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Volumn 61, Issue 11, 2012, Pages 2657-2658

Understanding the elusive mechanism of action of TCF7L2 in metabolism

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; MESSENGER RNA; TRANSCRIPTION FACTOR 7 LIKE 2;

EID: 84868014745     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0891     Document Type: Note
Times cited : (8)

References (11)
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  • 2
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • Sladek R, Rocheleau G, Rung J, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007;445: 881-885
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  • 3
    • 34447340935 scopus 로고    scopus 로고
    • TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: A global meta-analysis
    • Cauchi S, El Achhab Y, Choquet H, et al. TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med (Berl) 2007;85:777-782
    • (2007) J Mol Med (Berl) , vol.85 , pp. 777-782
    • Cauchi, S.1    El Achhab, Y.2    Choquet, H.3
  • 4
    • 84868035640 scopus 로고    scopus 로고
    • Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism
    • Kaminska D, Kuulasmaa T, Venesmaa S, et al. Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism. Diabetes 2012;61:2807-2813
    • (2012) Diabetes , vol.61 , pp. 2807-2813
    • Kaminska, D.1    Kuulasmaa, T.2    Venesmaa, S.3
  • 5
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    • Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humans
    • Mondal AK, Das SK, Baldini G, et al. Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humans. J Clin Endocrinol Metab 2010;95:1450-1457
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    • Mondal, A.K.1    Das, S.K.2    Baldini, G.3
  • 6
    • 77949268930 scopus 로고    scopus 로고
    • Evidence for neuroendocrine function of a unique splicing form of TCF7L2 in human brain, islets and gut
    • Prokunina-Olsson L, Hall JL. Evidence for neuroendocrine function of a unique splicing form of TCF7L2 in human brain, islets and gut. Diabetologia 2010;53:712-716
    • (2010) Diabetologia , vol.53 , pp. 712-716
    • Prokunina-Olsson, L.1    Hall, J.L.2
  • 7
    • 33746075560 scopus 로고    scopus 로고
    • TCF7L2 polymorphisms and progression to diabetes in the diabetes prevention program
    • Diabetes Prevention Program Research Group
    • Florez JC, Jablonski KA, Bayley N, et al, Diabetes Prevention Program Research Group. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 2006;355:241-250
    • (2006) N Engl J Med , vol.355 , pp. 241-250
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  • 8
    • 34547702501 scopus 로고    scopus 로고
    • Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
    • Lyssenko V, Lupi R, Marchetti P, et al. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest 2007;117:2155-2163
    • (2007) J Clin Invest , vol.117 , pp. 2155-2163
    • Lyssenko, V.1    Lupi, R.2    Marchetti, P.3
  • 9
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    • Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo
    • Zhao J, Schug J, Li M, Kaestner KH, Grant SF. Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo. Diabetologia 2010;53:2340-2346
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    • The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer
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    • The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced wnt signaling
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.