Heme oxygenase-1 modulates degeneration of the intervertebral disc after puncture in Bach 1 deficient mice

European Spine Journal

Volumn 21, Issue 9, 2012, Pages 1748-1757

  Ohta, Ryo ^a   Tanaka, Nobuhiro ^a   Nakanishi, Kazuyoshi ^a   Kamei, Naosuke ^a   Nakamae, Toshio ^a   Izumi, Bunichiro ^a   Fujioka, Yuki ^a   Ochi, Mitsuo ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Heme oxygenase 1; Intervertebral disc; Intervertebral disc degeneration; Oxidative stress

Indexed keywords

HEME OXYGENASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; IMMUNOHISTOLOGY; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LOW BACK PAIN; LUMBAR PUNCTURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINE RADIOGRAPHY; WILD TYPE;

AGING; ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CERVICAL VERTEBRAE; HEME OXYGENASE-1; INTERVERTEBRAL DISC DEGENERATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS;

EID: 84867996814     PISSN: 09406719     EISSN: 14320932     Source Type: Journal    
DOI: 10.1007/s00586-012-2442-5     Document Type: Article

References (29)

1. Kirkaldy-Willis WH, Farfan HF (1982) Instability of the lumbar spine. Clin Orthop Relat Res 165:110-123
2. Urban JP, Roberts S (2003) Degeneration of the intervertebral disc. Arthritis Res Ther 5:120-130
3. Tanaka N, An HS, Lim TH et al (2001) The relationship between disc degeneration and flexibility of the lumbar spine. Spine J 1:47-56
4. An HS, Masuda K, Inoue N (2006) Intervertebral disc degeneration: biological and biomechanical factors. J Orthop Sci 11:541-552
5. Seki S, Kawaguchi Y, Chiba K et al (2005) A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease. Nat Genet 37:607-612
6. Kim KW, Ha KY, Lee JS et al (2007) The apoptotic effects of oxidative stress and antiapoptotic effects of caspase inhibitors on rat notochordal cells. Spine 32:2443-2448
7. Poveda L, Hottiger M, Boos N et al (2009) Peroxynitrite induces gene expression in intervertebral disc cells. Spine 34:1127-1133
8. Kikuchi G, Yoshida T, Noguchi M (2005) Heme oxygenase and heme degradation. Biochem Biophys Res Commun 338:558-567
9. Shan Y, Lambrecht RW, Ghaziani T et al (2004) Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS. J Biol Chem 279: 51769-51774
10. Shibahara S, Muller RM, Taguchi H (1987) Transcriptional control of rat heme oxygenase by heat shock. J Biol Chem 262:12889-12892
11. Alam J, Shibahara S, Smith A (1989) Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells. J Biol Chem 264:6371-6375
12. Sun J, Hoshino H, Takaku K et al (2002) Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J 21:5216-5224
13. Poss KD, Tonegawa S (1997) Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 94:10925-10930
14. Hancock WW, Buelow R, Sayegh MH et al (1998) Antibodyinduced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes. Nat Med 4:1392-1396
15. Odaka Y, Takahashi T, Yamasaki A et al (2000) Prevention of halothane-induced hepatotoxicity by hemin pretreatment: protective role of heme oxygenase-1 induction. Biochem Pharmacol 59:871-880
16. Sun J, Brand M, Zenke Y, Tashiro S, Groudine M, Igarashi K (2004) Heme regulates the dynamic exchange of Bach1 and NFE2- related factors in the Maf transcription factor network. Proc Natl Acad Sci U S A 101:1461-1466
17. Ochiai S, Mizuno T, Deie M et al (2008) Oxidative stress reaction in the meniscus of Bach 1 deficient mice: potential prevention of meniscal degeneration. J Orthop Res 26:894-898
18. Lu DS, Shono Y, Oda I et al (1997) Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study. Spine 22:1828-1834 (discussion 34-35)
19. Boos N, Weissbach S, Rohrbach H et al (2002) Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine 27:2631-2644
20. Yang F, Leung VY, Luk KD et al (2009) Injury-induced sequential transformation of notochordal nucleus pulposus to chondrogenic and fibrocartilaginous phenotype in the mouse. J Pathol 218:113-121
21. Han B, Zhu K, Li FC et al (2008) A simple disc degeneration model induced by percutaneous needle puncture in the rat tail. Spine 33:1925-1934
22. Masuda K, Aota Y, Muehleman C et al (2005) A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration. Spine 30:5-14
23. Yamada K, Tanaka N, Nakanishi K et al (2008) Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1. J Neurosurg Spine 9:611-620
24. Davies CM, Guilak F, Weinberg JB et al (2008) Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. Osteoarthritis Cartilage 16:624-630
25. Lotz JC (2004) Animal models of intervertebral disc degeneration: lessons learned. Spine 29:2742-2750
26. Olmarker K (2008) Puncture of a lumbar intervertebral disc induces changes in spontaneous pain behavior: an experimental study in rats. Spine 33:850-855
27. Elliott DM, Sarver JJ (2004) Young investigator award winner: validation of the mouse and rat disc as mechanical models of the human lumbar disc. Spine 29:713-722
28. Sarver JJ, Elliott DM (2005) Mechanical differences between lumbar and tail discs in the mouse. J Orthop Res 23:150-155
29. Ariga K, Miyamoto S, Nakase T et al (2001) The relationship between apoptosis of endplate chondrocytes and aging and degeneration of the intervertebral disc. Spine 26:2414-2420