The alternative complement pathway propagates inflammation and injury in murine ischemic stroke

Journal of Immunology

Volumn 189, Issue 9, 2012, Pages 4640-4647

  Elvington, Andrew ^a   Atkinson, Carl ^a   Zhu, Hong ^a   Yu, Jin ^a   Takahashi, Kazue ^b   Stahl, Gregory L ^c   Kindy, Mark S ^a,d   Tomlinson, Stephen ^a,d  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3D; COMPLEMENT COMPONENT C6; MANNOSE BINDING LECTIN; PADGEM PROTEIN; RECOMBINANT CR2 CRRY PROTEIN; RECOMBINANT CR2 FH PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN LEVEL; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT DEPOSITION; COMPLEMENT LECTIN PATHWAY; CONTROLLED STUDY; DEMYELINATION; HISTOPATHOLOGY; IMMUNOPATHOGENESIS; INFLAMMATION; MALE; MICROTHROMBUS; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; ANTIGENS, CD59; BRAIN ISCHEMIA; COMPLEMENT C1Q; COMPLEMENT C6; COMPLEMENT FACTOR B; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT PATHWAY, ALTERNATIVE; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; INFLAMMATION MEDIATORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REPERFUSION INJURY; STROKE;

EID: 84867910274     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201904     Document Type: Article

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