Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 25, 2008, Pages 8697-8702

  Chakravarty, Pavitra ^a   Marches, Radu ^a   Zimmerman, Neil S ^b   Swafford, Austin D E ^c   Bajaj, Pooja ^c   Musselman, Inga H ^c   Pantano, Paul ^c   Draper, Rockford K ^c   Vitetta, Ellen S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Immunoconjugates; Lymphoma cells; Monoclonal antibodies; Nanotechnology; Near infrared light

Indexed keywords

AVIDIN; BASILIXIMAB; CARBON NANOTUBE; CD22 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; LIPID; MONOCLONAL ANTIBODY;

ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DAUDI CELL; DISPERSION; HUMAN; HUMAN CELL; INFRARED RADIATION; LIGHT EXPOSURE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TUMOR CELL;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD22; BURKITT LYMPHOMA; CELL LINE, TUMOR; HEAT; HUMANS; IMMUNOCONJUGATES; INFRARED RAYS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; NANOTUBES, CARBON;

EID: 47249114783     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803557105     Document Type: Article

References (34)

1. Gottesman MM, Fojo T, Bates SE (2002) Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat Rev Cancer 2:48-58.
2. Weiner LM, Adams GP (2000) New approaches to antibody therapy. Oncogene 19:6144-6151.
3. von Mehren AG, Weiner LM (2003) Monoclonal anti body therapy for cancer. Annu Rev Med 54:343-369.
4. Bross PF, et al. (2001) Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res 7:1490-1496.
5. Sharkey RM, Burton J, Goldenberg DM (2005) Radioimmunotherapy of non-Hodgkin's lymphoma: A critical appraisal. Exp Rev Clin Immunol 1:47-62.
6. Ghetie MA, et al. (1996) Combination immunotoxin treatment and chemotherapy in SCID mice with advanced, disseminated Daudi lymphoma. Int J Cancer 68:93-96.
7. Wei BR, Ghetie MA, Vitetta ES (2000) The combined use of an immunotoxin and a radioimmunoconjugate to treat disseminated human B-cell lymphoma in immunode-ficient mice. Clin Cancer Res 6:631-642.
8. Spiridon Cl, et al. (2002) Targeting multiple Her-2 epitopeswith monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo. Clin Cancer Res 8:1720-1730.
9. Coleman EJ, Brooks KJ, Smallshaw JE, Vitetta ES (2006) The Fc portion of UV3, an anti-CD54 monoclonal antibody, is critical for its antitumor activity in SCID mice with human multiple myeloma or lymphoma cell lines. J Immunother 29:489-498.
10. Vitetta ES, et al. (1991) A phase I immunotoxin trial in patients with B cell lymphoma. Cancer Res 51:4052-4058.
11. Amlot PL, et al. (1993) A phase I study of an anti-CD22 deglycosylated ricin A chain immunotoxin in the treatment of B cell lymphomas resistant to conventional therapy. Blood 82:2624-2633.
12. Sausville EA, et al. (1995) Continuous infusion of the anti-CD22 immunotoxin, IgG-RFB4-SMPT-dgA in patients with B cell lymphoma: A phase I study. Blood 85:3457-3465.
13. Stone M, et al. (1996) A phase I study of bolus vs. continuous infusion of the anti-CD 19 immunotoxin, lgG-HD37-dgA in patients with B cell lymphoma. Blood 88:1188-1197.
14. Engert A, et al. (1997) A phase I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma. Blood 89:403-410.
15. + Hodgkin's and non-Hodgkin's lymphoma. Clin Cancer Res 8:1779-1786.
16. Falk MH, Issels RD (2001) Hyperthermia in oncology. Int J Hyperthermia 17:1-18.
17. Wust P, et al. (2002) Hyperthermia in combined treatment of cancer. Lancet Oncol 3:487-497.
18. Cherukuri P, et al. (2006) Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence. Proc Natl Acad Sci USA 103:18882-18886.
19. Liu Z.et al. (2007) In Vivo biodistribution and highly efficient tumor targeting of carbon nanotubes in mice. Nat Nanotechnol 2:47-52.
20. Liu Z, et al. (2008) Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc Natl Acad Sci USA 105:1410-1415.
21. Gobin AM, et al. (2007) Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy. Nano Lett 7:1929-1934.
22. Loo C, Lowery A, Halas N, West J, Drezek R (2005) Immunotargeted nanoshells for integrated cancer imaging and therapy. Nano Lett 5:709-711.
23. Huang X, El-Sayed IH, Qian W, El-Sayed MA (2006) Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J Am Chem Soc 128:2115-2120.
24. Hirsch LR, qet al. (2003) Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci USA 100:13549-13554.
25. Kam NW, O'Connell M, Wisdom JA, Dai H (2005) Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc Natl Acad Sci USA 102:11600-11605.
26. Shao N, Lu S, Wickstrom E, Panchapakesan B (2007) Integrated molecular targeting of IGF 1R and Her2 surface receptors and destruction of breast cancer cells using single-wall carbon nanotubes. Nanotechnology 18:315101-315109.
27. Weissleder R (2001) A clearer vision for in vivo imaging. Nat Biotechnol 19:316-317.
28. McDevitt MR, et al. (2007) Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes. J Nucl Med 48:1180-1189.
29. Liu Z, Sun X, Nakayama-Ratchford N, Dai H (2007) Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery. ACS Nano 1:50-56.
30. Welsher K, LiuZ, Daranciang D, Dai H (2008) Selective probing and imaging of cellsl with single-walled carbon nanotubes as near-infrared fluorescent molecules. Nano Lett 8:586-590.
31. Marches R, et al. (1995) Tumor dormancy and cell signaling III. Role of hypercross-Iinking of IgM and CD 40 on the induction of cell cycle arrest and apoptosis in lymphoma cells. Ther Immunol 2:125-136.
32. Zorbas V, et al. (2004) Preparation and characterization of individual peptide-wrapped single-walled carbon nanotubes. J Am Chem Soc I 126:7222-7227.
33. Chin S-F, et al. (2007) Amphiphilichelical peptide enhances the uptake of single-walled carbon nanotubes by living cells. Exp Biol Med 232:1236-1244.
34. Schnyder A, Krahenbuhl S, Torok M, Drewe J. Huwyler J (2004) Targeting of skeletal muscle in vitro using biotinylated immunoliposomes. Biochem J 377:61-67.