 12893-12896
    • Lopes, U.G.1    Erhardt, P.2    Yao, R.3    Cooper, G.M.4
  • 6
    • 0029952441 scopus 로고    scopus 로고
    • In vivo ubiquitination and proteasome-mediated degradation of p53
    • 8653711 1:CAS:528:DyaK28XjtlCgu70%3D
    • Maki CG, Huibregtse JM, Howley PM. In vivo ubiquitination and proteasome-mediated degradation of p53. Cancer Res. 1996;56(11):2649-54.
    • (1996) Cancer Res , vol.56 , Issue.11 , pp. 2649-2654
    • Maki, C.G.1    Huibregtse, J.M.2    Howley, P.M.3
  • 7
    • 12844268203 scopus 로고    scopus 로고
    • Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: Role of oxidative stress
    • 15678128 10.1038/sj.jcbfm.9600028 1:CAS:528:DC%2BD2MXitFOis7s%3D
    • Saito A, Hayashi T, Okuno S, Nishi T, Chan PH. Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress. J Cereb Blood Flow Metab. 2005;25(2):267-80.
    • (2005) J Cereb Blood Flow Metab , vol.25 , Issue.2 , pp. 267-280
    • Saito, A.1    Hayashi, T.2    Okuno, S.3    Nishi, T.4    Chan, P.H.5
  • 8
    • 10644270921 scopus 로고    scopus 로고
    • P73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
    • 15601819 10.1101/gad.1221004 1:CAS:528:DC%2BD2MXhtFansw%3D%3D
    • Urist M, Tanaka T, Poyurovsky MV, Prives C. p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev. 2004;18(24):3041-54.
    • (2004) Genes Dev , vol.18 , Issue.24 , pp. 3041-3054
    • Urist, M.1    Tanaka, T.2    Poyurovsky, M.V.3    Prives, C.4
  • 9
    • 0034896331 scopus 로고    scopus 로고
    • P53-independent induction of apoptosis in human melanoma cells by a bcl-2/bcl-xL bispecific antisense oligonucleotide
    • 11350916 1:CAS:528:DC%2BD3MXktlelsL4%3D
    • Rieber MS, Zangemeister-Wittke U, Rieber M. P53-independent induction of apoptosis in human melanoma cells by a bcl-2/bcl-xL bispecific antisense oligonucleotide. Clin Cancer Res. 2001;7(5):1446-51.
    • (2001) Clin Cancer Res , vol.7 , Issue.5 , pp. 1446-1451
    • Rieber, M.S.1    Zangemeister-Wittke, U.2    Rieber, M.3
  • 10
    • 77954338545 scopus 로고    scopus 로고
    • Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons
    • 20477944 10.1111/j.1471-4159.2010.06804.x 1:CAS:528:DC%2BC3cXpslygtbk%3D
    • Fricker M, Papadia S, Hardingham GE, Tolkovsky AM. Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons. J Neurochem. 2010;114(3):772-83.
    • (2010) J Neurochem , vol.114 , Issue.3 , pp. 772-783
    • Fricker, M.1    Papadia, S.2    Hardingham, G.E.3    Tolkovsky, A.M.4
  • 11
    • 33646407310 scopus 로고    scopus 로고
    • MG132 induced apoptosis is associated with p53-independent induction of pro-apoptotic Noxa and transcriptional activity of beta-catenin
    • 16673057 10.1007/s10495-006-4990-9 1:STN:280:DC%2BD283ksl2rtw%3D%3D
    • Jullig M, Zhang WV, Ferreira A, Stott NS. MG132 induced apoptosis is associated with p53-independent induction of pro-apoptotic Noxa and transcriptional activity of beta-catenin. Apoptosis. 2006;11(4):627-41.
    • (2006) Apoptosis , vol.11 , Issue.4 , pp. 627-641
    • Jullig, M.1    Zhang, W.V.2    Ferreira, A.3    Stott, N.S.4
  • 12
    • 0036497307 scopus 로고    scopus 로고
    • P53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA
    • 11911839 10.1016/S0006-2952(02)00839-0 1:CAS:528:DC%2BD38XitFWlsr0%3D
    • Kim SG, Ravi G, Hoffmann C, Jung YJ, Kim M, Chen A, et al. p53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA. Biochem Pharmacol. 2002;63(5):871-80.
    • (2002) Biochem Pharmacol , vol.63 , Issue.5 , pp. 871-880
    • Kim, S.G.1    Ravi, G.2    Hoffmann, C.3    Jung, Y.J.4    Kim, M.5    Chen, A.6
  • 13
    • 83055179401 scopus 로고    scopus 로고
    • P53-Independent up-regulation of a TRAIL receptor DR5 by proteasome inhibitors: A mechanism for proteasome inhibitor-enhanced TRAIL-induced apoptosis
    • 22120628 10.1016/j.bbrc.2011.11.053 1:CAS:528:DC%2BC3MXhs1Sgsr%2FI
    • Seol DW. p53-Independent up-regulation of a TRAIL receptor DR5 by proteasome inhibitors: a mechanism for proteasome inhibitor-enhanced TRAIL-induced apoptosis. Biochem Biophys Res Commun. 2011;416(1-2):222-5.
    • (2011) Biochem Biophys Res Commun , vol.416 , Issue.1-2 , pp. 222-225
    • Seol, D.W.1
  • 15
    • 56249093455 scopus 로고    scopus 로고
    • Vagotomy enhances experimental metastases of 4THMpc breast cancer cells and alters substance P level
    • 18499282 10.1016/j.regpep.2008.03.012 1:CAS:528:DC%2BD1cXhsVWrsLzP
    • Erin N, Akdas Barkan G, Harms JF, Clawson GA. Vagotomy enhances experimental metastases of 4THMpc breast cancer cells and alters substance P level. Regul Pept. 2008;151(1-3):35-42.
    • (2008) Regul Pept , vol.151 , Issue.1-3 , pp. 35-42
    • Erin, N.1    Akdas Barkan, G.2    Harms, J.F.3    Clawson, G.A.4
  • 16
    • 0031004205 scopus 로고    scopus 로고
    • Apoptosis and metastasis: Increased apoptosis resistance of metastatic cancer cells is associated with the profound deficiency of apoptosis execution mechanisms
    • 9149123 10.1016/S0304-3835(97)04738-1 1:CAS:528:DyaK2sXislegsrk%3D
    • Glinsky GV, Glinsky VV, Ivanova AB, Hueser CJ. Apoptosis and metastasis: increased apoptosis resistance of metastatic cancer cells is associated with the profound deficiency of apoptosis execution mechanisms. Cancer Lett. 1997;115(2):185-93.
    • (1997) Cancer Lett , vol.115 , Issue.2 , pp. 185-193
    • Glinsky, G.V.1    Glinsky, V.V.2    Ivanova, A.B.3    Hueser, C.J.4
  • 17
    • 65449166841 scopus 로고    scopus 로고
    • Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade
    • 1:CAS:528:DC%2BD1MXks1SqtQ%3D%3D
    • Yerlikaya A, Erin N. Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade. Intl J Mol Med. 2008;22(6):817-23.
    • (2008) Intl J Mol Med , vol.22 , Issue.6 , pp. 817-823
    • Yerlikaya, A.1    Erin, N.2
  • 18
    • 0028127960 scopus 로고
    • Cytotoxic efficacy of 9-nitrocamptothecin in the treatment of human malignant melanoma cells in vitro
    • 8306340 1:CAS:528:DyaK2cXitVyjt74%3D
    • Pantazis P, Early JA, Mendoza JT, DeJesus AR, Giovanella BC. Cytotoxic efficacy of 9-nitrocamptothecin in the treatment of human malignant melanoma cells in vitro. Cancer Res. 1994;54(3):771-6.
    • (1994) Cancer Res , vol.54 , Issue.3 , pp. 771-776
    • Pantazis, P.1    Early, J.A.2    Mendoza, J.T.3    Dejesus, A.R.4    Giovanella, B.C.5
  • 19
    • 35348878567 scopus 로고    scopus 로고
    • Bortezomib induces apoptosis of Epstein-Barr virus (EBV)-transformed B cells and prolongs survival of mice inoculated with EBV-transformed B cells
    • 17626072 10.1128/JVI.02241-06 1:CAS:528:DC%2BD2sXhtVehtL7N
    • Zou P, Kawada J, Pesnicak L, Cohen JI. Bortezomib induces apoptosis of Epstein-Barr virus (EBV)-transformed B cells and prolongs survival of mice inoculated with EBV-transformed B cells. J Virol. 2007;81(18):10029-36.
    • (2007) J Virol , vol.81 , Issue.18 , pp. 10029-10036
    • Zou, P.1    Kawada, J.2    Pesnicak, L.3    Cohen, J.I.4
  • 20
    • 4644328614 scopus 로고    scopus 로고
    • Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell line
    • 15197486 10.1007/s00280-004-0811-4 1:CAS:528:DC%2BD2cXntV2ht78%3D
    • Mortenson MM, Schlieman MG, Virudachalam S, Bold RJ. Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell line. Cancer Chemother Pharmacol. 2004;54(4):343-53.
    • (2004) Cancer Chemother Pharmacol , vol.54 , Issue.4 , pp. 343-353
    • Mortenson, M.M.1    Schlieman, M.G.2    Virudachalam, S.3    Bold, R.J.4
  • 21
    • 0035072563 scopus 로고    scopus 로고
    • P53-dependent apoptosis induced by proteasome inhibition in mammary epithelial cells
    • 11319603 10.1038/sj.cdd.4400801 1:CAS:528:DC%2BD3MXjsVSgsLc%3D
    • MacLaren AP, Chapman RS, Wyllie AH, Watson CJ. p53-dependent apoptosis induced by proteasome inhibition in mammary epithelial cells. Cell Death Differ. 2001;8(3):210-8.
    • (2001) Cell Death Differ , vol.8 , Issue.3 , pp. 210-218
    • MacLaren, A.P.1    Chapman, R.S.2    Wyllie, A.H.3    Watson, C.J.4
  • 22
    • 0030886975 scopus 로고    scopus 로고
    • P53-independent apoptosis induced by paclitaxel through an indirect mechanism
    • 9275183 10.1073/pnas.94.18.9679 1:CAS:528:DyaK2sXlvVWjsb0%3D
    • Lanni JS, Lowe SW, Licitra EJ, Liu JO, Jacks T. p53-independent apoptosis induced by paclitaxel through an indirect mechanism. Proc Natl Acad Sci USA. 1997;94(18):9679-83.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.18 , pp. 9679-9683
    • Lanni, J.S.1    Lowe, S.W.2    Licitra, E.J.3    Liu, J.O.4    Jacks, T.5
  • 23
    • 68949221698 scopus 로고    scopus 로고
    • P53-Independent apoptosis limits DNA damage-Induced aneuploidy
    • 19364807 10.1534/genetics.109.102327 1:CAS:528:DC%2BD1MXosFGjt7c%3D
    • McNamee LM, Brodsky MH. p53-Independent apoptosis limits DNA damage-Induced aneuploidy. Genetics. 2009;182(2):423-35.
    • (2009) Genetics , vol.182 , Issue.2 , pp. 423-435
    • McNamee, L.M.1    Brodsky, M.H.2
  • 24
    • 79251473091 scopus 로고    scopus 로고
    • Proteasome inhibitors induce p53-independent apoptosis in human cancer cells
    • 21224072 10.1016/j.ajpath.2010.11.010 1:CAS:528:DC%2BC3MXitFGjsb4%3D
    • Pandit B, Gartel AL. Proteasome inhibitors induce p53-independent apoptosis in human cancer cells. Am J Pathol. 2011;178(1):355-60.
    • (2011) Am J Pathol , vol.178 , Issue.1 , pp. 355-360
    • Pandit, B.1    Gartel, A.L.2
  • 25
    • 0033920566 scopus 로고    scopus 로고
    • Protease inhibitor-induced apoptosis: Accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition
    • 10914553 10.1038/sj.leu.2401812 1:CAS:528:DC%2BD3cXls1Oitbg%3D
    • An WG, Hwang SG, Trepel JB, Blagosklonny MV. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia. 2000;14(7):1276-83.
    • (2000) Leukemia , vol.14 , Issue.7 , pp. 1276-1283
    • An, W.G.1    Hwang, S.G.2    Trepel, J.B.3    Blagosklonny, M.V.4
  • 26
    • 30144442233 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
    • 16166592 10.1182/blood-2005-05-2091 1:CAS:528:DC%2BD28XhsVGmuw%3D%3D
    • Perez-Galan P, Roue G, Villamor N, Montserrat E, Campo E, Colomer D. The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood. 2006;107(1):257-64.
    • (2006) Blood , vol.107 , Issue.1 , pp. 257-264
    • Perez-Galan, P.1    Roue, G.2    Villamor, N.3    Montserrat, E.4    Campo, E.5    Colomer, D.6
  • 27
    • 58549114211 scopus 로고    scopus 로고
    • Bortezomib-induced apoptosis in mature T-cell lymphoma cells partially depends on upregulation of Noxa and functional repression of Mcl-1
    • 19068089 10.1111/j.1349-7006.2008.01038.x 1:CAS:528:DC%2BD1MXhvVylsLo%3D
    • Ri M, Iida S, Ishida T, Ito A, Yano H, Inagaki A, et al. Bortezomib-induced apoptosis in mature T-cell lymphoma cells partially depends on upregulation of Noxa and functional repression of Mcl-1. Cancer Sci. 2009;100(2):341-8.
    • (2009) Cancer Sci. , vol.100 , Issue.2 , pp. 341-348
    • Ri, M.1    Iida, S.2    Ishida, T.3    Ito, A.4    Yano, H.5    Inagaki, A.6
  • 28
    • 42049110004 scopus 로고    scopus 로고
    • Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways
    • 18398749 10.1080/10428190801910912 1:CAS:528:DC%2BD1cXksFaqsbg%3D
    • Rizzatti EG, Mora-Jensen H, Weniger MA, Gibellini F, Lee E, Daibata M, et al. Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways. Leuk Lymphoma. 2008;49(4):798-808.
    • (2008) Leuk Lymphoma , vol.49 , Issue.4 , pp. 798-808
    • Rizzatti, E.G.1    Mora-Jensen, H.2    Weniger, M.A.3    Gibellini, F.4    Lee, E.5    Daibata, M.6
  • 29
    • 35748936774 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro
    • 17898295 10.1167/iovs.06-1147
    • Poulaki V, Mitsiades CS, Kotoula V, Negri J, McMillin D, Miller JW, et al. The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro. Invest Ophthalmol Vis Sci. 2007;48(10):4706-19.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , Issue.10 , pp. 4706-4719
    • Poulaki, V.1    Mitsiades, C.S.2    Kotoula, V.3    Negri, J.4    McMillin, D.5    Miller, J.W.6
  • 30
    • 68149108384 scopus 로고    scopus 로고
    • PUMA, a potent killer with or without p53
    • Yu J, Zhang L. PUMA, a potent killer with or without p53. Oncogene 2008; S71-83.
    • (2008) Oncogene
    • Yu, J.1    Zhang, L.2
  • 31
    • 47349102144 scopus 로고    scopus 로고
    • Effect of bortezomib on human neuroblastoma: Analysis of molecular mechanisms involved in cytotoxicity
    • 18534018 10.1186/1476-4598-7-50
    • Combaret V, Boyault S, Iacono I, Brejon S, Rousseau R, Puisieux A. Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity. Mol Cancer. 2008;7:50.
    • (2008) Mol Cancer , vol.7 , pp. 50
    • Combaret, V.1    Boyault, S.2    Iacono, I.3    Brejon, S.4    Rousseau, R.5    Puisieux, A.6
  • 32
    • 20144388905 scopus 로고    scopus 로고
    • Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis
    • 15613543 10.1182/blood-2004-10-3984 1:CAS:528:DC%2BD2MXjtlSlsr4%3D
    • Nencioni A, Hua F, Dillon CP, Yokoo R, Scheiermann C, Cardone MH, et al. Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis. Blood. 2005;105(8):3255-62.
    • (2005) Blood , vol.105 , Issue.8 , pp. 3255-3262
    • Nencioni, A.1    Hua, F.2    Dillon, C.P.3    Yokoo, R.4    Scheiermann, C.5    Cardone, M.H.6
  • 33
    • 22144443549 scopus 로고    scopus 로고
    • Upregulation of heat shock protein expression by proteasome inhibition: An antiapoptotic mechanism in the lens
    • 15914627 10.1167/iovs.05-0002
    • Awasthi N, Wagner BJ. Upregulation of heat shock protein expression by proteasome inhibition: an antiapoptotic mechanism in the lens. Invest Ophthalmol Vis Sci. 2005;46(6):2082-91.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.6 , pp. 2082-2091
    • Awasthi, N.1    Wagner, B.J.2
  • 34
    • 0034282104 scopus 로고    scopus 로고
    • Hsp27 negatively regulates cell death by interacting with cytochrome c
    • 10980706 10.1038/35023595 1:CAS:528:DC%2BD3cXmslGks7o%3D
    • Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, et al. Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol. 2000;2(9):645-52.
    • (2000) Nat Cell Biol , vol.2 , Issue.9 , pp. 645-652
    • Bruey, J.M.1    Ducasse, C.2    Bonniaud, P.3    Ravagnan, L.4    Susin, S.A.5    Diaz-Latoud, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.