메뉴 건너뛰기




Volumn 18, Issue 11, 2012, Pages 1534-1540

Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS

(18)  Fox, Robert J a   Thompson, Alan b   Baker, David c   Baneke, Peer d   Brown, Doug e   Browne, Paul d   Chandraratna, Dhia d   Ciccarelli, Olga b   Coetzee, Timothy f   Comi, Giancarlo g   Feinstein, Anthony h   Kapoor, Raj i   Lee, Karen j   Salvetti, Marco k   Sharrock, Kersten l   Toosy, Ahmed b   Zaratin, Paola m   Zuidwijk, Kim n  


Author keywords

multiple sclerosis; neuroprotection; progressive multiple sclerosis; rehabilitation; research agenda

Indexed keywords

ANIMAL; BIOASSAY; CLINICAL TRIAL (TOPIC); COOPERATION; DISEASE MODEL; EXPERIMENTAL THERAPY; HUMAN; INTERDISCIPLINARY COMMUNICATION; INTERNATIONAL COOPERATION; MEDICAL RESEARCH; METHODOLOGY; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; ORGANIZATION; ORGANIZATION AND MANAGEMENT; TREATMENT OUTCOME;

EID: 84868023178     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512458169     Document Type: Review
Times cited : (108)

References (44)
  • 1
    • 0029913882 scopus 로고    scopus 로고
    • Defining the clinical course of multiple sclerosis: Results of an international survey
    • Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey. Neurology. 1996 ; 46: 907-911 (Pubitemid 26134623)
    • (1996) Neurology , vol.46 , Issue.4 , pp. 907-911
    • Lublin, F.D.1    Reingold, S.C.2
  • 2
    • 84862693197 scopus 로고    scopus 로고
    • Primary progressive multiple sclerosis: Part of the MS disease spectrum or separate disease entity?
    • Antel J, Antel S, Caramanos Z, Arnold D, Kuhlmann T. Primary progressive multiple sclerosis: part of the MS disease spectrum or separate disease entity?. Acta Neuropathol (Berl). 2012 ;:
    • (2012) Acta Neuropathol (Berl)
    • Antel, J.1    Antel, S.2    Caramanos, Z.3    Arnold, D.4    Kuhlmann, T.5
  • 3
    • 77953476309 scopus 로고    scopus 로고
    • Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: A randomised, double-blind, placebo-controlled, parallel-group trial
    • Kapoor R, Furby J, Hayton T, et al. Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallel-group trial. Lancet Neurol. 2010 ; 9: 681-688
    • (2010) Lancet Neurol , vol.9 , pp. 681-688
    • Kapoor, R.1    Furby, J.2    Hayton, T.3
  • 4
    • 80054681549 scopus 로고    scopus 로고
    • Experimental in vivo and in vitro models of multiple sclerosis: EAE and beyond
    • Kipp M, van der Star B, Vogel D, et al. Experimental in vivo and in vitro models of multiple sclerosis: EAE and beyond. Multiple Sclerosis and Related Disorders. 2012 ; 1: 15-28
    • (2012) Multiple Sclerosis and Related Disorders , vol.1 , pp. 15-28
    • Kipp, M.1    Van Der Star, B.2    Vogel, D.3
  • 5
    • 79955626592 scopus 로고    scopus 로고
    • Experimental models of multiple sclerosis
    • Pachner AR. Experimental models of multiple sclerosis. Curr Opin Neurol. 2011 ; 24: 291-299
    • (2011) Curr Opin Neurol , vol.24 , pp. 291-299
    • Pachner, A.R.1
  • 7
    • 78549294190 scopus 로고    scopus 로고
    • Chronic progressive multiple sclerosis-pathogenesis of neurodegeneration and therapeutic strategies
    • Fitzner D, Simons M. Chronic progressive multiple sclerosis-pathogenesis of neurodegeneration and therapeutic strategies. Curr Neuropharmacol. 2010 ; 8: 305-315
    • (2010) Curr Neuropharmacol , vol.8 , pp. 305-315
    • Fitzner, D.1    Simons, M.2
  • 9
    • 79952250522 scopus 로고    scopus 로고
    • Models of autoimmune demyelination in the central nervous system: On the way to translational medicine
    • Linker RA, Lee DH. Models of autoimmune demyelination in the central nervous system: on the way to translational medicine. Exp Transl Stroke Med. 2009 ; 1: 5
    • (2009) Exp Transl Stroke Med , vol.1 , pp. 5
    • Linker, R.A.1    Lee, D.H.2
  • 11
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • Sawcer S, Hellenthal G, Pirinen M, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011 ; 476: 214-219
    • (2011) Nature , vol.476 , pp. 214-219
    • Sawcer, S.1    Hellenthal, G.2    Pirinen, M.3
  • 12
    • 77950329947 scopus 로고    scopus 로고
    • Evidence for polygenic susceptibility to multiple sclerosis-the shape of things to come
    • Bush WS, Sawcer SJ, de Jager PL, et al. Evidence for polygenic susceptibility to multiple sclerosis-the shape of things to come. Am J Hum Genet. 2010 ; 86: 621-625
    • (2010) Am J Hum Genet , vol.86 , pp. 621-625
    • Bush, W.S.1    Sawcer, S.J.2    De Jager, P.L.3
  • 13
    • 79952620478 scopus 로고    scopus 로고
    • CytoSolve: A scalable computational method for dynamic integration of multiple molecular pathway models
    • Ayyadurai VA, Dewey CF. CytoSolve: A scalable computational method for dynamic integration of multiple molecular pathway models. Cell Mol Bioeng. 2011 ; 4: 28-45
    • (2011) Cell Mol Bioeng , vol.4 , pp. 28-45
    • Ayyadurai, V.A.1    Dewey, C.F.2
  • 14
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • DOI 10.1126/science.1158140
    • Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P. Drug target identification using side-effect similarity. Science. 2008 ; 321: 263-266 (Pubitemid 351989100)
    • (2008) Science , vol.321 , Issue.5886 , pp. 263-266
    • Campillos, M.1    Kuhn, M.2    Gavin, A.-C.3    Jensen, L.J.4    Bork, P.5
  • 15
    • 70449634957 scopus 로고    scopus 로고
    • Predicting new molecular targets for known drugs
    • Keiser MJ, Setola V, Irwin JJ, et al. Predicting new molecular targets for known drugs. Nature. 2009 ; 462: 175-181
    • (2009) Nature , vol.462 , pp. 175-181
    • Keiser, M.J.1    Setola, V.2    Irwin, J.J.3
  • 16
    • 81255199674 scopus 로고    scopus 로고
    • Nonprofit disease groups earmark grants for drug repositioning
    • Dolgin E. Nonprofit disease groups earmark grants for drug repositioning. Nat Med. 2011 1027 ; 17 :
    • (2011) Nat Med , vol.1027 , pp. 17
    • Dolgin, E.1
  • 17
    • 65249154822 scopus 로고    scopus 로고
    • Magnetic resonance imaging as a potential surrogate for relapses in multiple sclerosis: A meta-analytic approach
    • Sormani MP, Bonzano L, Roccatagliata L, Cutter GR, Mancardi GL, Bruzzi P. Magnetic resonance imaging as a potential surrogate for relapses in multiple sclerosis: a meta-analytic approach. Ann Neurol. 2009 ; 65: 268-275
    • (2009) Ann Neurol , vol.65 , pp. 268-275
    • Sormani, M.P.1    Bonzano, L.2    Roccatagliata, L.3    Cutter, G.R.4    Mancardi, G.L.5    Bruzzi, P.6
  • 18
    • 68349107070 scopus 로고    scopus 로고
    • Imaging outcomes for neuroprotection and repair in multiple sclerosis trials
    • Barkhof F, Calabresi PA, Miller DH, Reingold SC. Imaging outcomes for neuroprotection and repair in multiple sclerosis trials. Nat Rev Neurol. 2009 ; 5: 256-266
    • (2009) Nat Rev Neurol , vol.5 , pp. 256-266
    • Barkhof, F.1    Calabresi, P.A.2    Miller, D.H.3    Reingold, S.C.4
  • 19
    • 78651514193 scopus 로고    scopus 로고
    • Measuring myelin repair and axonal loss with diffusion tensor imaging
    • Fox RJ, Cronin T, Lin J, et al. Measuring myelin repair and axonal loss with diffusion tensor imaging. Am J Neuroradiol. 2011 ; 32: 85-91
    • (2011) Am J Neuroradiol , vol.32 , pp. 85-91
    • Fox, R.J.1    Cronin, T.2    Lin, J.3
  • 20
    • 77950278295 scopus 로고    scopus 로고
    • Brain tissue sodium concentration in multiple sclerosis: A sodium imaging study at 3 tesla
    • Inglese M, Madelin G, Oesingmann N, et al. Brain tissue sodium concentration in multiple sclerosis: a sodium imaging study at 3 tesla. Brain. 2010 ; 133: 847-857
    • (2010) Brain , vol.133 , pp. 847-857
    • Inglese, M.1    Madelin, G.2    Oesingmann, N.3
  • 21
    • 83255187378 scopus 로고    scopus 로고
    • Energy failure in multiple sclerosis and its investigation using MR techniques
    • Paling D, Golay X, Wheeler-Kingshott C, Kapoor R, Miller D. Energy failure in multiple sclerosis and its investigation using MR techniques. J Neurol. 2011 ; 258: 2113-2127
    • (2011) J Neurol , vol.258 , pp. 2113-2127
    • Paling, D.1    Golay, X.2    Wheeler-Kingshott, C.3    Kapoor, R.4    Miller, D.5
  • 22
    • 79953205244 scopus 로고    scopus 로고
    • Towards molecular imaging of multiple sclerosis
    • Owen DR, Piccini P, Matthews PM. Towards molecular imaging of multiple sclerosis. Mult Scler. 2011 ; 17: 262-272
    • (2011) Mult Scler , vol.17 , pp. 262-272
    • Owen, D.R.1    Piccini, P.2    Matthews, P.M.3
  • 23
    • 73349109797 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS
    • Sellebjerg F, Bornsen L, Khademi M, et al. Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS. Neurology. 2009 ; 73: 2003-2010
    • (2009) Neurology , vol.73 , pp. 2003-2010
    • Sellebjerg, F.1    Bornsen, L.2    Khademi, M.3
  • 25
    • 79551478161 scopus 로고    scopus 로고
    • Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab
    • Gunnarsson M, Malmestrom C, Axelsson M, et al. Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab. Ann Neurol. 2011 ; 69: 83-89
    • (2011) Ann Neurol , vol.69 , pp. 83-89
    • Gunnarsson, M.1    Malmestrom, C.2    Axelsson, M.3
  • 26
    • 84929533518 scopus 로고    scopus 로고
    • An adaptive clinical trial design for a sensitive subgroup examined in the multiple sclerosis context
    • Riddell C, Zhao Y, Petkau A. An adaptive clinical trial design for a sensitive subgroup examined in the multiple sclerosis context. Mult Scler. 2011 ; 17: S35
    • (2011) Mult Scler , vol.17 , pp. 35
    • Riddell, C.1    Zhao, Y.2    Petkau, A.3
  • 27
    • 78650993786 scopus 로고    scopus 로고
    • A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis
    • Chataway J, Nicholas R, Todd S, et al. A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis. Mult Scler. 2011 ; 17: 81-88
    • (2011) Mult Scler , vol.17 , pp. 81-88
    • Chataway, J.1    Nicholas, R.2    Todd, S.3
  • 28
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology. 1983 ; 33: 1444-1452 (Pubitemid 14237132)
    • (1983) Neurology , vol.33 , Issue.11 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 29
    • 0025314243 scopus 로고
    • Interrater variability with the expanded disability status scale (EDSS) and functional systems (FS) in a multiple sclerosis clinical trial
    • Noseworthy JH, Vandervoort MK, Wong CJ, Ebers GC. Interrater variability with the expanded disability status scale (EDSS) and functional systems (FS) in a multiple sclerosis clinical trial. Neurology. 1990 ; 40: 971-975 (Pubitemid 20201827)
    • (1990) Neurology , vol.40 , Issue.6 , pp. 971-975
    • Noseworthy, J.H.1    Vandervoort, M.K.2    Wong, C.J.3    Ebers, G.C.4
  • 31
    • 84929526437 scopus 로고    scopus 로고
    • Trials obotIACoC and Sclerosis iM. Disability outcome measures in multiple sclerosis clinical trials: Current status and future prospects
    • Cohen J, Reingold S, Polman C, Wolinsky J. Trials obotIACoC and Sclerosis iM. Disability outcome measures in multiple sclerosis clinical trials: current status and future prospects. Lancet Neurol. 2012 ;:
    • (2012) Lancet Neurol
    • Cohen, J.1    Reingold, S.2    Polman, C.3    Wolinsky, J.4
  • 32
    • 77956291305 scopus 로고    scopus 로고
    • Quality of life in multiple sclerosis: Determinants, measurement, and use in clinical practice
    • Miller DM, Allen R. Quality of life in multiple sclerosis: determinants, measurement, and use in clinical practice. Current Neurology & Neuroscience Reports. 2010 ; 10: 397-406
    • (2010) Current Neurology & Neuroscience Reports , vol.10 , pp. 397-406
    • Miller, D.M.1    Allen, R.2
  • 33
    • 33746261692 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Silver Spring, MD: Office of Communications, Division of Drug Information, Food and Drug Administration
    • U.S. Food and Drug Administration. Guidance for industry patient-reported outcome measures: Use in medical product development to support labeling claims. http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/ Guidances/default.htm. Silver Spring, MD: Office of Communications, Division of Drug Information, Food and Drug Administration, 2009.
    • (2009) Guidance for Industry Patient-reported Outcome Measures: Use in Medical Product Development to Support Labeling Claims
  • 34
    • 78349289202 scopus 로고    scopus 로고
    • Pharmacological management of symptoms in multiple sclerosis: Current approaches and future directions
    • Thompson AJ, Toosy AT, Ciccarelli O. Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions. Lancet Neurol. 2010 ; 9: 1182-1199
    • (2010) Lancet Neurol , vol.9 , pp. 1182-1199
    • Thompson, A.J.1    Toosy, A.T.2    Ciccarelli, O.3
  • 35
    • 0242654882 scopus 로고    scopus 로고
    • Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): Multicentre randomised placebo-controlled trial
    • DOI 10.1016/S0140-6736(03)14738-1
    • Zajicek J, Fox P, Sanders H, et al. Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial. Lancet. 2003 ; 362: 1517-1526 (Pubitemid 37410189)
    • (2003) Lancet , vol.362 , Issue.9395 , pp. 1517-1526
    • Zajicek, J.1    Fox, P.2    Sanders, H.3    Wright, D.4    Vickery, J.5    Nunn, A.6    Thompson, A.7
  • 36
    • 60649090430 scopus 로고    scopus 로고
    • Sustained-release oral fampridine in multiple sclerosis: A randomised, double-blind, controlled trial
    • Goodman AD, Brown TR, Krupp LB, et al. Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial. Lancet. 2009 ; 373: 732-738
    • (2009) Lancet , vol.373 , pp. 732-738
    • Goodman, A.D.1    Brown, T.R.2    Krupp, L.B.3
  • 38
    • 0035214749 scopus 로고    scopus 로고
    • Comparative outcomes for individual cognitive-behavior therapy, supportive-expressive group psychotherapy, and sertraline for the treatment of depression in multiple sclerosis
    • DOI 10.1037//0022-006X.69.6.942
    • Mohr DC, Boudewyn AC, Goodkin DE, Bostrom A, Epstein L. Comparative outcomes for individual cognitive-behavior therapy, supportive-expressive group psychotherapy, and sertraline for the treatment of depression in multiple sclerosis. J Consult Clin Psychol. 2001 ; 69: 942-949 (Pubitemid 33140495)
    • (2001) Journal of Consulting and Clinical Psychology , vol.69 , Issue.6 , pp. 942-949
    • Mohr, D.C.1    Boudewyn, A.C.2    Goodkin, D.E.3    Bostrom, A.4    Epstein, L.5
  • 39
    • 33846557503 scopus 로고    scopus 로고
    • Anxiety disorders and their clinical correlates in multiple sclerosis patients
    • DOI 10.1177/1352458506071161
    • Korostil M, Feinstein A. Anxiety disorders and their clinical correlates in multiple sclerosis patients. Mult Scler. 2007 ; 13: 67-72 (Pubitemid 46152763)
    • (2007) Multiple Sclerosis , vol.13 , Issue.1 , pp. 67-72
    • Korostil, M.1    Feinstein, A.2
  • 40
    • 33645456999 scopus 로고    scopus 로고
    • Functional brain reorganization in multiple sclerosis: Evidence from fMRI studies
    • Pantano P, Mainero C, Caramia F. Functional brain reorganization in multiple sclerosis: evidence from fMRI studies. J Neuroimaging. 2006 ; 16: 104-114
    • (2006) J Neuroimaging , vol.16 , pp. 104-114
    • Pantano, P.1    Mainero, C.2    Caramia, F.3
  • 41
    • 24944571009 scopus 로고    scopus 로고
    • Cortical adaptation in patients with MS: A cross-sectional functional MRI study of disease phenotypes
    • DOI 10.1016/S1474-4422(05)70171-X, PII S147444220570171X
    • Rocca MA, Colombo B, Falini A, et al. Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes. Lancet Neurol. 2005 ; 4: 618-26 (Pubitemid 41317296)
    • (2005) Lancet Neurology , vol.4 , Issue.10 , pp. 618-626
    • Rocca, M.A.1    Colombo, B.2    Falini, A.3    Ghezzi, A.4    Martinelli, V.5    Scotti, G.6    Comi, G.7    Filippi, M.8
  • 43
    • 34248524323 scopus 로고    scopus 로고
    • Relation between functional brain imaging, cognitive impairment and cognitive rehabilitation in patients with multiple sclerosis
    • Penner I, Opwis K, Kappos L. Relation between functional brain imaging, cognitive impairment and cognitive rehabilitation in patients with multiple sclerosis. J Neurol. 2007 ; 254 2: 1153-1157
    • (2007) J Neurol , vol.2542 , pp. 1153-1157
    • Penner, I.1    Opwis, K.2    Kappos, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.