Complement inhibition promotes endogenous neurogenesis and sustained anti-inflammatory neuroprotection following reperfused stroke

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Ducruet, Andrew F ^a   Zacharia, Brad E ^a   Sosunov, Sergey A ^a   Gigante, Paul R ^a   Yeh, Mason L ^a   Gorski, Justin W ^a   Otten, Marc L ^a   Hwang, Richard Y ^a   DeRosa, Peter A ^a   Hickman, Zachary L ^a   Sergot, Paulina ^a   Connolly, E Sander ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3 RECEPTOR; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3A RECEPTOR; COMPLEMENT COMPONENT C3A RECEPTOR ANTAGONIST; COMPLEMENT INHIBITOR; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MEGADOSE; GRANULOCYTE; HISTOLOGY; LOADING DRUG DOSE; LOW DRUG DOSE; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; SINGLE DRUG DOSE; STROKE; T LYMPHOCYTE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAIN ISCHEMIA; COMPLEMENT C3A; DISEASE MODELS, ANIMAL; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; NEUROGENESIS; NEUROPROTECTIVE AGENTS; RECEPTORS, COMPLEMENT; REPERFUSION INJURY; STROKE; SURVIVAL RATE; T-LYMPHOCYTES;

EID: 84862737969     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038664     Document Type: Article

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