The message in the air: Hydrogen sulfide metabolism in chronic respiratory diseases

Respiratory Physiology and Neurobiology

Volumn 184, Issue 2, 2012, Pages 130-138

  Chen, Yahong ^a   Wang, Rui ^b  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b LAKEHEAD UNIVERSITY   (Canada)

Author keywords

Asthma; Chronic respiratory diseases; Hydrogen sulfide

Indexed keywords

ACETYLCHOLINE; BIOLOGICAL MARKER; BLEOMYCIN; CARBACHOL; CARBON MONOXIDE; CORTICOSTEROID; CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; CYTOCHROME C OXIDASE; GLUCOCORTICOID; HYDROGEN SULFIDE; MALONALDEHYDE; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHLORIDE; REACTIVE OXYGEN METABOLITE; SODIUM HYDROSULFIDE; THEOPHYLLINE; TOBACCO SMOKE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AIRWAY; ANTIBIOTIC THERAPY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ASTHMA; BACTERIAL INFECTION; BIOSYNTHESIS; BRONCHODILATATION; BRONCHUS HYPERREACTIVITY; CELL PROLIFERATION; CHRONIC INFLAMMATION; CHRONIC LUNG DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CHRONIC RESPIRATORY TRACT DISEASE; CORTICOSTEROID THERAPY; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; EXPIRED AIR; GAS CHROMATOGRAPHY; HUMAN; HYPOXIA; INFLAMMATION; INTOXICATION; LOW DRUG DOSE; LUNG ARTERY PRESSURE; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG FUNCTION; LUNG VASCULAR RESISTANCE; MAMMAL; METABOLISM; NEUROGENIC INFLAMMATION; NEUROTRANSMISSION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RESPIRATORY SYSTEM; RESPIRATORY TRACT DISEASE; REVIEW; VIRAL RESPIRATORY TRACT INFECTION;

AIR POLLUTANTS; ANIMALS; BIOLOGICAL MARKERS; CHRONIC DISEASE; HUMANS; HYDROGEN SULFIDE; LUNG; NEUROTRANSMITTER AGENTS; RESPIRATORY MECHANICS; RESPIRATORY PHYSIOLOGICAL PHENOMENA; RESPIRATORY TRACT DISEASES;

EID: 84867990155     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2012.03.009     Document Type: Review

References (76)

1. Ang S.F., Moochhala S.M., Bhatia M. Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis. Crit. Care Med. 2010, 38:619-628.
2. Anthonisen N.R., Manfreda J., Warren C.P., Hershfield E.S., Harding G.K., Nelson N.A. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann. Intern. Med. 1987, 106:196-204.
3. Badesch D.B., Abman S.H., Simonneau G., Rubin L.J., McLaughlin V.V. Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines. Chest 2007, 131:1917-1928.
4. Barker M., Hengst M., Schmid J., Buers H.J., Mittermaier B., Klemp D., Koppmann R. Volatile organic compounds in the exhaled breath of young patients with cystic fibrosis. Eur. Respir. J. 2006, 27:929-936.
5. Barnes P.J. Theophylline in chronic obstructive pulmonary disease: new horizons. Proc. Am. Thorac. Soc. 2005, 2:334-339. 340, 341.
6. Barnes P.J., Dweik R.A., Gelb A.F., Gibson P.G., George S.C., Grasemann H., Pavord I.D., Ratjen F., Silkoff P.E., Taylor D.R., Zamel N. Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest 2010, 138:682-692.
7. Baskar R., Li L., Moore P.K. Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells. FASEB J. 2007, 21:247-255.
8. Bateman E.D., Hurd S.S., Barnes P.J., Bousquet J., Drazen J.M., FitzGerald M., Gibson P., Ohta K., O'Byrne P., Pedersen S.E., Pizzichini E., Sullivan S.D., Wenzel S.E., Zar H.J. Global strategy for asthma management and prevention: GINA executive summary. Eur. Respir. J. 2008, 31:143-178.
9. Beauchamp R.J., Bus J.S., Popp J.A., Boreiko C.J., Andjelkovich D.A. A critical review of the literature on hydrogen sulfide toxicity. Crit. Rev. Toxicol. 1984, 13:25-97.
10. Belley R., Bernard N., Cote M., Paquet F., Poitras J. Hyperbaric oxygen therapy in the management of two cases of hydrogen sulfide toxicity from liquid manure. CJEM 2005, 7:257-261.
11. Benavides G.A., Squadrito G.L., Mills R.W., Patel H.D., Isbell T.S., Patel R.P., Darley-Usmar V.M., Doeller J.E., Kraus D.W. Hydrogen sulfide mediates the vasoactivity of garlic. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:17977-17982.
12. Bergeron C., Tulic M.K., Hamid Q. Airway remodelling in asthma: from benchside to clinical practice. Can. Respir. J. 2010, 17:e85-e93.
13. Bhatia M., Zhi L., Zhang H., Ng S.W., Moore P.K. Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice. Am. J. Physiol. Lung Cell Mol. Physiol. 2006, 291:L896-L904.
14. Bitterman N., Talmi Y., Lerman A., Melamed Y., Melamed Y., Taitelman U. The effect of hyperbaric oxygen on acute experimental sulfide poisoning in the rat. Toxic Appl. Pharmacol. 1986, 84:325-328.
15. Braga P.C., Dal Sasso M., Culici M., Spallino A., Marabini L., Bianchi T., Nappi G. Effects of sulphurous water on human neutrophil elastase release. Ther. Adv. Respir. Dis. 2010, 4:333-340.
16. Burnett W.W., King E.G., Grace M., Hall W.F. Hydrogen sulfide poisoning: review of 5 years' experience. Can. Med. Assoc. J. 1977, 117:1277-1280.
17. Chapman H.A. Epithelial-mesenchymal interactions in pulmonary fibrosis. Annu. Rev. Physiol. 2011, 73:413-435.
18. 2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine. J. Biol. Chem. 2004, 279:52082-52086.
19. Chen Y.H., Yao W.Z., Ding Y.L., Geng B., Lu M., Tang C.S. Effect of theophylline on endogenous hydrogen sulfide production in patients with COPD. Pulm. Pharmacol. Ther. 2008, 21:40-46.
20. Chen Y.H., Wang P.P., Wang X.M., He Y.J., Yao W.Z., Qi Y.F., Tang C.S. Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung. Cytokine 2011, 53:334-341.
21. Chen Y.H., Wu R., Geng B., Qi Y.F., Wang P.P., Yao W.Z., Tang C.S. Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. Cytokine 2009, 45:117-123.
22. Chen Y.H., Yao W.Z., Gao J.Z., Geng B., Wang P.P., Tang C.S. Serum hydrogen sulfide as a novel marker predicting bacterial involvement in patients with community-acquired lower respiratory tract infections. Respirology 2009, 14:746-752.
23. Chen Y.H., Yao W.Z., Geng B., Ding Y.L., Lu M., Zhao M.W., Tang C.S. Endogenous hydrogen sulfide in patients with COPD. Chest 2005, 128:3205-3211.
24. Christ-Crain M., Jaccard-Stolz D., Bingisser R., Gencay M.M., Huber P.R., Tamm M., Muller B. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 2004, 363:600-607.
25. Chunyu Z., Junbao D., Dingfang B., Hui Y., Xiuying T., Chaoshu T. The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats. Biochem. Biophys. Res. Commun. 2003, 302:810-816.
26. Coward W.R., Saini G., Jenkins G. The pathogenesis of idiopathic pulmonary fibrosis. Ther. Adv. Respir. Dis. 2010, 4:367-388.
27. Drakopanagiotakis F., Xifteri A., Polychronopoulos V., Bouros D. Apoptosis in lung injury and fibrosis. Eur. Respir. J. 2008, 32:1631-1638.
28. Duong T.X., Suruda A.J., Maier L.A. Interstitial fibrosis following hydrogen sulfide exposure. Am. J. Ind. Med. 2001, 40:221-224.
29. Dweik R.A., Boggs P.B., Erzurum S.C., Irvin C.G., Leigh M.W., Lundberg J.O., Olin A.C., Plummer A.L., Taylor D.R. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am. J. Respir. Crit. Care Med. 2011, 184:602-615.
30. Evans A.M., Hardie D.G., Peers C., Mahmoud A. Hypoxic pulmonary vasoconstriction: mechanisms of oxygen-sensing. Curr. Opin. Anaesthesiol. 2011, 24:13-20.
31. Fang L.P., Lin Q., Tang C.S., Liu X.M. Hydrogen sulfide suppresses migration, proliferation and myofibroblast transdifferentiation of human lung fibroblasts. Pulm. Pharmacol. Ther. 2009, 22:554-561.
32. Fang L.P., Lin Q., Tang C.S., Liu X.M. Hydrogen sulfide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells. Pharmacol. Res. 2010, 61:298-305.
33. Gajdocsy R., Horvath I. Exhaled carbon monoxide in airway diseases: from research findings to clinical relevance. J. Breath Res. 2010, 4:47102.
34. Geppetti P., Materazzi S., Nicoletti P. The transient receptor potential vanilloid 1: role in airway inflammation and disease. Eur. J. Pharmacol. 2006, 533:207-214.
35. Gharaee-Kermani M., Hu B., Phan S.H., Gyetko M.R. Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast. Curr. Med. Chem. 2009, 16:1400-1417.
36. Guidotti T.L. Occupational exposure to hydrogen sulfide in the sour gas industry: some unresolved issues. Int. Arch. Occup. Environ. Health 1994, 66:153-160.
37. Guidotti T.L. Hydrogen sulphide. Occup. Med. (Lond.) 1996, 46:367-371.
38. Gunn B., Wong R. Noxious gas exposure in the outback: two cases of hydrogen sulfide toxicity. Emerg. Med. (Fremantle) 2001, 13(2):240-246. (Review).
39. Han W., Dong Z., Dimitropoulou C., Su Y. Hydrogen sulfide ameliorates tobacco smoke-induced oxidative stress and emphysema in mice. Antioxid. Redox Signal. 2011, 15:2121-2134.
40. Hillas G., Loukides S., Kostikas K., Bakakos P. Biomarkers obtained by non-invasive methods in patients with COPD: where do we stand, what do we expect?. Curr. Med. Chem. 2009, 16:2824-2838.
41. Jeffery P.K. Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2004, 1:176-183.
42. Jin H., Cong B., Zhao B., Zhang C., Liu X., Zhou W., Shi Y., Tang C., Junbao D. Effects of hydrogen sulfide on hypoxic pulmonary vascular structural remodeling. Life Sci. 2006, 78:1299-1309.
43. Kamboures M.A., Blake D.R., Cooper D.M., Newcomb R.L., Barker M., Larson J.K., Meinardi S., Nussbaum E., Rowland F.S. Breath sulfides and pulmonary function in cystic fibrosis. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:15762-15767.
44. Kubo S., Doe I., Kurokawa Y., Kawabata A. Hydrogen sulfide causes relaxation in mouse bronchial smooth muscle. J. Pharmacol. Sci. 2007, 104:392-396.
45. Li L., Hsu A., Moore P.K. Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation-a tale of three gases!. Pharmacol. Ther. 2009, 123:386-400.
46. Li S.B., Tong X.S., Wang X.X., Jin X.H., Ye H. Regulative mechanism of budesonide on endogenous hydrogen sulfide, cystathionine-gamma-lyase and cystathionine-beta-synthase system in asthmatic rats. Zhongguo Dang Dai Er Ke Za Zhi 2010, 12:654-657.
47. Lim J.J., Liu Y.H., Khin E.S., Bian J.S. Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells. Am. J. Physiol. Cell Physiol. 2008, 295:C1261-C1270.
48. Lindenmann J., Matzi V., Anegg U., Neuboeck N., Porubsky C., Fell B., Raber T., Ratzenhofer-Komenda B., Renner H., Klemen H., Greilberger J., Haas J., Maier A., Smolle-Juettner F. Hyperbaric oxygen in the treatment of hydrogen sulphide intoxication. Acta Anaesthesiol. Scand. 2010, 54:784-785.
49. Macnee W. Right heart function in COPD. Semin. Respir. Crit. Care Med. 2010, 31:295-312.
50. Mancuso C., Navarra P., Preziosi P. Roles of nitric oxide, carbon monoxide, and hydrogen sulfide in the regulation of the hypothalamic-pituitary-adrenal axis. J. Neurochem. 2010, 113:563-575.
51. Milby T.H. Hydrogen sulfide intoxication. Review of the literature and report of unusual accident resulting in two cases of nonfatal poisoning. J. Occup. Med. 1962, 4:431-437.
52. Milby T.H., Baselt R.C. Hydrogen sulfide poisoning: clarification of some controversial issues. Am. J. Ind. Med. 1999, 35:192-195.
53. Morselli-Labate A.M., Fantini L., Pezzilli R. Hydrogen sulfide, nitric oxide and a molecular mass 66 u substance in the exhaled breath of chronic pancreatitis patients. Pancreatology 2007, 7:497-504.
54. Mustafa A.K., Sikka G., Gazi S.K., Steppan J., Jung S.M., Bhunia A.K., Barodka V.M., Gazi F.K., Barrow R.K., Wang R., Amzel L.M., Berkowitz D.E., Snyder S.H. Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. Circ. Res. 2011, 109:1259-1268.
55. Olson K.R., Whitfield N.L., Bearden S.E., St L.J., Nilson E., Gao Y., Madden J.A. Hypoxic pulmonary vasodilation: a paradigm shift with a hydrogen sulfide mechanism. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2010, 298:R51-R60.
56. 2 sensing in the carotid body. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:10719-10724.
57. Perry M.M., Hui C.K., Whiteman M., Wood M.E., Adcock I., Kirkham P., Michaeloudes C., Chung K.F. Hydrogen sulfide inhibits proliferation and release of IL-8 from human airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 2011, 45:746-752.
58. Qingyou Z., Junbao D., Weijin Z., Hui Y., Chaoshu T., Chunyu Z. Impact of hydrogen sulfide on carbon monoxide/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension. Biochem. Biophys. Res. Commun. 2004, 317:30-37.
59. Rabe K.F., Hurd S., Anzueto A., Barnes P.J., Buist S.A., Calverley P., Fukuchi Y., Jenkins C., Rodriguez-Roisin R., van Weel C., Zielinski J. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am. J. Respir. Crit. Care Med. 2007, 176:532-555.
60. Raghu G., Collard H.R., Egan J.J., Martinez F.J., Behr J., Brown K.K., Colby T.V., Cordier J.F., Flaherty K.R., Lasky J.A., Lynch D.A., Ryu J.H., Swigris J.J., Wells A.U., Ancochea J., Bouros D., Carvalho C., Costabel U., Ebina M., Hansell D.M., Johkoh T., Kim D.S., King T.J., Kondoh Y., Myers J., Muller N.L., Nicholson A.G., Richeldi L., Selman M., Dudden R.F., Griss B.S., Protzko S.L., Schunemann H.J. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am. J. Respir. Crit. Care Med. 2011, 183:788-824.
61. Raval C.M., Lee P.J. Heme oxygenase-1 in lung disease. Curr. Drug Targets 2010, 11:1532-1540.
62. Sethi S. Bacteria in exacerbations of chronic obstructive pulmonary disease: phenomenon or epiphenomenon?. Proc. Am. Thorac. Soc. 2004, 1:109-114.
63. Shaji J., Jadhav D. Breath biomarker for clinical diagnosis and different analysis technique. Res. J. Pharm. Biol. Chem. Sci. 2010, 1:639-653.
64. Shibuya N., Mikami Y., Kimura Y., Nagahara N., Kimura H. Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. J. Biochem. 2009, 146:623-626.
65. Studer S.M., Orens J.B., Rosas I., Krishnan J.A., Cope K.A., Yang S., Conte J.V., Becker P.B., Risby T.H. Patterns and significance of exhaled-breath biomarkers in lung transplant recipients with acute allograft rejection. J. Heart Lung Transplant 2001, 20:1158-1166.
66. Tanaka S., Fujimoto S., Tamagaki Y., Wakayama K., Shimada K., Yoshikawa J. Bronchial injury and pulmonary edema caused by hydrogen sulfide poisoning. Am. J. Emerg. Med. 1999, 17:427-429.
67. Tashkin D.P., Altose M.D., Bleecker E.R., Connett J.E., Kanner R.E., Lee W.W., Wise R. The lung health study: airway responsiveness to inhaled methacholine in smokers with mild to moderate airflow limitation. The Lung Health Study Research Group. Am. Rev. Respir. Dis. 1992, 145:301-310.
68. Trevisani M., Patacchini R., Nicoletti P., Gatti R., Gazzieri D., Lissi N., Zagli G., Creminon C., Geppetti P., Harrison S. Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways. Br. J. Pharmacol. 2005, 145:1123-1131.
69. Wang P., Zhang G., Wondimu T., Ross B., Wang R. Hydrogen sulfide and asthma. Exp. Physiol. 2011, 96:847-852.
70. 2S be the third endogenous gaseous transmitter?. FASEB J. 2002, 16:1792-1798.
71. Wang R. Hydrogen sulfide: a new EDRF. Kidney Int. 2009, 76:700-704.
72. Wang R. Hydrogen sulfide: the third gasotransmitter in biology and medicine. Antioxid. Redox Signal. 2010, 12:1061-1064.
73. Wang R. Toxic gas, lifesaver. Sci. Am. 2010, 302:66-71.
74. Wei H.L., Zhang C.Y., Jin H.F., Tang C.S., Du J.B. Hydrogen sulfide regulates lung tissue-oxidized glutathione and total antioxidant capacity in hypoxic pulmonary hypertensive rats. Acta Pharmacol. Sin. 2008, 29:670-679.
75. Wu R., Yao W.Z., Chen Y.H., Geng B., Tang C.S. Plasma level of endogenous hydrogen sulfide in patients with acute asthma. Beijing Da Xue Xue Bao 2008, 40:505-508.
76. Wynn T.A. Integrating mechanisms of pulmonary fibrosis. J. Exp. Med. 2011, 208:1339-1350.