메뉴 건너뛰기




Volumn 7, Issue 11, 2012, Pages 1029-1037

Advances in use of functionalized carbon nanotubes for drug design and discovery

Author keywords

Carbon nanotubes (CNTs); CNT conjugates; Drug delivery; Drug discovery; Functionalized carbon nanotubes (f CNTs); Multiwalled carbon nanotubes (MWCNTs); Nanomedicine; Nanoparticles; PEGylated CNTs; Single walled carbon nanotubes (SWCNTs)

Indexed keywords

AMPHOTERICIN; ANTIBIOTIC AGENT; DNA; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; LIPOSOME; MACROGOL; MULTI WALLED NANOTUBE; PACLITAXEL; SINGLE WALLED NANOTUBE; SMALL INTERFERING RNA;

EID: 84867977085     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.722078     Document Type: Review
Times cited : (64)

References (56)
  • 1
    • 77955486440 scopus 로고    scopus 로고
    • The role of nanobiotechnology in drug discovery
    • Jain KK. The role of nanobiotechnology in drug discovery. Adv Exp Med Biol 2009;655:37-43
    • (2009) Adv Exp Med Biol , vol.655 , pp. 37-43
    • Jain, K.K.1
  • 3
    • 77954817236 scopus 로고    scopus 로고
    • Functionalized carbon nanotubes for potential medicinal applications
    • Zhang Y, Bai Y, Yan B. Functionalized carbon nanotubes for potential medicinal applications. Drug Discov Today 2010;15:428-35
    • (2010) Drug Discov Today , vol.15 , pp. 428-435
    • Zhang, Y.1    Bai, Y.2    Yan, B.3
  • 4
    • 77953719724 scopus 로고    scopus 로고
    • The alluring potential of functionalized carbon nanotubes in drug discovery
    • Ménard-Moyon C, Venturelli E, Fabbro C, et al. The alluring potential of functionalized carbon nanotubes in drug discovery. Expert Opin Drug Discov 2010;5:691-707
    • (2010) Expert Opin Drug Discov , vol.5 , pp. 691-707
    • Ménard-Moyon, C.1    Venturelli, E.2    Fabbro, C.3
  • 5
    • 50249120140 scopus 로고    scopus 로고
    • Can the properties of carbon nanotubes influence their internalization by living cells?
    • Raffa V, Ciofani G, Nitodas S, et al. Can the properties of carbon nanotubes influence their internalization by living cells? Carbon 2008;46:1600-10
    • (2008) Carbon , vol.46 , pp. 1600-1610
    • Raffa, V.1    Ciofani, G.2    Nitodas, S.3
  • 6
    • 33646384926 scopus 로고    scopus 로고
    • Blood compatible carbon nanotubes - Nano-based neoproteoglycans
    • DOI 10.1021/la0534468
    • Murugesan S, Park TJ, Yang H, et al. Blood compatible carbon nanotubes-nano-based neoproteoglycans. Langmuir 2006;22:3461-3 (Pubitemid 43672508)
    • (2006) Langmuir , vol.22 , Issue.8 , pp. 3461-3463
    • Murugesan, S.1    Park, T.-J.2    Yang, H.3    Mousa, S.4    Linhardt, R.J.5
  • 7
    • 84864008601 scopus 로고    scopus 로고
    • Insertion of short amino-functionalized single-walled carbon nanotubes into phospholipid bilayer occurs by passive diffusion
    • Kraszewski S, Bianco A, Tarek M, Ramseyer C. Insertion of short amino-functionalized single-walled carbon nanotubes into phospholipid bilayer occurs by passive diffusion. PLoS One 2012;7:e40703
    • (2012) PLoS One , vol.7
    • Kraszewski, S.1    Bianco, A.2    Tarek, M.3    Ramseyer, C.4
  • 8
    • 77954897306 scopus 로고    scopus 로고
    • Carbohydrate functionalized carbon nanotubes and their applications
    • Gorityala BK, Ma J, Wang X, et al. Carbohydrate functionalized carbon nanotubes and their applications. Chem Soc Rev 2010;39:2925-34
    • (2010) Chem Soc Rev , vol.39 , pp. 2925-2934
    • Gorityala, B.K.1    Ma, J.2    Wang, X.3
  • 9
    • 77958597213 scopus 로고    scopus 로고
    • Improved cellular uptake of functionalized single-walled carbon nanotubes
    • Antonelli A, Serafini S, Menotta M, et al. Improved cellular uptake of functionalized single-walled carbon nanotubes. Nanotechnology 2010;21:425101
    • (2010) Nanotechnology , vol.21 , pp. 425101
    • Antonelli, A.1    Serafini, S.2    Menotta, M.3
  • 10
    • 34447116383 scopus 로고    scopus 로고
    • Fatigue resistance of aligned carbon nanotube arrays under cyclic compression
    • Suhr J, Victor P, Ci L, et al. Fatigue resistance of aligned carbon nanotube arrays under cyclic compression. Nat Nanotechnol 2006;2:417-21
    • (2006) Nat Nanotechnol , vol.2 , pp. 417-421
    • Suhr, J.1    Victor, P.2    Ci, L.3
  • 11
    • 38949105860 scopus 로고    scopus 로고
    • Functionalized carbon nanotubes in drug design and discovery
    • Prato M, Kostarelos K, Bianco A. Functionalized carbon nanotubes in drug design and discovery. Acc Chem Res 2008;41:60-8
    • (2008) Acc Chem Res , vol.41 , pp. 60-68
    • Prato, M.1    Kostarelos, K.2    Bianco, A.3
  • 12
    • 34047126554 scopus 로고    scopus 로고
    • Aqueous suspension of carbon nanotubes via non-covalent functionalization with oligothiophene-terminated poly(ethylene glycol)
    • DOI 10.1016/j.carbon.2006.12.017, PII S0008622306006208
    • Lee JU, Huh J, Kim KH, et al. Aqueous suspension of carbon nanotubes via non-covalent functionalization with oligothiophene-terminated poly(ethylene glycol). Carbon 2007;45:1051-7 (Pubitemid 46528411)
    • (2007) Carbon , vol.45 , Issue.5 , pp. 1051-1057
    • Lee, J.U.1    Huh, J.2    Kim, K.H.3    Park, C.4    Jo, W.H.5
  • 13
    • 80053942384 scopus 로고    scopus 로고
    • PEG-modified carbon nanotubes in biomedicine: Current status and challenges ahead
    • Bottini M, Rosato N, Bottini N. PEG-modified carbon nanotubes in biomedicine: current status and challenges ahead. Biomacromolecules 2011;12:3381-93
    • (2011) Biomacromolecules , vol.12 , pp. 3381-3393
    • Bottini, M.1    Rosato, N.2    Bottini, N.3
  • 14
    • 78349304285 scopus 로고    scopus 로고
    • Optimization of surface chemistry on single-walled carbon nanotubes for in vivo photothermal ablation of tumors
    • Liu X, Tao H, Yang K, et al. Optimization of surface chemistry on single-walled carbon nanotubes for in vivo photothermal ablation of tumors. Biomaterials 2011;32:144-51
    • (2011) Biomaterials , vol.32 , pp. 144-151
    • Liu, X.1    Tao, H.2    Yang, K.3
  • 15
    • 84863848106 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism and toxicity of carbon nanotubes for biomedical purposes
    • Yang ST, Luo J, Zhou Q, Wang H. Pharmacokinetics, metabolism and toxicity of carbon nanotubes for biomedical purposes. Theranostics 2012;2:271-82
    • (2012) Theranostics , vol.2 , pp. 271-282
    • Yang, S.T.1    Luo, J.2    Zhou, Q.3    Wang, H.4
  • 16
    • 77749315358 scopus 로고    scopus 로고
    • Pharmacokinetics of nanomaterials: An overview of carbon nanotubes, fullerenes and quantum dots
    • Riviere JE. Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2009;1:26-34
    • (2009) Wiley Interdiscip Rev Nanomed Nanobiotechnol , vol.1 , pp. 26-34
    • Riviere, J.E.1
  • 19
    • 23244463321 scopus 로고    scopus 로고
    • Liquid filled nanoparticles as a drug delivery tool for protein therapeutics
    • DOI 10.1016/j.biomaterials.2005.05.012, PII S014296120500400X
    • Venkatesan N, Yoshimitsu J, Ito Y, et al. Liquid filled nanoparticles as a drug delivery tool for protein therapeutics. Biomaterials 2005;26:7154-63 (Pubitemid 41095538)
    • (2005) Biomaterials , vol.26 , Issue.34 , pp. 7154-7163
    • Venkatesan, N.1    Yoshimitsu, J.2    Ito, Y.3    Shibata, N.4    Takada, K.5
  • 21
    • 80051510205 scopus 로고    scopus 로고
    • Antibody covalent immobilization on carbon nanotubes and assessment of antigen binding
    • Venturelli E, Fabbro C, Chaloin O, et al. Antibody covalent immobilization on carbon nanotubes and assessment of antigen binding. Small 2011;7:2179-87
    • (2011) Small , vol.7 , pp. 2179-2187
    • Venturelli, E.1    Fabbro, C.2    Chaloin, O.3
  • 22
    • 77952678343 scopus 로고    scopus 로고
    • Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease
    • Yang Z, Zhang Y, Yang Y, et al. Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease. Nanomedicine 2010;6:427-41
    • (2010) Nanomedicine , vol.6 , pp. 427-441
    • Yang, Z.1    Zhang, Y.2    Yang, Y.3
  • 23
    • 84867505419 scopus 로고    scopus 로고
    • In vivo degradation of functionalized carbon nanotubes after stereotactic administration in the brain cortex
    • Epub ahead of print
    • Nunes A, Bussy C, Gherardini L, et al. In vivo degradation of functionalized carbon nanotubes after stereotactic administration in the brain cortex. Nanomedicine (Lond) 2012; Epub ahead of print
    • (2012) Nanomedicine (Lond)
    • Nunes, A.1    Bussy, C.2    Gherardini, L.3
  • 24
    • 84862777853 scopus 로고    scopus 로고
    • The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2
    • Ren J, Shen S, Wang D, et al. The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2. Biomaterials 2012;33:3324-33
    • (2012) Biomaterials , vol.33 , pp. 3324-3333
    • Ren, J.1    Shen, S.2    Wang, D.3
  • 26
    • 84864209744 scopus 로고    scopus 로고
    • A feasible way to use carbon nanotubes to deliver drug molecules: Transdermal application
    • Epub ahead of print
    • Ilbasmis-Tamer S, Degim IT. A feasible way to use carbon nanotubes to deliver drug molecules: transdermal application. Expert Opin Drug Deliv 2012; Epub ahead of print
    • (2012) Expert Opin Drug Deliv
    • Ilbasmis-Tamer, S.1    Degim, I.T.2
  • 28
    • 72449186152 scopus 로고    scopus 로고
    • The effect of carbon nanotubes on drug delivery in an electro-sensitive transdermal drug delivery system
    • Im JS, Bai BCh, Lee YS. The effect of carbon nanotubes on drug delivery in an electro-sensitive transdermal drug delivery system. Biomaterials 2010;31:1414-19
    • (2010) Biomaterials , vol.31 , pp. 1414-1419
    • Im, J.S.1    Bch, B.2    Lee, Y.S.3
  • 29
    • 84861699759 scopus 로고    scopus 로고
    • Carbon nanotubes-liposomes conjugate as a platform for drug delivery into cells
    • Karchemski F, Zucker D, Barenholz Y, Regev O. Carbon nanotubes-liposomes conjugate as a platform for drug delivery into cells. J Control Release 2012;160:339-45
    • (2012) J Control Release , vol.160 , pp. 339-345
    • Karchemski, F.1    Zucker, D.2    Barenholz, Y.3    Regev, O.4
  • 30
    • 53049104252 scopus 로고    scopus 로고
    • Drug delivery with carbon nanotubes for in vivo cancer treatment
    • Liu Z, Chen K, Davis C, et al. Drug delivery with carbon nanotubes for in vivo cancer treatment. Cancer Res 2008;68:6652-60
    • (2008) Cancer Res , vol.68 , pp. 6652-6660
    • Liu, Z.1    Chen, K.2    Davis, C.3
  • 31
    • 50249159611 scopus 로고    scopus 로고
    • Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device
    • Dhar S, Liu Z, Thomale J, et al. Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. J Am Chem Soc 2008;130:11467-76
    • (2008) J Am Chem Soc , vol.130 , pp. 11467-11476
    • Dhar, S.1    Liu, Z.2    Thomale, J.3
  • 35
    • 67649970082 scopus 로고    scopus 로고
    • Current status and future prospects of nanoneurology
    • Jain KK. Current status and future prospects of nanoneurology. J Nanoneurosci 2008;1:56-64
    • (2008) J Nanoneurosci , vol.1 , pp. 56-64
    • Jain, K.K.1
  • 36
    • 84862617420 scopus 로고    scopus 로고
    • Next generation brain implant coatings and nerve regeneration via novel conductive nanocomposite development. Conf Proc
    • Antoniadou EV, Ahmad RK, Jackman RB, Seifalian AM. Next generation brain implant coatings and nerve regeneration via novel conductive nanocomposite development. Conf Proc IEEE Eng Med Biol Soc 2011;2011:3253-7
    • (2011) IEEE Eng Med Biol Soc , vol.2011 , pp. 3253-3257
    • Antoniadou, E.V.1    Ahmad, R.K.2    Jackman, R.B.3    Seifalian, A.M.4
  • 38
    • 77956201191 scopus 로고    scopus 로고
    • Carbon nanotube uptake and toxicity in the brain
    • Zhang L, Alizadeh D, Badie B. Carbon nanotube uptake and toxicity in the brain. Methods Mol Biol 2010;625:55-65
    • (2010) Methods Mol Biol , vol.625 , pp. 55-65
    • Zhang, L.1    Alizadeh, D.2    Badie, B.3
  • 39
    • 78149346495 scopus 로고    scopus 로고
    • Nonviral vectors for the delivery of small interfering RNAs to the CNS
    • Posadas I, Guerra FJ, Ceña V. Nonviral vectors for the delivery of small interfering RNAs to the CNS. Nanomedicine 2010;5:1219-36
    • (2010) Nanomedicine , vol.5 , pp. 1219-1236
    • Posadas, I.1    Guerra, F.J.2    Ceña, V.3
  • 40
    • 47349085605 scopus 로고    scopus 로고
    • Antibacterial effects of carbon nanotubes: Size does matter!
    • Kang S, Herzberg M, Rodrigues DF, Elimelech M. Antibacterial effects of carbon nanotubes: size does matter!. Langmuir 2008;24:6409-13
    • (2008) Langmuir , vol.24 , pp. 6409-6413
    • Kang, S.1    Herzberg, M.2    Rodrigues, D.F.3    Elimelech, M.4
  • 41
    • 67649109320 scopus 로고    scopus 로고
    • Carbon nanotubes in drug delivery: Focus on infectious diseases
    • Rosen Y, Elman NM. Carbon nanotubes in drug delivery: focus on infectious diseases. Expert Opin Drug Deliv 2009;6:517-30
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 517-530
    • Rosen, Y.1    Elman, N.M.2
  • 43
    • 79955125453 scopus 로고    scopus 로고
    • Antifungal activity of amphotericin B conjugated to carbon nanotubes
    • Benincasa M, Pacor S, Wu W, et al. Antifungal activity of amphotericin B conjugated to carbon nanotubes. ACS Nano 2011;5:199-208
    • (2011) ACS Nano , vol.5 , pp. 199-208
    • Benincasa, M.1    Pacor, S.2    Wu, W.3
  • 44
    • 77956295819 scopus 로고    scopus 로고
    • Structure-based design of carbon nanotubes as HIV-1 protease inhibitors: Atomistic and coarse-grained simulations
    • Cheng Y, Li D, Ji B, et al. Structure-based design of carbon nanotubes as HIV-1 protease inhibitors: atomistic and coarse-grained simulations. J Mol Graph Model 2010;29:171-7
    • (2010) J Mol Graph Model , vol.29 , pp. 171-177
    • Cheng, Y.1    Li, D.2    Ji, B.3
  • 45
    • 84856110022 scopus 로고    scopus 로고
    • Enhanced antibacterial activity of amino acids-functionalized multi walled carbon nanotubes by a simple method
    • Zardini HZ, Amiri A, Shanbedi M, et al. Enhanced antibacterial activity of amino acids-functionalized multi walled carbon nanotubes by a simple method. Colloids Surf B Biointerfaces 2012;92:196-202
    • (2012) Colloids Surf B Biointerfaces , vol.92 , pp. 196-202
    • Zardini, H.Z.1    Amiri, A.2    Shanbedi, M.3
  • 47
    • 77149125903 scopus 로고    scopus 로고
    • Single-and multi-wall carbon nanotubes versus asbestos: Are the carbon nanotubes a new health risk to humans?
    • Pacurari M, Castranova V, Vallyathan V. Single-and multi-wall carbon nanotubes versus asbestos: are the carbon nanotubes a new health risk to humans? J Toxicol Environ Health A 2010;73:378-95
    • (2010) J Toxicol Environ Health A , vol.73 , pp. 378-395
    • Pacurari, M.1    Castranova, V.2    Vallyathan, V.3
  • 48
    • 77949913083 scopus 로고    scopus 로고
    • Toxicity issues in the application of carbon nanotubes to biological systems
    • Firme CP III, Bandaru PR. Toxicity issues in the application of carbon nanotubes to biological systems. Nanomedicine 2010;6:245-56
    • (2010) Nanomedicine , vol.6 , pp. 245-256
    • Firme Iii., C.P.1    Bandaru, P.R.2
  • 49
    • 80052552513 scopus 로고    scopus 로고
    • Making carbon nanotubes biocompatible and biodegradable
    • Bianco A, Kostarelos K, Prato M. Making carbon nanotubes biocompatible and biodegradable. Chem Commun (Camb) 2011;47:10182-8
    • (2011) Chem Commun (Camb) , vol.47 , pp. 10182-10188
    • Bianco, A.1    Kostarelos, K.2    Prato, M.3
  • 50
  • 51
    • 77952289829 scopus 로고    scopus 로고
    • Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation
    • Kagan VE, Konduru NV, Feng W, et al. Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. Nat Nanotechnol 2010;5:354-9
    • (2010) Nat Nanotechnol , vol.5 , pp. 354-359
    • Kagan, V.E.1    Konduru, N.V.2    Feng, W.3
  • 52
    • 80054722093 scopus 로고    scopus 로고
    • Binding of blood proteins to carbon nanotubes reduces cytotoxicity
    • Ge C, Du J, Zhao L, et al. Binding of blood proteins to carbon nanotubes reduces cytotoxicity. Proc Natl Acad Sci USA 2011;108:16968-73
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 16968-16973
    • Ge, C.1    Du, J.2    Zhao, L.3
  • 53
    • 49749128832 scopus 로고    scopus 로고
    • Carbon-nanotube shape and individualization critical for renal excretion
    • Lacerda L, Herrero MA, Venner K, et al. Carbon-nanotube shape and individualization critical for renal excretion. Small 2008;4:1130-2
    • (2008) Small , vol.4 , pp. 1130-1132
    • Lacerda, L.1    Herrero, M.A.2    Venner, K.3
  • 55
    • 84859133277 scopus 로고    scopus 로고
    • Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice
    • Shvedova AA, Kapralov AA, Feng WH, et al. Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice. PLoS One 2012;7:e3092
    • (2012) PLoS One , vol.7
    • Shvedova, A.A.1    Kapralov, A.A.2    Feng, W.H.3
  • 56
    • 84855359265 scopus 로고    scopus 로고
    • Vitamin e renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes
    • Wang J, Sun P, Bao Y, et al. Vitamin E renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes. Toxicol In Vitro 2012;26:32-41
    • (2012) Toxicol in Vitro , vol.26 , pp. 32-41
    • Wang, J.1    Sun, P.2    Bao, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.