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Volumn 11, Issue 20, 2012, Pages 3828-3836

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation

Author keywords

EZH2; MyoD; Myogenesis; PRC complex; Rhabdomyosarcoma

Indexed keywords


EID: 84868014011     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.22025     Document Type: Article
Times cited : (47)

References (48)
  • 1
    • 0033588883 scopus 로고    scopus 로고
    • Rhabdomyosarcoma - Working out the pathways
    • DOI 10.1038/sj.onc.1203038
    • Merlino G, Helman LJ. Rhabdomyosarcoma-working out the pathways. Oncogene 1999;18:5340-8; PMID:10498887; http://dx.doi.org/10.1038/sj.onc.1203038. (Pubitemid 29462370)
    • (1999) Oncogene , vol.18 , Issue.38 , pp. 5340-5348
    • Merlino, G.1    Helman, L.J.2
  • 3
    • 0037634085 scopus 로고    scopus 로고
    • Myogenin and MyoD1 expression in paediatric rhabdomyosarcomas
    • Sebire NJ, Malone M. Myogenin and MyoD1 expression in paediatric rhabdomyosarcomas. J Clin Pathol 2003;56:412-6; PMID:12783965; http://dx.doi.org/10.1136/jcp. 56.6.412. (Pubitemid 36724206)
    • (2003) Journal of Clinical Pathology , vol.56 , Issue.6 , pp. 412-416
    • Sebire, N.J.1    Malone, M.2
  • 5
    • 0033804899 scopus 로고    scopus 로고
    • Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications
    • PMID:11025438; http://dx.doi.org/10.1002/1097-4652 200011 185:2<155::AID-JCP1>3.0. CO;2-Z
    • Puri PL, Sartorelli V. Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications. J Cell Physiol 2000;185:155-73; PMID:11025438; http://dx.doi.org/10.1002/1097-4652 (200011) 185:2<155::AID-JCP1>3.0. CO;2-Z.
    • (2000) J Cell Physiol , vol.185 , pp. 155-173
    • Puri, P.L.1    Sartorelli, V.2
  • 6
    • 0036204443 scopus 로고    scopus 로고
    • Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression
    • DOI 10.1016/S1097-2765(02)00481-1
    • Bergstrom DA, Penn BH, Strand A, Perry RL, Rudnicki MA, Tapscott SJ. Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression. Mol Cell 2002;9:587-600; PMID:11931766; http://dx.doi.org/10.1016/S1097-2765 (02) 00481-1. (Pubitemid 34273789)
    • (2002) Molecular Cell , vol.9 , Issue.3 , pp. 587-600
    • Bergstrom, D.A.1    Penn, B.H.2    Strand, A.3    Perry, R.L.S.4    Rudnicki, M.A.5    Tapscott, S.J.6
  • 7
    • 3042763342 scopus 로고    scopus 로고
    • P38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
    • DOI 10.1038/ng1378
    • Simone C, Forcales SV, Hill DA, Imbalzano AN, Latella L, Puri PL. p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat Genet 2004;36:738-43; PMID:15208625; http://dx.doi.org/10.1038/ng1378. (Pubitemid 38886636)
    • (2004) Nature Genetics , vol.36 , Issue.7 , pp. 738-743
    • Simone, C.1    Forcales, S.V.2    Hill, D.A.3    Imbalzano, A.N.4    Latella, L.5    Puri, P.L.6
  • 8
    • 31944443463 scopus 로고    scopus 로고
    • MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions
    • DOI 10.1002/jcp.20523
    • Giacinti C, Bagella L, Puri PL, Giordano A, Simone C. MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions. J Cell Physiol 2006;206:807-13; PMID:16245309; http://dx.doi.org/10.1002/jcp. 20523. (Pubitemid 43191056)
    • (2006) Journal of Cellular Physiology , vol.206 , Issue.3 , pp. 807-813
    • Giacinti, C.1    Bagella, L.2    Puri, P.L.3    Giordano, A.4    Simone, C.5
  • 10
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. The fundamental role of epigen-etic events in cancer. Nat Rev Genet 2002;3:415-28; PMID:12042769. (Pubitemid 34587077)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 11
    • 33845417885 scopus 로고    scopus 로고
    • The cancer epigenome - Components and functional correlates
    • DOI 10.1101/gad.1464906
    • Ting AH, McGarvey KM, Baylin SB. The cancer epig-enome-components and functional correlates. Genes Dev 2006;20:3215-31; PMID:17158741; http://dx.doi.org/10.1101/gad.1464906. (Pubitemid 44904843)
    • (2006) Genes and Development , vol.20 , Issue.23 , pp. 3215-3231
    • Ting, A.H.1    McGarvey, K.M.2    Baylin, S.B.3
  • 12
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • Sparmann A, van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 2006;6:846-56; PMID:17060944; http://dx.doi.org/10.1038/nrc1991. (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 13
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • PMID:15765097; http://dx.doi.org/10.1038/ng1531
    • Fraga M F, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 2005;37:391-400; PMID:15765097; http://dx.doi.org/10.1038/ng1531.
    • (2005) Nat Genet , vol.37 , pp. 391-400
    • Fraga, M.F.1    Ballestar, E.2    Villar-Garea, A.3    Boix-Chornet, M.4    Espada, J.5    Schotta, G.6
  • 14
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • DOI 10.1038/nature03672
    • Seligson DB, Horvath S, Shi T, Yu H, Tze S, Grunstein M, et al. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 2005;435:1262-6; PMID:15988529; http://dx.doi.org/10.1038/nature03672. (Pubitemid 40943093)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 15
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
    • DOI 10.1016/S0092-8674(02)00975-3
    • Czermin B, Melfi R, McCabe D, Seitz V, Imhof A, Pirrotta V. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 2002;111:185-96; PMID:12408863; http://dx.doi.org/10.1016/S0092-8674 (02) 00975-3. (Pubitemid 35292439)
    • (2002) Cell , vol.111 , Issue.2 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    McCabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 19
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • PMID:16618801; http://dx.doi.org/10.1101/gad.381706
    • Bracken A P, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 2006;20:1123-36; PMID:16618801; http://dx.doi.org/10.1101/gad.381706.
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 20
    • 41749108163 scopus 로고    scopus 로고
    • Stem cell regulation by polycomb repressors: Postponing commitment
    • PMID:18291635; http://dx.doi.org/10.1016/j.ceb.2008.01.004
    • Pietersen AM, van Lohuizen M. Stem cell regulation by polycomb repressors: postponing commitment. Curr Opin Cell Biol 2008;20:201-7; PMID:18291635; http://dx.doi.org/10.1016/j.ceb.2008.01.004.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 201-207
    • Pietersen, A.M.1    Van Lohuizen, M.2
  • 22
    • 9644281546 scopus 로고    scopus 로고
    • Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes
    • DOI 10.1038/ng1467
    • Umlauf D, Goto Y, Cao R, Cerqueira F, Wagschal A, Zhang Y, et al. Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone meth-ylation and recruitment of Polycomb group complexes. Nat Genet 2004;36:1296-300; PMID:15516932; http://dx.doi.org/10.1038/ng1467. (Pubitemid 39577938)
    • (2004) Nature Genetics , vol.36 , Issue.12 , pp. 1296-1300
    • Umlauf, D.1    Goto, Y.2    Cao, R.3    Cerqueira, F.4    Wagschal, A.5    Zhang, Y.6    Feil, R.7
  • 23
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • DOI 10.1016/j.molcel.2004.06.020, PII S1097276504003478
    • Cao R, Zhang Y. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell 2004;15:57-67; PMID:15225548; http://dx.doi.org/10.1016/j.molcel.2004.06.020. (Pubitemid 38850219)
    • (2004) Molecular Cell , vol.15 , Issue.1 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 24
    • 3042702970 scopus 로고    scopus 로고
    • Polycomb group proteins in cell cycle progression and cancer
    • Pasini D, Bracken A P, Helin K. Polycomb group proteins in cell cycle progression and cancer. Cell Cycle 2004;3:396-400; PMID:14752272; http://dx.doi.org/10.4161/cc.3.4.773. (Pubitemid 40278219)
    • (2004) Cell Cycle , vol.3 , Issue.4 , pp. 396-400
    • Pasini, D.1    Bracken, A.P.2    Helin, K.3
  • 25
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 histone methyltransferase in cancer epigenetics
    • PMID:18723033; http://dx.doi.org/10.1016/j.mrfmmm.2008.07.010
    • Simon JA, Lange CA. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 2008;647:21-9; PMID:18723033; http://dx.doi.org/10.1016/ j.mrfmmm.2008.07.010.
    • (2008) Mutat Res , vol.647 , pp. 21-29
    • Simon, J.A.1    Lange, C.A.2
  • 26
    • 0034977239 scopus 로고    scopus 로고
    • The Polycomb-group gene Ezh2 is required for early mouse development
    • DOI 10.1128/MCB.21.13.4330-4336.2001
    • O'Carroll D, Erhardt S, Pagani M, Barton SC, Surani MA, Jenuwein T. The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol 2001;21:4330-6; PMID:11390661; http://dx.doi.org/10.1128/MCB.21.13.4330-4336. 2001. (Pubitemid 32565314)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.13 , pp. 4330-4336
    • O'Carroll, D.1    Erhardt, S.2    Pagani, M.3    Barton, S.C.4    Surani, M.A.5    Jenuwein, T.6
  • 27
    • 0043135127 scopus 로고    scopus 로고
    • Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila
    • DOI 10.1007/s00427-003-0331-y
    • Erhardt S, Lyko F, Ainscough JF-X, Surani MA, Paro R. Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila. Dev Genes Evol 2003;213:336-44; PMID:12750886; http://dx.doi.org/10.1007/s00427-003-0331-y. (Pubitemid 36949806)
    • (2003) Development Genes and Evolution , vol.213 , Issue.7 , pp. 336-344
    • Erhardt, S.1    Lyko, F.2    Ainscough, J.F.-X.3    Surani, M.A.4    Paro, R.5
  • 28
    • 0029922115 scopus 로고    scopus 로고
    • Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene
    • DOI 10.1016/0925-4773(96)00499-6
    • Hobert O, Sures I, Ciossek T, Fuchs M, Ullrich A. Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene. Mech Dev 1996;55:171-84; PMID:8861097; http://dx.doi.org/10.1016/0925-4773 (96) 00499-6. (Pubitemid 26148950)
    • (1996) Mechanisms of Development , vol.55 , Issue.2 , pp. 171-184
    • Robert, O.1    Sures, I.2    Ciossek, T.3    Fuchs, M.4    Ullrich, A.5
  • 29
    • 0030922630 scopus 로고    scopus 로고
    • Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres
    • DOI 10.1093/emboj/16.11.3219
    • Laible G, Wolf A, Dorn R, Reuter G, Nislow C, Lebersorger A, et al. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J 1997;16:3219-32; PMID:9214638; http://dx.doi.org/10.1093/emboj/16.11.3219. (Pubitemid 27234960)
    • (1997) EMBO Journal , vol.16 , Issue.11 , pp. 3219-3232
    • Laible, G.1    Wolf, A.2    Dorn, R.3    Reuter, G.4    Nislow, C.5    Lebersorger, A.6    Popkin, D.7    Pillus, L.8    Jenuwein, T.9
  • 30
    • 0037320925 scopus 로고    scopus 로고
    • Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
    • DOI 10.1038/ni876
    • Su I-H, Basavaraj A, Krutchinsky AN, Hobert O, Ullrich A, Chait BT, et al. Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat Immunol 2003;4:124-31; PMID:12496962; http://dx.doi.org/10. 1038/ni876. (Pubitemid 36193013)
    • (2003) Nature Immunology , vol.4 , Issue.2 , pp. 124-131
    • Su, I.-H.1    Basavaraj, A.2    Krutchinsky, A.N.3    Hobert, O.4    Ullrich, A.5    Chait, B.T.6    Tarakhovsky, A.7
  • 31
    • 7544230144 scopus 로고    scopus 로고
    • The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
    • DOI 10.1101/gad.1241904
    • Caretti G, Di Padova M, Micales B, Lyons GE, Sartorelli V. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev 2004;18:2627-38; PMID:15520282; http://dx.doi.org/10. 1101/gad.1241904. (Pubitemid 39453102)
    • (2004) Genes and Development , vol.18 , Issue.21 , pp. 2627-2638
    • Caretti, G.1    Di Padova, M.2    Micales, B.3    Lyons, G.E.4    Sartorelli, V.5
  • 32
    • 70349764482 scopus 로고    scopus 로고
    • Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells
    • PMID:19818710; http://dx.doi.org/10.1016/j.molcel.2009.08.008
    • Juan AH, Kumar RM, Marx JG, Young RA, Sartorelli V. Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells. Mol Cell 2009;36:61-74; PMID:19818710; http://dx.doi.org/10.1016/j. molcel.2009.08.008.
    • (2009) Mol Cell , vol.36 , pp. 61-74
    • Juan, A.H.1    Kumar, R.M.2    Marx, J.G.3    Young, R.A.4    Sartorelli, V.5
  • 33
    • 60749126576 scopus 로고    scopus 로고
    • Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma
    • PMID:19106613; http://dx.doi.org/10.4161/cc.8.1.7292
    • Ciarapica R, Russo G, Verginelli F, Raimondi L, Donfrancesco A, Rota R, et al. Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma. Cell Cycle 2009;8:172-5; PMID:19106613; http://dx.doi.org/10.4161/cc.8.1.7292.
    • (2009) Cell Cycle , vol.8 , pp. 172-175
    • Ciarapica, R.1    Russo, G.2    Verginelli, F.3    Raimondi, L.4    Donfrancesco, A.5    Rota, R.6
  • 34
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of polycomb gene silencing: Knowns and unknowns
    • PMID:19738629
    • Simon JA, Kingston RE. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 2009;10:697-708; PMID:19738629.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 35
    • 77951428293 scopus 로고    scopus 로고
    • UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogen-esis
    • PMID:20300060; http://dx.doi.org/10.1038/emboj.2010.37
    • Seenundun S, Rampalli S, Liu Q-C, Aziz A, Palii C, Hong S, et al. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogen-esis. EMBO J 2010;29:1401-11; PMID:20300060; http://dx.doi.org/10.1038/emboj.2010.37.
    • (2010) EMBO J , vol.29 , pp. 1401-1411
    • Seenundun, S.1    Rampalli, S.2    Liu, Q.-C.3    Aziz, A.4    Palii, C.5    Hong, S.6
  • 36
    • 77949409909 scopus 로고    scopus 로고
    • Epigenetic remodeling of chromatin architecture: Exploring tumor differentiation therapies in mesenchymal stem cells and sarcomas
    • PMID:19807660; http://dx.doi.org/10.2174/157488810790442859
    • Siddiqi S, Mills J, Matushansky I. Epigenetic remodeling of chromatin architecture: exploring tumor differentiation therapies in mesenchymal stem cells and sarcomas. Curr Stem Cell Res Ther 2010;5:63-73; PMID:19807660; http://dx.doi.org/10.2174/157488810790442859.
    • (2010) Curr Stem Cell Res Ther , vol.5 , pp. 63-73
    • Siddiqi, S.1    Mills, J.2    Matushansky, I.3
  • 38
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • DOI 10.1038/nature02625
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004;429:457-63; PMID:15164071; http://dx.doi.org/10.1038/nature02625. (Pubitemid 38715140)
    • (2004) Nature , vol.429 , Issue.6990 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 39
    • 27144509196 scopus 로고    scopus 로고
    • DNA methyltransferase inhibitors and the development of epigenetic cancer therapies
    • DOI 10.1093/jnci/dji311
    • Lyko F, Brown R. DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. J Natl Cancer Inst 2005;97:1498-506; PMID:16234563; http://dx.doi.org/10.1093/jnci/dji311. (Pubitemid 41631949)
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.20 , pp. 1498-1506
    • Lyko, F.1    Brown, R.2
  • 40
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • PMID:16485345; http://dx.doi.org/10.1038/nrd1930
    • Yoo CB, Jones PA. Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov 2006;5:37-50; PMID:16485345; http://dx.doi.org/10.1038/ nrd1930.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 41
    • 70350500219 scopus 로고    scopus 로고
    • Epigenetics and genetics: Polycomb group proteins: Navigators of lineage pathways led astray in cancer
    • http://dx.doi.org/10.1038/nrc2736
    • Bracken A P, Helin K. Epigenetics and genetics: Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat Rev Cancer 2009;9:1-12; http://dx.doi.org/10.1038/nrc2736.
    • (2009) Nat Rev Cancer , vol.9 , pp. 1-12
    • Bracken, A.P.1    Helin, K.2
  • 42
    • 1942502862 scopus 로고    scopus 로고
    • Different Ezh2-containing complexes target methylation of histone H1 or nucleosomal histone H3
    • DOI 10.1016/S1097-2765(04)00185-6, PII S1097276504001856
    • Kuzmichev A, Jenuwein T, Tempst P, Reinberg D. Different EZH2-containing complexes target meth-ylation of histone H1 or nucleosomal histone H3. Mol Cell 2004;14:183-93; PMID:15099518; http://dx.doi.org/10.1016/S1097-2765 (04) 00185-6. (Pubitemid 38515646)
    • (2004) Molecular Cell , vol.14 , Issue.2 , pp. 183-193
    • Kuzmichev, A.1    Jenuwein, T.2    Tempst, P.3    Reinberg, D.4
  • 43
    • 27844519267 scopus 로고    scopus 로고
    • 27 phosphorylation blocks HP1 binding
    • DOI 10.1074/jbc.C500229200
    • Daujat S, Zeissler U, Waldmann T, Happel N, Schneider R. HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding. J Biol Chem 2005;280:38090-5; PMID:16127177; http://dx.doi.org/10.1074/jbc. C500229200. (Pubitemid 41642423)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 38090-38095
    • Daujat, S.1    Zeissler, U.2    Waldmann, T.3    Happel, N.4    Schneider, R.5
  • 47
    • 35348993743 scopus 로고    scopus 로고
    • Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
    • DOI 10.1126/science.1149042
    • Lee MG, Villa R, Trojer P, Norman J, Yan K P, Reinberg D, et al. Demethylation of H3K27 regulates poly-comb recruitment and H2A ubiquitination. Science 2007;318:447-50; PMID:17761849; http://dx.doi.org/10.1126/science. 1149042. (Pubitemid 47614529)
    • (2007) Science , vol.318 , Issue.5849 , pp. 447-450
    • Min, G.L.1    Villa, R.2    Trojer, P.3    Norman, J.4    Yan, K.-P.5    Reinberg, D.6    Di Croce, L.7    Shiekhattar, R.8
  • 48
    • 38549115170 scopus 로고    scopus 로고
    • P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo
    • DOI 10.1128/MCB.01859-07
    • Ni Z, Saunders A, Fuda NJ, Yao J, Suarez J-R, Webb WW, et al. P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo. Mol Cell Biol 2008;28:1161-70; PMID:18070927; http://dx.doi.org/10.1128/ MCB.01859-07. (Pubitemid 351160071)
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.3 , pp. 1161-1170
    • Ni, Z.1    Saunders, A.2    Fuda, N.J.3    Yao, J.4    Suarez, J.-R.5    Webb, W.W.6    Lis, J.T.7


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