-
1
-
-
33745684404
-
Melanoma
-
PMID:16822996; http://dx.doi.org/10.1056/NEJMra052166
-
Miller AJ, Mihm MC Jr. Melanoma. N Engl J Med 2006;355:51-65; PMID:16822996; http://dx.doi.org/10.1056/NEJMra052166.
-
(2006)
N Engl J Med
, vol.355
, pp. 51-65
-
-
Miller, A.J.1
Mihm Jr., M.C.2
-
3
-
-
79955768010
-
Annual report to the nation on the status of cancer, 1975-2007, featuring tumors of the brain and other nervous system
-
PMID:21454908; http://dx.doi.org/10.1093/jnci/djr077
-
Kohler BA, Ward E, McCarthy BJ, Schymura MJ, Ries LAG, Eheman C, et al. Annual report to the nation on the status of cancer, 1975-2007, featuring tumors of the brain and other nervous system. J Natl Cancer Inst 2011;103:714-36; PMID:21454908; http://dx.doi.org/10.1093/jnci/djr077.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 714-736
-
-
Kohler, B.A.1
Ward, E.2
McCarthy, B.J.3
Schymura, M.J.4
Ries, L.A.G.5
Eheman, C.6
-
4
-
-
77956513286
-
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
-
PMID:20823850; http://dx.doi.org/10.1038/nature09454
-
Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature 2010;467:596-9; PMID:20823850; http://dx.doi.org/10.1038/nature09454.
-
(2010)
Nature
, vol.467
, pp. 596-599
-
-
Bollag, G.1
Hirth, P.2
Tsai, J.3
Zhang, J.4
Ibrahim, P.N.5
Cho, H.6
-
5
-
-
77957968556
-
PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas
-
PMID:20973932; http://dx.doi.org/10.1111/j.1755-148X.2010.00763.x
-
Lee JT, Li L, Brafford PA, van den Eijnden M, Halloran MB, Sproesser K, et al. PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Pigment Cell Melanoma Res 2010;23:820-7; PMID:20973932; http://dx.doi.org/10.1111/j.1755-148X.2010.00763.x.
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 820-827
-
-
Lee, J.T.1
Li, L.2
Brafford, P.A.3
Van Den Eijnden, M.4
Halloran, M.B.5
Sproesser, K.6
-
6
-
-
42949149240
-
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
-
DOI 10.1073/pnas.0711741105
-
Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, et al. Discovery of a selective inhibitor of onco-genic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci USA 2008;105:3041-6; PMID:18287029; http://dx.doi.org/10.1073/pn a s. 0 711741105. (Pubitemid 351723664)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.8
, pp. 3041-3046
-
-
Tsai, J.1
Lee, J.T.2
Wang, W.3
Zhang, J.4
Cho, H.5
Mamo, S.6
Bremer, R.7
Gillette, S.8
Kong, J.9
Haass, N.K.10
Sproesser, K.11
Li, L.12
Smalley, K.S.M.13
Fong, D.14
Zhu, Y.-L.15
Marimuthu, A.16
Nguyen, H.17
Lam, B.18
Liu, J.19
Cheung, I.20
Rice, J.21
Suzuki, Y.22
Luu, C.23
Settachatgul, C.24
Shellooe, R.25
Cantwell, J.26
Kim, S.-H.27
Schlessinger, J.28
Zhang, K.Y.J.29
West, B.L.30
Powell, B.31
Habets, G.32
Zhang, C.33
Ibrahim, P.N.34
Hirth, P.35
Artis, D.R.36
Herlyn, M.37
Bollag, G.38
more..
-
7
-
-
77954376912
-
RG7204(PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models
-
PMID:20551065; http://dx.doi.org/10.1158/0008-5472. CAN-10-0646
-
Yang H, Higgins B, Kolinsky K, Packman K, Go Z, Iyer R, et al. RG7204(PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models. Cancer Res 2010;70:5518-27; PMID:20551065; http://dx.doi.org/10.1158/0008-5472. CAN-10-0646.
-
(2010)
Cancer Res
, vol.70
, pp. 5518-5527
-
-
Yang, H.1
Higgins, B.2
Kolinsky, K.3
Packman, K.4
Go, Z.5
Iyer, R.6
-
8
-
-
57549098807
-
The catalogue of somatic mutations in cancer (COSMIC)
-
Jonathan L Haines et Al, Chapter 10:Unit 10.1-Unit. 1
-
Forbes SA, Bhamra G, Bamford S, Dawson E, Kok C, Clements J, et al. The Catalogue of Somatic Mutations in Cancer (COSMIC). Current Protocols in Human Genetics/Editorial Board, Jonathan L Haines [et Al] 2008; Chapter 10:Unit 10.1-Unit. 1.
-
(2008)
Current Protocols in Human Genetics/Editorial Board
-
-
Forbes, S.A.1
Bhamra, G.2
Bamford, S.3
Dawson, E.4
Kok, C.5
Clements, J.6
-
9
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res 2010;39:945-50.
-
(2010)
Nucleic Acids Res
, vol.39
, pp. 945-950
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
Cole, C.4
Kok, C.Y.5
Beare, D.6
-
10
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
BRIM-3 Study Group, PMID:21639808; http://dx.doi.org/10.1056/ NEJMoa1103782
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al.; BRIM-3 Study Group. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011;364:2507-16; PMID:21639808; http://dx.doi.org/10.1056/NEJMoa1103782.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
11
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
PMID:20818844; http://dx.doi.org/10.1056/NEJMoa1002011
-
Flaherty K T, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010;363:809-19; PMID:20818844; http://dx.doi.org/10.1056/NEJMoa1002011.
-
(2010)
N Engl J Med
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
Ribas, A.4
McArthur, G.A.5
Sosman, J.A.6
-
12
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
PMID:22356324; http://dx.doi.org/10.1056/NEJMoa1112302
-
Sosman JA, Kim KB, Schuchter L, Gonzalez R, Pavlick AC, Weber JS, et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med 2012;366:707-14; PMID:22356324; http://dx.doi.org/10.1056/NEJMoa1112302.
-
(2012)
N Engl J Med
, vol.366
, pp. 707-714
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
Gonzalez, R.4
Pavlick, A.C.5
Weber, J.S.6
-
13
-
-
67449150167
-
A Wnt survival guide: From flies to human disease
-
PMID:19177135; http://dx.doi.org/10.1038/jid.2008.445
-
Chien AJ, Conrad WH, Moon RT. A Wnt survival guide: from flies to human disease. J Invest Dermatol 2009;129:1614-27; PMID:19177135; http://dx.doi.org/ 10.1038/jid.2008.445.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1614-1627
-
-
Chien, A.J.1
Conrad, W.H.2
Moon, R.T.3
-
14
-
-
0032569852
-
Control of neural crest cell fate by the Wnt signalling pathway
-
DOI 10.1038/24620
-
Dorsky RI, Moon RT, Raible DW. Control of neural crest cell fate by the Wnt signalling pathway. Nature 1998;396:370-3; PMID:9845073; http://dx.doi.org/10.1038/24620. (Pubitemid 28557397)
-
(1998)
Nature
, vol.396
, Issue.6709
, pp. 370-372
-
-
Dorsky, R.I.1
Moon, R.T.2
Raible, D.W.3
-
15
-
-
0033860456
-
Environmental signals and cell fate specification in premigratory neural crest
-
DOI 10.1002/1521-1878(200008)22:8<708::AID-BIES4>3.0.CO;2-N
-
Dorsky RI, Moon RT, Raible DW. Environmental signals and cell fate specification in premigra-tory neural crest. Bioessays 2000;22:708-16; PMID:10918301; http://dx.doi.org/10.1002/1521-1878 (200008) 22:8<708::AID- BIES4>3.0. CO;2-N. (Pubitemid 30613302)
-
(2000)
BioEssays
, vol.22
, Issue.8
, pp. 708-716
-
-
Dorsky, R.I.1
Moon, R.T.2
Raible, D.W.3
-
16
-
-
0034650485
-
Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway
-
Dorsky RI, Raible DW, Moon RT. Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway. Genes Dev 2000;14:158-62; PMID:10652270. (Pubitemid 30070981)
-
(2000)
Genes and Development
, vol.14
, Issue.2
, pp. 158-162
-
-
Dorsky, R.I.1
Raible, D.W.2
Moon, R.T.3
-
17
-
-
0038578680
-
β-catenin in the melanocyte lineage
-
DOI 10.1034/j.1600-0749.2003.00050.x
-
Larue L, Kumasaka M, Goding CR. Beta-catenin in the melanocyte lineage. Pigment Cell Res 2003;16:312-7; PMID:12753406; http://dx.doi.org/10.1034/j.1600- 0749.2003.00050.x. (Pubitemid 36597073)
-
(2003)
Pigment Cell Research
, vol.16
, Issue.3
, pp. 312-317
-
-
Larue, L.1
Kumasaka, M.2
Goding, C.R.3
-
18
-
-
3342979536
-
The transcription network regulating melanocyte development and melanoma
-
DOI 10.1111/j.1600-0749.2004.00164.x
-
Vance K W, Goding CR. The transcription network regulating melanocyte development and melanoma. Pigment Cell Res 2004;17:318-25; PMID:15250933;http:// dx.doi.org/10.1111/j.1600-0749.2004.00164.x. (Pubitemid 38993061)
-
(2004)
Pigment Cell Research
, vol.17
, Issue.4
, pp. 318-325
-
-
Vance, K.W.1
Goding, C.R.2
-
19
-
-
29344459785
-
Importance of P-cadherin, β-catenin, and Wnt5a/Frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma
-
DOI 10.1158/1078-0432.CCR-05-0011
-
Bachmann IM, Straume O, Puntervoll HE, Kalvenes MB, Akslen LA. Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clin Cancer Res 2005;11:8606-14; PMID:16361544;http://dx.doi.org/10.1158/1078-0432. CCR-05-0011. (Pubitemid 43005907)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.24
, pp. 8606-8614
-
-
Bachmann, I.M.1
Straume, O.2
Puntervoll, H.E.3
Kalvenes, M.B.4
Akslen, L.A.5
-
20
-
-
0034799321
-
Loss of β-catenin expression associated with disease progression in malignant melanoma
-
DOI 10.1046/j.1365-2133.2001.04336.x
-
Kageshita T, Hamby CV, Ishihara T, Matsumoto K, Saida T, Ono T. Loss of beta-catenin expression associated with disease progression in malignant melanoma. Br J Dermatol 2001;145:210-6; PMID:11531781; http://dx.doi.org/10. 1046/j.1365-2133.2001.04336.x. (Pubitemid 32955344)
-
(2001)
British Journal of Dermatology
, vol.145
, Issue.2
, pp. 210-216
-
-
Kageshita, T.1
Hamby, C.V.2
Ishihara, T.3
Matsumoto, K.4
Saida, T.5
Ono, T.6
-
21
-
-
0042835743
-
Reduced β-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma
-
Maelandsmo GM, Holm R, Nesland JM, Fodstad O, Flørenes VA. Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma. Clin Cancer Res 2003;9:3383-8; PMID:12960126. (Pubitemid 37082733)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.9
, pp. 3383-3388
-
-
Maelandsmo, G.M.1
Holm, R.2
Nesland, J.M.3
Fodstad, O.4
Florenes, V.A.5
-
22
-
-
59049101982
-
Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
-
PMID:19144919; http://dx.doi.org/10.1073/pnas.0811902106
-
Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, et al. Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci USA 2009;106:1193-8; PMID:19144919; http://dx.doi.org/10.1073/pnas. 0811902106.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1193-1198
-
-
Chien, A.J.1
Moore, E.C.2
Lonsdorf, A.S.3
Kulikauskas, R.M.4
Rothberg, B.G.5
Berger, A.J.6
-
23
-
-
84862001719
-
A seven-marker signature and clinical outcome in malignant melanoma: A large-scale tissue-microarray study with two independent patient cohorts
-
PMID:22685558; http://dx.doi.org/10.1371/jour-nal.pone.0038222
-
Meyer S, Fuchs TJ, Bosserhoff AK, Hofstädter F, Pauer A, Roth V, et al. A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts. PLoS ONE 2012;7:e38222; PMID:22685558; http://dx.doi.org/10.1371/jour-nal.pone. 0038222.
-
(2012)
PLoS ONE
, vol.7
-
-
Meyer, S.1
Fuchs, T.J.2
Bosserhoff, A.K.3
Hofstädter, F.4
Pauer, A.5
Roth, V.6
-
24
-
-
84855696067
-
Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma
-
PMID:22234612; http://dx.doi.org/10.1126/scisig-nal.2002274
-
Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, et al. Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Sci Signal 2012;5:ra3; PMID:22234612; http://dx.doi.org/10.1126/scisig-nal.2002274.
-
(2012)
Sci Signal
, vol.5
-
-
Biechele, T.L.1
Kulikauskas, R.M.2
Toroni, R.A.3
Lucero, O.M.4
Swift, R.D.5
James, R.G.6
-
25
-
-
4243067196
-
The roles of APC and axin derived from experimental and theoretical analysis of the Wnt pathway
-
DOI 10.1371/journal.pbio.0000010
-
Lee E, Salic A, Krüger R, Heinrich R, Kirschner M W. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol 2003;1:E10; PMID:14551908; http://dx.doi.org/10.1371/journal. pbio.0000010. (Pubitemid 39112198)
-
(2003)
PLoS Biology
, vol.1
, Issue.1
-
-
Lee, E.1
Salic, A.2
Kruger, R.3
Heinrich, R.4
Kirschner, M.W.5
-
26
-
-
0033714885
-
Control of beta-catenin stability: Reconstitution of the cytoplas-mic steps of the wnt pathway in Xenopus egg extracts
-
PMID:10882137; http://dx.doi.org/10.1016/S1097-2765 00 80446-3
-
Salic A, Lee E, Mayer L, Kirschner MW. Control of beta-catenin stability: reconstitution of the cytoplas-mic steps of the wnt pathway in Xenopus egg extracts. Mol Cell 2000;5:523-32; PMID:10882137; http://dx.doi.org/10.1016/ S1097-2765 (00) 80446-3.
-
(2000)
Mol Cell
, vol.5
, pp. 523-532
-
-
Salic, A.1
Lee, E.2
Mayer, L.3
Kirschner, M.W.4
-
27
-
-
0033565533
-
Wnt-induced dephosphorylation of Axin releases β-catenin from the Axin complex
-
Willert K, Shibamoto S, Nusse R. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev 1999;13:1768-73; PMID:10421629; http://dx.doi.org/10.1101/gad.13.14.1768. (Pubitemid 29353044)
-
(1999)
Genes and Development
, vol.13
, Issue.14
, pp. 1768-1773
-
-
Willert, K.1
Shibamoto, S.2
Nusse, R.3
-
28
-
-
0033574527
-
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability
-
DOI 10.1074/jbc.274.16.10681
-
Yamamoto H, Kishida S, Kishida M, Ikeda S, Takada S, Kikuchi A. Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability. J Biol Chem 1999;274:10681-4; PMID:10196136; http://dx.doi.org/10.1074/jbc.274.16.10681. (Pubitemid 29191041)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.16
, pp. 10681-10684
-
-
Yamamoto, H.1
Kishida, S.2
Kishida, M.3
Ikeda, S.4
Takada, S.5
Kikuchi, A.6
-
29
-
-
79956115033
-
Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling
-
PMID:21242974; http://dx.doi.org/10.1038/onc.2010.610
-
Cha B, Kim W, Kim YK, Hwang BN, Park SY, Yoon J W, et al. Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling. Oncogene 2011;30:2379-89; PMID:21242974; http://dx.doi.org/10.1038/onc.2010.610.
-
(2011)
Oncogene
, vol.30
, pp. 2379-2389
-
-
Cha, B.1
Kim, W.2
Kim, Y.K.3
Hwang, B.N.4
Park, S.Y.5
Yoon, J.W.6
-
30
-
-
63649083462
-
Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma
-
PMID:19362540; http://dx.doi.org/10.1016/j.molcel.2009.03.007
-
Old WM, Shabb JB, Houel S, Wang H, Couts KL, Yen CY, et al. Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. Mol Cell 2009;34:115-31; PMID:19362540; http://dx.doi.org/10.1016/j.molcel. 2009.03.007.
-
(2009)
Mol Cell
, vol.34
, pp. 115-131
-
-
Old, W.M.1
Shabb, J.B.2
Houel, S.3
Wang, H.4
Couts, K.L.5
Yen, C.Y.6
-
31
-
-
55549111212
-
SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability
-
PMID:18632848; http://dx.doi.org/10.1096/fj.08-113910
-
Kim MJ, Chia I V, Costantini F. SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability. FASEB J 2008;22:3785-94; PMID:18632848; http://dx.doi.org/10.1096/fj.08-113910.
-
(2008)
FASEB J
, vol.22
, pp. 3785-3794
-
-
Kim, M.J.1
Chia, I.V.2
Costantini, F.3
-
32
-
-
79960727271
-
Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling
-
PMID:21799911; http://dx.doi.org/10.1371/journal.pone.0022595
-
Callow MG, Tran H, Phu L, Lau T, Lee J, Sandoval WN, et al. Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling. PLoS ONE 2011;6:e22595; PMID:21799911; http://dx.doi.org/10.1371/journal.pone.0022595.
-
(2011)
PLoS ONE
, vol.6
-
-
Callow, M.G.1
Tran, H.2
Phu, L.3
Lau, T.4
Lee, J.5
Sandoval, W.N.6
-
33
-
-
79955617241
-
RNF146 is a poly (ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling
-
PMID:21478859; http://dx.doi.org/10.1038/ncb2222
-
Zhang Y, Liu S, Mickanin C, Feng Y, Charlat O, Michaud GA, et al. RNF146 is a poly (ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling. Nat Cell Biol 2011;13:623-9; PMID:21478859; http://dx.doi.org/ 10.1038/ncb2222.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 623-629
-
-
Zhang, Y.1
Liu, S.2
Mickanin, C.3
Feng, Y.4
Charlat, O.5
Michaud, G.A.6
-
34
-
-
79956128376
-
The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling
-
PMID:21383061; http://dx.doi.org/10.1128/MCB.01094-10
-
Lui TTH, Lacroix C, Ahmed SM, Goldenberg SJ, Leach CA, Daulat AM, et al. The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling. Mol Cell Biol 2011;31:2053-65; PMID:21383061; http://dx.doi.org/10.1128/MCB.01094-10.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2053-2065
-
-
Lui, T.T.H.1
Lacroix, C.2
Ahmed, S.M.3
Goldenberg, S.J.4
Leach, C.A.5
Daulat, A.M.6
-
35
-
-
36249026528
-
INK4a expression and cooperates with N-Ras in melanoma development
-
DOI 10.1101/gad.450107
-
Delmas V, Beermann F, Martinozzi S, Carreira S, Ackermann J, Kumasaka M, et al. Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev 2007;21:2923-35; PMID:18006687; http://dx.doi.org/10.1101/gad.450107. (Pubitemid 350133440)
-
(2007)
Genes and Development
, vol.21
, Issue.22
, pp. 2923-2935
-
-
Delmas, V.1
Beermann, F.2
Martinozzi, S.3
Carreira, S.4
Ackermann, J.5
Kumasaka, M.6
Denat, L.7
Goodall, J.8
Luciani, F.9
Viros, A.10
Demirkan, N.11
Bastian, B.C.12
Goding, C.R.13
Larue, L.14
-
36
-
-
83455171909
-
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas
-
PMID:22172720; http://dx.doi.org/10.1016/j.ccr.2011.10.030
-
Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Gould Rothberg BE, et al. β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell 2011;20:741-54; PMID:22172720; http://dx.doi.org/10.1016/j.ccr.2011.10.030.
-
(2011)
Cancer Cell
, vol.20
, pp. 741-754
-
-
Damsky, W.E.1
Curley, D.P.2
Santhanakrishnan, M.3
Rosenbaum, L.E.4
Platt, J.T.5
Gould Rothberg, B.E.6
-
37
-
-
0035877115
-
Cytoplasmic and nuclear accumulation of β-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma
-
DOI 10.1002/ijc.1270
-
Omholt K, Platz A, Ringborg U, Hansson J. Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma. Int J Cancer 2001;92:839-42; PMID:11351304; http://dx.doi.org/10.1002/ijc.1270. (Pubitemid 32467373)
-
(2001)
International Journal of Cancer
, vol.92
, Issue.6
, pp. 839-842
-
-
Omholt, K.1
Platz, A.2
Ringborg, U.3
Hansson, J.4
-
38
-
-
0036256209
-
Mutations in exon 3 of the β-catenin gene are rare in melanoma cell lines
-
DOI 10.1097/00008390-200204000-00013
-
Pollock PM, Hayward N. Mutations in exon 3 of the beta-catenin gene are rare in melanoma cell lines. Melanoma Res 2002;12:183-6; PMID:11930117; http://dx.doi.org/10.1097/00008390-200204000-00013. (Pubitemid 34478461)
-
(2002)
Melanoma Research
, vol.12
, Issue.2
, pp. 183-186
-
-
Pollock, P.M.1
Hayward, N.2
-
39
-
-
0032937232
-
Frequent nuclear/cytoplasmic localization of β-catenin without exon 3 mutations in malignant melanoma
-
Rimm DL, Caca K, Hu G, Harrison FB, Fearon ER. Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. Am J Pathol 1999;154:325-9; PMID:10027390; http://dx.doi.org/10.1016/S0002-9440 (10) 65278-9. (Pubitemid 29094082)
-
(1999)
American Journal of Pathology
, vol.154
, Issue.2
, pp. 325-329
-
-
Rimm, D.L.1
Caca, K.2
Hu, G.3
Harrison, F.B.4
Fearon, E.R.5
-
40
-
-
84862907872
-
The BRAF (V600E) causes widespread alterations in gene methyla-tion in the genome of melanoma cells
-
PMID:22189819; http://dx.doi.org/10.4161/cc.11.2.18707
-
Hou P, Liu D, Dong J, Xing M. The BRAF (V600E) causes widespread alterations in gene methyla-tion in the genome of melanoma cells. Cell Cycle 2012;11:286-95; PMID:22189819; http://dx.doi.org/10.4161/cc.11.2.18707.
-
(2012)
Cell Cycle
, vol.11
, pp. 286-295
-
-
Hou, P.1
Liu, D.2
Dong, J.3
Xing, M.4
-
41
-
-
84861894470
-
The tumor suppressor HINT1 regulates MITF and β-catenin transcriptional activity in melanoma cells
-
PMID:22647378; http://dx.doi.org/10.4161/cc.20765
-
Genovese G, Ghosh P, Li H, Rettino A, Sioletic S, Cittadini A, et al. The tumor suppressor HINT1 regulates MITF and β-catenin transcriptional activity in melanoma cells. Cell Cycle 2012;11:2206-15; PMID:22647378; http://dx.doi.org/10.4161/cc.20765.
-
(2012)
Cell Cycle
, vol.11
, pp. 2206-2215
-
-
Genovese, G.1
Ghosh, P.2
Li, H.3
Rettino, A.4
Sioletic, S.5
Cittadini, A.6
-
42
-
-
84857956747
-
NUAK2: An emerging acral melanoma oncogene
-
PMID:21911917
-
Namiki T, Coelho SG, Hearing VJ. NUAK2: an emerging acral melanoma oncogene. Oncotarget 2011;2:695-704; PMID:21911917.
-
(2011)
Oncotarget
, vol.2
, pp. 695-704
-
-
Namiki, T.1
Coelho, S.G.2
Hearing, V.J.3
-
43
-
-
58649110598
-
Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
-
PMID:19187764; http://dx.doi.org/10.1016/j. molcel.2008.12.026
-
Zheng B, Jeong JH, Asara JM, Yuan YY, Granter SR, Chin L, et al. Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol Cell 2009;33:237-47; PMID:19187764; http://dx.doi.org/10.1016/j. molcel.2008.12.026.
-
(2009)
Mol Cell
, vol.33
, pp. 237-247
-
-
Zheng, B.1
Jeong, J.H.2
Asara, J.M.3
Yuan, Y.Y.4
Granter, S.R.5
Chin, L.6
-
44
-
-
80053307869
-
Potential therapeutic strategies to overcome acquired resistance to BRAF or MEK inhibitors in BRAF mutant cancers
-
PMID:21505228
-
Corcoran RB, Settleman J, Engelman JA. Potential therapeutic strategies to overcome acquired resistance to BRAF or MEK inhibitors in BRAF mutant cancers. Oncotarget 2011;2:336-46; PMID:21505228.
-
(2011)
Oncotarget
, vol.2
, pp. 336-346
-
-
Corcoran, R.B.1
Settleman, J.2
Engelman, J.A.3
|